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Showing 1 to 12 of 19 entries
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Chromosome studies in Chiropotes satanas utahicki hershkovitz, 1985 (cebidae, platyrrhini): A comparison with Chiropotes satanas chiropotes.

American journal of primatology

Seuánez HN, Alves G, Lima MMC, Barros RS, Barros CML, Muniz JAPC.
PMID: 31941212
Am J Primatol. 1992;28(3):213-222. doi: 10.1002/ajp.1350280306.

Karyological characterizations of C. s. utahicki (2n = 54) and C. s. chiropotes (2n = 54) showed that these two subspecies are chromosomally very similar. In a single, isolated specimen of C s. utahicki, however, a derived, biarmed, chromosome...

Transcriptome of the Southern Muriqui .

Frontiers in genetics

Moreira DA, Lamarca AP, Soares RF, Coelho AMA, Furtado C, Scherer NM, Moreira MAM, Seuánez HN, Boroni M.
PMID: 32849820
Front Genet. 2020 Jul 31;11:831. doi: 10.3389/fgene.2020.00831. eCollection 2020.

The southern muriqui (

Mutations, Differential Gene Expression, and Chimeric Transcripts in Esophageal Squamous Cell Carcinoma Show High Heterogeneity.

Translational oncology

Souza-Santos PT, Soares Lima SC, Nicolau-Neto P, Boroni M, Meireles Da Costa N, Brewer L, Menezes AN, Furtado C, Moreira MAM, Seuanez HN, de Almeida Simão T, Ribeiro Pinto LF.
PMID: 30172240
Transl Oncol. 2018 Dec;11(6):1283-1291. doi: 10.1016/j.tranon.2018.08.002. Epub 2018 Aug 29.

Esophageal squamous cell carcinoma (ESCC) is a frequent and lethal neoplasia. As recent advances in targeted therapy have not improved ESCC prognosis, characterization of molecular alterations associated to this tumor is of foremost relevance. In this study, we analyze,...

Detailed analysis of X chromosome inactivation in a 49,XXXXX pentasomy.

Molecular cytogenetics

Moraes LM, Cardoso LC, Moura VL, Moreira MA, Menezes AN, Llerena JC, Seuánez HN.
PMID: 19811657
Mol Cytogenet. 2009 Oct 07;2:20. doi: 10.1186/1755-8166-2-20.

BACKGROUND: Pentasomy X (49,XXXXX) has been associated with a severe clinical condition, presumably resulting from failure or disruption of X chromosome inactivation. Here we report that some human X chromosomes from a patient with 49,XXXXX pentasomy were functionally active...

Family-based genome-wide association study in Patagonia confirms the association of the DMD locus and cleft lip and palate.

European journal of oral sciences

Fonseca RF, de Carvalho FM, Poletta FA, Montaner D, Dopazo J, Mereb JC, Moreira MAM, Seuanez HN, Vieira AR, Castilla EE, Orioli IM.
PMID: 26331285
Eur J Oral Sci. 2015 Oct;123(5):381-384. doi: 10.1111/eos.12212. Epub 2015 Sep 01.

The etiology of cleft lip with or without cleft palate (CL±P) is complex and heterogeneous, and multiple genetic and environmental factors are involved. Some candidate genes reported to be associated with oral clefts are located on the X chromosome....

Molecular analysis of holoprosencephaly in South America.

Genetics and molecular biology

Savastano CP, El-Jaick KB, Costa-Lima MA, Abath CM, Bianca S, Cavalcanti DP, Félix TM, Scarano G, Llerena JC, Vargas FR, Moreira MÂ, Seuánez HN, Castilla EE, Orioli IM.
PMID: 24764759
Genet Mol Biol. 2014 Mar;37(1):250-62. doi: 10.1590/s1415-47572014000200011.

Holoprosencephaly (HPE) is a spectrum of brain and facial malformations primarily reflecting genetic factors, such as chromosomal abnormalities and gene mutations. Here, we present a clinical and molecular analysis of 195 probands with HPE or microforms; approximately 72% of...

