Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 31 entries
Sorted by: Best Match Show Resources per page
On the ozonolysis of unsaturated tosylhydrazones as a direct approach to diazocarbonyl compounds.

Organic & biomolecular chemistry

Fegheh-Hassanpour Y, Ebrahim F, Arif T, Sintim HO, Claridge TDW, Amin NT, Hodgson DM.
PMID: 29611856
Org Biomol Chem. 2018 Apr 25;16(16):2876-2884. doi: 10.1039/c8ob00435h.

The scope and limitations are described of reacting unsaturated tosylhydrazones with O3 followed by Et3N for the generation of 1,4- and 1,5-diazocarbonyl systems. Tosylhydrazones, from tosylhydrazide condensation with readily available δ- and ε-unsaturated α-ketoesters, led in the former case...

Cite
Fegheh-Hassanpour Y, Ebrahim F, Arif T, et al. On the ozonolysis of unsaturated tosylhydrazones as a direct approach to diazocarbonyl compounds. Org Biomol Chem. 2018;16(16):2876-2884doi: 10.1039/c8ob00435h.
Fegheh-Hassanpour, Y., Ebrahim, F., Arif, T., Sintim, H. O., Claridge, T. D. W., Amin, N. T., & Hodgson, D. M. (2018). On the ozonolysis of unsaturated tosylhydrazones as a direct approach to diazocarbonyl compounds. Organic & biomolecular chemistry, 16(16), 2876-2884. https://doi.org/10.1039/c8ob00435h
Fegheh-Hassanpour, Younes, et al. "On the ozonolysis of unsaturated tosylhydrazones as a direct approach to diazocarbonyl compounds." Organic & biomolecular chemistry vol. 16,16 (2018): 2876-2884. doi: https://doi.org/10.1039/c8ob00435h
Fegheh-Hassanpour Y, Ebrahim F, Arif T, Sintim HO, Claridge TDW, Amin NT, Hodgson DM. On the ozonolysis of unsaturated tosylhydrazones as a direct approach to diazocarbonyl compounds. Org Biomol Chem. 2018 Apr 25;16(16):2876-2884. doi: 10.1039/c8ob00435h. PMID: 29611856.
Copy Download .nbib Format: NLM
Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling.

Organic letters

Fegheh-Hassanpour Y, Arif T, Sintim HO, Al Mamari HH, Hodgson DM.
PMID: 30125117
Org Lett. 2018 Sep 07;20(17):5528. doi: 10.1021/acs.orglett.8b02330. Epub 2018 Aug 20.

No abstract available.

Cite
Fegheh-Hassanpour Y, Arif T, Sintim HO, et al. Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Org Lett. 2018;20(17):5528doi: 10.1021/acs.orglett.8b02330.
Fegheh-Hassanpour, Y., Arif, T., Sintim, H. O., Al Mamari, H. H., & Hodgson, D. M. (2018). Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Organic letters, 20(17), 5528. https://doi.org/10.1021/acs.orglett.8b02330
Fegheh-Hassanpour, Younes, et al. "Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling." Organic letters vol. 20,17 (2018): 5528. doi: https://doi.org/10.1021/acs.orglett.8b02330
Fegheh-Hassanpour Y, Arif T, Sintim HO, Al Mamari HH, Hodgson DM. Correction to Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Org Lett. 2018 Sep 07;20(17):5528. doi: 10.1021/acs.orglett.8b02330. Epub 2018 Aug 20. PMID: 30125117.
Copy Download .nbib Format: NLM
Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP.

Journal of oral microbiology

Onyedibe KI, Elmanfi S, Aryal UK, Könönen E, Gürsoy UK, Sintim HO.
PMID: 34992733
J Oral Microbiol. 2021 Dec 29;14(1):2003617. doi: 10.1080/20002297.2021.2003617. eCollection 2022.

BACKGROUND: Constant exposure of human gingival fibroblasts (HGFs) to oral pathogens trigger selective immune responses. Recently, the activation of immune response to cyclic dinucleotides (CDNs) via STING has come to the forefront. Reports show that other proteins outside the...

Cite
Onyedibe KI, Elmanfi S, Aryal UK, et al. Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP. J Oral Microbiol. 2021;14(1):2003617doi: 10.1080/20002297.2021.2003617.
Onyedibe, K. I., Elmanfi, S., Aryal, U. K., Könönen, E., Gürsoy, U. K., & Sintim, H. O. (2022). Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP. Journal of oral microbiology, 14(1), 2003617. https://doi.org/10.1080/20002297.2021.2003617
Onyedibe, Kenneth I, et al. "Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP." Journal of oral microbiology vol. 14,1 (2022): 2003617. doi: https://doi.org/10.1080/20002297.2021.2003617
Onyedibe KI, Elmanfi S, Aryal UK, Könönen E, Gürsoy UK, Sintim HO. Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP. J Oral Microbiol. 2021 Dec 29;14(1):2003617. doi: 10.1080/20002297.2021.2003617. eCollection 2022. PMID: 34992733; PMCID: PMC8725719.
Copy Download .nbib Format: NLM
Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics.

