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Minerva anestesiologica

Antonini R, Bianchi GA, Mezzetti MG, Rizzi F, Severgnini P.
PMID: 1795784
Minerva Anestesiol. 1991 Dec;57(12):1523-5.

No abstract available.

Early outcomes of out-of-hospital cardiac arrest after early defibrillation: a 24 months retrospective analysis.

Indian pacing and electrophysiology journal

Terranova P, Valli P, Severgnini B, Dell'Orto S, Enrico Maria G.
PMID: 17031415
Indian Pacing Electrophysiol J. 2006 Oct 01;6(4):194-201.

INTRODUCTION: Cardiovascular disease remains the most common cause of death in the United States and most other Western nations. Among these deaths, sudden, out-of-hospital cardiac arrest claims approximately 1000 lives each day in the United States alone. Most of...

A systematic review and individual patient data meta-analysis on intra-abdominal hypertension in critically ill patients: the wake-up project. World initiative on Abdominal Hypertension Epidemiology, a Unifying Project (WAKE-Up!).

Minerva anestesiologica

Malbrain ML, Chiumello D, Cesana BM, Reintam Blaser A, Starkopf J, Sugrue M, Pelosi P, Severgnini P, Hernandez G, Brienza N, Kirkpatrick AW, Schachtrupp A, Kempchen J, Estenssoro E, Vidal MG, De Laet I, De Keulenaer BL.
PMID: 24603146
Minerva Anestesiol. 2014 Mar;80(3):293-306. Epub 2013 Dec 12.

Intra-abdominal hypertension (IAH), defined as a pathologically increase in intraabdominal pressure, is commonly found in critically ill patients. While IAH has been associated with several abdominal as well as extra-abdominal conditions, few studies have examined the occurrence of IAH...

Detection of clinically relevant immune checkpoint markers by multicolor flow cytometry.

Journal of biological methods

Cunningham RA, Holland M, McWilliams E, Hodi FS, Severgnini M.
PMID: 31453261
J Biol Methods. 2019 Jun 03;6(2):e114. doi: 10.14440/jbm.2019.283. eCollection 2019.

As checkpoint inhibitor immunotherapies gain traction among cancer researchers and clinicians, the need grows for assays that can definitively phenotype patient immune cells. Herein, we present an 8-color flow cytometry panel for lineage and immune checkpoint markers and validate...

A rapid two-step method for isolation of functional primary mouse hepatocytes: cell characterization and asialoglycoprotein receptor based assay development.

Cytotechnology

Severgnini M, Sherman J, Sehgal A, Jayaprakash NK, Aubin J, Wang G, Zhang L, Peng CG, Yucius K, Butler J, Fitzgerald K.
PMID: 22105762
Cytotechnology. 2012 Mar;64(2):187-95. doi: 10.1007/s10616-011-9407-0. Epub 2011 Nov 22.

Primary mouse hepatocytes are an important tool in the biomedical research field for the assessment of hepatocyte function. Several methods for hepatocyte isolation have been published; however, many of these methods require extensive handling and can therefore compromise the...

"Ticking Bomb": The Impact of Climate Change on the Incidence of Lyme Disease.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Dumic I, Severnini E.
PMID: 30473737
Can J Infect Dis Med Microbiol. 2018 Oct 24;2018:5719081. doi: 10.1155/2018/5719081. eCollection 2018.

Lyme disease (LD) is the most common tick-borne disease in North America. It is caused by

Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management.

ESMO open

Vallerio P, Orenti A, Tosi F, Maistrello M, Palazzini M, Cingarlini S, Colombo P, Bertuzzi M, Spina F, Amatu A, Lombardo R, Prata I, Scaglione F, Vighi GD, Severgnini B, Siena S, Giannattasio C, Boracchi P, Sartore-Bianchi A.
PMID: 34920290
ESMO Open. 2021 Dec 14;7(1):100338. doi: 10.1016/j.esmoop.2021.100338. Epub 2021 Dec 14.

BACKGROUND: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study...

Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management.

ESMO open

Vallerio P, Orenti A, Tosi F, Maistrello M, Palazzini M, Cingarlini S, Colombo P, Bertuzzi M, Spina F, Amatu A, Lombardo R, Prata I, Scaglione F, Vighi GD, Severgnini B, Siena S, Giannattasio C, Boracchi P, Sartore-Bianchi A.
PMID: 34920290
ESMO Open. 2021 Dec 14;7(1):100338. doi: 10.1016/j.esmoop.2021.100338. Epub 2021 Dec 14.

BACKGROUND: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study...

Phase II study of pembrolizumab in refractory esophageal cancer with correlates of response and survival.

Journal for immunotherapy of cancer

de Klerk LK, Patel AK, Derks S, Pectasides E, Augustin J, Uduman M, Raman N, Akarca FG, McCleary NJ, Cleary JM, Rubinson DA, Clark JW, Fitzpatrick B, Brais LK, Cavanaugh ME, Rode AJ, Jean MG, Lizotte PH, Nazzaro MJ, Severgnini M, Zheng H, Fuchs CS, Enzinger PC, Bass AJ.
PMID: 34593617
J Immunother Cancer. 2021 Sep;9(9). doi: 10.1136/jitc-2021-002472.

BACKGROUND: Immune checkpoint inhibitors have revolutionized cancer treatment, but the benefits in refractory patients with esophageal cancer have been modest. Predictors of response as well as new targets for novel therapeutic combinations are needed. In this phase 2 clinical...

High biodiversity in a limited mountain area revealed in the traditional production of Historic Rebel cheese by an integrated microbiota-lipidomic approach.

Scientific reports

Turri F, Cremonesi P, Battelli G, Severgnini M, Brasca M, Gandini G, Pizzi F.
PMID: 33990664
Sci Rep. 2021 May 14;11(1):10374. doi: 10.1038/s41598-021-89959-x.

Historic Rebel (HR) cheese is an Italian heritage cheese, produced from raw milk during the summer grazing period in the Alps. The aim of this work was (i) to characterize the cheese microbiota, by 16S rRNA gene amplicons sequencing,...

Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management.

ESMO open

Vallerio P, Orenti A, Tosi F, Maistrello M, Palazzini M, Cingarlini S, Colombo P, Bertuzzi M, Spina F, Amatu A, Lombardo R, Prata I, Scaglione F, Vighi GD, Severgnini B, Siena S, Giannattasio C, Boracchi P, Sartore-Bianchi A.
PMID: 34920290
ESMO Open. 2021 Dec 14;7(1):100338. doi: 10.1016/j.esmoop.2021.100338. Epub 2021 Dec 14.

BACKGROUND: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study...

Bovine Milk Microbiota: Comparison among Three Different DNA Extraction Protocols To Identify a Better Approach for Bacterial Analysis.

Microbiology spectrum

Cremonesi P, Severgnini M, Romanò A, Sala L, Luini M, Castiglioni B.
PMID: 34550002
Microbiol Spectr. 2021 Oct 31;9(2):e0037421. doi: 10.1128/Spectrum.00374-21. Epub 2021 Sep 22.

The bovine udder is colonized by a huge quantity of microorganisms that constitute the intramammary ecosystem, with a specific role in modulating not only udder homeostasis and mastitis susceptibility, but also the quality of the dairy products. However, generating...

Showing 1 to 12 of 72 entries