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Mono- and Bis-Alkylation of Glyoxal-Bridged Tetraazamacrocycles Using Mechanochemistry.

The Journal of organic chemistry

Abdulwahaab BH, Burke BP, Domarkas J, Silversides JD, Prior TJ, Archibald SJ.
PMID: 26670783
J Org Chem. 2016 Feb 05;81(3):890-8. doi: 10.1021/acs.joc.5b02464. Epub 2016 Jan 21.

Glyoxal-bridged bisaminal tetraazamacrocyclic derivatives of 1,4,7,10-tetraazacyclododecane (cyclen) and 1,4,8,11-tetraazacyclotetradecane (cyclam) can be N-functionalized to incorporate coordinating groups or for conjugation to biomolecules. Herein, we present an improved N-functionalization methodology using mechanochemistry which reduces reaction times in comparison with conventional...

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Abdulwahaab BH, Burke BP, Domarkas J, et al. Mono- and Bis-Alkylation of Glyoxal-Bridged Tetraazamacrocycles Using Mechanochemistry. J Org Chem. 2016;81(3):890-8doi: 10.1021/acs.joc.5b02464.
Abdulwahaab, B. H., Burke, B. P., Domarkas, J., Silversides, J. D., Prior, T. J., & Archibald, S. J. (2016). Mono- and Bis-Alkylation of Glyoxal-Bridged Tetraazamacrocycles Using Mechanochemistry. The Journal of organic chemistry, 81(3), 890-8. https://doi.org/10.1021/acs.joc.5b02464
Abdulwahaab, Bassim H, et al. "Mono- and Bis-Alkylation of Glyoxal-Bridged Tetraazamacrocycles Using Mechanochemistry." The Journal of organic chemistry vol. 81,3 (2016): 890-8. doi: https://doi.org/10.1021/acs.joc.5b02464
Abdulwahaab BH, Burke BP, Domarkas J, Silversides JD, Prior TJ, Archibald SJ. Mono- and Bis-Alkylation of Glyoxal-Bridged Tetraazamacrocycles Using Mechanochemistry. J Org Chem. 2016 Feb 05;81(3):890-8. doi: 10.1021/acs.joc.5b02464. Epub 2016 Jan 21. PMID: 26670783.
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High-Risk Cardiac Disease in Pregnancy: Part II.

Journal of the American College of Cardiology

Elkayam U, Goland S, Pieper PG, Silversides CK.
PMID: 27443948
J Am Coll Cardiol. 2016 Aug 02;68(5):502-516. doi: 10.1016/j.jacc.2016.05.050. Epub 2016 Jul 18.

Heart disease continues to be the leading cause of nonobstetric maternal morbidity and mortality. Early diagnosis and appropriate care can lead to prevention of complications and improvement of pregnancy outcome. This paper continues the review and provides recommendations for...

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Elkayam U, Goland S, Pieper PG, et al. High-Risk Cardiac Disease in Pregnancy: Part II. J Am Coll Cardiol. 2016;68(5):502-516doi: 10.1016/j.jacc.2016.05.050.
Elkayam, U., Goland, S., Pieper, P. G., & Silversides, C. K. (2016). High-Risk Cardiac Disease in Pregnancy: Part II. Journal of the American College of Cardiology, 68(5), 502-516. https://doi.org/10.1016/j.jacc.2016.05.050
Elkayam, Uri, et al. "High-Risk Cardiac Disease in Pregnancy: Part II." Journal of the American College of Cardiology vol. 68,5 (2016): 502-516. doi: https://doi.org/10.1016/j.jacc.2016.05.050
Elkayam U, Goland S, Pieper PG, Silversides CK. High-Risk Cardiac Disease in Pregnancy: Part II. J Am Coll Cardiol. 2016 Aug 02;68(5):502-516. doi: 10.1016/j.jacc.2016.05.050. Epub 2016 Jul 18. PMID: 27443948.
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Immunization of cattle against modified peptides of gonadotropin releasing hormone conjugated to carriers: Effectiveness of Freund's and alternative adjuvants.

