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The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses.

International journal of epidemiology

Rasheed H, Zheng J, Rees J, Sanderson E, Thomas L, Richardson TG, Fang S, Bekkevold OJ, Stovner EB, Gabrielsen ME, Skogholt AH, Romundstad S, Brumpton B, Hallan S, Willer C, Burgess S, Hveem K, Davey Smith G, Gaunt TR, Åsvold BO.
PMID: 34151951
Int J Epidemiol. 2021 Nov 10;50(5):1569-1579. doi: 10.1093/ije/dyab014.

BACKGROUND: The causal nature of the observed associations between serum lipids and apolipoproteins and kidney function are unclear.METHODS: Using two-sample and multivariable Mendelian randomization (MR), we examined the causal effects of serum lipids and apolipoproteins on kidney function, indicated...

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Rasheed H, Zheng J, Rees J, et al. The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses. Int J Epidemiol. 2021;50(5):1569-1579doi: 10.1093/ije/dyab014.
Rasheed, H., Zheng, J., Rees, J., Sanderson, E., Thomas, L., Richardson, T. G., Fang, S., Bekkevold, O. J., Stovner, E. B., Gabrielsen, M. E., Skogholt, A. H., Romundstad, S., Brumpton, B., Hallan, S., Willer, C., Burgess, S., Hveem, K., Davey Smith, G., Gaunt, T. R., & Åsvold, B. O. (2021). The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses. International journal of epidemiology, 50(5), 1569-1579. https://doi.org/10.1093/ije/dyab014
Rasheed, Humaira, et al. "The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses." International journal of epidemiology vol. 50,5 (2021): 1569-1579. doi: https://doi.org/10.1093/ije/dyab014
Rasheed H, Zheng J, Rees J, Sanderson E, Thomas L, Richardson TG, Fang S, Bekkevold OJ, Stovner EB, Gabrielsen ME, Skogholt AH, Romundstad S, Brumpton B, Hallan S, Willer C, Burgess S, Hveem K, Davey Smith G, Gaunt TR, Åsvold BO. The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses. Int J Epidemiol. 2021 Nov 10;50(5):1569-1579. doi: 10.1093/ije/dyab014. PMID: 34151951; PMCID: PMC8580277.
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Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34822786
Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003.

No abstract available.

Cite
Boer CG, Hatzikotoulas K, Southam L, et al. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021;184(24):6003-6005doi: 10.1016/j.cell.2021.11.003.
Boer, C. G., Hatzikotoulas, K., Southam, L., Stefánsdóttir, L., Zhang, Y., Coutinho de Almeida, R., Wu, T. T., Zheng, J., Hartley, A., Teder-Laving, M., Skogholt, A. H., Terao, C., Zengini, E., Alexiadis, G., Barysenka, A., Bjornsdottir, G., Gabrielsen, M. E., Gilly, A., Ingvarsson, T., Johnsen, M. B., Jonsson, H., Kloppenburg, M., Luetge, A., Lund, S. H., Mägi, R., Mangino, M., Nelissen, R. R. G. H. H., Shivakumar, M., Steinberg, J., Takuwa, H., Thomas, L. F., Tuerlings, M., Babis, G. C., Yin Cheung, J. P., Kang, J. H., Kraft, P., Lietman, S. A., Samartzis, D., Slagboom, P. E., Stefansson, K., Thorsteinsdottir, U., Tobias, J. H., Uitterlinden, A. G., Winsvold, B., Zwart, J. A., Smith, G. D., Sham, P. C., Thorleifsson, G., Gaunt, T. R., Morris, A. P., Valdes, A. M., Tsezou, A., Cheah, K. S. E., Ikegawa, S., Hveem, K., Esko, T., Wilkinson, J. M., Meulenbelt, I., Michael Lee, M. T., van Meurs, J. B. J., Styrkársdóttir, U., & Zeggini, E. (2021). Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell, 184(24), 6003-6005. https://doi.org/10.1016/j.cell.2021.11.003
Boer, Cindy G, et al. "Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations." Cell vol. 184,24 (2021): 6003-6005. doi: https://doi.org/10.1016/j.cell.2021.11.003
Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003. PMID: 34822786.
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Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.

Frontiers in neurology

Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB.
PMID: 34975738
Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021.

No abstract available.