ACS applied polymer materials

Xu J, Xu J, Moon H, Sintim HO, Lee H.
PMID: 32490375
ACS Appl Polym Mater. 2020 Feb 14;2(2):528-536. doi: 10.1021/acsapm.9b00950. Epub 2020 Feb 05.

Here, we describe the design, synthesis, and evaluation of two kinds of multifunctional zwitterionic linear poly(carboxybetaine thiophene) (PCBTh) and porous poly(carboxybetaine thiophene-

Cite
Xu J, Xu J, Moon H, et al. Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics. ACS Appl Polym Mater. 2020;2(2):528-536doi: 10.1021/acsapm.9b00950.
Xu, J., Xu, J., Moon, H., Sintim, H. O., & Lee, H. (2020). Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics. ACS applied polymer materials, 2(2), 528-536. https://doi.org/10.1021/acsapm.9b00950
Xu, Jinjia, et al. "Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics." ACS applied polymer materials vol. 2,2 (2020): 528-536. doi: https://doi.org/10.1021/acsapm.9b00950
Xu J, Xu J, Moon H, Sintim HO, Lee H. Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics. ACS Appl Polym Mater. 2020 Feb 14;2(2):528-536. doi: 10.1021/acsapm.9b00950. Epub 2020 Feb 05. PMID: 32490375; PMCID: PMC7266170.
Copy Download .nbib Format: NLM
Inhibition of .

Chemical science

Zheng Y, Tsuji G, Opoku-Temeng C, Sintim HO.
PMID: 30034764
Chem Sci. 2016 Sep 01;7(9):6238-6244. doi: 10.1039/c6sc02103d. Epub 2016 Jun 16.

Various important cellular processes in bacteria are controlled by c-di-GMP, such as motility, biofilm formation and virulence factors production. C-di-GMP is synthesized from two molecules of GTP by diguanylate cyclases (DGCs) and its actions are terminated by EAL or...

Cite
Zheng Y, Tsuji G, Opoku-Temeng C, et al. Inhibition of . Chem Sci. 2016;7(9):6238-6244doi: 10.1039/c6sc02103d.
Zheng, Y., Tsuji, G., Opoku-Temeng, C., & Sintim, H. O. (2016). Inhibition of . Chemical science, 7(9), 6238-6244. https://doi.org/10.1039/c6sc02103d
Zheng, Yue, et al. "Inhibition of ." Chemical science vol. 7,9 (2016): 6238-6244. doi: https://doi.org/10.1039/c6sc02103d
Zheng Y, Tsuji G, Opoku-Temeng C, Sintim HO. Inhibition of . Chem Sci. 2016 Sep 01;7(9):6238-6244. doi: 10.1039/c6sc02103d. Epub 2016 Jun 16. PMID: 30034764; PMCID: PMC6024209.
Copy Download .nbib Format: NLM
Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling.

Organic letters

Fegheh-Hassanpour Y, Arif T, Sintim HO, Al Mamari HH, Hodgson DM.
PMID: 28631488
Org Lett. 2017 Jul 07;19(13):3540-3543. doi: 10.1021/acs.orglett.7b01513. Epub 2017 Jun 20.

An asymmetric synthesis of (-)-6,7-dideoxysqualestatin H5 is reported. Key features of the synthesis include the following: (1) highly diastereoselective n-alkylation of a tartrate acetonide enolate and subsequent oxidation-hydrolysis to provide an asymmetric entry to a β-hydroxy-α-ketoester motif; (2) facilitation...

Cite
Fegheh-Hassanpour Y, Arif T, Sintim HO, et al. Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Org Lett. 2017;19(13):3540-3543doi: 10.1021/acs.orglett.7b01513.
Fegheh-Hassanpour, Y., Arif, T., Sintim, H. O., Al Mamari, H. H., & Hodgson, D. M. (2017). Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Organic letters, 19(13), 3540-3543. https://doi.org/10.1021/acs.orglett.7b01513
Fegheh-Hassanpour, Younes, et al. "Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling." Organic letters vol. 19,13 (2017): 3540-3543. doi: https://doi.org/10.1021/acs.orglett.7b01513
Fegheh-Hassanpour Y, Arif T, Sintim HO, Al Mamari HH, Hodgson DM. Synthesis of (-)-6,7-Dideoxysqualestatin H5 by Carbonyl Ylide Cycloaddition-Rearrangement and Cross-electrophile Coupling. Org Lett. 2017 Jul 07;19(13):3540-3543. doi: 10.1021/acs.orglett.7b01513. Epub 2017 Jun 20. PMID: 28631488.
Copy Download .nbib Format: NLM
Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures.

