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Showing 1 to 12 of 16 entries
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Spectral karyotyping and SNP microarray analysis define uniparental disomy (UPD) as a novel mutational mechanism in MSI- and CSI-colorectal cancers.

Cellular oncology : the official journal of the International Society for Cellular Oncology

Melcher R, Zopf W, Hartmann E, Rosenwald A, Hoehn H, Schmid M, Kudlich T, Scheurlen M, Luehrs H.
PMID: 18936529
Cell Oncol. 2008;30(6):507. doi: 10.3233/clo-2008-0452.

No abstract available.

Wnt/β-Catenin Signaling Regulates CXCR4 Expression and [.

Diagnostics (Basel, Switzerland)

Weich A, Rogoll D, Gawlas S, Mayer L, Weich W, Pongracz J, Kudlich T, Meining A, Scheurlen M.
PMID: 33671498
Diagnostics (Basel). 2021 Feb 22;11(2). doi: 10.3390/diagnostics11020367.

Loss of Somatostatin Receptor 2 (SSTR2) expression and rising CXC Chemokine Receptor Type 4 (CXCR4) expression are associated with dedifferentiation in neuroendocrine tumors (NET). In NET, CXCR4 expression is associated with enhanced metastatic and invasive potential and worse prognosis...

State-of-the-art surgery for Crohn's disease: Part I-small intestine/ileal disease.

Langenbeck's archives of surgery

Kavalukas SL, Scheurlen KM, Galandiuk S.
PMID: 34738167
Langenbecks Arch Surg. 2021 Nov 04; doi: 10.1007/s00423-021-02324-4. Epub 2021 Nov 04.

The management of Crohn's disease has evolved significantly over the past 20 years. The arrival of biologic therapies has altered not only the management and outcomes but also rates for refractory disease requiring surgery. New surgical techniques have paralleled...

Itaconate and leptin affecting PPARγ in M2 macrophages: A potential link to early-onset colorectal cancer.

Surgery

Scheurlen KM, Snook DL, Walter MN, Cook CN, Fiechter CR, Pan J, Beal RJ, Galandiuk S.
PMID: 34876290
Surgery. 2021 Dec 04; doi: 10.1016/j.surg.2021.10.054. Epub 2021 Dec 04.

BACKGROUND: Along with the rising incidence of obesity, there has been an increase in patients diagnosed with early-onset colorectal cancer (

Combined Neurophysiologic and Neuroimaging Approach to Reveal the Structure-Function Paradox in Cervical Myelopathy.

Neurology

Scheuren PS, David G, Kipling Kramer JL, Jutzeler CR, Hupp M, Freund P, Curt A, Hubli M, Rosner J.
PMID: 34380751
Neurology. 2021 Aug 11; doi: 10.1212/WNL.0000000000012643. Epub 2021 Aug 11.

OBJECTIVE: To explore the so-called "structure-function paradox" in individuals with focal spinal lesions by means of tract-specific MRI coupled with multi-modal evoked potentials and quantitative sensory testing.METHODS: Individuals with signs and symptoms attributable to cervical myelopathy (i.e., no evidence...

A Systematic Review of Safety Reporting in Acute Spinal Cord Injury Clinical Trials: Challenges and Recommendations.

Journal of neurotrauma

Aspinall P, Harrison L, Scheuren P, Cragg JJ, Ferguson AR, Guest JD, Hsieh J, Jones L, Kirshblum S, Lammertse D, Kwon BK, Kramer JLK.
PMID: 33899507
J Neurotrauma. 2021 Aug 01;38(15):2047-2054. doi: 10.1089/neu.2020.7540. Epub 2021 Jun 03.

Accurate safety information in published clinical trials guides the assessment of risk-benefit, as well as the design of future clinical trials. Comprehensive reporting of adverse events, toxicity, and discontinuations from acute spinal cord injury clinical trials is an essential...

A highly crystalline anthracene-based MOF-74 series featuring electrical conductivity and luminescence.

