Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 6 of 6 entries
Sorted by: Best Match Show Resources per page
Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

BMC chemical biology

Chène P, Rudloff J, Schoepfer J, Furet P, Meier P, Qian Z, Schlaeppi JM, Schmitz R, Radimerski T.
PMID: 19128485
BMC Chem Biol. 2009 Jan 07;9:1. doi: 10.1186/1472-6769-9-1.

BACKGROUND: Topoisomerase II poisons are in clinical use as anti-cancer therapy for decades and work by stabilizing the enzyme-induced DNA breaks. In contrast, catalytic inhibitors block the enzyme before DNA scission. Although several catalytic inhibitors of topoisomerase II have...

Does Gender Moderate Factors Associated with Whether Spouses Are the Sole Providers of IADL Care to Their Partners?.

Research on aging

Feld S, Dunkle RE, Schroepfer T, Shen HW.
PMID: 21818168
Res Aging. 2010 Jul 01;32(4):499-526. doi: 10.1177/0164027510361461.

We explored whether gender moderated the influence of other factors on solo spousal caregiving. The subsample (N = 452) from the AHEAD study included elderly care recipients (CRs) receiving IADL assistance and their spouses. Logistic regression modeled the likelihood...

Design of freeform geometries in a MEMS accelerometer with a mechanical motion preamplifier based on a genetic algorithm.

Microsystems & nanoengineering

Wang C, Song X, Fang W, Chen F, Zeimpekis I, Wang Y, Quan A, Bai J, Liu H, Schropfer G, Welham C, Kraft M.
PMID: 34567713
Microsyst Nanoeng. 2020 Nov 30;6:104. doi: 10.1038/s41378-020-00214-1. eCollection 2020.

This paper describes a novel, semiautomated design methodology based on a genetic algorithm (GA) using freeform geometries for microelectromechanical systems (MEMS) devices. The proposed method can design MEMS devices comprising freeform geometries and optimize such MEMS devices to provide...

Correction: An International Consensus Definition of the Wish to Hasten Death and Its Related Factors.

PloS one

Balaguer A, Monforte-Royo C, Porta-Sales J, Alonso-Babarro A, Altisent R, Aradilla-Herrero A, Bellido-Pérez M, Breitbart W, Centeno C, Cuervo MA, Deliens L, Frerich G, Gastmans C, Lichtenfeld S, Limonero JT, Maier MA, Materstvedt LJ, Nabal M, Rodin G, Rosenfeld B, Schroepfer T, Tomás-Sábado J, Trelis J, Villavicencio-Chávez C, Voltz R.
PMID: 29698520
PLoS One. 2018 Apr 26;13(4):e0196754. doi: 10.1371/journal.pone.0196754. eCollection 2018.

[This corrects the article DOI: 10.1371/journal.pone.0146184.].

Gas-Phase Fluorination on PLA Improves Cell Adhesion and Spreading.

ACS omega

Schroepfer M, Junghans F, Voigt D, Meyer M, Breier A, Schulze-Tanzil G, Prade I.
PMID: 32201842
ACS Omega. 2020 Mar 05;5(10):5498-5507. doi: 10.1021/acsomega.0c00126. eCollection 2020 Mar 17.

For the regeneration or creation of functional tissues, biodegradable biomaterials including polylactic acid (PLA) are widely preferred. Modifications of the material surface are quite common to improve cell-material interactions and thereby support the biological outcome. Typical approaches include a...

Sex-Dependent Ketamine Addiction-Like Behavior Profile Following Exposure to Chronic Mild Stress.

Chronic stress (Thousand Oaks, Calif.)

Wright KN, Hagarty DP, Strong CE, Schoepfer KJ, Kabbaj M.
PMID: 31187076
Chronic Stress (Thousand Oaks). 2019 Jan-Dec;3. doi: 10.1177/2470547019832613. Epub 2019 Feb 27.

BACKGROUND: Ketamine has rapid antidepressant effects and shows great promise as a novel treatment for depression, but its limitations including its abuse potential are poorly understood. Given that the prevalence of depression is twice as high in women as...

Showing 1 to 6 of 6 entries