ACS omega

Mikek CG, West SJ, Gwin JC, Dayal N, Sintim HO, Lewis EA.
PMID: 30320266
ACS Omega. 2018 Sep 30;3(9):11582-11591. doi: 10.1021/acsomega.8b01621. Epub 2018 Sep 21.

Diminazene, DMZ, (or berenil) has been reported as a tight binder of G-quadruplexes. G-Quadruplex structures are often located in the promotor regions of oncogenes and may play a regulatory role in gene expression based on the stability of the...

Cite
Mikek CG, West SJ, Gwin JC, et al. Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures. ACS Omega. 2018;3(9):11582-11591doi: 10.1021/acsomega.8b01621.
Mikek, C. G., West, S. J., Gwin, J. C., Dayal, N., Sintim, H. O., & Lewis, E. A. (2018). Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures. ACS omega, 3(9), 11582-11591. https://doi.org/10.1021/acsomega.8b01621
Mikek, Clinton G, et al. "Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures." ACS omega vol. 3,9 (2018): 11582-11591. doi: https://doi.org/10.1021/acsomega.8b01621
Mikek CG, West SJ, Gwin JC, Dayal N, Sintim HO, Lewis EA. Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures. ACS Omega. 2018 Sep 30;3(9):11582-11591. doi: 10.1021/acsomega.8b01621. Epub 2018 Sep 21. PMID: 30320266; PMCID: PMC6173502.
Copy Download .nbib Format: NLM
Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry.

Analytical chemistry

Das S, Powe AM, Baker GA, Valle B, El-Zahab B, Sintim HO, Lowry M, Fakayode SO, McCarroll ME, Patonay G, Li M, Strongin RM, Geng ML, Warner IM.
PMID: 22050042
Anal Chem. 2012 Jan 17;84(2):597-625. doi: 10.1021/ac202904n. Epub 2011 Dec 13.

No abstract available.

Cite
Das S, Powe AM, Baker GA, et al. Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry. Anal Chem. 2011;84(2):597-625doi: 10.1021/ac202904n.
Das, S., Powe, A. M., Baker, G. A., Valle, B., El-Zahab, B., Sintim, H. O., Lowry, M., Fakayode, S. O., McCarroll, M. E., Patonay, G., Li, M., Strongin, R. M., Geng, M. L., & Warner, I. M. (2012). Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry. Analytical chemistry, 84(2), 597-625. https://doi.org/10.1021/ac202904n
Das, Susmita, et al. "Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry." Analytical chemistry vol. 84,2 (2012): 597-625. doi: https://doi.org/10.1021/ac202904n
Das S, Powe AM, Baker GA, Valle B, El-Zahab B, Sintim HO, Lowry M, Fakayode SO, McCarroll ME, Patonay G, Li M, Strongin RM, Geng ML, Warner IM. Molecular fluorescence, phosphorescence, and chemiluminescence spectrometry. Anal Chem. 2012 Jan 17;84(2):597-625. doi: 10.1021/ac202904n. Epub 2011 Dec 13. PMID: 22050042.
Copy Download .nbib Format: NLM
Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers.

Scientific reports

Zhou J, Roembke BT, Paragi G, Laguerre A, Sintim HO, Fonseca Guerra C, Monchaud D.
PMID: 27667717
Sci Rep. 2016 Sep 26;6:33888. doi: 10.1038/srep33888.

A twice-as-smart ligand is a small molecule that experiences a structural switch upon interaction with its target (i.e., smart ligand) that concomitantly triggers its fluorescence (i.e., smart probe). Prototypes of twice-as-smart ligands were recently developed to track and label...

Cite
Zhou J, Roembke BT, Paragi G, et al. Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers. Sci Rep. 2016;6:33888doi: 10.1038/srep33888.
Zhou, J., Roembke, B. T., Paragi, G., Laguerre, A., Sintim, H. O., Fonseca Guerra, C., & Monchaud, D. (2016). Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers. Scientific reports, 633888. https://doi.org/10.1038/srep33888
Zhou, Jie, et al. "Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers." Scientific reports vol. 6 (2016): 33888. doi: https://doi.org/10.1038/srep33888
Zhou J, Roembke BT, Paragi G, Laguerre A, Sintim HO, Fonseca Guerra C, Monchaud D. Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers. Sci Rep. 2016 Sep 26;6:33888. doi: 10.1038/srep33888. PMID: 27667717; PMCID: PMC5036188.
Copy Download .nbib Format: NLM
Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria.

