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Showing 1 to 12 of 130 entries
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Porcine bladder urothelial, myofibroblast, and detrusor muscle cells: characterization and ATP release.

Frontiers in pharmacology

Cheng Y, Mansfield KJ, Sandow SL, Sadananda P, Burcher E, Moore KH.
PMID: 21713125
Front Pharmacol. 2011 Jun 07;2:27. doi: 10.3389/fphar.2011.00027. eCollection 2011.

ATP is released from the bladder mucosa in response to stretch, but the cell types responsible are unclear. Our aim was to isolate and characterize individual populations of urothelial, myofibroblast, and detrusor muscle cells in culture, and to examine...

Idiopathic dental pulp calcifications in a tertiary care setting in South India.

Journal of conservative dentistry : JCD

Satheeshkumar PS, Mohan MP, Saji S, Sadanandan S, George G.
PMID: 23349577
J Conserv Dent. 2013 Jan;16(1):50-5. doi: 10.4103/0972-0707.105299.

BACKGROUND: Dental pulp calcifications are unique and represent the dental pulp regenerative process. Dental pulp calcifications are sometimes routine findings in oral radiographs and may later serve as an important diagnostic criterion for a hidden aspect of systemic illness.OBJECTIVE:...

Synthesis and evaluation of iron-doped titania/silane based hydrogel for the adsorptional photocatalytic degradation of Victoria blue under visible light.

Journal of colloid and interface science

Anirudhan TS, Divya PL, Nima J, Sandeep S.
PMID: 25168582
J Colloid Interface Sci. 2014 Nov 15;434:48-58. doi: 10.1016/j.jcis.2014.07.030. Epub 2014 Aug 07.

Novel photocatalyst, poly(itaconic acid-co-2-acrylamido-2-methylpropane-1-sulfonic acid) iron doped titania/silane was successfully prepared by the polymerization of iron doped titania/silane and two functional monomers, itaconic acid and 2-acrylamido-2-methylpropane-1-sulfonic acid in aqueous solution using ethylene glycol dimethacrylate as cross-linker and benzoylperoxide as...

Effect of maternal and neonatal factors on cord blood thyroid stimulating hormone.

Indian journal of endocrinology and metabolism

Lakshminarayana SG, Sadanandan NP, Mehaboob AK, Gopaliah LR.
PMID: 27186547
Indian J Endocrinol Metab. 2016 May-Jun;20(3):317-23. doi: 10.4103/2230-8210.179998.

BACKGROUND: Congenital hypothyroidism (CH) is most common preventable cause of mental retardation in children. Cord blood Thyroid Stimulating Hormone (CBTSH) level is an accepted screening tool for CH.OBJECTIVES: To study CBTSH profile in neonates born at tertiary care referral...

Towards global health security: response to the May 2018 Nipah virus outbreak linked to .

BMJ global health

Sadanadan R, Arunkumar G, Laserson KF, Heretik KH, Singh S, Mourya DT, Gangakhedkar RR, Gupta N, Sharma R, Dhuria M, Jain SK, Nichol S, Gupta P, Bhargava B.
PMID: 30483413
BMJ Glob Health. 2018 Nov 09;3(6):e001086. doi: 10.1136/bmjgh-2018-001086. eCollection 2018.

No abstract available.

Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.

Oncogene

Wagner S, Vlachogiannis G, De Haven Brandon A, Valenti M, Box G, Jenkins L, Mancusi C, Self A, Manodoro F, Assiotis I, Robinson P, Chauhan R, Rust AG, Matthews N, Eason K, Khan K, Starling N, Cunningham D, Sadanandam A, Isacke CM, Kirkin V, Valeri N, Whittaker SR.
PMID: 31147600
Oncogene. 2019 Jul;38(28):5746. doi: 10.1038/s41388-019-0835-1.

A correction to this paper has been published and can be accessed via a link at the top of the paper.

Inhibition of .

ACS omega

Nijampatnam B, Zhang H, Cai X, Michalek SM, Wu H, Velu SE.
PMID: 30087944
ACS Omega. 2018 Jul 31;3(7):8378-8385. doi: 10.1021/acsomega.8b00367. Epub 2018 Jul 30.

