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Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges.

Current infectious disease reports

Shankar-Hari M, Rubenfeld GD.
PMID: 27709504
Curr Infect Dis Rep. 2016 Nov;18(11):37. doi: 10.1007/s11908-016-0544-7.

Sepsis is life-threating organ dysfunction due to infection. Incidence of sepsis is increasing and the short-term mortality is improving, generating more sepsis survivors. These sepsis survivors suffer from additional morbidities such as higher risk of readmissions, cardiovascular disease, cognitive...

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Shankar-Hari M, Rubenfeld GD. Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges. Curr Infect Dis Rep. 2016;18(11):37doi: 10.1007/s11908-016-0544-7.
Shankar-Hari, M., & Rubenfeld, G. D. (2016). Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges. Current infectious disease reports, 18(11), 37. https://doi.org/10.1007/s11908-016-0544-7
Shankar-Hari, Manu, and Rubenfeld, Gordon D. "Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges." Current infectious disease reports vol. 18,11 (2016): 37. doi: https://doi.org/10.1007/s11908-016-0544-7
Shankar-Hari M, Rubenfeld GD. Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges. Curr Infect Dis Rep. 2016 Nov;18(11):37. doi: 10.1007/s11908-016-0544-7. PMID: 27709504; PMCID: PMC5052282.
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Association of cardiometabolic microRNAs with COVID-19 severity and mortality.

Cardiovascular research

Gutmann C, Khamina K, Theofilatos K, Diendorfer AB, Burnap SA, Nabeebaccus A, Fish M, McPhail MJW, O'Gallagher K, Schmidt LE, Cassel C, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Roy R, Edgeworth JD, Shah AM, Hayday AC, Traby L, Hackl M, Eichinger S, Shankar-Hari M, Mayr M.
PMID: 34755842
Cardiovasc Res. 2021 Nov 10; doi: 10.1093/cvr/cvab338. Epub 2021 Nov 10.

AIMS: Coronavirus disease 2019 (COVID-19) can lead to multiorgan damage. MicroRNAs (miRNAs) in blood reflect cell activation and tissue injury. We aimed to determine the association of circulating miRNAs with COVID-19 severity and 28-day intensive care unit (ICU) mortality.METHODS...

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Gutmann C, Khamina K, Theofilatos K, et al. Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovasc Res. 2021;doi: 10.1093/cvr/cvab338.
Gutmann, C., Khamina, K., Theofilatos, K., Diendorfer, A. B., Burnap, S. A., Nabeebaccus, A., Fish, M., McPhail, M. J. W., O'Gallagher, K., Schmidt, L. E., Cassel, C., Auzinger, G., Napoli, S., Mujib, S. F., Trovato, F., Sanderson, B., Merrick, B., Roy, R., Edgeworth, J. D., Shah, A. M., Hayday, A. C., Traby, L., Hackl, M., Eichinger, S., Shankar-Hari, M., & Mayr, M. (2021). Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovascular research, . https://doi.org/10.1093/cvr/cvab338
Gutmann, Clemens, et al. "Association of cardiometabolic microRNAs with COVID-19 severity and mortality." Cardiovascular research vol. (2021). doi: https://doi.org/10.1093/cvr/cvab338
Gutmann C, Khamina K, Theofilatos K, Diendorfer AB, Burnap SA, Nabeebaccus A, Fish M, McPhail MJW, O'Gallagher K, Schmidt LE, Cassel C, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Roy R, Edgeworth JD, Shah AM, Hayday AC, Traby L, Hackl M, Eichinger S, Shankar-Hari M, Mayr M. Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovasc Res. 2021 Nov 10; doi: 10.1093/cvr/cvab338. Epub 2021 Nov 10. PMID: 34755842.
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Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Bangalore H, Carter MJ, Parmar K, Austin C, Shankar-Hari M, Hunt BJ, Tibby SM.
PMID: 33950888
Pediatr Crit Care Med. 2021 Nov 01;22(11):e571-e581. doi: 10.1097/PCC.0000000000002746.

OBJECTIVES: Cardiopulmonary bypass surgery is complicated by metabolic acidosis, microvascular dysfunction, and capillary leak. The glycocalyx-a layer of proteins and sugars lining the vascular endothelium-is degraded during cardiopulmonary bypass. We aimed to describe the kinetics of glycocalyx degradation during...

