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Showing 1 to 12 of 18 entries
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Egas Moniz: 90 Years (1927-2017) from Cerebral Angiography.

Frontiers in neuroanatomy

Artico M, Spoletini M, Fumagalli L, Biagioni F, Ryskalin L, Fornai F, Salvati M, Frati A, Pastore FS, Taurone S.
PMID: 28974927
Front Neuroanat. 2017 Sep 19;11:81. doi: 10.3389/fnana.2017.00081. eCollection 2017.

In June 2017 we celebrate the 90th anniversary of the pioneer discovery of cerebral angiography, the seminal imaging technique used for visualizing cerebral blood vessels and vascular alterations as well as other intracranial disorders. Egas Moniz (1874-1955) was the...

Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis.

Frontiers in cellular neuroscience

Natale G, Lenzi P, Lazzeri G, Falleni A, Biagioni F, Ryskalin L, Fornai F.
PMID: 26594150
Front Cell Neurosci. 2015 Nov 06;9:434. doi: 10.3389/fncel.2015.00434. eCollection 2015.

Amyotrophic lateral sclerosis (ALS) is characterized by massive loss of motor neurons. Data from ALS patients and experimental models indicate that mitochondria are severely damaged within dying or spared motor neurons. Nonetheless, recent data indicate that mitochondrial preservation, although...

Interdependency Between Autophagy and Synaptic Vesicle Trafficking: Implications for Dopamine Release.

Frontiers in molecular neuroscience

Limanaqi F, Biagioni F, Gambardella S, Ryskalin L, Fornai F.
PMID: 30186112
Front Mol Neurosci. 2018 Aug 21;11:299. doi: 10.3389/fnmol.2018.00299. eCollection 2018.

Autophagy (ATG) and the Ubiquitin Proteasome (UP) are the main clearing systems of eukaryotic cells, in that being ultimately involved in degrading damaged and potentially harmful cytoplasmic substrates. Emerging evidence implicates that, in addition to their classic catalytic function...

Observation of π^{-}K^{+} and π^{+}K^{-} Atoms.

Physical review letters

Adeva B, Afanasyev L, Allkofer Y, Amsler C, Anania A, Aogaki S, Benelli A, Brekhovskikh V, Cechak T, Chiba M, Chliapnikov P, Doskarova P, Drijard D, Dudarev A, Dumitriu D, Fluerasu D, Gorin A, Gorchakov O, Gritsay K, Guaraldo C, Gugiu M, Hansroul M, Hons Z, Horikawa S, Iwashita Y, Karpukhin V, Kluson J, Kobayashi M, Kruglov V, Kruglova L, Kulikov A, Kulish E, Kuptsov A, Lamberto A, Lanaro A, Lednicky R, Mariñas C, Martincik J, Nemenov L, Nikitin M, Okada K, Olchevskii V, Pentia M, Penzo A, Plo M, Prusa P, Rappazzo G, Romero Vidal A, Ryazantsev A, Rykalin V, Saborido J, Schacher J, Sidorov A, Smolik J, Takeutchi F, Tauscher L, Trojek T, Trusov S, Urban T, Vrba T, Yazkov V, Yoshimura Y, Zhabitsky M, Zrelov P.
PMID: 27661682
Phys Rev Lett. 2016 Sep 09;117(11):112001. doi: 10.1103/PhysRevLett.117.112001. Epub 2016 Sep 08.

The observation of hydrogenlike πK atoms, consisting of π^{-}K^{+} or π^{+}K^{-} mesons, is presented. The atoms are produced by 24  GeV/c protons from the CERN PS accelerator, interacting with platinum or nickel foil targets. The breakup (ionization) of πK...

A comparison of proton stopping power measured with proton CT and x-ray CT in fresh postmortem porcine structures.

Medical physics

DeJongh DF, DeJongh EA, Rykalin V, DeFillippo G, Pankuch M, Best AW, Coutrakon G, Duffin KL, Karonis NT, Ordoñez CE, Sarosiek C, Schulte RW, Winans JR, Block AM, Hentz CL, Welsh JS.
PMID: 34739140
Med Phys. 2021 Dec;48(12):7998-8009. doi: 10.1002/mp.15334. Epub 2021 Nov 18.

PURPOSE: Currently, calculations of proton range in proton therapy patients are based on a conversion of CT Hounsfield units of patient tissues into proton relative stopping power. Uncertainties in this conversion necessitate larger proximal and distal planned target volume...

Loud Noise Exposure Produces DNA, Neurotransmitter and Morphological Damage within Specific Brain Areas.

