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Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications.

Bioinformation

Chiappelli F, Shapshak P, Commins D, Singer E, Minagar A, Oluwadara O, Prolo P, Pellionisz AJ.
PMID: 19052666
Bioinformation. 2008;3(1):47-52. doi: 10.6026/97320630003047. Epub 2008 Oct 07.

Epigenetics studies factors related to the organism and environment that modulate inheritance from generation to generation. Molecular epigenetics examines non-coding DNA (ncdDNA) vs. coding DNA (cdDNA), and pertains to every domain of physiology, including immune and brain function. Molecular...

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Chiappelli F, Shapshak P, Commins D, et al. Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications. Bioinformation. 2008;3(1):47-52doi: 10.6026/97320630003047.
Chiappelli, F., Shapshak, P., Commins, D., Singer, E., Minagar, A., Oluwadara, O., Prolo, P., & Pellionisz, A. J. (2008). Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications. Bioinformation, 3(1), 47-52. https://doi.org/10.6026/97320630003047
Chiappelli, Francesco, et al. "Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications." Bioinformation vol. 3,1 (2008): 47-52. doi: https://doi.org/10.6026/97320630003047
Chiappelli F, Shapshak P, Commins D, Singer E, Minagar A, Oluwadara O, Prolo P, Pellionisz AJ. Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications. Bioinformation. 2008;3(1):47-52. doi: 10.6026/97320630003047. Epub 2008 Oct 07. PMID: 19052666; PMCID: PMC2586137.
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Molecule of the month HIV-1 Tat and miRNA.

Bioinformation

Shapshak P.
PMID: 23275707
Bioinformation. 2012;8(23):1123-4. doi: 10.6026/97320630081123. Epub 2012 Nov 23.

No abstract available.

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Shapshak P. Molecule of the month HIV-1 Tat and miRNA. Bioinformation. 2012;8(23):1123-4doi: 10.6026/97320630081123.
Shapshak, P. (2012). Molecule of the month HIV-1 Tat and miRNA. Bioinformation, 8(23), 1123-4. https://doi.org/10.6026/97320630081123
Shapshak, Paul. "Molecule of the month HIV-1 Tat and miRNA." Bioinformation vol. 8,23 (2012): 1123-4. doi: https://doi.org/10.6026/97320630081123
Shapshak P. Molecule of the month HIV-1 Tat and miRNA. Bioinformation. 2012;8(23):1123-4. doi: 10.6026/97320630081123. Epub 2012 Nov 23. PMID: 23275707; PMCID: PMC3530879.
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Molecule of the month: HIV-1 protein Vpr and miRNA.

Bioinformation

Shapshak P.
PMID: 23275727
Bioinformation. 2012;8(25):1243-4. doi: 10.6026/97320630081243. Epub 2012 Dec 19.

No abstract available.

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Shapshak P. Molecule of the month: HIV-1 protein Vpr and miRNA. Bioinformation. 2012;8(25):1243-4doi: 10.6026/97320630081243.
Shapshak, P. (2012). Molecule of the month: HIV-1 protein Vpr and miRNA. Bioinformation, 8(25), 1243-4. https://doi.org/10.6026/97320630081243
Shapshak, Paul. "Molecule of the month: HIV-1 protein Vpr and miRNA." Bioinformation vol. 8,25 (2012): 1243-4. doi: https://doi.org/10.6026/97320630081243
Shapshak P. Molecule of the month: HIV-1 protein Vpr and miRNA. Bioinformation. 2012;8(25):1243-4. doi: 10.6026/97320630081243. Epub 2012 Dec 19. PMID: 23275727; PMCID: PMC3532007.
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Structural inferences for Cholera toxin mutations in Vibrio cholerae.

Bioinformation

Shamini G, Ravichandran M, Sinnott JT, Somboonwit C, Sidhu HS, Shapshak P, Kangueane P.
PMID: 21464837
Bioinformation. 2011 Mar 02;6(1):1-9. doi: 10.6026/97320630006001.

Cholera is a global disease that has persisted for millennia. The cholera toxin (CT) from Vibrio cholerae is responsible for the clinical symptoms of cholera. This toxin is a hetero-hexamer (AB(5)) complex consisting of a subunit A (CTA) with...