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Bangalore H, Carter MJ, Parmar K, et al. Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery. Pediatr Crit Care Med. 2021;22(11):e571-e581doi: 10.1097/PCC.0000000000002746.
Bangalore, H., Carter, M. J., Parmar, K., Austin, C., Shankar-Hari, M., Hunt, B. J., & Tibby, S. M. (2021). Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22(11), e571-e581. https://doi.org/10.1097/PCC.0000000000002746
Bangalore, Harish, et al. "Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies vol. 22,11 (2021): e571-e581. doi: https://doi.org/10.1097/PCC.0000000000002746
Bangalore H, Carter MJ, Parmar K, Austin C, Shankar-Hari M, Hunt BJ, Tibby SM. Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery. Pediatr Crit Care Med. 2021 Nov 01;22(11):e571-e581. doi: 10.1097/PCC.0000000000002746. PMID: 33950888.
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Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike.

bioRxiv : the preprint server for biology

Graham C, Seow J, Huettner I, Khan H, Kouphou N, Acors S, Winstone H, Pickering S, Pedro Galao R, Jose Lista M, Jimenez-Guardeno JM, Laing AG, Wu Y, Joseph M, Muir L, Ng WM, Duyvesteyn HME, Zhao Y, Bowden TA, Shankar-Hari M, Rosa A, Cherepanov P, McCoy LE, Hayday AC, Neil SJD, Malim MH, Doores KJ.
PMID: 33564766
bioRxiv. 2021 Feb 03; doi: 10.1101/2021.02.03.429355.

The interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the ACE2 receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing antibodies and several neutralizing epitopes on RBD have been molecularly...

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Graham C, Seow J, Huettner I, et al. Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike. bioRxiv. 2021;doi: 10.1101/2021.02.03.429355.
Graham, C., Seow, J., Huettner, I., Khan, H., Kouphou, N., Acors, S., Winstone, H., Pickering, S., Pedro Galao, R., Jose Lista, M., Jimenez-Guardeno, J. M., Laing, A. G., Wu, Y., Joseph, M., Muir, L., Ng, W. M., Duyvesteyn, H. M. E., Zhao, Y., Bowden, T. A., Shankar-Hari, M., Rosa, A., Cherepanov, P., McCoy, L. E., Hayday, A. C., Neil, S. J. D., Malim, M. H., & Doores, K. J. (2021). Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2021.02.03.429355
Graham, Carl, et al. "Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike." bioRxiv : the preprint server for biology vol. (2021). doi: https://doi.org/10.1101/2021.02.03.429355
Graham C, Seow J, Huettner I, Khan H, Kouphou N, Acors S, Winstone H, Pickering S, Pedro Galao R, Jose Lista M, Jimenez-Guardeno JM, Laing AG, Wu Y, Joseph M, Muir L, Ng WM, Duyvesteyn HME, Zhao Y, Bowden TA, Shankar-Hari M, Rosa A, Cherepanov P, McCoy LE, Hayday AC, Neil SJD, Malim MH, Doores KJ. Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike. bioRxiv. 2021 Feb 03; doi: 10.1101/2021.02.03.429355. PMID: 33564766; PMCID: PMC7872354.
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Towards an ecological definition of sepsis: a viewpoint.

Intensive care medicine experimental

Bauer M, Shankar-Hari M, Thomas-Rüddel DO, Wetzker R.
PMID: 34964952
Intensive Care Med Exp. 2021 Dec 29;9(1):63. doi: 10.1186/s40635-021-00427-2.

In critically ill patients with sepsis, there is a grave lack of effective treatment options to address the illness-defining inappropriate host response. Currently, treatment is limited to source control and supportive care, albeit with imminent approval of immune modulating...

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Bauer M, Shankar-Hari M, Thomas-Rüddel DO, et al. Towards an ecological definition of sepsis: a viewpoint. Intensive Care Med Exp. 2021;9(1):63doi: 10.1186/s40635-021-00427-2.
Bauer, M., Shankar-Hari, M., Thomas-Rüddel, D. O., & Wetzker, R. (2021). Towards an ecological definition of sepsis: a viewpoint. Intensive care medicine experimental, 9(1), 63. https://doi.org/10.1186/s40635-021-00427-2
Bauer, Michael, et al. "Towards an ecological definition of sepsis: a viewpoint." Intensive care medicine experimental vol. 9,1 (2021): 63. doi: https://doi.org/10.1186/s40635-021-00427-2
Bauer M, Shankar-Hari M, Thomas-Rüddel DO, Wetzker R. Towards an ecological definition of sepsis: a viewpoint. Intensive Care Med Exp. 2021 Dec 29;9(1):63. doi: 10.1186/s40635-021-00427-2. PMID: 34964952.
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Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis.