Chromosome studies of Cebus apella: The standard karyotype of Cebus apella paraguayanus, Fischer, 1829.

American journal of primatology

Matayoshi T, Howlin E, Nasazzi N, Nagle C, Gadow E, Seuánez HN.
PMID: 31979493
Am J Primatol. 1986;10(2):185-193. doi: 10.1002/ajp.1350100208.

Chromosome studies were performed on 40 specimens identified as Cebus apella paraguayanus, Fischer, 1829, which had been wild-caught in Santa Catalina (Republic of Paraguay). Elongated chromosome spreads obtained from lymphocyte cultures were sequentially stained with different techniques, and a...

Genetic characterization of parental cell lines and biochemical analysis of somatic cell hybrids between mouse (RAG) cells and fibroblasts of Ateles paniscus chamek (primates, platyrrhini).

American journal of primatology

Seuánez HN, Alves G, O'brien SJ.
PMID: 31937010
Am J Primatol. 1993;30(3):181-194. doi: 10.1002/ajp.1350300304.

Mouse (RAG) cells, (deficient in hypoxanthine-phosphoribosyl-transferase), and Ateles paniscus chamek primary fibroblasts were used in fusion experiments to generate somatic cell hybrids. Both parental cell lines were genetically characterized by karyological and biochemical analyses with 27 isozyme systems. These...

The Brazilian Hereditary Cancer Network: historical aspects and challenges for clinical cancer genetics in the public health care system in Brazil.

Genetics and molecular biology

Ashton-Prolla P, Seuanez HN.
PMID: 27275665
Genet Mol Biol. 2016 Jun 03;39(2):163-5. doi: 10.1590/1678-4685-GMB-2014-0373.

No abstract available.

Esophageal squamous cell carcinoma transcriptome reveals the effect of .

Oncotarget

Nicolau-Neto P, Da Costa NM, de Souza Santos PT, Gonzaga IM, Ferreira MA, Guaraldi S, Moreira MA, Seuánez HN, Brewer L, Bergmann A, Boroni M, Mencalha AL, Kruel CDP, Lima SCS, Esposito D, Simão TA, Pinto LFR.
PMID: 29682174
Oncotarget. 2018 Mar 30;9(24):16634-16647. doi: 10.18632/oncotarget.24621. eCollection 2018 Mar 30.

Esophageal squamous cell carcinoma (ESCC) presents poor prognosis, and patients diagnosed with this tumor currently lack target treatments. Therefore, in order to identify potential targets for ESCC treatment, we carried out a transcriptome analysis with ESCC and paired nonmalignant...

The characterization of two novel neotropical primate papillomaviruses supports the ancient within-species diversity model.

Virus evolution

D'arc M, Moreira FRR, Dias CA, Souza AR, Seuánez HN, Soares MA, Tavares MCH, Santos AFA.
PMID: 32665860
Virus Evol. 2020 Jun 30;6(1):veaa036. doi: 10.1093/ve/veaa036. eCollection 2020 Jan.

Papillomaviruses (PVs) are non-enveloped icosahedral viruses with a circular double-stranded DNA genome of ∼8,000 base pairs (bp). More than 200 different PV types have been identified to date in humans, which are distributed in five genera, with several strains...

DNA fingerprinting in three species of neotropical primates.

American journal of primatology

Rocha M, Muniz JA, Seuánez HN.
PMID: 31918510
Am J Primatol. 1996;40(1):83-93. doi: 10.1002/(SICI)1098-2345(1996)40:1<83::AID-AJP6>3.0.CO;2-X.

DNA fingerprinting allows the simultaneous detection of a large number of hypervariable loci consisting of highly polymorphic tandem repeat units that are extensively dispersed in the genome. With the 33.6 human minisatellite probe, hypervariable fragments were detected, for the...

Showing 1 to 12 of 19 entries