Cite
Winsvold BS, Kitsos I, Thomas LF, et al. Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Front Neurol. 2021;12:789093doi: 10.3389/fneur.2021.789093.
Winsvold, B. S., Kitsos, I., Thomas, L. F., Skogholt, A. H., Gabrielsen, M. E., Zwart, J. A., & Nilsen, K. B. (2021). Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Frontiers in neurology, 12789093. https://doi.org/10.3389/fneur.2021.789093
Winsvold, Bendik S, et al. "Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci." Frontiers in neurology vol. 12 (2021): 789093. doi: https://doi.org/10.3389/fneur.2021.789093
Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB. Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021. PMID: 34975738; PMCID: PMC8718917.
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

Cite
Eijsbouts C, Zheng T, Kennedy NA, et al. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021;53(11):1543-1552doi: 10.1038/s41588-021-00950-8.
Eijsbouts, C., Zheng, T., Kennedy, N. A., Bonfiglio, F., Anderson, C. A., Moutsianas, L., Holliday, J., Shi, J., Shringarpure, S., Voda, A. I., Farrugia, G., Franke, A., Hübenthal, M., Abecasis, G., Zawistowski, M., Skogholt, A. H., Ness-Jensen, E., Hveem, K., Esko, T., Teder-Laving, M., Zhernakova, A., Camilleri, M., Boeckxstaens, G., Whorwell, P. J., Spiller, R., McVean, G., D'Amato, M., Jostins, L., & Parkes, M. (2021). Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nature genetics, 53(11), 1543-1552. https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts, Chris, et al. "Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders." Nature genetics vol. 53,11 (2021): 1543-1552. doi: https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05. PMID: 34741163; PMCID: PMC8571093.
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

Cite
Eijsbouts C, Zheng T, Kennedy NA, et al. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021;53(11):1543-1552doi: 10.1038/s41588-021-00950-8.
Eijsbouts, C., Zheng, T., Kennedy, N. A., Bonfiglio, F., Anderson, C. A., Moutsianas, L., Holliday, J., Shi, J., Shringarpure, S., Voda, A. I., Farrugia, G., Franke, A., Hübenthal, M., Abecasis, G., Zawistowski, M., Skogholt, A. H., Ness-Jensen, E., Hveem, K., Esko, T., Teder-Laving, M., Zhernakova, A., Camilleri, M., Boeckxstaens, G., Whorwell, P. J., Spiller, R., McVean, G., D'Amato, M., Jostins, L., & Parkes, M. (2021). Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nature genetics, 53(11), 1543-1552. https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts, Chris, et al. "Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders." Nature genetics vol. 53,11 (2021): 1543-1552. doi: https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05. PMID: 34741163; PMCID: PMC8571093.
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Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Davey Smith G, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Lee MTM, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34450027
Cell. 2021 Sep 02;184(18):4784-4818.e17. doi: 10.1016/j.cell.2021.07.038. Epub 2021 Aug 26.

Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 osteoarthritis phenotypes, 52 of which have not been associated...

Cite
Boer CG, Hatzikotoulas K, Southam L, et al. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021;184(18):4784-4818.e17doi: 10.1016/j.cell.2021.07.038.
Boer, C. G., Hatzikotoulas, K., Southam, L., Stefánsdóttir, L., Zhang, Y., Coutinho de Almeida, R., Wu, T. T., Zheng, J., Hartley, A., Teder-Laving, M., Skogholt, A. H., Terao, C., Zengini, E., Alexiadis, G., Barysenka, A., Bjornsdottir, G., Gabrielsen, M. E., Gilly, A., Ingvarsson, T., Johnsen, M. B., Jonsson, H., Kloppenburg, M., Luetge, A., Lund, S. H., Mägi, R., Mangino, M., Nelissen, R. R. G. H. H., Shivakumar, M., Steinberg, J., Takuwa, H., Thomas, L. F., Tuerlings, M., Babis, G. C., Cheung, J. P. Y., Kang, J. H., Kraft, P., Lietman, S. A., Samartzis, D., Slagboom, P. E., Stefansson, K., Thorsteinsdottir, U., Tobias, J. H., Uitterlinden, A. G., Winsvold, B., Zwart, J. A., Davey Smith, G., Sham, P. C., Thorleifsson, G., Gaunt, T. R., Morris, A. P., Valdes, A. M., Tsezou, A., Cheah, K. S. E., Ikegawa, S., Hveem, K., Esko, T., Wilkinson, J. M., Meulenbelt, I., Lee, M. T. M., van Meurs, J. B. J., Styrkársdóttir, U., & Zeggini, E. (2021). Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell, 184(18), 4784-4818.e17. https://doi.org/10.1016/j.cell.2021.07.038
Boer, Cindy G, et al. "Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations." Cell vol. 184,18 (2021): 4784-4818.e17. doi: https://doi.org/10.1016/j.cell.2021.07.038
Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Davey Smith G, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Lee MTM, van Meurs JBJ, Styrkársdóttir U, Zeggini E. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021 Sep 02;184(18):4784-4818.e17. doi: 10.1016/j.cell.2021.07.038. Epub 2021 Aug 26. PMID: 34450027; PMCID: PMC8459317.
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Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34822786
Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003.