Removal of oral biofilms involves the use of broad-spectrum antimicrobials, which eradicate both pathogenic and protective oral commensal species. Ideal therapeutics for dental caries should be able to selectively inhibit pathogenic biofilms caused by

Melatonin-A Potent Therapeutic for Stroke and Stroke-Related Dementia.

Antioxidants (Basel, Switzerland)

Sadanandan N, Cozene B, Cho J, Park YJ, Saft M, Gonzales-Portillo B, Borlongan CV.
PMID: 32731545
Antioxidants (Basel). 2020 Jul 28;9(8). doi: 10.3390/antiox9080672.

Secreted by the pineal gland to regulate the circadian rhythm, melatonin is a powerful antioxidant that has been used to combat oxidative stress in the central nervous system. Melatonin-based therapies have been shown to provide neuroprotective effects in the...

Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Kingsbury C, Shear A, Heyck M, Sadanandan N, Zhang H, Gonzales-Portillo B, Cozene B, Sheyner M, Navarro-Torres L, García-Sánchez J, Lee JY, Borlongan CV.
PMID: 34427146
J Cereb Blood Flow Metab. 2021 Dec;41(12):3200-3212. doi: 10.1177/0271678X211039598. Epub 2021 Aug 24.

Stroke remains a significant unmet need in the clinic with few therapeutic options. We, and others, have implicated the role of inflammatory microbiota in stroke secondary cell death. Elucidating this inflammation microbiome as a biomarker may improve stroke diagnosis...

Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage.

Nature communications

Carotenuto P, Amato F, Lampis A, Rae C, Hedayat S, Previdi MC, Zito D, Raj M, Guzzardo V, Sclafani F, Lanese A, Parisi C, Vicentini C, Said-Huntingford I, Hahne JC, Hallsworth A, Kirkin V, Young K, Begum R, Wotherspoon A, Kouvelakis K, Azevedo SX, Michalarea V, Upstill-Goddard R, Rao S, Watkins D, Starling N, Sadanandam A, Chang DK, Biankin AV, Jamieson NB, Scarpa A, Cunningham D, Chau I, Workman P, Fassan M, Valeri N, Braconi C.
PMID: 34795259
Nat Commun. 2021 Nov 18;12(1):6738. doi: 10.1038/s41467-021-27099-6.

FOLFIRINOX, a combination of chemotherapy drugs (Fluorouracil, Oxaliplatin, Irinotecan -FOI), provides the best clinical benefit in pancreatic ductal adenocarcinoma (PDAC) patients. In this study we explore the role of miRNAs (MIR) as modulators of chemosensitivity to identify potential biomarkers...

Mesenchymal Stem Cell-Induced Anti-Neuroinflammation Against Traumatic Brain Injury.

Cell transplantation

Cozene B, Sadanandan N, Farooq J, Kingsbury C, Park YJ, Wang ZJ, Moscatello A, Saft M, Cho J, Gonzales-Portillo B, Borlongan CV.
PMID: 34559583
Cell Transplant. 2021 Jan-Dec;30:9636897211035715. doi: 10.1177/09636897211035715.

Traumatic brain injury (TBI) is a pervasive and damaging form of acquired brain injury (ABI). Acute, subacute, and chronic cell death processes, as a result of TBI, contribute to the disease progression and exacerbate outcomes. Extended neuroinflammation can worsen...

Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity.

Nanomedicine : nanotechnology, biology, and medicine

Sadanandan P, Payne NL, Sun G, Ashokan A, Gowd SG, Lal A, Satheesh Kumar MK, Pulakkat S, Nair SV, Menon KN, Bernard CCA, Koyakutty M.
PMID: 34748963
Nanomedicine. 2021 Nov 05;40:102481. doi: 10.1016/j.nano.2021.102481. Epub 2021 Nov 05.

Tolerance induction is central to the suppression of autoimmunity. Here, we engineered the preferential uptake of nano-conjugated autoantigens by spleen-resident macrophages to re-introduce self-tolerance and suppress autoimmunity. The brain autoantigen, myelin oligodendrocyte glycoprotein (MOG), was conjugated to 200 or...

Showing 1 to 12 of 130 entries