Nature medicine

Laing AG, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, Muñoz-Ruiz M, McKenzie DR, Hayday TS, Francos-Quijorna I, Kamdar S, Joseph M, Davies D, Davis R, Jennings A, Zlatareva I, Vantourout P, Wu Y, Sofra V, Cano F, Greco M, Theodoridis E, Freedman JD, Gee S, Chan JNE, Ryan S, Bugallo-Blanco E, Peterson P, Kisand K, Haljasmägi L, Chadli L, Moingeon P, Martinez L, Merrick B, Bisnauthsing K, Brooks K, Ibrahim MAA, Mason J, Lopez Gomez F, Babalola K, Abdul-Jawad S, Cason J, Mant C, Seow J, Graham C, Doores KJ, Di Rosa F, Edgeworth J, Shankar-Hari M, Hayday AC.
PMID: 33247289
Nat Med. 2020 Dec;26(12):1951. doi: 10.1038/s41591-020-01186-5.

A Correction to this paper has been published: https://doi.org/10.1038/s41591-020-01186-5.

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Laing AG, Lorenc A, Del Molino Del Barrio I, et al. Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26(12):1951doi: 10.1038/s41591-020-01186-5.
Laing, A. G., Lorenc, A., Del Molino Del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., Kamdar, S., Joseph, M., Davies, D., Davis, R., Jennings, A., Zlatareva, I., Vantourout, P., Wu, Y., Sofra, V., Cano, F., Greco, M., Theodoridis, E., Freedman, J. D., Gee, S., Chan, J. N. E., Ryan, S., Bugallo-Blanco, E., Peterson, P., Kisand, K., Haljasmägi, L., Chadli, L., Moingeon, P., Martinez, L., Merrick, B., Bisnauthsing, K., Brooks, K., Ibrahim, M. A. A., Mason, J., Lopez Gomez, F., Babalola, K., Abdul-Jawad, S., Cason, J., Mant, C., Seow, J., Graham, C., Doores, K. J., Di Rosa, F., Edgeworth, J., Shankar-Hari, M., & Hayday, A. C. (2020). Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis. Nature medicine, 26(12), 1951. https://doi.org/10.1038/s41591-020-01186-5
Laing, Adam G, et al. "Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis." Nature medicine vol. 26,12 (2020): 1951. doi: https://doi.org/10.1038/s41591-020-01186-5
Laing AG, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, Muñoz-Ruiz M, McKenzie DR, Hayday TS, Francos-Quijorna I, Kamdar S, Joseph M, Davies D, Davis R, Jennings A, Zlatareva I, Vantourout P, Wu Y, Sofra V, Cano F, Greco M, Theodoridis E, Freedman JD, Gee S, Chan JNE, Ryan S, Bugallo-Blanco E, Peterson P, Kisand K, Haljasmägi L, Chadli L, Moingeon P, Martinez L, Merrick B, Bisnauthsing K, Brooks K, Ibrahim MAA, Mason J, Lopez Gomez F, Babalola K, Abdul-Jawad S, Cason J, Mant C, Seow J, Graham C, Doores KJ, Di Rosa F, Edgeworth J, Shankar-Hari M, Hayday AC. Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020 Dec;26(12):1951. doi: 10.1038/s41591-020-01186-5. PMID: 33247289; PMCID: PMC7694581.
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Correction to: COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland.

Intensive care medicine

Richards-Belle A, Orzechowska I, Gould DW, Thomas K, Doidge JC, Mouncey PR, Christian MD, Shankar-Hari M, Harrison DA, Rowan KM.
PMID: 34061211
Intensive Care Med. 2021 Jun;47(6):731-732. doi: 10.1007/s00134-021-06413-2.

No abstract available.

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Richards-Belle A, Orzechowska I, Gould DW, et al. Correction to: COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland. Intensive Care Med. 2021;47(6):731-732doi: 10.1007/s00134-021-06413-2.
Richards-Belle, A., Orzechowska, I., Gould, D. W., Thomas, K., Doidge, J. C., Mouncey, P. R., Christian, M. D., Shankar-Hari, M., Harrison, D. A., Rowan, K. M. (2021). Correction to: COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland. Intensive care medicine, 47(6), 731-732. https://doi.org/10.1007/s00134-021-06413-2
Richards-Belle, Alvin, et al. "Correction to: COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland." Intensive care medicine vol. 47,6 (2021): 731-732. doi: https://doi.org/10.1007/s00134-021-06413-2
Richards-Belle A, Orzechowska I, Gould DW, Thomas K, Doidge JC, Mouncey PR, Christian MD, Shankar-Hari M, Harrison DA, Rowan KM. Correction to: COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland. Intensive Care Med. 2021 Jun;47(6):731-732. doi: 10.1007/s00134-021-06413-2. PMID: 34061211; PMCID: PMC8167301.
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Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections.

