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Directions for new developments on statistical design and analysis of small population group trials.

Orphanet journal of rare diseases

Hilgers RD, Roes K, Stallard N.
PMID: 27301273
Orphanet J Rare Dis. 2016 Jun 14;11(1):78. doi: 10.1186/s13023-016-0464-5.

BACKGROUND: Most statistical design and analysis methods for clinical trials have been developed and evaluated where at least several hundreds of patients could be recruited. These methods may not be suitable to evaluate therapies if the sample size is...

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Hilgers RD, Roes K, Stallard N. Directions for new developments on statistical design and analysis of small population group trials. Orphanet J Rare Dis. 2016;11(1):78doi: 10.1186/s13023-016-0464-5.
Hilgers, R. D., Roes, K., Stallard, N. (2016). Directions for new developments on statistical design and analysis of small population group trials. Orphanet journal of rare diseases, 11(1), 78. https://doi.org/10.1186/s13023-016-0464-5
Hilgers, Ralf-Dieter, et al. "Directions for new developments on statistical design and analysis of small population group trials." Orphanet journal of rare diseases vol. 11,1 (2016): 78. doi: https://doi.org/10.1186/s13023-016-0464-5
Hilgers RD, Roes K, Stallard N. Directions for new developments on statistical design and analysis of small population group trials. Orphanet J Rare Dis. 2016 Jun 14;11(1):78. doi: 10.1186/s13023-016-0464-5. PMID: 27301273; PMCID: PMC4908723.
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A river runs through it.

Science (New York, N.Y.)

Rose KC.
PMID: 28408565
Science. 2017 Apr 14;356(6334):146. doi: 10.1126/science.aam8047.

No abstract available.

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Rose KC. A river runs through it. Science. 2017;356(6334):146doi: 10.1126/science.aam8047.
Rose, K. C. (2017). A river runs through it. Science (New York, N.Y.), 356(6334), 146. https://doi.org/10.1126/science.aam8047
Rose, Kevin C. "A river runs through it." Science (New York, N.Y.) vol. 356,6334 (2017): 146. doi: https://doi.org/10.1126/science.aam8047
Rose KC. A river runs through it. Science. 2017 Apr 14;356(6334):146. doi: 10.1126/science.aam8047. PMID: 28408565.
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Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical.

Critical care research and practice

Bozeman MC, Ross CB.
PMID: 22454763
Crit Care Res Pract. 2012;2012:151650. doi: 10.1155/2012/151650. Epub 2012 Feb 21.

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are common complications of ruptured abdominal aortoiliac aneurysms (rAAAs) and other abdominal vascular catastrophes even in the age of endovascular therapy. Morbidity and mortality due to systemic inflammatory response syndrome (SIRS)...

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Bozeman MC, Ross CB. Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Crit Care Res Pract. 2012;2012:151650doi: 10.1155/2012/151650.
Bozeman, M. C., & Ross, C. B. (2012). Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Critical care research and practice, 2012151650. https://doi.org/10.1155/2012/151650
Bozeman, Matthew C, and Ross, Charles B. "Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical." Critical care research and practice vol. 2012 (2012): 151650. doi: https://doi.org/10.1155/2012/151650
Bozeman MC, Ross CB. Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Crit Care Res Pract. 2012;2012:151650. doi: 10.1155/2012/151650. Epub 2012 Feb 21. PMID: 22454763; PMCID: PMC3290801.
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Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical.

Critical care research and practice

Bozeman MC, Ross CB.
PMID: 22454763
Crit Care Res Pract. 2012;2012:151650. doi: 10.1155/2012/151650. Epub 2012 Feb 21.

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are common complications of ruptured abdominal aortoiliac aneurysms (rAAAs) and other abdominal vascular catastrophes even in the age of endovascular therapy. Morbidity and mortality due to systemic inflammatory response syndrome (SIRS)...

Cite
Bozeman MC, Ross CB. Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Crit Care Res Pract. 2012;2012:151650doi: 10.1155/2012/151650.
Bozeman, M. C., & Ross, C. B. (2012). Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Critical care research and practice, 2012151650. https://doi.org/10.1155/2012/151650
Bozeman, Matthew C, and Ross, Charles B. "Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical." Critical care research and practice vol. 2012 (2012): 151650. doi: https://doi.org/10.1155/2012/151650
Bozeman MC, Ross CB. Intra-abdominal hypertension and abdominal compartment syndrome in association with ruptured abdominal aortic aneurysm in the endovascular era: vigilance remains critical. Crit Care Res Pract. 2012;2012:151650. doi: 10.1155/2012/151650. Epub 2012 Feb 21. PMID: 22454763; PMCID: PMC3290801.
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Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80.

