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Showing 1 to 12 of 274 entries
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DNA methylation profile of triple negative breast cancer-specific genes comparing lymph node positive patients to lymph node negative patients.

Scientific reports

Mathe A, Wong-Brown M, Locke WJ, Stirzaker C, Braye SG, Forbes JF, Clark SJ, Avery-Kiejda KA, Scott RJ.
PMID: 27671774
Sci Rep. 2016 Sep 27;6:33435. doi: 10.1038/srep33435.

Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype with no targeted treatment available. Our previous study identified 38 TNBC-specific genes with altered expression comparing tumour to normal samples. This study aimed to establish whether DNA...

Expression of renin-angiotensin system (RAS) components in endometrial cancer.

Endocrine connections

Delforce SJ, Lumbers ER, Corbisier de Meaultsart C, Wang Y, Proietto A, Otton G, Scurry J, Verrills NM, Scott RJ, Pringle KG.
PMID: 27956412
Endocr Connect. 2017 Jan;6(1):9-19. doi: 10.1530/EC-16-0082. Epub 2016 Dec 12.

A dysfunctional endometrial renin-angiotensin system (RAS) could aid the growth and spread of endometrial cancer. To determine if the RAS is altered in endometrial cancer, we measured RAS gene expression and protein levels in 30 human formalin-fixed, paraffin-embedded (FFPE)...

The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance.

Frontiers in cardiovascular medicine

Gourraud JB, Barc J, Thollet A, Le Scouarnec S, Le Marec H, Schott JJ, Redon R, Probst V.
PMID: 27200363
Front Cardiovasc Med. 2016 Apr 25;3:9. doi: 10.3389/fcvm.2016.00009. eCollection 2016.

For the last 10 years, applying new sequencing technologies to thousands of whole exomes has revealed the high variability of the human genome. Extreme caution should thus be taken to avoid misinterpretation when associating rare genetic variants to disease...

School Maladjustments of Some Mentally Superior Patients in a Psychiatric Clinic.

The Psychological clinic

Schott EL.
PMID: 28909598
Psychol Clin. 1932 Sep-Nov;21(3):202-207.

No abstract available.

Is hemochromatosis a risk factor for Alzheimer's disease?.

Journal of Alzheimer's disease : JAD

Connor JR, Milward EA, Moalem S, Sampietro M, Boyer P, Percy ME, Vergani C, Scott RJ, Chorney M.
PMID: 12214033
J Alzheimers Dis. 2001 Oct;3(5):471-477. doi: 10.3233/jad-2001-3506.

Excess iron accumulation in the brain is a consistent observation in Alzheimer's Disease. Iron affects amyloid precursor protein (AbetaPP) processing and promotes deposition of Abeta. Iron is also among the most potent biological toxins because of its ability to...

The Inheritance of Resistance to SALMONELLA AERTRYCKE in Various Strains of Mice.

Genetics

Schott RG.
PMID: 17246651
Genetics. 1932 Mar;17(2):203-29. doi: 10.1093/genetics/17.2.203.

No abstract available.

Removal of pentachlorophenol from aqueous solutions by dolomitic sorbents.

Journal of colloid and interface science

Marouf R, Khelifa N, Marouf-Khelifa K, Schott J, Khelifa A.
PMID: 16376921
J Colloid Interface Sci. 2006 May 01;297(1):45-53. doi: 10.1016/j.jcis.2005.10.030. Epub 2005 Dec 27.

The partial decomposition of dolomite carried out within the temperature range 600-1000 degrees C provides new sorbents, called dolomitic sorbents. Their surface properties and identification by X-ray diffraction are discussed. The lowest specific surface area value was found for...

Patients' perception of the value of levocetirizine in allergic diseases : a multicentre observational study in Germany.

Clinical drug investigation

Klimek L, Wrede H, Schott BC, Hansen I.
PMID: 17532705
Clin Drug Investig. 2005;25(9):609-14. doi: 10.2165/00044011-200525090-00006.

No abstract available.

Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease.

Hereditary cancer in clinical practice

Bowden NA, Croft A, Scott RJ.
PMID: 19725988
Hered Cancer Clin Pract. 2007 Jun 15;5(2):79-96. doi: 10.1186/1897-4287-5-2-79.

Gene expression profiling is a powerful method by which alterations in gene expression can be interrogated in a single experiment. The disease familial adenomatous polyposis (FAP) is associated with germline mutations in the APC gene, which result in aberrant...

Familial breast and bowel cancer: does it exist?.

Hereditary cancer in clinical practice

Scott RJ, Ashton KA.
PMID: 20233481
Hered Cancer Clin Pract. 2004 Feb 15;2(1):25-9. doi: 10.1186/1897-4287-2-1-25.

There is much debate in the literature about familial predispositions to breast and bowel cancers yet little evidence is forthcoming to suggest that there are susceptibility genes that can account for such kindreds. Within the context of known susceptibility...

MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.

Hereditary cancer in clinical practice

Talseth-Palmer BA, McPhillips M, Groombridge C, Spigelman A, Scott RJ.
PMID: 20487569
Hered Cancer Clin Pract. 2010 May 21;8(1):5. doi: 10.1186/1897-4287-8-5.

BACKGROUND: Approximately 10% of Lynch syndrome families have a mutation in MSH6 and fewer families have a mutation in PMS2. It is assumed that the cancer incidence is the same in families with mutations in MSH6 as in families...

Gene expression profiling of xeroderma pigmentosum.

Hereditary cancer in clinical practice

Bowden NA, Tooney PA, Scott RJ.
PMID: 20223010
Hered Cancer Clin Pract. 2006 May 15;4(2):103-10. doi: 10.1186/1897-4287-4-2-103.

Xeroderma pigmentosum (XP) is a rare recessive disorder that is characterized by extreme sensitivity to UV light. UV light exposure results in the formation of DNA damage such as cyclobutane dimers and (6-4) photoproducts. Nucleotide excision repair (NER) orchestrates...

Showing 1 to 12 of 274 entries