medRxiv : the preprint server for health sciences

Dupont L, Snell LB, Graham C, Seow J, Merrick B, Lechmere T, Hallett SR, Charalampous T, Alcolea-Medina A, Huettner I, Maguire TJA, Acors S, Almeida N, Cox D, Dickenson RE, Galao RP, Jimenez-Guardeño JM, Kouphou N, Lista MJ, Pickering S, Ortega-Prieto AM, Wilson H, Winstone H, Fairhead C, Su J, Nebbia G, Batra R, Neil S, Shankar-Hari M, Edgeworth JD, Malim MH, Doores KJ.
PMID: 34127977
medRxiv. 2021 Jun 08; doi: 10.1101/2021.06.07.21258351.

As SARS-CoV-2 variants continue to emerge globally, a major challenge for COVID-19 vaccination is the generation of a durable antibody response with cross-neutralizing activity against both current and newly emerging viral variants. Cross-neutralizing activity against major variants of concern...

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Dupont L, Snell LB, Graham C, et al. Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections. medRxiv. 2021;doi: 10.1101/2021.06.07.21258351.
Dupont, L., Snell, L. B., Graham, C., Seow, J., Merrick, B., Lechmere, T., Hallett, S. R., Charalampous, T., Alcolea-Medina, A., Huettner, I., Maguire, T. J. A., Acors, S., Almeida, N., Cox, D., Dickenson, R. E., Galao, R. P., Jimenez-Guardeño, J. M., Kouphou, N., Lista, M. J., Pickering, S., Ortega-Prieto, A. M., Wilson, H., Winstone, H., Fairhead, C., Su, J., Nebbia, G., Batra, R., Neil, S., Shankar-Hari, M., Edgeworth, J. D., Malim, M. H., & Doores, K. J. (2021). Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2021.06.07.21258351
Dupont, Liane, et al. "Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2021.06.07.21258351
Dupont L, Snell LB, Graham C, Seow J, Merrick B, Lechmere T, Hallett SR, Charalampous T, Alcolea-Medina A, Huettner I, Maguire TJA, Acors S, Almeida N, Cox D, Dickenson RE, Galao RP, Jimenez-Guardeño JM, Kouphou N, Lista MJ, Pickering S, Ortega-Prieto AM, Wilson H, Winstone H, Fairhead C, Su J, Nebbia G, Batra R, Neil S, Shankar-Hari M, Edgeworth JD, Malim MH, Doores KJ. Antibody longevity and cross-neutralizing activity following SARS-CoV-2 wave 1 and B.1.1.7 infections. medRxiv. 2021 Jun 08; doi: 10.1101/2021.06.07.21258351. PMID: 34127977; PMCID: PMC8202432.
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Association of cardiometabolic microRNAs with COVID-19 severity and mortality.

Cardiovascular research

Gutmann C, Khamina K, Theofilatos K, Diendorfer AB, Burnap SA, Nabeebaccus A, Fish M, McPhail MJW, O'Gallagher K, Schmidt LE, Cassel C, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Roy R, Edgeworth JD, Shah AM, Hayday AC, Traby L, Hackl M, Eichinger S, Shankar-Hari M, Mayr M.
PMID: 34755842
Cardiovasc Res. 2021 Nov 10; doi: 10.1093/cvr/cvab338. Epub 2021 Nov 10.

AIMS: Coronavirus disease 2019 (COVID-19) can lead to multiorgan damage. MicroRNAs (miRNAs) in blood reflect cell activation and tissue injury. We aimed to determine the association of circulating miRNAs with COVID-19 severity and 28-day intensive care unit (ICU) mortality.METHODS...

Cite
Gutmann C, Khamina K, Theofilatos K, et al. Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovasc Res. 2021;doi: 10.1093/cvr/cvab338.
Gutmann, C., Khamina, K., Theofilatos, K., Diendorfer, A. B., Burnap, S. A., Nabeebaccus, A., Fish, M., McPhail, M. J. W., O'Gallagher, K., Schmidt, L. E., Cassel, C., Auzinger, G., Napoli, S., Mujib, S. F., Trovato, F., Sanderson, B., Merrick, B., Roy, R., Edgeworth, J. D., Shah, A. M., Hayday, A. C., Traby, L., Hackl, M., Eichinger, S., Shankar-Hari, M., & Mayr, M. (2021). Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovascular research, . https://doi.org/10.1093/cvr/cvab338
Gutmann, Clemens, et al. "Association of cardiometabolic microRNAs with COVID-19 severity and mortality." Cardiovascular research vol. (2021). doi: https://doi.org/10.1093/cvr/cvab338
Gutmann C, Khamina K, Theofilatos K, Diendorfer AB, Burnap SA, Nabeebaccus A, Fish M, McPhail MJW, O'Gallagher K, Schmidt LE, Cassel C, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Roy R, Edgeworth JD, Shah AM, Hayday AC, Traby L, Hackl M, Eichinger S, Shankar-Hari M, Mayr M. Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovasc Res. 2021 Nov 10; doi: 10.1093/cvr/cvab338. Epub 2021 Nov 10. PMID: 34755842; PMCID: PMC8689968.
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ARDS subphenotypes: searching for Rorschach among the roentgenograms?.