Nanoscale

Scheurle PI, Mähringer A, Jakowetz AC, Hosseini P, Richter AF, Wittstock G, Medina DD, Bein T.
PMID: 31660561
Nanoscale. 2019 Nov 21;11(43):20949-20955. doi: 10.1039/c9nr05431f. Epub 2019 Oct 29.

Recently, a small group of metal-organic frameworks (MOFs) has been discovered featuring substantial charge transport properties and electrical conductivity, hence promising to broaden the scope of potential MOF applications in fields such as batteries, fuel cells and supercapacitors. In...

Clinical trials and tribulations: lessons from spinal cord injury studies registered on ClinicalTrials.gov.

Spinal cord

Warner FM, Bailey NG, Scheuren PS, Lütolf R, McGregor R, Banga R, Hsieh JTC, Kramer JLK.
PMID: 34480090
Spinal Cord. 2021 Dec;59(12):1256-1260. doi: 10.1038/s41393-021-00699-1. Epub 2021 Sep 03.

STUDY DESIGN: Article.OBJECTIVE: ClinicalTrials.gov is an online trial registry that provides public access to information on past, present, and future clinical trials. While increasing transparency in research, the quality of the information provided in trial registrations is highly variable....

Increased Expression of Long Non-coding RNA H19 is Associated With Colon Cancer Recurrence.

The Journal of surgical research

O'Brien SJ, Scheurlen K, Rochet A, Fiechter C, Paas M, Pan J, Rai SN, Galandiuk S.
PMID: 34520983
J Surg Res. 2021 Sep 11;269:59-68. doi: 10.1016/j.jss.2021.08.004. Epub 2021 Sep 11.

BACKGROUND: Colon cancer is a leading cause of cancer-related death. Long non-coding (Lnc) RNAs are critical mediators of tumor biology. H19 is a well-characterized lncRNA involved in p53 regulation and cancer progression. A specific colon cancer data set was...

Comorbidities as an Indication for Metabolic Surgery.

Visceral medicine

Schwarz AC, Billeter AT, Scheurlen KM, Blüher M, Müller-Stich BP.
PMID: 30498706
Visc Med. 2018 Oct;34(5):381-387. doi: 10.1159/000493291. Epub 2018 Oct 28.

Metabolic diseases, comprising type 2 diabetes mellitus (T2DM), dyslipidemia, and non-alcoholic steatohepatitis (NASH), are rapidly increasing worldwide. Conservative medical therapy, including the newly available drugs, has only limited effects and does neither influence survival or the development of micro-...

CXCR4-Directed PET/CT in Patients with Newly Diagnosed Neuroendocrine Carcinomas.

Diagnostics (Basel, Switzerland)

Weich A, Werner RA, Buck AK, Hartrampf PE, Serfling SE, Scheurlen M, Wester HJ, Meining A, Kircher S, Higuchi T, Pomper MG, Rowe SP, Lapa C, Kircher M.
PMID: 33805264
Diagnostics (Basel). 2021 Mar 29;11(4). doi: 10.3390/diagnostics11040605.

We aimed to elucidate the diagnostic potential of the C-X-C motif chemokine receptor 4 (CXCR4)-directed positron emission tomography (PET) tracer

[Value of galactography for the diagnostic work-up of pathological nipple discharge in multimodal breast diagnostics : Part 1: An online survey among German breast care centers.].

Der Radiologe

Scheurlen K, Schnitzer A, Krammer J, Kaiser C, Schönberg SO, Wasser K.
PMID: 24233401
Radiologe. 2013 Nov 15; doi: 10.1007/s00117-013-2572-8. Epub 2013 Nov 15.

PURPOSE: Galactography has been used in cases of pathological discharge for decades. Meanwhile other methods, such as high-resolution ultrasound (US) and magnetic resonance mammography (MRM) have been established for modern multimodal breast imaging. A survey among certified German breast...

Showing 1 to 12 of 16 entries