No abstract available.

Cite
Boer CG, Hatzikotoulas K, Southam L, et al. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021;184(24):6003-6005doi: 10.1016/j.cell.2021.11.003.
Boer, C. G., Hatzikotoulas, K., Southam, L., Stefánsdóttir, L., Zhang, Y., Coutinho de Almeida, R., Wu, T. T., Zheng, J., Hartley, A., Teder-Laving, M., Skogholt, A. H., Terao, C., Zengini, E., Alexiadis, G., Barysenka, A., Bjornsdottir, G., Gabrielsen, M. E., Gilly, A., Ingvarsson, T., Johnsen, M. B., Jonsson, H., Kloppenburg, M., Luetge, A., Lund, S. H., Mägi, R., Mangino, M., Nelissen, R. R. G. H. H., Shivakumar, M., Steinberg, J., Takuwa, H., Thomas, L. F., Tuerlings, M., Babis, G. C., Yin Cheung, J. P., Kang, J. H., Kraft, P., Lietman, S. A., Samartzis, D., Slagboom, P. E., Stefansson, K., Thorsteinsdottir, U., Tobias, J. H., Uitterlinden, A. G., Winsvold, B., Zwart, J. A., Smith, G. D., Sham, P. C., Thorleifsson, G., Gaunt, T. R., Morris, A. P., Valdes, A. M., Tsezou, A., Cheah, K. S. E., Ikegawa, S., Hveem, K., Esko, T., Wilkinson, J. M., Meulenbelt, I., Michael Lee, M. T., van Meurs, J. B. J., Styrkársdóttir, U., & Zeggini, E. (2021). Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell, 184(24), 6003-6005. https://doi.org/10.1016/j.cell.2021.11.003
Boer, Cindy G, et al. "Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations." Cell vol. 184,24 (2021): 6003-6005. doi: https://doi.org/10.1016/j.cell.2021.11.003
Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003. PMID: 34822786; PMCID: PMC8658458.
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Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer.

Nature communications

Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO.
PMID: 34916535
Nat Commun. 2021 Dec 16;12(1):7354. doi: 10.1038/s41467-021-27675-w.

No abstract available.

Cite
Zhou W, Brumpton B, Kabil O, et al. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2021;12(1):7354doi: 10.1038/s41467-021-27675-w.
Zhou, W., Brumpton, B., Kabil, O., Gudmundsson, J., Thorleifsson, G., Weinstock, J., Zawistowski, M., Nielsen, J. B., Chaker, L., Medici, M., Teumer, A., Naitza, S., Sanna, S., Schultheiss, U. T., Cappola, A., Karjalainen, J., Kurki, M., Oneka, M., Taylor, P., Fritsche, L. G., Graham, S. E., Wolford, B. N., Overton, W., Rasheed, H., Haug, E. B., Gabrielsen, M. E., Skogholt, A. H., Surakka, I., Davey Smith, G., Pandit, A., Roychowdhury, T., Hornsby, W. E., Jonasson, J. G., Senter, L., Liyanarachchi, S., Ringel, M. D., Xu, L., Kiemeney, L. A., He, H., Netea-Maier, R. T., Mayordomo, J. I., Plantinga, T. S., Hrafnkelsson, J., Hjartarson, H., Sturgis, E. M., Palotie, A., Daly, M., Citterio, C. E., Arvan, P., Brummett, C. M., Boehnke, M., de la Chapelle, A., Stefansson, K., Hveem, K., Willer, C. J., & Åsvold, B. O. (2021). Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nature communications, 12(1), 7354. https://doi.org/10.1038/s41467-021-27675-w
Zhou, Wei, et al. "Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer." Nature communications vol. 12,1 (2021): 7354. doi: https://doi.org/10.1038/s41467-021-27675-w
Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2021 Dec 16;12(1):7354. doi: 10.1038/s41467-021-27675-w. PMID: 34916535.
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Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.

