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Showing 1 to 7 of 7 entries
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A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors.

Clinical and translational gastroenterology

Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE.
PMID: 23324654
Clin Transl Gastroenterol. 2012 Dec 06;3:e27. doi: 10.1038/ctg.2012.21.

OBJECTIVES: We recently identified a six-gene methylation-based biomarker panel suitable for early detection of colorectal cancer (CRC). In this study, we compared the performance of this novel epi-panel with that of previously identified DNA methylation markers in the same...

Violent Infant Surrogate Shaking: Continuous High-Magnitude Centripetal Force and Abrupt Shift in Tangential Acceleration May Explain High Risk of Subdural Hemorrhage.

Neurotrauma reports

Stray-Pedersen A, Strisland F, Rognum TO, Schiks LAH, Loeve AJ.
PMID: 34223553
Neurotrauma Rep. 2021 May 26;2(1):224-231. doi: 10.1089/neur.2021.0013. eCollection 2021.

Violent shaking is believed to be a common mechanism of injury in pediatric abusive head trauma. Typical intracranial injuries include subdural and retinal hemorrhages. Using a laboratory surrogate model we conducted experiments evaluating the head motion patterns that may...

Gene expression profile in cases of infectious death in infancy.

Pediatric research

Ferrante L, Opdal SH, Nygård S, Vege Å, Rognum TO.
PMID: 32299088
Pediatr Res. 2021 Feb;89(3):483-487. doi: 10.1038/s41390-020-0896-4. Epub 2020 Apr 16.

BACKGROUND: Genetic predispositions in cases suffering sudden unexpected infant death have been a research focus worldwide during the past decade. Despite large efforts, there is still uncertainty concerning the molecular pathogenesis of these deaths. With genetic technology in constant...

Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing.

Translational oncology

Nome T, Thomassen GO, Bruun J, Ahlquist T, Bakken AC, Hoff AM, Rognum T, Nesbakken A, Lorenz S, Sun J, Barros-Silva JD, Lind GE, Myklebost O, Teixeira MR, Meza-Zepeda LA, Lothe RA, Skotheim RI.
PMID: 24151535
Transl Oncol. 2013 Oct 01;6(5):546-53. doi: 10.1593/tlo.13457. eCollection 2013.

Colorectal cancer (CRC) is the third most common cancer disease in the Western world, and about 40% of the patients die from this disease. The cancer cells are commonly genetically unstable, but only a few low-frequency recurrent fusion genes...

Re-evaluation of abusive head trauma in Norway appears flawed.

Acta paediatrica (Oslo, Norway : 1992)

Stray-Pedersen A, Vollmer-Sandholm MJ, Aukland SM, Due-Tønnessen BJ, Grøgaard JB, Haugen OH, Myhre AK, Møller C, Osberg S, Rognum TO.
PMID: 34390511
Acta Paediatr. 2021 Aug 14; doi: 10.1111/apa.16069. Epub 2021 Aug 14.

No abstract available.

Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival.

Genome medicine

Sveen A, Agesen TH, Nesbakken A, Rognum TO, Lothe RA, Skotheim RI.
PMID: 21619627
Genome Med. 2011 May 27;3(5):32. doi: 10.1186/gm248.

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease that, on the molecular level, can be characterized by inherent genomic instabilities; chromosome instability and microsatellite instability. In the present study we analyze genome-wide disruption of pre-mRNA splicing, and propose transcriptome...

Aquaporin 4 expression in the hippocampus in sudden infant death syndrome and sudden unexplained death in childhood.

Journal of chemical neuroanatomy

Eidahl JML, Stray-Pedersen A, Rognum TO, Opdal SH.
PMID: 33945852
J Chem Neuroanat. 2021 Sep;115:101962. doi: 10.1016/j.jchemneu.2021.101962. Epub 2021 May 01.

Aquaporin 4 (AQP4) is the main membrane water channel in the brain involved in regulating water homeostasis. The water distribution in neural tissue is often dysregulated after hypoxic neural injury. Previous research has indicated that victims of sudden infant...

Showing 1 to 7 of 7 entries