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Showing 1 to 12 of 15 entries
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A Case of Daptomycin-Induced Acute Cholestatic Hepatic Injury With Fatal Outcomes.

American journal of therapeutics

Gkoufa A, Goutas D, Sakellariou S, Cholongitas E.
PMID: 33852481
Am J Ther. 2021 Apr 07; doi: 10.1097/MJT.0000000000001310. Epub 2021 Apr 07.

No abstract available.

Unraveling the Epigenetic Role and Clinical Impact of Histone Deacetylases in Neoplasia.

Diagnostics (Basel, Switzerland)

Goutas D, Theocharis S, Tsourouflis G.
PMID: 34441281
Diagnostics (Basel). 2021 Jul 26;11(8). doi: 10.3390/diagnostics11081346.

Histone deacetylases (HDACs) have long been implicated in tumorigenesis and tumor progression demonstrating their important participation in neoplasia. Therefore, numerous studies have been performed, highlighting the mechanism of HDACs action in tumor cells and demonstrating the potential role of...

HuR as Therapeutic Target in Cancer: What the Future Holds.

Current medicinal chemistry

Goutas D, Pergaris A, Giaginis C, Theocharis S.
PMID: 34182901
Curr Med Chem. 2021 Jun 28; doi: 10.2174/0929867328666210628143430. Epub 2021 Jun 28.

ELAV-like protein 1, or HuR (human antigen R), is an RNA-binding protein encoded by the ELAVL1 gene in humans. One of its best functions is to stabilize mRNAs in order to regulate gene expression. HuR protein overexpression has undoubtedly...

Oculomotor nerve palsy due to posterior communicating artery aneurysm: Clipping vs coiling.

Neuro-Chirurgie

Nikova AS, Sioutas GS, Sfyrlida K, Tripsianis G, Karanikas M, Birbilis T.
PMID: 33845117
Neurochirurgie. 2021 Apr 15; doi: 10.1016/j.neuchi.2021.03.012. Epub 2021 Apr 15.

OBJECTIVE: Posterior communicating artery aneurysms (PCoAA) usually present with brain hemorrhage, but they might present with oculomotor nerve palsy (ONP) in about one out of five patients. Treatment options include endovascular coiling and surgical clipping. The present analysis aims...

HuR as Therapeutic Target in Cancer: What the Future Holds.

Current medicinal chemistry

Goutas D, Pergaris A, Giaginis C, Theocharis S.
PMID: 34182901
Curr Med Chem. 2022;29(1):56-65. doi: 10.2174/0929867328666210628143430.

ELAV-like protein 1 or HuR (human antigen R) is an RNA-binding protein that in humans is encoded by the ELAVL1 gene, and one of its best functions is to stabilize mRNAs in order to regulate gene expression. HuR protein...

Robot-assisted carotid artery stenting: outcomes, safety, and operational learning curve.

Neurosurgical focus

Abbas R, Al Saiegh F, El Naamani K, Chen CJ, Velagapudi L, Sioutas GS, Weinberg JH, Tjoumakaris S, Gooch MR, Herial NA, Rosenwasser RH, Jabbour P.
PMID: 34973670
Neurosurg Focus. 2022 Jan;52(1):E17. doi: 10.3171/2021.10.FOCUS21504.

OBJECTIVE: Over the past 2 decades, robots have been increasingly used in surgeries to help overcome human limitations and perform precise and accurate tasks. Endovascular robots were pioneered in interventional cardiology, however, the CorPath GRX was recently approved by...

Comparison of conventional and liquid-based cytology using The Paris System for Reporting Urinary Cytology.

Cytopathology : official journal of the British Society for Clinical Cytology

Goutas D, Savvidou K, Vrettou K, Meletis E, Levis P, Constantinides C, Lazaris AC, Mikou P.
PMID: 34289188
Cytopathology. 2021 Nov;32(6):795-801. doi: 10.1111/cyt.13040. Epub 2021 Aug 04.

BACKGROUND: This retrospective study was conducted to compare the conventional cytospin method and ThinPrep liquid-based urinary cytology in diagnosing bladder cancer using The Paris System (TPS) of classification.METHODS: We retrieved files for 2020, at the Cytopathology Department of Laiko...

Oculomotor nerve palsy due to posterior communicating artery aneurysm: Clipping vs coiling.

Neuro-Chirurgie

Nikova AS, Sioutas GS, Sfyrlida K, Tripsianis G, Karanikas M, Birbilis T.
PMID: 33845117
Neurochirurgie. 2022 Jan;68(1):86-93. doi: 10.1016/j.neuchi.2021.03.012. Epub 2021 Apr 15.

OBJECTIVE: Posterior communicating artery aneurysms (PCoAA) usually present with brain hemorrhage, but they might present with oculomotor nerve palsy (ONP) in about one out of five patients. Treatment options include endovascular coiling and surgical clipping. The present analysis aims...

SARS-CoV-2 Molecular Transmission Clusters and Containment Measures in Ten European Regions during the First Pandemic Wave.

Life (Basel, Switzerland)

Bousali M, Dimadi A, Kostaki EG, Tsiodras S, Nikolopoulos GK, Sgouras DN, Magiorkinis G, Papatheodoridis G, Pogka V, Lourida G, Argyraki A, Angelakis E, Sourvinos G, Beloukas A, Paraskevis D, Karamitros T.
PMID: 33803490
Life (Basel). 2021 Mar 09;11(3). doi: 10.3390/life11030219.

BACKGROUND: The spatiotemporal profiling of molecular transmission clusters (MTCs) using viral genomic data can effectively identify transmission networks in order to inform public health actions targeting SARS-CoV-2 spread.METHODS: We used whole genome SARS-CoV-2 sequences derived from ten European regions...

Impact of .

Microorganisms

Kontizas E, Tastsoglou S, Karamitros T, Karayiannis Y, Kollia P, Hatzigeorgiou AG, Sgouras DN.
PMID: 33339161
Microorganisms. 2020 Dec 16;8(12). doi: 10.3390/microorganisms8122007.

No abstract available.

SDH-deficient renal cell carcinoma: A case report associated with a novel germline mutation.

Clinical case reports

Milionis V, Goutas D, Vlachodimitropoulos D, Katsoulas N, Kyriazis ID, Liatsikos EN, Marinakis N, Joanne TS, Lazaris AC, Goutas N.
PMID: 34703596
Clin Case Rep. 2021 Oct 18;9(10):e04605. doi: 10.1002/ccr3.4605. eCollection 2021 Oct.

The highly syndromic nature of succinate dehydrogenase-deficient RCCs constitutes their active surveillance and molecular profiling the alpha and omega.

Divulging the Critical Role of HuR in Pancreatic Cancer as a Therapeutic Target and a Means to Overcome Chemoresistance.

Cancers

Goutas D, Goutas N, Theocharis S.
PMID: 34572861
Cancers (Basel). 2021 Sep 15;13(18). doi: 10.3390/cancers13184634.

Pancreatic cancer is set to become the most lethal and common type of cancer worldwide. This is partly attributed to the mutational burden that affects core signaling pathways and the crosstalk of tumor cells with their surrounding microenvironment, but...

Showing 1 to 12 of 15 entries