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Showing 1 to 12 of 342 entries
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Career development in intensive care: 1.

British journal of nursing (Mark Allen Publishing)

Sheppard A.
PMID: 1446153
Br J Nurs. 1992 Sep 10-23;1(9):467-9. doi: 10.12968/bjon.1992.1.9.467.

Nursing is becoming more specialized and leaner in terms of structure and therefore competition for positions is increasing. It is essential for nurses who are considering a career in intensive care to commence the planning process as early as...

Deletion of Genes From the Mouse Genome Using Cre/loxP Technology.

Methods in molecular biology (Clifton, N.J.)

Hernandez D, Chandan P, Janmohamed A, Phillips IR, Shephard EA.
PMID: 27699674
Methods Mol Biol. 2006;320:307-319. doi: 10.1385/1-59259-998-2:307.

The steps required to delete genes from the mouse genome are illustrated by showing how a cluster of three flavin-containing monooxygenase (Fmo) genes (Fmo1, Fmo2, and Fmo4) were deleted from mouse chromosome 1. Such large deletions are accomplished using...

Expression of Recombinant Flavin-Containing Monooxygenases in a Baculovirus/Insect Cell System.

Methods in molecular biology (Clifton, N.J.)

Janmohamed A, Thaunsukon P, Shephard EA, Phillips IR.
PMID: 27699678
Methods Mol Biol. 2006;320:39-59. doi: 10.1385/1-59259-998-2:39.

The baculovirus/insect cell heterologous expression system provides an important tool for investigating the catalytic activity of individual drug-metabolizing enzymes toward a particular substrate. In this chapter we describe a baculovirus/insect cell system that we have used for the expression...

A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments.

Computational and structural biotechnology journal

Dona AC, Kyriakides M, Scott F, Shephard EA, Varshavi D, Veselkov K, Everett JR.
PMID: 27087910
Comput Struct Biotechnol J. 2016 Mar 09;14:135-53. doi: 10.1016/j.csbj.2016.02.005. eCollection 2016.

Metabonomics/metabolomics is an important science for the understanding of biological systems and the prediction of their behaviour, through the profiling of metabolites. Two technologies are routinely used in order to analyse metabolite profiles in biological fluids: nuclear magnetic resonance...

Evolution in agriculture: the application of evolutionary approaches to the management of biotic interactions in agro-ecosystems.

Evolutionary applications

Thrall PH, Oakeshott JG, Fitt G, Southerton S, Burdon JJ, Sheppard A, Russell RJ, Zalucki M, Heino M, Ford Denison R.
PMID: 25567968
Evol Appl. 2011 Mar;4(2):200-15. doi: 10.1111/j.1752-4571.2010.00179.x.

Anthropogenic impacts increasingly drive ecological and evolutionary processes at many spatio-temporal scales, demanding greater capacity to predict and manage their consequences. This is particularly true for agro-ecosystems, which not only comprise a significant proportion of land use, but which...

Disaggregated N.

Atmospheric environment (Oxford, England : 1994)

Shepherd A, Yan X, Nayak D, Newbold J, Moran D, Dhanoa MS, Goulding K, Smith P, Cardenas LM.
PMID: 26865831
Atmos Environ (1994). 2015 Dec;122:272-281. doi: 10.1016/j.atmosenv.2015.09.054.

China accounts for a third of global nitrogen fertilizer consumption. Under an International Panel on Climate Change (IPCC) Tier 2 assessment, emission factors (EFs) are developed for the major crop types using country-specific data. IPCC advises a separate calculation...

Parliament.

Mental health (London)

Sheppard A.
PMID: 28908858
Ment Health (Lond). 1970;29:45-47.

No abstract available.

MINDING THEIR OWN BUSINESS: MARRIED WOMEN AND CREDIT IN EARLY EIGHTEENTH-CENTURY LONDON.

Transactions of the Royal Historical Society

Shepard A.
PMID: 26633910
Trans R Hist Soc. 2015 Dec;25:53-74. doi: 10.1017/S008044011500002X.

Taking a micro-historical approach, this paper explores the business activities of Elizabeth Carter and Elizabeth Hatchett, two married women who operated together as pawnbrokers in London in the early decades of the eighteenth century. Based on a protracted inheritance...

Utilization of a novel model of food reinforced behavior involving neuropeptide Y, insulin, 2-deoxy-d-glucose and naloxone.

Behavioural pharmacology

O'Hare E, Levine AS, Semotuk MT, Tierney KJ, Shephard RA, Grace MK, Cleary J.
PMID: 11224469
Behav Pharmacol. 1996 Dec;7(8):742-753.

The cyclic-ratio schedule methodology exposes animals to an ascending followed by a descending sequence of ratio values over six consecutive cycles. The response functions, obtained by plotting response rates against reinforcement rates at each schedule value, are argued to...

Recent sea-level contributions of the Antarctic and Greenland ice sheets.

Science (New York, N.Y.)

Shepherd A, Wingham D.
PMID: 17363663
Science. 2007 Mar 16;315(5818):1529-32. doi: 10.1126/science.1136776.

After a century of polar exploration, the past decade of satellite measurements has painted an altogether new picture of how Earth's ice sheets are changing. As global temperatures have risen, so have rates of snowfall, ice melting, and glacier...

Moisture induced solid phase degradation of l-ascorbic acid Part 1: a kinetic study using tristimulus colorimetry and a quantitative HPLC assay.

Talanta

Shephard AB, Nichols SC, Braithwaite A.
PMID: 18967499
Talanta. 1999 Mar;48(3):585-93. doi: 10.1016/s0039-9140(98)00280-x.

l-Ascorbic acid was found to degrade in the solid phase with discoloration under the influence of moisture in proportion to the moisture content. This degradation pattern was different to that in solution and followed zero order kinetics. The exclusion...

Pancreatic pseudocystwith stent placement in the background of narcotic use: a case report.

Cases journal

Offord S, Gumustop B, Shepard A.
PMID: 18840260
Cases J. 2008 Oct 07;1(1):219. doi: 10.1186/1757-1626-1-219.

A 49 year old gentleman presents with recurrent abdominal pain. The patient has a known history of chronic pancreatitis, alcoholism and narcotic addiction. Work-up, including computed tomography (CT) of the abdomen, demonstrated a 5.6 x 5.8 cm fluid collection...

Showing 1 to 12 of 342 entries