Inorganic chemistry

Stevenson S, Rose CB, Maslenikova JS, Villarreal JR, Mackey MA, Mercado BQ, Chen K, Olmstead MM, Balch AL.
PMID: 23214426
Inorg Chem. 2012 Dec 17;51(24):13096-102. doi: 10.1021/ic300888e. Epub 2012 Dec 06.

The successful preparation and isolation of the mixed-metal endohedral fullerene, LaSc(2)N@I(h)-C(80), and its structural characterization by single-crystal X-ray diffraction are reported. Results from chemically adjusting plasma temperature, energy, and reactivity (CAPTEAR) experiments indicate that a 10 wt % addition...

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Stevenson S, Rose CB, Maslenikova JS, et al. Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorg Chem. 2012;51(24):13096-102doi: 10.1021/ic300888e.
Stevenson, S., Rose, C. B., Maslenikova, J. S., Villarreal, J. R., Mackey, M. A., Mercado, B. Q., Chen, K., Olmstead, M. M., & Balch, A. L. (2012). Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorganic chemistry, 51(24), 13096-102. https://doi.org/10.1021/ic300888e
Stevenson, Steven, et al. "Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80." Inorganic chemistry vol. 51,24 (2012): 13096-102. doi: https://doi.org/10.1021/ic300888e
Stevenson S, Rose CB, Maslenikova JS, Villarreal JR, Mackey MA, Mercado BQ, Chen K, Olmstead MM, Balch AL. Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorg Chem. 2012 Dec 17;51(24):13096-102. doi: 10.1021/ic300888e. Epub 2012 Dec 06. PMID: 23214426.
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Reflectance anisotropy spectroscopy and reflection high-energy electron diffraction of submonolayer coverages of Si grown on GaAs(001) by molecular-beam epitaxy.

Physical review. B, Condensed matter

Morris SJ, Reinhardt F, Richter W, Rose KC, Rumberg J, Westwood DI, Williams RH, Woolf DA.
PMID: 9979328
Phys Rev B Condens Matter. 1995 Feb 15;51(7):4691-4694. doi: 10.1103/physrevb.51.4691.

No abstract available.

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Morris SJ, Reinhardt F, Richter W, et al. Reflectance anisotropy spectroscopy and reflection high-energy electron diffraction of submonolayer coverages of Si grown on GaAs(001) by molecular-beam epitaxy. Phys Rev B Condens Matter. 1995;51(7):4691-4694doi: 10.1103/physrevb.51.4691.
Morris, S. J., Reinhardt, F., Richter, W., Rose, K. C., Rumberg, J., Westwood, D. I., Williams, R. H., & Woolf, D. A. (1995). Reflectance anisotropy spectroscopy and reflection high-energy electron diffraction of submonolayer coverages of Si grown on GaAs(001) by molecular-beam epitaxy. Physical review. B, Condensed matter, 51(7), 4691-4694. https://doi.org/10.1103/physrevb.51.4691
Morris, et al. "Reflectance anisotropy spectroscopy and reflection high-energy electron diffraction of submonolayer coverages of Si grown on GaAs(001) by molecular-beam epitaxy." Physical review. B, Condensed matter vol. 51,7 (1995): 4691-4694. doi: https://doi.org/10.1103/physrevb.51.4691
Morris SJ, Reinhardt F, Richter W, Rose KC, Rumberg J, Westwood DI, Williams RH, Woolf DA. Reflectance anisotropy spectroscopy and reflection high-energy electron diffraction of submonolayer coverages of Si grown on GaAs(001) by molecular-beam epitaxy. Phys Rev B Condens Matter. 1995 Feb 15;51(7):4691-4694. doi: 10.1103/physrevb.51.4691. PMID: 9979328.
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Methotrexate sensitizes drug-resistant metastatic melanoma cells to .

Oncotarget

Ross KC, Chin KF, Kim D, Marion CD, Yen TJ, Bhattacharjee V.
PMID: 29568360
Oncotarget. 2018 Jan 29;9(17):13324-13336. doi: 10.18632/oncotarget.24341. eCollection 2018 Mar 02.