RSC medicinal chemistry

Naclerio GA, Abutaleb NS, Onyedibe KI, Seleem MN, Sintim HO.
PMID: 33479609
RSC Med Chem. 2019 Dec 16;11(1):102-110. doi: 10.1039/c9md00391f. eCollection 2020 Jan 01.

According to the Centers for Disease Control and Prevention (CDC), methicillin-resistant

Cite
Naclerio GA, Abutaleb NS, Onyedibe KI, et al. Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. RSC Med Chem. 2019;11(1):102-110doi: 10.1039/c9md00391f.
Naclerio, G. A., Abutaleb, N. S., Onyedibe, K. I., Seleem, M. N., & Sintim, H. O. (2020). Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. RSC medicinal chemistry, 11(1), 102-110. https://doi.org/10.1039/c9md00391f
Naclerio, George A, et al. "Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria." RSC medicinal chemistry vol. 11,1 (2020): 102-110. doi: https://doi.org/10.1039/c9md00391f
Naclerio GA, Abutaleb NS, Onyedibe KI, Seleem MN, Sintim HO. Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. RSC Med Chem. 2019 Dec 16;11(1):102-110. doi: 10.1039/c9md00391f. eCollection 2020 Jan 01. PMID: 33479609; PMCID: PMC7536820.
Copy Download .nbib Format: NLM
Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?.

Pathogens (Basel, Switzerland)

Elmanfi S, Yilmaz M, Ong WWS, Yeboah KS, Sintim HO, Gürsoy M, Könönen E, Gürsoy UK.
PMID: 34070809
Pathogens. 2021 May 30;10(6). doi: 10.3390/pathogens10060675.

Host cells can recognize cytosolic double-stranded DNAs and endogenous second messengers as cyclic dinucleotides-including c-di-GMP, c-di-AMP, and cGAMP-of invading microbes via the critical and essential innate immune signaling adaptor molecule known as STING. This recognition activates the innate immune...

Cite
Elmanfi S, Yilmaz M, Ong WWS, et al. Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?. Pathogens. 2021;10(6)doi: 10.3390/pathogens10060675.
Elmanfi, S., Yilmaz, M., Ong, W. W. S., Yeboah, K. S., Sintim, H. O., Gürsoy, M., Könönen, E., & Gürsoy, U. K. (2021). Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?. Pathogens (Basel, Switzerland), 10(6), . https://doi.org/10.3390/pathogens10060675
Elmanfi, Samira, et al. "Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?." Pathogens (Basel, Switzerland) vol. 10,6 (2021). doi: https://doi.org/10.3390/pathogens10060675
Elmanfi S, Yilmaz M, Ong WWS, Yeboah KS, Sintim HO, Gürsoy M, Könönen E, Gürsoy UK. Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?. Pathogens. 2021 May 30;10(6). doi: 10.3390/pathogens10060675. PMID: 34070809; PMCID: PMC8226932.
Copy Download .nbib Format: NLM
The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation.

Cell & bioscience

Ho ST, Jin R, Cheung DH, Huang JJ, Shaw PC.
PMID: 31210926
Cell Biosci. 2019 Jun 13;9:47. doi: 10.1186/s13578-019-0306-y. eCollection 2019.

BACKGROUND: Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in telomerase loading to telomeres. Nucleophosmin (NPM) can partially attenuate PinX1 inhibition of telomerase activity and NPM loading to hTERT requires...

Cite
Ho ST, Jin R, Cheung DH, et al. The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation. Cell Biosci. 2019;9:47doi: 10.1186/s13578-019-0306-y.
Ho, S. T., Jin, R., Cheung, D. H., Huang, J. J., & Shaw, P. C. (2019). The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation. Cell & bioscience, 947. https://doi.org/10.1186/s13578-019-0306-y
Ho, Sai-Tim, et al. "The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation." Cell & bioscience vol. 9 (2019): 47. doi: https://doi.org/10.1186/s13578-019-0306-y
Ho ST, Jin R, Cheung DH, Huang JJ, Shaw PC. The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation. Cell Biosci. 2019 Jun 13;9:47. doi: 10.1186/s13578-019-0306-y. eCollection 2019. PMID: 31210926; PMCID: PMC6567508.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 31 entries