Theriogenology

Goubau S, Silversides DW, Gonzalez A, Laarveld B, Mapletoft RJ, Murphy BD.
PMID: 16726703
Theriogenology. 1989 Oct;32(4):557-67. doi: 10.1016/0093-691x(89)90277-x.

Two gonadotropin-releasing hormone (GnRH) peptides with a cystein substitution of the first (C1-GnRH) or tenth (C10-GnRH) amino acid were conjugated to ovalbumin and equine serum albumin, respectively, via the sulfhydryl group of the introduced cysteine. Animals were immunized three...

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Goubau S, Silversides DW, Gonzalez A, et al. Immunization of cattle against modified peptides of gonadotropin releasing hormone conjugated to carriers: Effectiveness of Freund's and alternative adjuvants. Theriogenology. 1989;32(4):557-67doi: 10.1016/0093-691x(89)90277-x.
Goubau, S., Silversides, D. W., Gonzalez, A., Laarveld, B., Mapletoft, R. J., & Murphy, B. D. (1989). Immunization of cattle against modified peptides of gonadotropin releasing hormone conjugated to carriers: Effectiveness of Freund's and alternative adjuvants. Theriogenology, 32(4), 557-67. https://doi.org/10.1016/0093-691x(89)90277-x
Goubau, S, et al. "Immunization of cattle against modified peptides of gonadotropin releasing hormone conjugated to carriers: Effectiveness of Freund's and alternative adjuvants." Theriogenology vol. 32,4 (1989): 557-67. doi: https://doi.org/10.1016/0093-691x(89)90277-x
Goubau S, Silversides DW, Gonzalez A, Laarveld B, Mapletoft RJ, Murphy BD. Immunization of cattle against modified peptides of gonadotropin releasing hormone conjugated to carriers: Effectiveness of Freund's and alternative adjuvants. Theriogenology. 1989 Oct;32(4):557-67. doi: 10.1016/0093-691x(89)90277-x. PMID: 16726703.
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Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate.

Acta crystallographica. Section C, Crystal structure communications

McClain JM, Maples DL, Maples RD, Matz DL, Harris SM, Nelson AD, Silversides JD, Archibald SJ, Hubin TJ.
PMID: 17088625
Acta Crystallogr C. 2006 Nov;62:m553-5. doi: 10.1107/S0108270106040765. Epub 2006 Oct 31.

The title compound, [FeCl2(C12H26N4)]PF6, is the first mononuclear Fe3+ complex of an ethylene cross-bridged tetraaza-macrocycle to be structurally characterized. Comparison with the mononuclear Fe2+ complex of the same ligand shows that the smaller Fe3+ ion is more fully encapsulated...

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McClain JM, Maples DL, Maples RD, et al. Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate. Acta Crystallogr C. 2006;62:m553-5doi: 10.1107/S0108270106040765.
McClain, J. M., Maples, D. L., Maples, R. D., Matz, D. L., Harris, S. M., Nelson, A. D., Silversides, J. D., Archibald, S. J., & Hubin, T. J. (2006). Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate. Acta crystallographica. Section C, Crystal structure communications, 62m553-5. https://doi.org/10.1107/S0108270106040765
McClain, James M, et al. "Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate." Acta crystallographica. Section C, Crystal structure communications vol. 62 (2006): m553-5. doi: https://doi.org/10.1107/S0108270106040765
McClain JM, Maples DL, Maples RD, Matz DL, Harris SM, Nelson AD, Silversides JD, Archibald SJ, Hubin TJ. Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate. Acta Crystallogr C. 2006 Nov;62:m553-5. doi: 10.1107/S0108270106040765. Epub 2006 Oct 31. PMID: 17088625.
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Cardiac magnetic resonance imaging characteristics and pregnancy outcomes in women with Mustard palliation for complete transposition of the great arteries.

International journal of cardiology. Heart & vasculature

Jimenez Juan L, Valente AM, Silversides CK, Geva T, Colman JM, Roche SL, Siu SC, Wald RM.
PMID: 28616516
Int J Cardiol Heart Vasc. 2016 Feb 10;10:54-59. doi: 10.1016/j.ijcha.2016.01.001. eCollection 2016 Mar.