Thorax

Conway Morris A, Kohler K, Shankar-Hari M.
PMID: 34253680
Thorax. 2021 Jul 12; doi: 10.1136/thoraxjnl-2021-217428. Epub 2021 Jul 12.

No abstract available.

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Conway Morris A, Kohler K, Shankar-Hari M. ARDS subphenotypes: searching for Rorschach among the roentgenograms?. Thorax. 2021;doi: 10.1136/thoraxjnl-2021-217428.
Conway Morris, A., Kohler, K., & Shankar-Hari, M. (2021). ARDS subphenotypes: searching for Rorschach among the roentgenograms?. Thorax, . https://doi.org/10.1136/thoraxjnl-2021-217428
Conway Morris, Andrew, et al. "ARDS subphenotypes: searching for Rorschach among the roentgenograms?." Thorax vol. (2021). doi: https://doi.org/10.1136/thoraxjnl-2021-217428
Conway Morris A, Kohler K, Shankar-Hari M. ARDS subphenotypes: searching for Rorschach among the roentgenograms?. Thorax. 2021 Jul 12; doi: 10.1136/thoraxjnl-2021-217428. Epub 2021 Jul 12. PMID: 34253680.
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Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma.

JRSM open

Shepherd SJ, Wong D, Mahadeva U, Goldsmith D, Shankar-Hari M, Ostermann M.
PMID: 27186378
JRSM Open. 2016 May 03;7(5):2054270415608119. doi: 10.1177/2054270415608119. eCollection 2016 May.

Adult T-cell leukaemia-lymphoma is a rare haematological malignancy, which can cause severe hypercalcaemia and metastatic calcification resulting in life-threatening arrhythmias.

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Shepherd SJ, Wong D, Mahadeva U, et al. Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma. JRSM Open. 2016;7(5):2054270415608119doi: 10.1177/2054270415608119.
Shepherd, S. J., Wong, D., Mahadeva, U., Goldsmith, D., Shankar-Hari, M., & Ostermann, M. (2016). Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma. JRSM open, 7(5), 2054270415608119. https://doi.org/10.1177/2054270415608119
Shepherd, Stephen J, et al. "Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma." JRSM open vol. 7,5 (2016): 2054270415608119. doi: https://doi.org/10.1177/2054270415608119
Shepherd SJ, Wong D, Mahadeva U, Goldsmith D, Shankar-Hari M, Ostermann M. Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma. JRSM Open. 2016 May 03;7(5):2054270415608119. doi: 10.1177/2054270415608119. eCollection 2016 May. PMID: 27186378; PMCID: PMC4858725.
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Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates.

Annals of intensive care

Culshaw N, Glover G, Whiteley C, Rowland K, Wyncoll D, Jones A, Shankar-Hari M.
PMID: 25593750
Ann Intensive Care. 2014 Nov 25;4:34. doi: 10.1186/s13613-014-0034-8. eCollection 2014.

BACKGROUND: Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to improve outcomes by targeted prevention strategies. The objectives of the...

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Culshaw N, Glover G, Whiteley C, et al. Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates. Ann Intensive Care. 2014;4:34doi: 10.1186/s13613-014-0034-8.
Culshaw, N., Glover, G., Whiteley, C., Rowland, K., Wyncoll, D., Jones, A., & Shankar-Hari, M. (2014). Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates. Annals of intensive care, 434. https://doi.org/10.1186/s13613-014-0034-8
Culshaw, Nick, et al. "Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates." Annals of intensive care vol. 4 (2014): 34. doi: https://doi.org/10.1186/s13613-014-0034-8
Culshaw N, Glover G, Whiteley C, Rowland K, Wyncoll D, Jones A, Shankar-Hari M. Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates. Ann Intensive Care. 2014 Nov 25;4:34. doi: 10.1186/s13613-014-0034-8. eCollection 2014. PMID: 25593750; PMCID: PMC4273689.
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Showing 1 to 12 of 28 entries