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Haemorrhagic colitis caused by dasatinib.

Case reports in hematology

Patodi N, Sagar N, Rudzki Z, Langman G, Sharma N.
PMID: 23316400
Case Rep Hematol. 2012;2012:417106. doi: 10.1155/2012/417106. Epub 2012 Dec 22.

Gastrointestinal bleeding appears to be a common adverse event associated with dasatinib therapy. Here we present a case of a 59-year-old man with chronic myeloid leukaemia (CML) developing the rarest complication of haemorrhagic colitis with dasatinib therapy which resolved...

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Patodi N, Sagar N, Rudzki Z, et al. Haemorrhagic colitis caused by dasatinib. Case Rep Hematol. 2012;2012:417106doi: 10.1155/2012/417106.
Patodi, N., Sagar, N., Rudzki, Z., Langman, G., & Sharma, N. (2012). Haemorrhagic colitis caused by dasatinib. Case reports in hematology, 2012417106. https://doi.org/10.1155/2012/417106
Patodi, Nishant, et al. "Haemorrhagic colitis caused by dasatinib." Case reports in hematology vol. 2012 (2012): 417106. doi: https://doi.org/10.1155/2012/417106
Patodi N, Sagar N, Rudzki Z, Langman G, Sharma N. Haemorrhagic colitis caused by dasatinib. Case Rep Hematol. 2012;2012:417106. doi: 10.1155/2012/417106. Epub 2012 Dec 22. PMID: 23316400; PMCID: PMC3539334.
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Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase.

Communications biology

Maheshwari S, Shimokawa C, Rudzka K, Kline CD, Eipper BA, Mains RE, Gabelli SB, Blackburn N, Amzel LM.
PMID: 30271955
Commun Biol. 2018 Jun 25;1:74. doi: 10.1038/s42003-018-0082-y. eCollection 2018.

The structures of metalloproteins that use redox-active metals for catalysis are usually exquisitely folded in a way that they are prearranged to accept their metal cofactors. Peptidylglycine α-hydroxylating monooxygenase (PHM) is a dicopper enzyme that catalyzes hydroxylation of the...

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Maheshwari S, Shimokawa C, Rudzka K, et al. Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. Commun Biol. 2018;1:74doi: 10.1038/s42003-018-0082-y.
Maheshwari, S., Shimokawa, C., Rudzka, K., Kline, C. D., Eipper, B. A., Mains, R. E., Gabelli, S. B., Blackburn, N., & Amzel, L. M. (2018). Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. Communications biology, 174. https://doi.org/10.1038/s42003-018-0082-y
Maheshwari, Sweta, et al. "Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase." Communications biology vol. 1 (2018): 74. doi: https://doi.org/10.1038/s42003-018-0082-y
Maheshwari S, Shimokawa C, Rudzka K, Kline CD, Eipper BA, Mains RE, Gabelli SB, Blackburn N, Amzel LM. Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. Commun Biol. 2018 Jun 25;1:74. doi: 10.1038/s42003-018-0082-y. eCollection 2018. PMID: 30271955; PMCID: PMC6123673.
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Feasibility of Using a Smartwatch to Intensively Monitor Patients With Chronic Obstructive Pulmonary Disease: Prospective Cohort Study.

JMIR mHealth and uHealth

Wu R, Liaqat D, de Lara E, Son T, Rudzicz F, Alshaer H, Abed-Esfahani P, Gershon AS.
PMID: 29903700
JMIR Mhealth Uhealth. 2018 Jun 14;6(6):e10046. doi: 10.2196/10046.

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with accelerated decline in lung function, diminished quality of life, and higher mortality. Proactively monitoring patients for early signs of an exacerbation and treating them early could prevent...