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Shamini G, Ravichandran M, Sinnott JT, et al. Structural inferences for Cholera toxin mutations in Vibrio cholerae. Bioinformation. 2011;6(1):1-9doi: 10.6026/97320630006001.
Shamini, G., Ravichandran, M., Sinnott, J. T., Somboonwit, C., Sidhu, H. S., Shapshak, P., & Kangueane, P. (2011). Structural inferences for Cholera toxin mutations in Vibrio cholerae. Bioinformation, 6(1), 1-9. https://doi.org/10.6026/97320630006001
Shamini, Gunasagaran, et al. "Structural inferences for Cholera toxin mutations in Vibrio cholerae." Bioinformation vol. 6,1 (2011): 1-9. doi: https://doi.org/10.6026/97320630006001
Shamini G, Ravichandran M, Sinnott JT, Somboonwit C, Sidhu HS, Shapshak P, Kangueane P. Structural inferences for Cholera toxin mutations in Vibrio cholerae. Bioinformation. 2011 Mar 02;6(1):1-9. doi: 10.6026/97320630006001. PMID: 21464837; PMCID: PMC3064844.
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A HLA-DRB supertype chart with potential overlapping peptide binding function.

Bioinformation

Mohanapriya A, Nandagond S, Shapshak P, Kangueane U, Kangueane P.
PMID: 20978603
Bioinformation. 2010 Jan 20;4(7):300-9. doi: 10.6026/97320630004300.

HLA-DRB alleles are class II alleles that are associated with CD4+ T-cell immune response. DRB alleles are polymorphic and currently there are about 622 named in the IMGT/HLA sequence database. Each allele binds short peptides with high sensitivity and...

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Mohanapriya A, Nandagond S, Shapshak P, et al. A HLA-DRB supertype chart with potential overlapping peptide binding function. Bioinformation. 2010;4(7):300-9doi: 10.6026/97320630004300.
Mohanapriya, A., Nandagond, S., Shapshak, P., Kangueane, U., & Kangueane, P. (2010). A HLA-DRB supertype chart with potential overlapping peptide binding function. Bioinformation, 4(7), 300-9. https://doi.org/10.6026/97320630004300
Mohanapriya, Arumugam, et al. "A HLA-DRB supertype chart with potential overlapping peptide binding function." Bioinformation vol. 4,7 (2010): 300-9. doi: https://doi.org/10.6026/97320630004300
Mohanapriya A, Nandagond S, Shapshak P, Kangueane U, Kangueane P. A HLA-DRB supertype chart with potential overlapping peptide binding function. Bioinformation. 2010 Jan 20;4(7):300-9. doi: 10.6026/97320630004300. PMID: 20978603; PMCID: PMC2957767.
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Molecule of the month: miRNA and Huntington's disease (HD).

Bioinformation

Shapshak P.
PMID: 23888093
Bioinformation. 2013 Jun 29;9(11):549-50. doi: 10.6026/97320630009549. Print 2013.

No abstract available.

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Shapshak P. Molecule of the month: miRNA and Huntington's disease (HD). Bioinformation. 2013;9(11):549-50doi: 10.6026/97320630009549.
Shapshak, P. (2013). Molecule of the month: miRNA and Huntington's disease (HD). Bioinformation, 9(11), 549-50. https://doi.org/10.6026/97320630009549
Shapshak, Paul. "Molecule of the month: miRNA and Huntington's disease (HD)." Bioinformation vol. 9,11 (2013): 549-50. doi: https://doi.org/10.6026/97320630009549
Shapshak P. Molecule of the month: miRNA and Huntington's disease (HD). Bioinformation. 2013 Jun 29;9(11):549-50. doi: 10.6026/97320630009549. Print 2013. PMID: 23888093; PMCID: PMC3717180.
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Astrobiology - an opposing view.

Bioinformation

Shapshak P.
PMID: 30237680
Bioinformation. 2018 Jun 30;14(6):346-349. doi: 10.6026/97320630014346. eCollection 2018.

The use of quantum computers and Artificial Intelligence (AI) is imperative for use in space exploration and astrobiology investigations. Considerable progress has been made since the commencement of origin of life laboratory and theoretical studies in the mid 20th...

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Shapshak P. Astrobiology - an opposing view. Bioinformation. 2018;14(6):346-349doi: 10.6026/97320630014346.
Shapshak, P. (2018). Astrobiology - an opposing view. Bioinformation, 14(6), 346-349. https://doi.org/10.6026/97320630014346
Shapshak, Paul. "Astrobiology - an opposing view." Bioinformation vol. 14,6 (2018): 346-349. doi: https://doi.org/10.6026/97320630014346
Shapshak P. Astrobiology - an opposing view. Bioinformation. 2018 Jun 30;14(6):346-349. doi: 10.6026/97320630014346. eCollection 2018. PMID: 30237680; PMCID: PMC6137566.
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Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence.