BACKGROUND: Women with transposition of the great arteries (TGA) following atrial redirection surgery are at risk of pregnancy-associated arrhythmia and heart failure. The cardiovascular magnetic resonance imaging (CMR) characteristics of these women and the relationship of CMR findings to...

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Jimenez Juan L, Valente AM, Silversides CK, et al. Cardiac magnetic resonance imaging characteristics and pregnancy outcomes in women with Mustard palliation for complete transposition of the great arteries. Int J Cardiol Heart Vasc. 2016;10:54-59doi: 10.1016/j.ijcha.2016.01.001.
Jimenez Juan, L., Valente, A. M., Silversides, C. K., Geva, T., Colman, J. M., Roche, S. L., Siu, S. C., & Wald, R. M. (2016). Cardiac magnetic resonance imaging characteristics and pregnancy outcomes in women with Mustard palliation for complete transposition of the great arteries. International journal of cardiology. Heart & vasculature, 1054-59. https://doi.org/10.1016/j.ijcha.2016.01.001
Jimenez Juan, Laura, et al. "Cardiac magnetic resonance imaging characteristics and pregnancy outcomes in women with Mustard palliation for complete transposition of the great arteries." International journal of cardiology. Heart & vasculature vol. 10 (2016): 54-59. doi: https://doi.org/10.1016/j.ijcha.2016.01.001
Jimenez Juan L, Valente AM, Silversides CK, Geva T, Colman JM, Roche SL, Siu SC, Wald RM. Cardiac magnetic resonance imaging characteristics and pregnancy outcomes in women with Mustard palliation for complete transposition of the great arteries. Int J Cardiol Heart Vasc. 2016 Feb 10;10:54-59. doi: 10.1016/j.ijcha.2016.01.001. eCollection 2016 Mar. PMID: 28616516; PMCID: PMC5441339.
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Tachycardia-induced cardiomyopathy in three consecutive pregnancies.

Obstetric medicine

Pfaller B, Wichert-Schmitt B, Spears D, D'Souza R, Silversides CK.
PMID: 34880944
Obstet Med. 2021 Dec;14(4):269-271. doi: 10.1177/1753495X20958853. Epub 2020 Oct 06.

Tachycardia-induced cardiomyopathy is rare during pregnancy and is reversible when the underlying arrhythmia is effectively treated. Management can be complex due to the risks of antiarrhythmic medications and cardiac interventions on the developing fetus. The care requires a well-coordinated...

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Pfaller B, Wichert-Schmitt B, Spears D, et al. Tachycardia-induced cardiomyopathy in three consecutive pregnancies. Obstet Med. 2020;14(4):269-271doi: 10.1177/1753495X20958853.
Pfaller, B., Wichert-Schmitt, B., Spears, D., D'Souza, R., & Silversides, C. K. (2021). Tachycardia-induced cardiomyopathy in three consecutive pregnancies. Obstetric medicine, 14(4), 269-271. https://doi.org/10.1177/1753495X20958853
Pfaller, Birgit, et al. "Tachycardia-induced cardiomyopathy in three consecutive pregnancies." Obstetric medicine vol. 14,4 (2021): 269-271. doi: https://doi.org/10.1177/1753495X20958853
Pfaller B, Wichert-Schmitt B, Spears D, D'Souza R, Silversides CK. Tachycardia-induced cardiomyopathy in three consecutive pregnancies. Obstet Med. 2021 Dec;14(4):269-271. doi: 10.1177/1753495X20958853. Epub 2020 Oct 06. PMID: 34880944; PMCID: PMC8646211.
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Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report.

BMJ open

Connolly B, Milton-Cole R, Adams C, Battle C, McPeake J, Quasim T, Silversides J, Slack A, Waldmann C, Wilson E, Meyer J.
PMID: 34607869
BMJ Open. 2021 Oct 04;11(10):e052214. doi: 10.1136/bmjopen-2021-052214.

OBJECTIVE: To comprehensively update and survey the current provision of recovery, rehabilitation and follow-up services for adult critical care patients across the UK.DESIGN: Cross-sectional, self-administered, predominantly closed-question, electronic, online survey.SETTING: Institutions providing adult critical care services identified from national...