Frontiers in neuroanatomy

Frenzilli G, Ryskalin L, Ferrucci M, Cantafora E, Chelazzi S, Giorgi FS, Lenzi P, Scarcelli V, Frati A, Biagioni F, Gambardella S, Falleni A, Fornai F.
PMID: 28694773
Front Neuroanat. 2017 Jun 26;11:49. doi: 10.3389/fnana.2017.00049. eCollection 2017.

Exposure to loud noise is a major environmental threat to public health. Loud noise exposure, apart from affecting the inner ear, is deleterious for cardiovascular, endocrine and nervous systems and it is associated with neuropsychiatric disorders. In this study...

The Role of Cellular Prion Protein in Promoting Stemness and Differentiation in Cancer.

Cancers

Ryskalin L, Biagioni F, Busceti CL, Giambelluca MA, Morelli L, Frati A, Fornai F.
PMID: 33418999
Cancers (Basel). 2021 Jan 06;13(2). doi: 10.3390/cancers13020170.

Cellular prion protein (PrP

First Measurement of a Long-Lived π^{+}π^{-} Atom Lifetime.

Physical review letters

Adeva B, Afanasyev L, Anania A, Aogaki S, Benelli A, Brekhovskikh V, Cechak T, Chiba M, Chliapnikov PV, Doskarova P, Drijard D, Dudarev A, Dumitriu D, Fluerasu D, Gorin A, Gorchakov O, Gritsay K, Guaraldo C, Gugiu M, Hansroul M, Hons Z, Horikawa S, Iwashita Y, Karpukhin V, Kluson J, Kobayashi M, Kruglov V, Kruglova L, Kulikov A, Kulish E, Lamberto A, Lanaro A, Lednicky R, Mariñas C, Martincik J, Nemenov L, Nikitin M, Okada K, Olchevskii V, Ovsiannikov V, Pentia M, Penzo A, Plo M, Prusa P, Rappazzo GF, Romero Vidal A, Ryazantsev A, Rykalin V, Saborido J, Schacher J, Sidorov A, Smolik J, Takeutchi F, Trojek T, Trusov S, Urban T, Vrba T, Yazkov V, Yoshimura Y, Zrelov P.
PMID: 30932583
Phys Rev Lett. 2019 Mar 01;122(8):082003. doi: 10.1103/PhysRevLett.122.082003.

The adapted DIRAC experiment at the CERN PS accelerator observed for the first time long-lived hydrogenlike π^{+}π^{-} atoms, produced by protons hitting a beryllium target. A part of these atoms crossed the gap of 96 mm between the target...

The Baseline Structure of the Enteric Nervous System and Its Role in Parkinson's Disease.

Life (Basel, Switzerland)

Natale G, Ryskalin L, Morucci G, Lazzeri G, Frati A, Fornai F.
PMID: 34440476
Life (Basel). 2021 Jul 22;11(8). doi: 10.3390/life11080732.

The gastrointestinal (GI) tract is provided with a peculiar nervous network, known as the enteric nervous system (ENS), which is dedicated to the fine control of digestive functions. This forms a complex network, which includes several types of neurons,...

Reconstructed and Real Proton Radiographs for Image-Guidance in Proton Beam Therapy.

Journal of radiation oncology

Miller C, Altoos B, DeJongh EA, Pankuch M, DeJongh DF, Rykalin V, Ordoñez CE, Karonis NT, Winans JR, Coutrakon G, Welsh JS.
PMID: 33042477
J Radiat Oncol. 2019 Mar;8(1):97-101. doi: 10.1007/s13566-019-00376-0. Epub 2019 Mar 19.

One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty...

Author Correction: A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.

Scientific reports

Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA.
PMID: 31249326
Sci Rep. 2019 Jun 28;9(1):9574. doi: 10.1038/s41598-019-45691-1.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

The Effects of Amphetamine and Methamphetamine on the Release of Norepinephrine, Dopamine and Acetylcholine From the Brainstem Reticular Formation.

Frontiers in neuroanatomy

Ferrucci M, Limanaqi F, Ryskalin L, Biagioni F, Busceti CL, Fornai F.
PMID: 31133823
Front Neuroanat. 2019 May 10;13:48. doi: 10.3389/fnana.2019.00048. eCollection 2019.

Amphetamine (AMPH) and methamphetamine (METH) are widely abused psychostimulants, which produce a variety of psychomotor, autonomic and neurotoxic effects. The behavioral and neurotoxic effects of both compounds (from now on defined as AMPHs) stem from a fair molecular and...

Showing 1 to 12 of 18 entries