Annals of the New York Academy of Sciences

Mash DC, Kovera CA, Buck BE, Norenberg MD, Shapshak P, Hearn WL, Sanchez-Ramos J.
PMID: 29090804
Ann N Y Acad Sci. 1998 May;844(1):274-292. doi: 10.1111/j.1749-6632.1998.tb08242.x.

The potential for deriving new psychotherapeutic medications from natural sources has led to renewed interest in rain forest plants as a source of lead compounds for the development of antiaddiction medications. Ibogaine is an indole alkaloid found in the...

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Mash DC, Kovera CA, Buck BE, et al. Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence. Ann N Y Acad Sci. 1998;844(1):274-292doi: 10.1111/j.1749-6632.1998.tb08242.x.
Mash, D. C., Kovera, C. A., Buck, B. E., Norenberg, M. D., Shapshak, P., Hearn, W. L., & Sanchez-Ramos, J. (1998). Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence. Annals of the New York Academy of Sciences, 844(1), 274-292. https://doi.org/10.1111/j.1749-6632.1998.tb08242.x
Mash, Deborah C, et al. "Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence." Annals of the New York Academy of Sciences vol. 844,1 (1998): 274-292. doi: https://doi.org/10.1111/j.1749-6632.1998.tb08242.x
Mash DC, Kovera CA, Buck BE, Norenberg MD, Shapshak P, Hearn WL, Sanchez-Ramos J. Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence. Ann N Y Acad Sci. 1998 May;844(1):274-292. doi: 10.1111/j.1749-6632.1998.tb08242.x. PMID: 29090804.
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Artificial Intelligence and brain.

Bioinformation

Shapshak P.
PMID: 29497259
Bioinformation. 2018 Jan 31;14(1):38-41. doi: 10.6026/97320630014038. eCollection 2018.

From the start, Kurt Godel observed that computer and brain paradigms were considered on a par by researchers and that researchers had misunderstood his theorems. He hailed with displeasure that the brain transcends computers. In this brief article, we...

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Shapshak P. Artificial Intelligence and brain. Bioinformation. 2018;14(1):38-41doi: 10.6026/97320630014038.
Shapshak, P. (2018). Artificial Intelligence and brain. Bioinformation, 14(1), 38-41. https://doi.org/10.6026/97320630014038
Shapshak, Paul. "Artificial Intelligence and brain." Bioinformation vol. 14,1 (2018): 38-41. doi: https://doi.org/10.6026/97320630014038
Shapshak P. Artificial Intelligence and brain. Bioinformation. 2018 Jan 31;14(1):38-41. doi: 10.6026/97320630014038. eCollection 2018. PMID: 29497259; PMCID: PMC5818638.
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1,2-Aminofunctionalization Reactions of Pyridino-Alkynes via Carbophilic Activation.

Chemical record (New York, N.Y.)

Paroi B, Sancheti SP, Patil NT.
PMID: 34669247
Chem Rec. 2021 Oct 20; doi: 10.1002/tcr.202100145. Epub 2021 Oct 20.

Transition metal-catalyzed 1,2-difunctionalization reactions of alkynes have emerged as a powerful tool to forge carbon-carbon and carbon-heteroatom bonds for the rapid synthesis of polyfunctionalized molecular scaffolds. In this regard, our group has persistently been developing transition metal-mediated 1,2-aminofunctionalization reactions...

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Paroi B, Sancheti SP, Patil NT. 1,2-Aminofunctionalization Reactions of Pyridino-Alkynes via Carbophilic Activation. Chem Rec. 2021;doi: 10.1002/tcr.202100145.
Paroi, B., Sancheti, S. P., & Patil, N. T. (2021). 1,2-Aminofunctionalization Reactions of Pyridino-Alkynes via Carbophilic Activation. Chemical record (New York, N.Y.), . https://doi.org/10.1002/tcr.202100145
Paroi, Bidisha, et al. "1,2-Aminofunctionalization Reactions of Pyridino-Alkynes via Carbophilic Activation." Chemical record (New York, N.Y.) vol. (2021). doi: https://doi.org/10.1002/tcr.202100145
Paroi B, Sancheti SP, Patil NT. 1,2-Aminofunctionalization Reactions of Pyridino-Alkynes via Carbophilic Activation. Chem Rec. 2021 Oct 20; doi: 10.1002/tcr.202100145. Epub 2021 Oct 20. PMID: 34669247.
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ortho-Oxygenative 1,2-Difunctionalization of Diarylalkynes under Merged Gold/Organophotoredox Relay Catalysis.