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Connolly B, Milton-Cole R, Adams C, et al. Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report. BMJ Open. 2021;11(10):e052214doi: 10.1136/bmjopen-2021-052214.
Connolly, B., Milton-Cole, R., Adams, C., Battle, C., McPeake, J., Quasim, T., Silversides, J., Slack, A., Waldmann, C., Wilson, E., Meyer, J. (2021). Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report. BMJ open, 11(10), e052214. https://doi.org/10.1136/bmjopen-2021-052214
Connolly, Bronwen, et al. "Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report." BMJ open vol. 11,10 (2021): e052214. doi: https://doi.org/10.1136/bmjopen-2021-052214
Connolly B, Milton-Cole R, Adams C, Battle C, McPeake J, Quasim T, Silversides J, Slack A, Waldmann C, Wilson E, Meyer J. Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report. BMJ Open. 2021 Oct 04;11(10):e052214. doi: 10.1136/bmjopen-2021-052214. PMID: 34607869; PMCID: PMC8491421.
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Maternal and Fetal Hemodynamic Adaptations to Pregnancy and Clinical Outcomes in Maternal Cardiac Disease.

The Canadian journal of cardiology

Ducas R, Saini BS, Yamamura K, Bhagra C, Marini D, Silversides CK, Roche SL, Colman JM, Kingdom JC, Sermer M, Hanneman K, Seed M, Wald RM.
PMID: 34224828
Can J Cardiol. 2021 Dec;37(12):1942-1950. doi: 10.1016/j.cjca.2021.06.015. Epub 2021 Jul 02.

BACKGROUND: Although insufficient maternal cardiac output (CO) has been implicated in poor outcomes in mothers with heart disease (HD), maternal-fetal interactions remain incompletely understood. We sought to quantify maternal-fetal hemodynamics with the use of magnetic resonance imaging (MRI) and...

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Ducas R, Saini BS, Yamamura K, et al. Maternal and Fetal Hemodynamic Adaptations to Pregnancy and Clinical Outcomes in Maternal Cardiac Disease. Can J Cardiol. 2021;37(12):1942-1950doi: 10.1016/j.cjca.2021.06.015.
Ducas, R., Saini, B. S., Yamamura, K., Bhagra, C., Marini, D., Silversides, C. K., Roche, S. L., Colman, J. M., Kingdom, J. C., Sermer, M., Hanneman, K., Seed, M., & Wald, R. M. (2021). Maternal and Fetal Hemodynamic Adaptations to Pregnancy and Clinical Outcomes in Maternal Cardiac Disease. The Canadian journal of cardiology, 37(12), 1942-1950. https://doi.org/10.1016/j.cjca.2021.06.015
Ducas, Robin, et al. "Maternal and Fetal Hemodynamic Adaptations to Pregnancy and Clinical Outcomes in Maternal Cardiac Disease." The Canadian journal of cardiology vol. 37,12 (2021): 1942-1950. doi: https://doi.org/10.1016/j.cjca.2021.06.015
Ducas R, Saini BS, Yamamura K, Bhagra C, Marini D, Silversides CK, Roche SL, Colman JM, Kingdom JC, Sermer M, Hanneman K, Seed M, Wald RM. Maternal and Fetal Hemodynamic Adaptations to Pregnancy and Clinical Outcomes in Maternal Cardiac Disease. Can J Cardiol. 2021 Dec;37(12):1942-1950. doi: 10.1016/j.cjca.2021.06.015. Epub 2021 Jul 02. PMID: 34224828.
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Pregnancy in women with congenital heart disease.

Obstetric medicine

Hatton R, Silversides CK.
PMID: 27656256
Obstet Med. 2013 Dec;6(4):184-5. doi: 10.1177/1753495X13490150. Epub 2013 Dec 01.

No abstract available.