Frontiers in neurology

Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB.
PMID: 34975738
Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021.

No abstract available.

Cite
Winsvold BS, Kitsos I, Thomas LF, et al. Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Front Neurol. 2021;12:789093doi: 10.3389/fneur.2021.789093.
Winsvold, B. S., Kitsos, I., Thomas, L. F., Skogholt, A. H., Gabrielsen, M. E., Zwart, J. A., & Nilsen, K. B. (2021). Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Frontiers in neurology, 12789093. https://doi.org/10.3389/fneur.2021.789093
Winsvold, Bendik S, et al. "Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci." Frontiers in neurology vol. 12 (2021): 789093. doi: https://doi.org/10.3389/fneur.2021.789093
Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB. Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci. Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021. PMID: 34975738; PMCID: PMC8718917.
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Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer.

Nature communications

Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO.
PMID: 34916535
Nat Commun. 2021 Dec 16;12(1):7354. doi: 10.1038/s41467-021-27675-w.

No abstract available.

Cite
Zhou W, Brumpton B, Kabil O, et al. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2021;12(1):7354doi: 10.1038/s41467-021-27675-w.
Zhou, W., Brumpton, B., Kabil, O., Gudmundsson, J., Thorleifsson, G., Weinstock, J., Zawistowski, M., Nielsen, J. B., Chaker, L., Medici, M., Teumer, A., Naitza, S., Sanna, S., Schultheiss, U. T., Cappola, A., Karjalainen, J., Kurki, M., Oneka, M., Taylor, P., Fritsche, L. G., Graham, S. E., Wolford, B. N., Overton, W., Rasheed, H., Haug, E. B., Gabrielsen, M. E., Skogholt, A. H., Surakka, I., Davey Smith, G., Pandit, A., Roychowdhury, T., Hornsby, W. E., Jonasson, J. G., Senter, L., Liyanarachchi, S., Ringel, M. D., Xu, L., Kiemeney, L. A., He, H., Netea-Maier, R. T., Mayordomo, J. I., Plantinga, T. S., Hrafnkelsson, J., Hjartarson, H., Sturgis, E. M., Palotie, A., Daly, M., Citterio, C. E., Arvan, P., Brummett, C. M., Boehnke, M., de la Chapelle, A., Stefansson, K., Hveem, K., Willer, C. J., & Åsvold, B. O. (2021). Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nature communications, 12(1), 7354. https://doi.org/10.1038/s41467-021-27675-w
Zhou, Wei, et al. "Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer." Nature communications vol. 12,1 (2021): 7354. doi: https://doi.org/10.1038/s41467-021-27675-w
Zhou W, Brumpton B, Kabil O, Gudmundsson J, Thorleifsson G, Weinstock J, Zawistowski M, Nielsen JB, Chaker L, Medici M, Teumer A, Naitza S, Sanna S, Schultheiss UT, Cappola A, Karjalainen J, Kurki M, Oneka M, Taylor P, Fritsche LG, Graham SE, Wolford BN, Overton W, Rasheed H, Haug EB, Gabrielsen ME, Skogholt AH, Surakka I, Davey Smith G, Pandit A, Roychowdhury T, Hornsby WE, Jonasson JG, Senter L, Liyanarachchi S, Ringel MD, Xu L, Kiemeney LA, He H, Netea-Maier RT, Mayordomo JI, Plantinga TS, Hrafnkelsson J, Hjartarson H, Sturgis EM, Palotie A, Daly M, Citterio CE, Arvan P, Brummett CM, Boehnke M, de la Chapelle A, Stefansson K, Hveem K, Willer CJ, Åsvold BO. Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer. Nat Commun. 2021 Dec 16;12(1):7354. doi: 10.1038/s41467-021-27675-w. PMID: 34916535; PMCID: PMC8677795.
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Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.

Nature genetics

Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A, Dobson R, Velayudhan L, Heilbron K, Auton A, Sealock JM, Davis LK, Pedersen NL, Reynolds CA, Karlsson IK, Magnusson S, Stefansson H, Thordardottir S, Jonsson PV, Snaedal J, Zettergren A, Skoog I, Kern S, Waern M, Zetterberg H, Blennow K, Stordal E, Hveem K, Zwart JA, Athanasiu L, Selnes P, Saltvedt I, Sando SB, Ulstein I, Djurovic S, Fladby T, Aarsland D, Selbæk G, Ripke S, Stefansson K, Andreassen OA, Posthuma D.
PMID: 34773122
Nat Genet. 2021 Dec;53(12):1722. doi: 10.1038/s41588-021-00977-x.

