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Effect of helicokinins and ACE inhibitors on water balance and development of Heliothis virescens larvae.

Journal of insect physiology

Seinsche A, Dyker H, Lösel P, Backhaus D, Scherkenbeck J.
PMID: 10891570
J Insect Physiol. 2000 Nov 01;46(11):1423-1431. doi: 10.1016/s0022-1910(00)00065-2.

The diuretic activity of the helicokinins I (YFSPWG-amide), II (VRFSPWG-amide) and III (KVKFSAWG-amide) was tested on Heliothis virescens larvae. All three kinins increased fluid secretion in isolated Malpighian tubules in a dose-dependent manner. Injections into the haemolymph caused a...

Sequence-Selective Covalent CaaX-Box Receptors Prevent Farnesylation of Oncogenic Ras Proteins and Impact MAPK/PI3 K Signaling.

ChemMedChem

Franz M, Mörchen B, Degenhart C, Gülden D, Shkura O, Wolters D, Koch U, Klebl B, Stoll R, Helfrich I, Scherkenbeck J.
PMID: 33899342
ChemMedChem. 2021 Aug 19;16(16):2504-2514. doi: 10.1002/cmdc.202100167. Epub 2021 May 19.

Oncogenic Ras proteins are implicated in the most common life-threatening cancers. Despite intense research over the past two decades, the progress towards small-molecule inhibitors has been limited. One reason for this failure is that Ras proteins interact with their...

Detection of major and minor sex pheromone components by the male codling moth Cydia pomonella (Lepidoptera: Tortricidae).

Journal of insect physiology

Zebitz CP, Scherkenbeck J, Lindemann M, Lösel PM, Ebbinghaus D.
PMID: 12770443
J Insect Physiol. 1997 Nov;44(1):49-58. doi: 10.1016/s0022-1910(97)00101-7.

Electroantennograms (EAGs) recorded from the antennae of male Cydia pomonella L. in response to stimulation with doses of the main sex pheromone component E8,E10-dodecadienol (Codlemone) ranging from 5ng to 500&mgr;g did not differ in their amplitudes from responses obtained...

Anthelmintic PF1022A: stepwise solid-phase synthesis of a cyclodepsipeptide containing .

Tetrahedron

Lüttenberg S, Sondermann F, Scherkenbeck J.
PMID: 32287426
Tetrahedron. 2012 Feb 25;68(8):2068-2073. doi: 10.1016/j.tet.2011.12.026. Epub 2011 Dec 16.

Cyclodepsipeptides of the enniation-, PF1022-, and verticilide-family represent a diverse class of highly interesting natural products with respect to their manifold biological activities. However, until now no stepwise solid-phase synthesis has been accomplished due to the difficult combination of

Showing 1 to 4 of 4 entries