Acquired resistance of metastatic melanoma (MM) tumors to

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Ross KC, Chin KF, Kim D, et al. Methotrexate sensitizes drug-resistant metastatic melanoma cells to . Oncotarget. 2018;9(17):13324-13336doi: 10.18632/oncotarget.24341.
Ross, K. C., Chin, K. F., Kim, D., Marion, C. D., Yen, T. J., & Bhattacharjee, V. (2018). Methotrexate sensitizes drug-resistant metastatic melanoma cells to . Oncotarget, 9(17), 13324-13336. https://doi.org/10.18632/oncotarget.24341
Ross, Kayleigh C, et al. "Methotrexate sensitizes drug-resistant metastatic melanoma cells to ." Oncotarget vol. 9,17 (2018): 13324-13336. doi: https://doi.org/10.18632/oncotarget.24341
Ross KC, Chin KF, Kim D, Marion CD, Yen TJ, Bhattacharjee V. Methotrexate sensitizes drug-resistant metastatic melanoma cells to . Oncotarget. 2018 Jan 29;9(17):13324-13336. doi: 10.18632/oncotarget.24341. eCollection 2018 Mar 02. PMID: 29568360; PMCID: PMC5862581.
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Current Statistical Considerations and Regulatory Perspectives on the Planning of Confirmatory Basket, Umbrella, and Platform Trials.

Clinical pharmacology and therapeutics

Collignon O, Gartner C, Haidich AB, James Hemmings R, Hofner B, Pétavy F, Posch M, Rantell K, Roes K, Schiel A.
PMID: 32017052
Clin Pharmacol Ther. 2020 May;107(5):1059-1067. doi: 10.1002/cpt.1804. Epub 2020 Apr 01.

Master protocols have received a growing interest during the last years. By assigning patients to specific substudies, they aim at targeting and accelerating clinical development. Given their complexity, basket, umbrella, and platform designs have raised challenging regulatory and statistical...

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Collignon O, Gartner C, Haidich AB, et al. Current Statistical Considerations and Regulatory Perspectives on the Planning of Confirmatory Basket, Umbrella, and Platform Trials. Clin Pharmacol Ther. 2020;107(5):1059-1067doi: 10.1002/cpt.1804.
Collignon, O., Gartner, C., Haidich, A. B., James Hemmings, R., Hofner, B., Pétavy, F., Posch, M., Rantell, K., Roes, K., & Schiel, A. (2020). Current Statistical Considerations and Regulatory Perspectives on the Planning of Confirmatory Basket, Umbrella, and Platform Trials. Clinical pharmacology and therapeutics, 107(5), 1059-1067. https://doi.org/10.1002/cpt.1804
Collignon, Olivier, et al. "Current Statistical Considerations and Regulatory Perspectives on the Planning of Confirmatory Basket, Umbrella, and Platform Trials." Clinical pharmacology and therapeutics vol. 107,5 (2020): 1059-1067. doi: https://doi.org/10.1002/cpt.1804
Collignon O, Gartner C, Haidich AB, James Hemmings R, Hofner B, Pétavy F, Posch M, Rantell K, Roes K, Schiel A. Current Statistical Considerations and Regulatory Perspectives on the Planning of Confirmatory Basket, Umbrella, and Platform Trials. Clin Pharmacol Ther. 2020 May;107(5):1059-1067. doi: 10.1002/cpt.1804. Epub 2020 Apr 01. PMID: 32017052.
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Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?.

Epilepsia open

van Andel J, Ungureanu C, Arends J, Tan F, Van Dijk J, Petkov G, Kalitzin S, Gutter T, de Weerd A, Vledder B, Thijs R, van Thiel G, Roes K, Leijten F.
PMID: 29588973
Epilepsia Open. 2017 Sep 06;2(4):424-431. doi: 10.1002/epi4.12076. eCollection 2017 Dec.

OBJECTIVE: Automated seizure detection and alarming could improve quality of life and potentially prevent sudden, unexpected death in patients with severe epilepsy. As currently available systems focus on tonic-clonic seizures, we want to detect a broader range of seizure...

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van Andel J, Ungureanu C, Arends J, et al. Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?. Epilepsia Open. 2017;2(4):424-431doi: 10.1002/epi4.12076.
van Andel, J., Ungureanu, C., Arends, J., Tan, F., Van Dijk, J., Petkov, G., Kalitzin, S., Gutter, T., de Weerd, A., Vledder, B., Thijs, R., van Thiel, G., Roes, K., & Leijten, F. (2017). Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?. Epilepsia open, 2(4), 424-431. https://doi.org/10.1002/epi4.12076
van Andel, Judith, et al. "Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?." Epilepsia open vol. 2,4 (2017): 424-431. doi: https://doi.org/10.1002/epi4.12076
van Andel J, Ungureanu C, Arends J, Tan F, Van Dijk J, Petkov G, Kalitzin S, Gutter T, de Weerd A, Vledder B, Thijs R, van Thiel G, Roes K, Leijten F. Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?. Epilepsia Open. 2017 Sep 06;2(4):424-431. doi: 10.1002/epi4.12076. eCollection 2017 Dec. PMID: 29588973; PMCID: PMC5862103.
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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation.