Chemistry, an Asian journal

Sancheti SP, Akram MO, Roy R, Bedi V, Kundu S, Patil NT.
PMID: 31589800
Chem Asian J. 2019 Dec 13;14(24):4601-4606. doi: 10.1002/asia.201901275. Epub 2019 Oct 30.

Reported herein is an ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox catalysis to access highly functionalized 2-(2-hydroxyaryl)-2-alkoxy-1-arylethan-1-ones. Detailed mechanistic studies suggested a relay process, initiating with gold-catalyzed hydroalkoxylation of alkynes, to generate enol-ether followed by a key formal [4+2]-cycloaddition...

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Sancheti SP, Akram MO, Roy R, et al. ortho-Oxygenative 1,2-Difunctionalization of Diarylalkynes under Merged Gold/Organophotoredox Relay Catalysis. Chem Asian J. 2019;14(24):4601-4606doi: 10.1002/asia.201901275.
Sancheti, S. P., Akram, M. O., Roy, R., Bedi, V., Kundu, S., & Patil, N. T. (2019). ortho-Oxygenative 1,2-Difunctionalization of Diarylalkynes under Merged Gold/Organophotoredox Relay Catalysis. Chemistry, an Asian journal, 14(24), 4601-4606. https://doi.org/10.1002/asia.201901275
Sancheti, Shashank P, et al. "ortho-Oxygenative 1,2-Difunctionalization of Diarylalkynes under Merged Gold/Organophotoredox Relay Catalysis." Chemistry, an Asian journal vol. 14,24 (2019): 4601-4606. doi: https://doi.org/10.1002/asia.201901275
Sancheti SP, Akram MO, Roy R, Bedi V, Kundu S, Patil NT. ortho-Oxygenative 1,2-Difunctionalization of Diarylalkynes under Merged Gold/Organophotoredox Relay Catalysis. Chem Asian J. 2019 Dec 13;14(24):4601-4606. doi: 10.1002/asia.201901275. Epub 2019 Oct 30. PMID: 31589800.
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Gold(I)-Catalyzed Hydroxy Group Assisted C(sp.

Organic letters

Bagle PN, Mane MV, Sancheti SP, Gade AB, Shaikh SR, Baik MH, Patil NT.
PMID: 30586309
Org Lett. 2019 Jan 04;21(1):335-339. doi: 10.1021/acs.orglett.8b03989. Epub 2018 Dec 26.

A strategy for expedient synthesis of 3-substituted chromones from easily available o-hydroxyarylenaminones and diazo compounds has been developed. Carefully conducted experimental and computational studies led us to propose an uncommon mechanistic pathway involving the hydroxyl group assisted alkylation of...

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Bagle PN, Mane MV, Sancheti SP, et al. Gold(I)-Catalyzed Hydroxy Group Assisted C(sp. Org Lett. 2018;21(1):335-339doi: 10.1021/acs.orglett.8b03989.
Bagle, P. N., Mane, M. V., Sancheti, S. P., Gade, A. B., Shaikh, S. R., Baik, M. H., & Patil, N. T. (2019). Gold(I)-Catalyzed Hydroxy Group Assisted C(sp. Organic letters, 21(1), 335-339. https://doi.org/10.1021/acs.orglett.8b03989
Bagle, Pradip N, et al. "Gold(I)-Catalyzed Hydroxy Group Assisted C(sp." Organic letters vol. 21,1 (2019): 335-339. doi: https://doi.org/10.1021/acs.orglett.8b03989
Bagle PN, Mane MV, Sancheti SP, Gade AB, Shaikh SR, Baik MH, Patil NT. Gold(I)-Catalyzed Hydroxy Group Assisted C(sp. Org Lett. 2019 Jan 04;21(1):335-339. doi: 10.1021/acs.orglett.8b03989. Epub 2018 Dec 26. PMID: 30586309.
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Showing 1 to 12 of 55 entries