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Showing 1 to 12 of 25 entries
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Design of a synthetic luminescent probe from a biomolecule binding domain: selective detection of AU-rich mRNA sequences.

Chemical science

Raibaut L, Vasseur W, Shimberg GD, Saint-Pierre C, Ravanat JL, Michel SLJ, Sénèque O.
PMID: 28451295
Chem Sci. 2017 Feb 01;8(2):1658-1664. doi: 10.1039/c6sc04086a. Epub 2016 Nov 16.

We report the design of a luminescent sensor based upon the zinc finger (ZF) protein TIS11d, that allows for the selective time-resolved detection of the UUAUUUAUU sequence of the 3'-untranslated region of messenger RNA. This sensor is composed of...

[An individual and collective approach to the continuity of care].

Sante publique (Vandoeuvre-les-Nancy, France)

Saint-Pierre M, Sévigny A.
PMID: 19863015
Sante Publique. 2009 May-Jun;21(3):241-51.

Anthony Giddens' theory of structuring offers a comprehensive rationale that explains and allows understanding of the duality of individual and collective action. It takes into account both organisational structures and individual agents' actions and, most importantly, it highlights the...

Multidisciplinary Collaboration in the Treatment of Patients With Type 2 Diabetes in Primary Care: Analysis Using Process Mining.

Journal of medical Internet research

Conca T, Saint-Pierre C, Herskovic V, Sepúlveda M, Capurro D, Prieto F, Fernandez-Llatas C.
PMID: 29636315
J Med Internet Res. 2018 Apr 10;20(4):e127. doi: 10.2196/jmir.8884.

BACKGROUND: Public health in several countries is characterized by a shortage of professionals and a lack of economic resources. Monitoring and redesigning processes can foster the success of health care institutions, enabling them to provide a quality service while...

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Hypertension (Dallas, Tex. : 1979)

Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB.
PMID: 28739976
Hypertension. 2017 Jul 24; doi: 10.1161/HYPERTENSIONAHA.117.09438. Epub 2017 Jul 24.

Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood pressure has the potential to identify new pharmacological targets for the treatment of hypertension. To discover additional novel...

Three Decades of Malignant Pleural Mesothelioma: An Academic Center Experience.

Clinical lung cancer

Nasser A, Baird A, Saint-Pierre MD, Amjadi K, Laurie S, Wheatley-Price P.
PMID: 33893043
Clin Lung Cancer. 2021 Sep;22(5):441-448. doi: 10.1016/j.cllc.2021.03.011. Epub 2021 Mar 27.

BACKGROUND: Malignant pleural mesothelioma (MPM) remains a challenging disease to manage. In the past few decades, extrapleural pneumonectomy (EPP), pemetrexed-based chemotherapy, and indwelling pleural catheters were introduced to MPM care with variable levels of efficacy and evidence.PATIENTS AND METHODS:...

Hydrogen Production at a NiO Photocathode Based on a Ruthenium Dye-Cobalt Diimine Dioxime Catalyst Assembly: Insights from Advanced Spectroscopy and Post-operando Characterization.

ACS applied materials & interfaces

Giannoudis E, Bold S, Müller C, Schwab A, Bruhnke J, Queyriaux N, Gablin C, Leonard D, Saint-Pierre C, Gasparutto D, Aldakov D, Kupfer S, Artero V, Dietzek B, Chavarot-Kerlidou M.
PMID: 34637266
ACS Appl Mater Interfaces. 2021 Oct 27;13(42):49802-49815. doi: 10.1021/acsami.1c12138. Epub 2021 Oct 12.

The production of hydrogen by efficient, low-cost, and integrated photoelectrochemical water splitting processes represents an important target for the ecological transition. This challenge can be addressed thanks to bioinspired chemistry and artificial photosynthesis approaches by designing dye-sensitized photocathodes for...

Malignant Pleural Mesothelioma Outcomes in the Era of Combined Platinum and Folate Antimetabolite Chemotherapy.

Lung cancer international

Saint-Pierre MD, Pease C, Mithoowani H, Zhang T, Nicholas GA, Laurie SA, Wheatley-Price P.
PMID: 26316950
Lung Cancer Int. 2015;2015:590148. doi: 10.1155/2015/590148. Epub 2015 Mar 02.

Introduction. Malignant pleural mesothelioma (MPM) is associated with a poor prognosis. Palliative platinum-based chemotherapy may help to improve symptoms and prolong life. Since 2004, the platinum is commonly partnered with a folate antimetabolite. We performed a review investigating if...

[Health impact assessment: a structured approach to integrating health in all policies].

Sante publique (Vandoeuvre-les-Nancy, France)

Valentini H, Saint-Pierre L.
PMID: 23473042
Sante Publique. 2012 Nov-Dec;24(6):479-82.

No abstract available.

A comparative study of three methods for detecting association of quantitative traits in samples of related subjects.

BMC proceedings

Saint Pierre A, Vitezica Z, Martinez M.
PMID: 20017988
BMC Proc. 2009 Dec 15;3:S122. doi: 10.1186/1753-6561-3-s7-s122.

We used Genetic Analysis Workshop 16 Problem 3 Framingham Heart Study simulated data set to compare methods for association analysis of quantitative traits in related individuals. More specifically, we investigated type I error and relative power of three approaches:...

Influence of a parallelism defect of the external medium on the electrical impedance of a piezoelectric inserted element.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Saint-Pierre N, Jayet Y, Tatibouet J, Baboux JC.
PMID: 18244245
IEEE Trans Ultrason Ferroelectr Freq Control. 1998;45(4):906-11. doi: 10.1109/58.710555.

When a piezoelectric element is inserted in a medium, the viscoelastic properties of this medium can be deduced from the measurement of the electrical impedance of this insert, by means of optimization techniques, if all the concerned interfaces exhibit...

Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.

Molecular psychiatry

Rieux M, Alpaugh M, Sciacca G, Saint-Pierre M, Masnata M, Denis HL, Lévesque SA, Herrmann F, Bazenet C, Garneau AP, Isenring P, Truant R, Oueslati A, Gould PV, Ast A, Wanker EE, Lacroix S, Cicchetti F.
PMID: 32514103
Mol Psychiatry. 2021 Sep;26(9):5441-5463. doi: 10.1038/s41380-020-0787-4. Epub 2020 Jun 08.

Huntington's disease (HD) is a monogenic neurodegenerative disorder resulting from a mutation in the huntingtin gene. This leads to the expression of the mutant huntingtin protein (mHTT) which provokes pathological changes in both the central nervous system (CNS) and...

Retrospective evaluation of the prognostic utility of plasma lactate concentration and serial lactate measurements in dogs and cats presented to the emergency room (January 2012 - December 2016): 4863 cases.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Saint-Pierre LM, Hopper K, Epstein SE.
PMID: 34343401
J Vet Emerg Crit Care (San Antonio). 2021 Aug 03; doi: 10.1111/vec.13106. Epub 2021 Aug 03.

OBJECTIVE: To determine the prognostic significance of plasma lactate concentration, plasma lactate clearance, and delta lactate in dogs and cats presented to an emergency room (ER).DESIGN: Retrospective study.SETTING: University teaching hospital.ANIMALS: A total of 8,321 animals with a plasma...

Showing 1 to 12 of 25 entries