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Wu R, Liaqat D, de Lara E, et al. Feasibility of Using a Smartwatch to Intensively Monitor Patients With Chronic Obstructive Pulmonary Disease: Prospective Cohort Study. JMIR Mhealth Uhealth. 2018;6(6):e10046doi: 10.2196/10046.
Wu, R., Liaqat, D., de Lara, E., Son, T., Rudzicz, F., Alshaer, H., Abed-Esfahani, P., & Gershon, A. S. (2018). Feasibility of Using a Smartwatch to Intensively Monitor Patients With Chronic Obstructive Pulmonary Disease: Prospective Cohort Study. JMIR mHealth and uHealth, 6(6), e10046. https://doi.org/10.2196/10046
Wu, Robert, et al. "Feasibility of Using a Smartwatch to Intensively Monitor Patients With Chronic Obstructive Pulmonary Disease: Prospective Cohort Study." JMIR mHealth and uHealth vol. 6,6 (2018): e10046. doi: https://doi.org/10.2196/10046
Wu R, Liaqat D, de Lara E, Son T, Rudzicz F, Alshaer H, Abed-Esfahani P, Gershon AS. Feasibility of Using a Smartwatch to Intensively Monitor Patients With Chronic Obstructive Pulmonary Disease: Prospective Cohort Study. JMIR Mhealth Uhealth. 2018 Jun 14;6(6):e10046. doi: 10.2196/10046. PMID: 29903700; PMCID: PMC6024103.
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Title: Risk Factors for the Diagnosis of Colorectal Cancer.

Cancer control : journal of the Moffitt Cancer Center

Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Góra A, Rudzki S.
PMID: 35000418
Cancer Control. 2022 Jan-Dec;29:10732748211056692. doi: 10.1177/10732748211056692.

BACKGROUND: Colorectal cancer defined as cancer of the colon or rectum, is the third most frequently diagnosed cancer in men and the second in women, and, according to the World Health Organization database GLOBOCAN, it accounts for nearly 1.4...

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Lewandowska A, Rudzki G, Lewandowski T, et al. Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer Control. 2022;29:10732748211056692doi: 10.1177/10732748211056692.
Lewandowska, A., Rudzki, G., Lewandowski, T., Stryjkowska-Góra, A., & Rudzki, S. (2022). Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer control : journal of the Moffitt Cancer Center, 2910732748211056692. https://doi.org/10.1177/10732748211056692
Lewandowska, Anna, et al. "Title: Risk Factors for the Diagnosis of Colorectal Cancer." Cancer control : journal of the Moffitt Cancer Center vol. 29 (2022): 10732748211056692. doi: https://doi.org/10.1177/10732748211056692
Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Góra A, Rudzki S. Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer Control. 2022 Jan-Dec;29:10732748211056692. doi: 10.1177/10732748211056692. PMID: 35000418; PMCID: PMC8753079.
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12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort.

Wiener klinische Wochenschrift

Deisenhammer F, Bauer A, Kavelar C, Rudzki D, Rössler A, Kimpel J, Borena W, Reindl M.
PMID: 34812944
Wien Klin Wochenschr. 2021 Dec;133(23):1265-1271. doi: 10.1007/s00508-021-01985-x. Epub 2021 Nov 23.

BACKGROUND: Short-term antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown previously. The further development remains to be determined.METHODS: We prospectively followed 29 coronavirus disease 2019 cases, mean age 44 ± 13.2 years. Except for...

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Deisenhammer F, Bauer A, Kavelar C, et al. 12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort. Wien Klin Wochenschr. 2021;133(23):1265-1271doi: 10.1007/s00508-021-01985-x.
Deisenhammer, F., Bauer, A., Kavelar, C., Rudzki, D., Rössler, A., Kimpel, J., Borena, W., & Reindl, M. (2021). 12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort. Wiener klinische Wochenschrift, 133(23), 1265-1271. https://doi.org/10.1007/s00508-021-01985-x
Deisenhammer, Florian, et al. "12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort." Wiener klinische Wochenschrift vol. 133,23 (2021): 1265-1271. doi: https://doi.org/10.1007/s00508-021-01985-x
Deisenhammer F, Bauer A, Kavelar C, Rudzki D, Rössler A, Kimpel J, Borena W, Reindl M. 12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohort. Wien Klin Wochenschr. 2021 Dec;133(23):1265-1271. doi: 10.1007/s00508-021-01985-x. Epub 2021 Nov 23. PMID: 34812944; PMCID: PMC8609251.
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Title: Risk Factors for the Diagnosis of Colorectal Cancer.

Cancer control : journal of the Moffitt Cancer Center

Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Góra A, Rudzki S.
PMID: 35000418
Cancer Control. 2022 Jan-Dec;29:10732748211056692. doi: 10.1177/10732748211056692.

BACKGROUND: Colorectal cancer defined as cancer of the colon or rectum, is the third most frequently diagnosed cancer in men and the second in women, and, according to the World Health Organization database GLOBOCAN, it accounts for nearly 1.4...

