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Molecular mechanisms of mouse skin tumor promotion.

Cancers

Rundhaug JE, Fischer SM.
PMID: 21297902
Cancers (Basel). 2010;2(2):436-82. doi: 10.3390/cancers2020436.

Multiple molecular mechanisms are involved in the promotion of skin carcinogenesis. Induction of sustained proliferation and epidermal hyperplasia by direct activation of mitotic signaling pathways or indirectly in response to chronic wounding and/or inflammation, or due to a block...

Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer.

Journal of clinical medicine

von Maltzan K, Li Y, Rundhaug JE, Hudson LG, Fischer SM, Kusewitt DF.
PMID: 26848699
J Clin Med. 2016 Feb 03;5(2). doi: 10.3390/jcm5020021.

The Slug transcription factor plays an important role in ultraviolet radiation (UVR)-induced skin carcinogenesis, particularly in the epithelial-mesenchymal transition (EMT) occurring during tumor progression. In the present studies, we investigated the role of Slug in two-stage chemical skin carcinogenesis....

Showing 1 to 2 of 2 entries