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Hatton R, Silversides CK. Pregnancy in women with congenital heart disease. Obstet Med. 2013;6(4):184-5doi: 10.1177/1753495X13490150.
Hatton, R., & Silversides, C. K. (2013). Pregnancy in women with congenital heart disease. Obstetric medicine, 6(4), 184-5. https://doi.org/10.1177/1753495X13490150
Hatton, Rachael, and Silversides, Candice K. "Pregnancy in women with congenital heart disease." Obstetric medicine vol. 6,4 (2013): 184-5. doi: https://doi.org/10.1177/1753495X13490150
Hatton R, Silversides CK. Pregnancy in women with congenital heart disease. Obstet Med. 2013 Dec;6(4):184-5. doi: 10.1177/1753495X13490150. Epub 2013 Dec 01. PMID: 27656256; PMCID: PMC5004324.
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Staphylococcal toxic shock syndrome: mechanisms and management.

Current infectious disease reports

Silversides JA, Lappin E, Ferguson AJ.
PMID: 21308522
Curr Infect Dis Rep. 2010 Sep;12(5):392-400. doi: 10.1007/s11908-010-0119-y.

Staphylococcal toxic shock syndrome is a rare complication of Staphylococcus aureus infection in which bacterial toxins act as superantigens, activating very large numbers of T cells and generating an overwhelming immune-mediated cytokine avalanche that manifests clinically as fever, rash,...

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Silversides JA, Lappin E, Ferguson AJ. Staphylococcal toxic shock syndrome: mechanisms and management. Curr Infect Dis Rep. 2010;12(5):392-400doi: 10.1007/s11908-010-0119-y.
Silversides, J. A., Lappin, E., & Ferguson, A. J. (2010). Staphylococcal toxic shock syndrome: mechanisms and management. Current infectious disease reports, 12(5), 392-400. https://doi.org/10.1007/s11908-010-0119-y
Silversides, Jonathan A, et al. "Staphylococcal toxic shock syndrome: mechanisms and management." Current infectious disease reports vol. 12,5 (2010): 392-400. doi: https://doi.org/10.1007/s11908-010-0119-y
Silversides JA, Lappin E, Ferguson AJ. Staphylococcal toxic shock syndrome: mechanisms and management. Curr Infect Dis Rep. 2010 Sep;12(5):392-400. doi: 10.1007/s11908-010-0119-y. PMID: 21308522.
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Evacuation peacetime.

Canadian hospital

SILVERSIDES FH.
PMID: 14778031
Can Hosp. 1950 Oct;27(10):35; passim.

No abstract available.

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SILVERSIDES FH. Evacuation peacetime. Can Hosp. 1950;27(10):35; passim
SILVERSIDES, F. H. (1950). Evacuation peacetime. Canadian hospital, 27(10), 35; passim.
SILVERSIDES, F H. "Evacuation peacetime." Canadian hospital vol. 27,10 (1950): 35; passim.
SILVERSIDES FH. Evacuation peacetime. Can Hosp. 1950 Oct;27(10):35; passim. PMID: 14778031.
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Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes.

Dalton transactions (Cambridge, England : 2003)

Silversides JD, Smith R, Archibald SJ.
PMID: 21455520
Dalton Trans. 2011 Jun 21;40(23):6289-97. doi: 10.1039/c0dt01395a. Epub 2011 Apr 01.

The synthesis of chelators that form high stability complexes with copper(II) isotopes and do not suffer from transchelation in vivo has been a goal for many chemists. Such chelators will facilitate the exploitation of the (64)Cu isotope (t(1/2) =...

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Silversides JD, Smith R, Archibald SJ. Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes. Dalton Trans. 2011;40(23):6289-97doi: 10.1039/c0dt01395a.
Silversides, J. D., Smith, R., & Archibald, S. J. (2011). Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes. Dalton transactions (Cambridge, England : 2003), 40(23), 6289-97. https://doi.org/10.1039/c0dt01395a
Silversides, Jon D, et al. "Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes." Dalton transactions (Cambridge, England : 2003) vol. 40,23 (2011): 6289-97. doi: https://doi.org/10.1039/c0dt01395a
Silversides JD, Smith R, Archibald SJ. Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes. Dalton Trans. 2011 Jun 21;40(23):6289-97. doi: 10.1039/c0dt01395a. Epub 2011 Apr 01. PMID: 21455520.
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Showing 1 to 12 of 49 entries