Cite
Lewandowska A, Rudzki G, Lewandowski T, et al. Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer Control. 2022;29:10732748211056692doi: 10.1177/10732748211056692.
Lewandowska, A., Rudzki, G., Lewandowski, T., Stryjkowska-Góra, A., & Rudzki, S. (2022). Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer control : journal of the Moffitt Cancer Center, 2910732748211056692. https://doi.org/10.1177/10732748211056692
Lewandowska, Anna, et al. "Title: Risk Factors for the Diagnosis of Colorectal Cancer." Cancer control : journal of the Moffitt Cancer Center vol. 29 (2022): 10732748211056692. doi: https://doi.org/10.1177/10732748211056692
Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Góra A, Rudzki S. Title: Risk Factors for the Diagnosis of Colorectal Cancer. Cancer Control. 2022 Jan-Dec;29:10732748211056692. doi: 10.1177/10732748211056692. PMID: 35000418.
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Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study.

Vaccine

Nasreen S, Wang J, Kwong JC, Crowcroft NS, Sadarangani M, Wilson SE, McGeer A, Kellner JD, Quach C, Morris SK, Sander B, Kus JV, Naus M, Hoang L, Rudzicz F, Fadel S, Marra F.
PMID: 34810001
Vaccine. 2021 Nov 19; doi: 10.1016/j.vaccine.2021.11.032. Epub 2021 Nov 19.

BACKGROUND: Invasive pneumococcal disease (IPD) burden, evaluated in Canada using reported confirmed cases in surveillance systems, is likely underestimated due to underreporting. We estimated the burden of IPD in Ontario and British Columbia (BC) by combining surveillance data with...

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Nasreen S, Wang J, Kwong JC, et al. Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study. Vaccine. 2021;doi: 10.1016/j.vaccine.2021.11.032.
Nasreen, S., Wang, J., Kwong, J. C., Crowcroft, N. S., Sadarangani, M., Wilson, S. E., McGeer, A., Kellner, J. D., Quach, C., Morris, S. K., Sander, B., Kus, J. V., Naus, M., Hoang, L., Rudzicz, F., Fadel, S., & Marra, F. (2021). Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study. Vaccine, . https://doi.org/10.1016/j.vaccine.2021.11.032
Nasreen, Sharifa, et al. "Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study." Vaccine vol. (2021). doi: https://doi.org/10.1016/j.vaccine.2021.11.032
Nasreen S, Wang J, Kwong JC, Crowcroft NS, Sadarangani M, Wilson SE, McGeer A, Kellner JD, Quach C, Morris SK, Sander B, Kus JV, Naus M, Hoang L, Rudzicz F, Fadel S, Marra F. Population-based incidence of invasive pneumococcal disease in children and adults in Ontario and British Columbia, 2002-2018: A Canadian Immunization Research Network (CIRN) study. Vaccine. 2021 Nov 19; doi: 10.1016/j.vaccine.2021.11.032. Epub 2021 Nov 19. PMID: 34810001.
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The Effect of Feed Supplementation with EM Bokashi® Multimicrobial Probiotic Preparation on Selected Parameters of Sow Colostrum and Milk as Indicators of the Specific and Nonspecific Immune Response.

Probiotics and antimicrobial proteins

Jarosz Ł, Ciszewski A, Marek A, Grądzki Z, Kaczmarek B, Rysiak A.
PMID: 34596883
Probiotics Antimicrob Proteins. 2021 Oct 01; doi: 10.1007/s12602-021-09850-z. Epub 2021 Oct 01.

The aim of the study was to determine the effect of EM Bokashi® on selected parameters of the specific and nonspecific immune response of sows by in colostrum and milk samples. The percentage of cells with expression of CD19

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Jarosz Ł, Ciszewski A, Marek A, et al. The Effect of Feed Supplementation with EM Bokashi® Multimicrobial Probiotic Preparation on Selected Parameters of Sow Colostrum and Milk as Indicators of the Specific and Nonspecific Immune Response. Probiotics Antimicrob Proteins. 2021;doi: 10.1007/s12602-021-09850-z.
Jarosz, �. �., Ciszewski, A., Marek, A., Grądzki, Z., Kaczmarek, B., & Rysiak, A. (2021). The Effect of Feed Supplementation with EM Bokashi® Multimicrobial Probiotic Preparation on Selected Parameters of Sow Colostrum and Milk as Indicators of the Specific and Nonspecific Immune Response. Probiotics and antimicrobial proteins, . https://doi.org/10.1007/s12602-021-09850-z
Jarosz, Łukasz, et al. "The Effect of Feed Supplementation with EM Bokashi® Multimicrobial Probiotic Preparation on Selected Parameters of Sow Colostrum and Milk as Indicators of the Specific and Nonspecific Immune Response." Probiotics and antimicrobial proteins vol. (2021). doi: https://doi.org/10.1007/s12602-021-09850-z
Jarosz Ł, Ciszewski A, Marek A, Grądzki Z, Kaczmarek B, Rysiak A. The Effect of Feed Supplementation with EM Bokashi® Multimicrobial Probiotic Preparation on Selected Parameters of Sow Colostrum and Milk as Indicators of the Specific and Nonspecific Immune Response. Probiotics Antimicrob Proteins. 2021 Oct 01; doi: 10.1007/s12602-021-09850-z. Epub 2021 Oct 01. PMID: 34596883.
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Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report.

