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Showing 1 to 12 of 106 entries
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Access to Imidazo[1,2-a]pyridines via Annulation of α-Keto Vinyl Azides and 2-Aminopyridines.

Organic letters

Adiyala PR, Mani GS, Nanubolu JB, Shekar KC, Maurya RA.
PMID: 26308984
Org Lett. 2015 Sep 04;17(17):4308-11. doi: 10.1021/acs.orglett.5b02124. Epub 2015 Aug 26.

A novel strategy for the synthesis of imidazo[1,2-a]pyridines via efficient catalyst/metal-free annulations of α-keto vinyl azides and 2-aminopyridines is described. Several imidazo[1,2-a]pyridines were synthesized from readily available vinyl azides and 2-aminopyridines and obtained in highly pure form by simply...

Facial nerve paralysis: A case report of rare complication in uncontrolled diabetic patient with mucormycosis.

Journal of natural science, biology, and medicine

Shekar V, Sikander J, Rangdhol V, Naidu M.
PMID: 25810669
J Nat Sci Biol Med. 2015 Jan-Jun;6(1):226-8. doi: 10.4103/0976-9668.149195.

Mucormycosis is a rare opportunistic aggressive and fatal infection caused by mucor fungus. Seven types of mucormycosis are identified based on the extension and involvement of the lesion, of which the rhino orbital mucormycosis is most common in the...

A novel echocardiographic imaging technique, intracatheter echocardiography, to guide veno-venous extracorporeal membrane oxygenation cannulae placement in a validated ovine model.

Intensive care medicine experimental

Platts DG, Hilton A, Diab S, McDonald C, Tunbridge M, Chemonges S, Dunster KR, Shekar K, Burstow DJ, Fraser JF.
PMID: 26266903
Intensive Care Med Exp. 2014 Dec;2(1):2. doi: 10.1186/2197-425X-2-2. Epub 2014 Feb 06.

BACKGROUND: Echocardiography plays a fundamental role in cannulae insertion and positioning for extracorporeal membrane oxygenation (ECMO). Optimal access and return cannulae orientation is required to prevent recirculation. The aim of this study was to compare a novel imaging technique,...

Role of cone beam computed tomography and white mineral trioxide aggregate in the successful management of a permanent anterior tooth with open apex.

Journal of international oral health : JIOH

Shekhar V, Arora R, Roy M.
PMID: 25214736
J Int Oral Health. 2014 Jul;6(4):68-72.

Cone beam computed tomography (CBCT) is a recent three-dimensional (3D) radiographic imaging modality used for the accurate diagnosis, management and follow-up of endodontic problems. In tooth with open apex and periapical lesion, the use of new obturation material such...

Optimising drug dosing in patients receiving extracorporeal membrane oxygenation.

Journal of thoracic disease

Cheng V, Abdul-Aziz MH, Roberts JA, Shekar K.
PMID: 29732181
J Thorac Dis. 2018 Mar;10:S629-S641. doi: 10.21037/jtd.2017.09.154.

Optimal pharmacological management during extracorporeal membrane oxygenation (ECMO) involves more than administering drugs to reverse underlying disease. ECMO is a complex therapy that should be administered in a goal-directed manner to achieve therapeutic endpoints that allow reversal of disease...

Use and Cost of a Hypoglossal Nerve Stimulator Device for Obstructive Sleep Apnea Between 2015 and 2018.

JAMA otolaryngology-- head & neck surgery

Rathi VK, Kondamuri NS, Naunheim MR, Gadkaree SK, Metson RB, Scangas GA.
PMID: 31436783
JAMA Otolaryngol Head Neck Surg. 2019 Oct 01;145(10):975-977. doi: 10.1001/jamaoto.2019.2366.

No abstract available.

Ni-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Olefins by Intercepting Heck Intermediates as Imine-Stabilized Transient Metallacycles.

Journal of the American Chemical Society

Shrestha B, Basnet P, Dhungana RK, Kc S, Thapa S, Sears JM, Giri R.
PMID: 28737904
J Am Chem Soc. 2017 Aug 09;139(31):10653-10656. doi: 10.1021/jacs.7b06340. Epub 2017 Jul 26.

We disclose a strategy for Ni-catalyzed dicarbofunctionalization of olefins in styrenes by intercepting Heck C(sp

Predictors of pediatric blunt cerebrovascular injury.

Journal of pediatric surgery

Rossidis AC, Tharakan SJ, Bose SK, Shekdar KV, Nance ML, Blinman TA.
PMID: 29108846
J Pediatr Surg. 2017 Oct 12; doi: 10.1016/j.jpedsurg.2017.10.037. Epub 2017 Oct 12.

BACKGROUND/PURPOSE: Blunt cerebrovascular injury (BCVI) is clinically challenging because these injuries are hard to detect and can have serious neurological consequences, and optimal screening criteria have not been established for children. This study aims to determine risk factors for...

Extubate Before Venovenous Extracorporeal Membranous Oxygenation Decannulation or Decannulate While Remaining on the Ventilator? The EuroELSO 2019 Weaning Survey.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Swol J, Shekar K, Protti A, Tukacs M, Broman LM, Barrett NA, Mueller T, Peek GJ, Buscher H.
PMID: 32701622
ASAIO J. 2021 Apr 01;67(4):e86-e89. doi: 10.1097/MAT.0000000000001237.

No abstract available.

Ni-Catalyzed Regioselective Alkylarylation of Vinylarenes via C(sp.

Journal of the American Chemical Society

Kc S, Dhungana RK, Shrestha B, Thapa S, Khanal N, Basnet P, Lebrun RW, Giri R.
PMID: 30049210
J Am Chem Soc. 2018 Aug 08;140(31):9801-9805. doi: 10.1021/jacs.8b05374. Epub 2018 Jul 30.

We report a Ni-catalyzed regioselective alkylarylation of vinylarenes with alkyl halides and arylzinc reagents to generate 1,1-diarylalkanes. The reaction proceeds well with primary, secondary and tertiary alkyl halides, and electronically diverse arylzinc reagents. Mechanistic investigations by radical probes, competition...

AJNR. American journal of neuroradiology

Subramanian S, Biswas A, Alves CAPF, Sudhakar SV, Shekdar KV, Krishnan P, Shroff M, Taranath A, Arrigoni F, Aldinger KA, Leventer RJ, Dobyns WB, Mankad K.
PMID: 34857515
AJNR Am J Neuroradiol. 2021 Dec 02; doi: 10.3174/ajnr.A7364. Epub 2021 Dec 02.

BACKGROUND AND PURPOSE: Pathogenic variants in the MATERIALS AND METHODS: We performed a retrospective, multicentric review of patients with proved RESULTS: We included 13 patients with CONCLUSIONS: Dysgyria is common in patients with

Is intensive care unit mortality a valid survival outcome measure related to critical illness?.

Anaesthesia, critical care & pain medicine

Laupland KB, Ramanan M, Shekar K, Kirrane M, Clement P, Young P, Edwards F, Bushell R, Tabah A.
PMID: 34902631
Anaesth Crit Care Pain Med. 2021 Dec 10;41(1):100996. doi: 10.1016/j.accpm.2021.100996. Epub 2021 Dec 10.

RATIONALE: Use of death as an outcome of intensive care unit (ICU) admission may be biased by differential discharge decisions.OBJECTIVE: To determine the validity of ICU survival status as an outcome measure of all cause case-fatality.METHODS: A retrospective cohort...

Showing 1 to 12 of 106 entries