Cell reports

Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, Woolf CJ.
PMID: 34107252
Cell Rep. 2021 Jun 08;35(10):109224. doi: 10.1016/j.celrep.2021.109224.

Drug development is hampered by poor target selection. Phenotypic screens using neurons differentiated from patient stem cells offer the possibility to validate known and discover novel disease targets in an unbiased fashion. To identify targets for managing hyperexcitability, a...

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Huang X, Roet KCD, Zhang L, et al. Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell Rep. 2021;35(10):109224doi: 10.1016/j.celrep.2021.109224.
Huang, X., Roet, K. C. D., Zhang, L., Brault, A., Berg, A. P., Jefferson, A. B., Klug-McLeod, J., Leach, K. L., Vincent, F., Yang, H., Coyle, A. J., Jones, L. H., Frost, D., Wiskow, O., Chen, K., Maeda, R., Grantham, A., Dornon, M. K., Klim, J. R., Siekmann, M. T., Zhao, D., Lee, S., Eggan, K., & Woolf, C. J. (2021). Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell reports, 35(10), 109224. https://doi.org/10.1016/j.celrep.2021.109224
Huang, Xuan, et al. "Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation." Cell reports vol. 35,10 (2021): 109224. doi: https://doi.org/10.1016/j.celrep.2021.109224
Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, Woolf CJ. Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell Rep. 2021 Jun 08;35(10):109224. doi: 10.1016/j.celrep.2021.109224. PMID: 34107252; PMCID: PMC8209673.
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Rethinking the intention-to-treat principle: one size does not fit all.

Journal of clinical epidemiology

Oude Rengerink K, Mitroiu M, Teerenstra S, Pétavy F, Roes KCB.
PMID: 32380178
J Clin Epidemiol. 2020 Sep;125:198-200. doi: 10.1016/j.jclinepi.2020.04.023. Epub 2020 May 04.

No abstract available.

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Oude Rengerink K, Mitroiu M, Teerenstra S, et al. Rethinking the intention-to-treat principle: one size does not fit all. J Clin Epidemiol. 2020;125:198-200doi: 10.1016/j.jclinepi.2020.04.023.
Oude Rengerink, K., Mitroiu, M., Teerenstra, S., Pétavy, F., & Roes, K. C. B. (2020). Rethinking the intention-to-treat principle: one size does not fit all. Journal of clinical epidemiology, 125198-200. https://doi.org/10.1016/j.jclinepi.2020.04.023
Oude Rengerink, Katrien, et al. "Rethinking the intention-to-treat principle: one size does not fit all." Journal of clinical epidemiology vol. 125 (2020): 198-200. doi: https://doi.org/10.1016/j.jclinepi.2020.04.023
Oude Rengerink K, Mitroiu M, Teerenstra S, Pétavy F, Roes KCB. Rethinking the intention-to-treat principle: one size does not fit all. J Clin Epidemiol. 2020 Sep;125:198-200. doi: 10.1016/j.jclinepi.2020.04.023. Epub 2020 May 04. PMID: 32380178.
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The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics.

Pharmaceutics

Webb C, Khadke S, Schmidt ST, Roces CB, Forbes N, Berrie G, Perrie Y.
PMID: 31817217
Pharmaceutics. 2019 Dec 04;11(12). doi: 10.3390/pharmaceutics11120653.

The aim of this work was to assess the impact of solvent selection on the microfluidic production of liposomes. To achieve this, liposomes were manufactured using small-scale and bench-scale microfluidics systems using three aqueous miscible solvents (methanol, ethanol or...

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Webb C, Khadke S, Schmidt ST, et al. The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics. Pharmaceutics. 2019;11(12)doi: 10.3390/pharmaceutics11120653.
Webb, C., Khadke, S., Schmidt, S. T., Roces, C. B., Forbes, N., Berrie, G., & Perrie, Y. (2019). The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics. Pharmaceutics, 11(12), . https://doi.org/10.3390/pharmaceutics11120653
Webb, Cameron, et al. "The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics." Pharmaceutics vol. 11,12 (2019). doi: https://doi.org/10.3390/pharmaceutics11120653
Webb C, Khadke S, Schmidt ST, Roces CB, Forbes N, Berrie G, Perrie Y. The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics. Pharmaceutics. 2019 Dec 04;11(12). doi: 10.3390/pharmaceutics11120653. PMID: 31817217; PMCID: PMC6955969.
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Showing 1 to 12 of 60 entries