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Showing 1 to 12 of 31 entries
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WITHDRAWN: PUBLISHED IN ERROR BY PUBLISHER: Lumican core protein increases melanoma cell adhesion through a beta 1-type integrin receptor.

The Journal of biological chemistry

D'Onofrio MF, Brézillon S, Baranek T, Perreau C, Radwanska A, Brassart B, Roughley PJ, Malicka-Blaszkiewicz M, Ricard-Blum S, Maquart FX, Wegrowski Y.
PMID: 17699515
J Biol Chem. 2007 Dec 12; doi: 10.1074/jbc.M701861200. Epub 2007 Dec 12.

Ahead of Print article withdrawn by publisher

Republished: Retrograde ejaculation associated with quetiapine and treatment with low-dose imipramine.

Drug and therapeutics bulletin

Roughley M, Lyall M.
PMID: 31558552
Drug Ther Bull. 2019 Dec;57(12):189-191. doi: 10.1136/dtb.2019.228539rep. Epub 2019 Sep 26.

No abstract available.

Crypsis and convergence: integrative taxonomic revision of the .

PeerJ

Oliver PM, Prasetya AM, Tedeschi LG, Fenker J, Ellis RJ, Doughty P, Moritz C.
PMID: 32025362
PeerJ. 2020 Jan 27;8:e7971. doi: 10.7717/peerj.7971. eCollection 2020.

For over two decades, assessments of geographic variation in mtDNA and small numbers of nuclear loci have revealed morphologically similar, but genetically divergent, intraspecific lineages in lizards from around the world. Subsequent morphological analyses often find subtle corresponding diagnostic...

Performance evaluation of a PET insert for preclinical MRI in stand-alone PET and simultaneous PET-MRI modes.

EJNMMI physics

Emvalomenos G, Trajanovska S, Pham BTT, Doughty P, Burnet J, Smith I, Garipov R, Gregoire MC, Sunn N, McGrath J, Meikle SR.
PMID: 34626239
EJNMMI Phys. 2021 Oct 09;8(1):68. doi: 10.1186/s40658-021-00415-1.

BACKGROUND: This study aimed to evaluate the performance of a preclinical PET insert in three configurations: as a stand-alone unit outside the MRI bore, inside the bore of a cryogen-free 3T MRI and, finally, while performing simultaneous PET/MRI studies.METHODS:...

A showcase of MA Art in Science research projects (2016-2020) that explore the boundaries of art, anatomy, biology, medicine, microbiology and public health.

Journal of visual communication in medicine

Roughley M, Manetti V, Pettigrew A, Irwin J, York-Salmon G, Charuhas S, Tsenina I, Birnbaum H, Holmes E, Niethamer N.
PMID: 34523368
J Vis Commun Med. 2021 Sep 15;1-7. doi: 10.1080/17453054.2021.1975495. Epub 2021 Sep 15.

No abstract available.

Trends in medication use in patients with type 2 diabetes mellitus: a long-term view of real-world treatment between 2000 and 2015.

Diabetes, metabolic syndrome and obesity : targets and therapy

Higgins V, Piercy J, Roughley A, Milligan G, Leith A, Siddall J, Benford M.
PMID: 27843332
Diabetes Metab Syndr Obes. 2016 Nov 01;9:371-380. doi: 10.2147/DMSO.S120101. eCollection 2016.

BACKGROUND: Despite the availability of a variety of treatments, many patients with type 2 diabetes mellitus (T2DM) are not achieving glucose control. We analyzed successive waves of the Adelphi Real World Diabetes Disease Specific Programmes (DSPs) to assess treatment...

Dopamine D1 and D2 Receptors Are Important for Learning About Neutral-Valence Relationships in Sensory Preconditioning.

Frontiers in behavioral neuroscience

Roughley S, Marcus A, Killcross S.
PMID: 34526883
Front Behav Neurosci. 2021 Aug 30;15:740992. doi: 10.3389/fnbeh.2021.740992. eCollection 2021.

Dopamine neurotransmission has been ascribed multiple functions with respect to both motivational and associative processes in reward-based learning, though these have proven difficult to tease apart. In order to better describe the role of dopamine in associative learning, this...

Modulating proton diffusion and conductivity in metal-organic frameworks by incorporation of accessible free carboxylic acid groups.

Chemical science

Rought P, Marsh C, Pili S, Silverwood IP, Sakai VG, Li M, Brown MS, Argent SP, Vitorica-Yrezabal I, Whitehead G, Warren MR, Yang S, Schröder M.
PMID: 30809366
Chem Sci. 2018 Nov 02;10(5):1492-1499. doi: 10.1039/c8sc03022g. eCollection 2019 Feb 07.

Three multi-carboxylic acid functionalised ligands have been designed, synthesised and utilised to prepare the new barium-based MOFs, MFM-510, -511, and -512, which show excellent stability to water-vapour. MFM-510 and MFM-511 show moderate proton conductivities (2.1 × 10

Cells from the skin of patients with systemic sclerosis secrete chitinase 3-like protein 1.

BBA clinical

Ho YY, Baron M, Recklies AD, Roughley PJ, Mort JS.
PMID: 26675476
BBA Clin. 2014 Jan 08;1:2-11. doi: 10.1016/j.bbacli.2013.12.001. eCollection 2014 Jun.

BACKGROUND: The chitinase-like protein, Chi3L1, is associated with increased fibrotic activity as well as inflammatory processes. The capacity of skin cells from systemic sclerosis (SSc) patients to produce Chi3L1, and the stimulation of its synthesis by cytokines or growth...

Maintenance of cell viability in axially loaded intervertebral disc organ culture.

Evidence-based spine-care journal

Awwad W, Steffen T, Roughley P, Haglund L, Ouellet J.
PMID: 23526897
Evid Based Spine Care J. 2011 Aug;2(3):51-2. doi: 10.1055/s-0030-1267113.

Consistent with EBSJ's commitment to fostering quality research, we are pleased to feature some of the most highly rated abstracts from the 9th Annual AOSpine North America Fellows Forum in Banff, Canada. Enhancing the quality of evidence in spine...

Diversification across biomes in a continental lizard radiation.

Evolution; international journal of organic evolution

Ashman LG, Bragg JG, Doughty P, Hutchinson MN, Bank S, Matzke NJ, Oliver P, Moritz C.
PMID: 29972238
Evolution. 2018 Jul 04; doi: 10.1111/evo.13541. Epub 2018 Jul 04.

Ecological opportunity is a powerful driver of evolutionary diversification, and predicts rapid lineage and phenotypic diversification following colonization of competitor-free habitats. Alternatively, topographic or environmental heterogeneity could be key to generating and sustaining diversity. We explore these hypotheses in...

Satisfaction with control of systemic lupus erythematosus and lupus nephritis: physician and patient perspectives.

Patient preference and adherence

Mozaffarian N, Lobosco S, Lu P, Roughley A, Alperovich G.
PMID: 27784995
Patient Prefer Adherence. 2016 Oct 04;10:2051-2061. doi: 10.2147/PPA.S111725. eCollection 2016.

PURPOSE: Patient satisfaction with disease control of systemic lupus erythematosus (SLE) is an important component of medical management. This analysis evaluated patient and physician satisfaction with disease control of SLE, factors associated with satisfaction/dissatisfaction, and the degree of physician-patient...

Showing 1 to 12 of 31 entries