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Showing 1 to 12 of 203 entries
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The influence of pioglitazone on the plasma amino acid profile in patients with nonalcoholic steatohepatitis (NASH).

Hepatology international

Kakazu E, Kondo Y, Ninomiya M, Kimura O, Nagasaki F, Ueno Y, Shimosegawa T.
PMID: 26201790
Hepatol Int. 2013 Jun;7(2):577-85. doi: 10.1007/s12072-012-9395-y. Epub 2012 Aug 14.

BACKGROUND AND AIMS: The peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand, piglitazone, enhances the degradation of branched-chain amino acids (BCAAs) in adipose tissue. However, it remains unknown whether pioglitazone influences the plasma amino acids (AA) profile in patients with nonalcoholic steatohepatitis...

Murine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis.

ISRN hepatology

Ninomiya M, Kondo Y, Shimosegawa T.
PMID: 27335818
ISRN Hepatol. 2012 Dec 12;2013:237870. doi: 10.1155/2013/237870. eCollection 2013.

In 1980, Ludwig et al. first reported patients of steatohepatitis who lacked a history of excessive alcohol consumption but showed liver histology resembling alcoholic hepatitis and progression to cirrhosis of the liver accompanied by inflammation and fibrosis. The development...

Sensitivity of polymerase chain reaction to determine chlamydia trachomatis eradication rate with levofloxacin therapy in patients with chlamydial cervicitis.

Current therapeutic research, clinical and experimental

Mikamo H, Ninomiya M, Tamaya T.
PMID: 24944386
Curr Ther Res Clin Exp. 2003 Jun;64(6):375-7. doi: 10.1016/S0011-393X(03)00088-2.

BACKGROUND: For the treatment of chlamydial cervicitis, a 7- to 14-day regimen with appropriate antibacterial agents (eg, macrolides, tetracycline, fluoroquinolones) has been recommended. Many clinicians in Japan have determined the eradication rate of cervical Chlamydia trachomatis by polymerase chain...

LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds.

Cytotechnology

Specian AF, Serpeloni JM, Tuttis K, Ribeiro DL, Cilião HL, Varanda EA, Sannomiya M, Martinez-Lopez W, Vilegas W, Cólus IM.
PMID: 27344148
Cytotechnology. 2016 Dec;68(6):2729-2744. doi: 10.1007/s10616-016-9998-6. Epub 2016 Jun 25.

Brazilian flora biodiversity has been widely investigated to identify effective and safe phytotherapeutic compounds. Among the investigated plant species, the Byrsonima genus exhibits promising biological activities. This study aimed at evaluating the cytotoxicity of B. correifolia, B. verbascifolia, B....

Soft Matter-Regulated Active Nanovalves Locally Self-Assembled in Femtoliter Nanofluidic Channels.

Advanced materials (Deerfield Beach, Fla.)

Xu Y, Shinomiya M, Harada A.
PMID: 26786725
Adv Mater. 2016 Mar 16;28(11):2209-16. doi: 10.1002/adma.201505132. Epub 2016 Jan 20.

Well-tailored thermoresponsive polymer brushes locally self-assembled in tiny nanofluidic channels enable the active regulation of femtoliter-scale fluids. Such soft-matter-regulated active nanovalves within nanofluidic channels can be extended to build well-controlled functional nanofluidic systems, allowing complex fluidic processes to be...

Erratum to: Testosterone stimulates glucose uptake and GLUT4 translocation through LKB1/AMPK signaling in 3T3-L1 adipocytes.

Endocrine

Mitsuhashi K, Senmaru T, Fukuda T, Yamazaki M, Shinomiya K, Ueno M, Kinoshita S, Kitawaki J, Katsuyama M, Tsujikawa M, Obayashi H, Nakamura N, Fukui M.
PMID: 26820143
Endocrine. 2016 May;52(2):402-3. doi: 10.1007/s12020-016-0864-2.

No abstract available.

Type A aortic dissection with transient myocardial ischemia caused by intimal flap inverting into the left ventricle.

Journal of echocardiography

Ishige A, Tanaka H, Ueda T, Ninomiya M, Ohtsuka T.
PMID: 27277179
J Echocardiogr. 2011 Sep;9(3):112-4. doi: 10.1007/s12574-010-0075-4. Epub 2010 Dec 28.

A 41-year-old man with sudden onset of chest oppression and downslope ST depression was diagnosed as having type A aortic dissection with angina pectoris and aortic regurgitation. Intraoperative transesophageal echocardiogram (TEE) showed intimal flap inverting into the left ventricle...

Role of G1 phase in the UV-induced apoptosis of EL-4 mouse lymphoma cells.

Apoptosis : an international journal on programmed cell death

Takemura T, Shinomiya N, Rokutanda M.
PMID: 14634275
Apoptosis. 1999 Aug;4(4):245-53. doi: 10.1023/a:1009600809008.

Although UV is known to induce apoptotic cell death to various animal cells, relationship between cell cycle and UV-induced apoptosis is still unclear. In this study, we investigated the role of G1 phase in UV-induced apoptosis by using EL-4...

Long-term outcome of patients with rheumatoid arthritis treated by multiple arthroplasty.

Modern rheumatology

Shinomiya F, Mima N, Hamada Y, Fuzimura T, Matsumoto S, Okada M, Hamada D.
PMID: 17029072
Mod Rheumatol. 2005;15(4):241-8. doi: 10.1007/s10165-005-0403-0.

We conducted a study of 82 patients with rheumatoid arthritis (RA) who had undergone multiple arthroplasty and investigated their clinical findings and clinical courses. We reviewed the significance of multiple arthroplasty in the treatment of RA, its problems, and...

Compressive stenosis of the left hepatic vein as a pathogenesis of postresectional liver failure: a case report.

Journal of medical case reports

Ninomiya M, Ikeda T.
PMID: 20509899
J Med Case Rep. 2010 May 28;4:163. doi: 10.1186/1752-1947-4-163.

INTRODUCTION: Postresectional liver failure (PLF) is a devastating and fatal complication of major hepatic resection, and we do not have a full understanding of the pathogenic mechanisms involved. No reliable treatment other than liver transplantation currently exists for PLF.CASE...

Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-β-induced epithelial-mesenchymal transition in hepatocellular carcinoma.

Hepatology research : the official journal of the Japan Society of Hepatology

Kogure T, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Shimosegawa T.
PMID: 23789939
Hepatol Res. 2014 Aug;44(8):907-19. doi: 10.1111/hepr.12188. Epub 2013 Jul 21.

AIM: Epithelial-mesenchymal transition (EMT) is a crucial process during cancer invasion and metastasis, which is accompanied by the suppressed expression of E-cadherin initiated by stimuli such as transforming growth factor (TGF)-β. Recent studies have shown that the epigenetic regulation...

Indications of total ankle arthroplasty for rheumatoid arthritis: evaluation at 5 years or more after the operation.

Modern rheumatology

Shinomiya F, Okada M, Hamada Y, Fujimura T, Hamada D.
PMID: 24387175
Mod Rheumatol. 2003 Jun;13(2):153-9. doi: 10.3109/s10165-002-0215-4.

Abstract The postoperative results of total ankle arthroplasty (TAA) were surveyed, and the indications of TAA for rheumatoid arthritis (RA) were examined. We have performed TAA in properly selected patients with indication of ankle joint destruction due to RA....

Showing 1 to 12 of 203 entries