Journal of personalized medicine

Urbanowicz T, Michalak M, Olasińska-Wiśniewska A, Rodzki M, Krasińska A, Perek B, Krasiński Z, Jemielity M.
PMID: 34945738
J Pers Med. 2021 Dec 01;11(12). doi: 10.3390/jpm11121266.

BACKGROUND: Carotid artery disease accounts for 30% of ischemic strokes in the general population. Numerous biomarkers have been investigated for predicting either the progression or the severity of the disease. The aim of this retrospective study was to compare...

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Urbanowicz T, Michalak M, Olasińska-Wiśniewska A, et al. Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report. J Pers Med. 2021;11(12)doi: 10.3390/jpm11121266.
Urbanowicz, T., Michalak, M., Olasińska-Wiśniewska, A., Rodzki, M., Krasińska, A., Perek, B., Krasiński, Z., & Jemielity, M. (2021). Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report. Journal of personalized medicine, 11(12), . https://doi.org/10.3390/jpm11121266
Urbanowicz, Tomasz, et al. "Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report." Journal of personalized medicine vol. 11,12 (2021). doi: https://doi.org/10.3390/jpm11121266
Urbanowicz T, Michalak M, Olasińska-Wiśniewska A, Rodzki M, Krasińska A, Perek B, Krasiński Z, Jemielity M. Monocyte/Lymphocyte Ratio and MCHC as Predictors of Collateral Carotid Artery Disease-Preliminary Report. J Pers Med. 2021 Dec 01;11(12). doi: 10.3390/jpm11121266. PMID: 34945738; PMCID: PMC8707882.
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Management of Allogeneic Stem Cell Transplantation for High-Risk AML following SARS-CoV-2 Associated Pancytopenia with Marked Bone Marrow Biopsy Alterations.

Case reports in hematology

Kaparou M, Rudzki Z, Giles H, Murthy V, Srinath S, Lloyd R, Ahmed MZ, Salhan B, Chauhan S, Kishore B, Lovell R, Horgan C, Paneesha S, Xenou E, Lokare A, Ewing J, Dassanayake H, Nikolousis E, Kanellopoulos A.
PMID: 33510919
Case Rep Hematol. 2021 Jan 21;2021:8843063. doi: 10.1155/2021/8843063. eCollection 2021.

The present study describes a patient aged 70 with very high-risk AML who successfully received a nonmyeloablative matched unrelated donor allograft shortly following SARS-CoV-2 infection, which manifested with mild cough, interstitial abnormalities on chest CT, and pancytopenia with profound...

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Kaparou M, Rudzki Z, Giles H, et al. Management of Allogeneic Stem Cell Transplantation for High-Risk AML following SARS-CoV-2 Associated Pancytopenia with Marked Bone Marrow Biopsy Alterations. Case Rep Hematol. 2021;2021:8843063doi: 10.1155/2021/8843063.
Kaparou, M., Rudzki, Z., Giles, H., Murthy, V., Srinath, S., Lloyd, R., Ahmed, M. Z., Salhan, B., Chauhan, S., Kishore, B., Lovell, R., Horgan, C., Paneesha, S., Xenou, E., Lokare, A., Ewing, J., Dassanayake, H., Nikolousis, E., & Kanellopoulos, A. (2021). Management of Allogeneic Stem Cell Transplantation for High-Risk AML following SARS-CoV-2 Associated Pancytopenia with Marked Bone Marrow Biopsy Alterations. Case reports in hematology, 20218843063. https://doi.org/10.1155/2021/8843063
Kaparou, Maria, et al. "Management of Allogeneic Stem Cell Transplantation for High-Risk AML following SARS-CoV-2 Associated Pancytopenia with Marked Bone Marrow Biopsy Alterations." Case reports in hematology vol. 2021 (2021): 8843063. doi: https://doi.org/10.1155/2021/8843063
Kaparou M, Rudzki Z, Giles H, Murthy V, Srinath S, Lloyd R, Ahmed MZ, Salhan B, Chauhan S, Kishore B, Lovell R, Horgan C, Paneesha S, Xenou E, Lokare A, Ewing J, Dassanayake H, Nikolousis E, Kanellopoulos A. Management of Allogeneic Stem Cell Transplantation for High-Risk AML following SARS-CoV-2 Associated Pancytopenia with Marked Bone Marrow Biopsy Alterations. Case Rep Hematol. 2021 Jan 21;2021:8843063. doi: 10.1155/2021/8843063. eCollection 2021. PMID: 33510919; PMCID: PMC7825359.
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Changes in the facial soft tissue profile after maxillary orthognathic surgery.

Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie

Rupperti S, Winterhalder P, Krennmair S, Holberg S, Holberg C, Mast G, Rudzki I.
PMID: 33881549
J Orofac Orthop. 2021 Apr 21; doi: 10.1007/s00056-021-00294-2. Epub 2021 Apr 21.

OBJECTIVES: To compare the changes of the soft tissue profile in relation to the displacement of the underlying hard structures in maxillary orthognathic surgery and to contribute to the esthetic prediction of the facial profile after surgical procedures.MATERIALS AND...

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Rupperti S, Winterhalder P, Krennmair S, et al. Veränderungen des fazialen Weichgewebeprofils nach maxillärer orthognather Chirurgie. Changes in the facial soft tissue profile after maxillary orthognathic surgery. J Orofac Orthop. 2021;doi: 10.1007/s00056-021-00294-2.
Rupperti, S., Winterhalder, P., Krennmair, S., Holberg, S., Holberg, C., Mast, G., & Rudzki, I. (2021). Veränderungen des fazialen Weichgewebeprofils nach maxillärer orthognather Chirurgie. Changes in the facial soft tissue profile after maxillary orthognathic surgery. Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, . https://doi.org/10.1007/s00056-021-00294-2
Rupperti, S, et al. "Veränderungen des fazialen Weichgewebeprofils nach maxillärer orthognather Chirurgie." Changes in the facial soft tissue profile after maxillary orthognathic surgery. Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie vol. (2021). doi: https://doi.org/10.1007/s00056-021-00294-2
Rupperti S, Winterhalder P, Krennmair S, Holberg S, Holberg C, Mast G, Rudzki I. Veränderungen des fazialen Weichgewebeprofils nach maxillärer orthognather Chirurgie. Changes in the facial soft tissue profile after maxillary orthognathic surgery. J Orofac Orthop. 2021 Apr 21; doi: 10.1007/s00056-021-00294-2. Epub 2021 Apr 21. PMID: 33881549.
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Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma.

Radiology case reports

Nilak YD, Nilak A, Shafeek S, Rudzki DZ, Chapman J.
PMID: 31871516
Radiol Case Rep. 2019 Nov 28;15(2):156-160. doi: 10.1016/j.radcr.2019.10.018. eCollection 2020 Feb.

Benign xanthomatous pseudotumors are rare, mass forming lesions composed of lipid laden histiocytes and tumor necrosis following chemotherapy. We present a rare case of young 36 year old male with primary mediastinal Hodgkin's lymphoma who developed xanthomatous pseudotumor mimicking...

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Nilak YD, Nilak A, Shafeek S, et al. Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma. Radiol Case Rep. 2019;15(2):156-160doi: 10.1016/j.radcr.2019.10.018.
Nilak, Y. D., Nilak, A., Shafeek, S., Rudzki, D. Z., & Chapman, J. (2020). Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma. Radiology case reports, 15(2), 156-160. https://doi.org/10.1016/j.radcr.2019.10.018
Nilak, Yash Dilip, et al. "Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma." Radiology case reports vol. 15,2 (2020): 156-160. doi: https://doi.org/10.1016/j.radcr.2019.10.018
Nilak YD, Nilak A, Shafeek S, Rudzki DZ, Chapman J. Benign histiocyte-rich pseudotumor in post treatment mediastinal Hodgkin's lymphoma. Radiol Case Rep. 2019 Nov 28;15(2):156-160. doi: 10.1016/j.radcr.2019.10.018. eCollection 2020 Feb. PMID: 31871516; PMCID: PMC6911874.
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