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Showing 1 to 12 of 26 entries
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Implementation and assessment methodologies of teachers' training courses for STEM activities

K-12 STEM training

Cesaretti L, Scaradozzi D, Screpanti L.
GSID: MxhN7L6eAC4J
D Scaradozzi, L Screpanti, L Cesaretti, M Storti… - Technology, Knowledge …, 2019 - Springer

… territoriali (schools which host training courses for a particular … This paper describes a training course for in-service teachers … While the motivation to realise this kind of training course …

An educational robotics activity to promote gender equality in STEM education

STEM education program evaluation

Cesaretti L, Screpanti L.
GSID: YGHHOKw-XiAJ
L Screpanti, L Cesaretti, L Marchetti… - ICICTE 2018 …, 2018 - researchgate.net

In the future boys and girls will be employed in, and maybe create, new jobs connected with technology. We present a project whose aim was to raise interest in STEM education in K12 students and, in particular, to address...

Correction to: Implementation and assessment methodologies of teachers' training courses for STEM activities

Research training stem

Cesaretti L, Scaradozzi D, Screpanti L.
GSID: NZy_n-s4PUwJ
D Scaradozzi, L Screpanti, L Cesaretti… - Technology …, 2019 - search.proquest.com

… and Assessment Methodologies of Teachers’ Training Courses for STEM Activities … Methodologies of Teachers’ Training Courses for STEM Activities D. Scaradozzi1,2 · L. Screpanti1 · …

Comparison of visible imaging, thermography and spectrometry methods to evaluate the effect of .

Plant methods

Joalland S, Screpanti C, Liebisch F, Varella HV, Gaume A, Walter A.
PMID: 28924448
Plant Methods. 2017 Sep 13;13:73. doi: 10.1186/s13007-017-0223-1. eCollection 2017.

BACKGROUND: Phenotyping technologies are expected to provide predictive power for a range of applications in plant and crop sciences. Here, we use the disease pressure of Beet Cyst Nematodes (BCN) on sugar beet as an illustrative example to test...

Broadening phenotype of adenylosuccinate lyase deficiency: A novel clinical pattern resembling neuronal ceroid lipofuscinosis.

Molecular genetics and metabolism reports

Mastrangelo M, Alfonsi C, Screpanti I, Masuelli L, Tavazzi B, Mei D, Giannotti F, Guerrini R, Leuzzi V.
PMID: 31467849
Mol Genet Metab Rep. 2019 Aug 21;21:100502. doi: 10.1016/j.ymgmr.2019.100502. eCollection 2019 Dec.

We describe a 7-year-old boy presenting with a developmental encephalopathy, severe epilepsy, retinopathy with salt and pepper fundus, and ultrastructural skin alterations resembling a neuronal ceroid lipofuscinosis. Whole exome-sequencing detected biallelic variants in the

Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer.

Frontiers in genetics

Pelullo M, Zema S, Nardozza F, Checquolo S, Screpanti I, Bellavia D.
PMID: 31552081
Front Genet. 2019 Aug 21;10:711. doi: 10.3389/fgene.2019.00711. eCollection 2019.

Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased risk of developing several malignancies. The biological and pathogenic importance of Hh signaling emphasizes the need to control its action tightly, both physiologically and therapeutically. Evidence of...

Targeting Notch to Maximize Chemotherapeutic Benefits: Rationale, Advanced Strategies, and Future Perspectives.

Cancers

Zhdanovskaya N, Firrincieli M, Lazzari S, Pace E, Scribani Rossi P, Felli MP, Talora C, Screpanti I, Palermo R.
PMID: 34680255
Cancers (Basel). 2021 Oct 12;13(20). doi: 10.3390/cancers13205106.

Notch signaling guides cell fate decisions by affecting proliferation, apoptosis, stem cell self-renewal, and differentiation depending on cell and tissue context. Given its multifaceted function during tissue development, both overactivation and loss of Notch signaling have been linked to...

Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.

Oncogenesis

Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, Pelullo M, Palermo R, Canettieri G, Talora C, d'Amati G, Bellavia D, Screpanti I, Checquolo S.
PMID: 33071287
Oncogenesis. 2020 Oct 18;9(10):93. doi: 10.1038/s41389-020-00279-7.

Unfolded protein response (UPR) is a conserved adaptive response that tries to restore protein homeostasis after endoplasmic reticulum (ER) stress. Recent studies highlighted the role of UPR in acute leukemias and UPR targeting has been suggested as a therapeutic...

Notch Signaling Activation as a Hallmark for Triple-Negative Breast Cancer Subtype.

Journal of oncology

Giuli MV, Giuliani E, Screpanti I, Bellavia D, Checquolo S.
PMID: 31379945
J Oncol. 2019 Jul 11;2019:8707053. doi: 10.1155/2019/8707053. eCollection 2019.

Triple-negative breast cancer (TNBC) is a subgroup of 15%-20% of diagnosed breast cancer patients. It is generally considered to be the most difficult breast cancer subtype to deal with, due to the lack of estrogen receptor (ER), progesterone receptor...

NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells.

Frontiers in oncology

Di Ianni M, Baldoni S, Del Papa B, Aureli P, Dorillo E, De Falco F, Albi E, Varasano E, Di Tommaso A, Giancola R, Accorsi P, Rotta G, Rompietti C, Silva Barcelos EC, Campese AF, Di Bartolomeo P, Screpanti I, Rosati E, Falzetti F, Sportoletti P.
PMID: 29732315
Front Oncol. 2018 Apr 20;8:105. doi: 10.3389/fonc.2018.00105. eCollection 2018.

To investigate chronic lymphocytic leukemia (CLL)-initiating cells, we assessed

Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells.

Stem cells international

Ceccarelli S, Megiorni F, Bellavia D, Marchese C, Screpanti I, Checquolo S.
PMID: 30723507
Stem Cells Int. 2019 Jan 06;2019:6264931. doi: 10.1155/2019/6264931. eCollection 2019.

Notch signaling is frequently activated in ovarian cancer (OC) and contributes to the proliferation and survival of cultured OC cells as well as to tumor formation and angiogenesis in xenograft models. Several studies demonstrate that Notch3 expression renders cancer...

MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs.

Stem cells international

Catanzaro G, Besharat ZM, Garg N, Ronci M, Pieroni L, Miele E, Mastronuzzi A, Carai A, Alfano V, Po A, Screpanti I, Locatelli F, Urbani A, Ferretti E.
PMID: 26880947
Stem Cells Int. 2016;2016:2683042. doi: 10.1155/2016/2683042. Epub 2016 Jan 06.

Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers. Among them, stem-like cells (hMB-SLCs) represent a fraction of the tumor cell population with the potential...

Showing 1 to 12 of 26 entries