No abstract available.

Cite
Wightman DP, Jansen IE, Savage JE, et al. Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. Nat Genet. 2021;53(12):1722doi: 10.1038/s41588-021-00977-x.
Wightman, D. P., Jansen, I. E., Savage, J. E., Shadrin, A. A., Bahrami, S., Holland, D., Rongve, A., Børte, S., Winsvold, B. S., Drange, O. K., Martinsen, A. E., Skogholt, A. H., Willer, C., Bråthen, G., Bosnes, I., Nielsen, J. B., Fritsche, L. G., Thomas, L. F., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B., Meisingset, T. W., Zhou, W., Proitsi, P., Hodges, A., Dobson, R., Velayudhan, L., Heilbron, K., Auton, A., Sealock, J. M., Davis, L. K., Pedersen, N. L., Reynolds, C. A., Karlsson, I. K., Magnusson, S., Stefansson, H., Thordardottir, S., Jonsson, P. V., Snaedal, J., Zettergren, A., Skoog, I., Kern, S., Waern, M., Zetterberg, H., Blennow, K., Stordal, E., Hveem, K., Zwart, J. A., Athanasiu, L., Selnes, P., Saltvedt, I., Sando, S. B., Ulstein, I., Djurovic, S., Fladby, T., Aarsland, D., Selbæk, G., Ripke, S., Stefansson, K., Andreassen, O. A., & Posthuma, D. (2021). Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. Nature genetics, 53(12), 1722. https://doi.org/10.1038/s41588-021-00977-x
Wightman, Douglas P, et al. "Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease." Nature genetics vol. 53,12 (2021): 1722. doi: https://doi.org/10.1038/s41588-021-00977-x
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A, Dobson R, Velayudhan L, Heilbron K, Auton A, Sealock JM, Davis LK, Pedersen NL, Reynolds CA, Karlsson IK, Magnusson S, Stefansson H, Thordardottir S, Jonsson PV, Snaedal J, Zettergren A, Skoog I, Kern S, Waern M, Zetterberg H, Blennow K, Stordal E, Hveem K, Zwart JA, Athanasiu L, Selnes P, Saltvedt I, Sando SB, Ulstein I, Djurovic S, Fladby T, Aarsland D, Selbæk G, Ripke S, Stefansson K, Andreassen OA, Posthuma D. Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. Nat Genet. 2021 Dec;53(12):1722. doi: 10.1038/s41588-021-00977-x. PMID: 34773122.
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Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.

Gut

Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, Brunak S, Buch S, Clausnitzer H, Datz C, Degenhardt F, Doniec M, Erikstrup C, Esko T, Forster M, Frey N, Fritsche LG, Gabrielsen ME, Gräßle T, Gsur A, Gross J, Hampe J, Hendricks A, Hinz S, Hveem K, Jongen J, Junker R, Karlsen TH, Hemmrich-Stanisak G, Kruis W, Kupcinskas J, Laubert T, Rosenstiel PC, Röcken C, Laudes M, Leendertz FH, Lieb W, Limperger V, Margetis N, Mätz-Rensing K, Németh CG, Ness-Jensen E, Nowak-Göttl U, Pandit A, Pedersen OB, Peleikis HG, Peuker K, Rodriguez CL, Rühlemann MC, Schniewind B, Schulzky M, Skieceviciene J, Tepel J, Thomas L, Uellendahl-Werth F, Ullum H, Vogel I, Volzke H, von Fersen L, von Schönfels W, Vanderwerff B, Wilking J, Wittig M, Zeissig S, Zobel M, Zawistowski M, Vacic V, Sazonova O, Noblin ES, Farrugia G, Beyder A, Wedel T, Kahlke V, Schafmayer C, D'Amato M, Franke A.
PMID: 33888516
Gut. 2021 Apr 22; doi: 10.1136/gutjnl-2020-323868. Epub 2021 Apr 22.

OBJECTIVE: Haemorrhoidal disease (HEM) affects a large and silently suffering fraction of the population but its aetiology, including suspected genetic predisposition, is poorly understood. We report the first genome-wide association study (GWAS) meta-analysis to identify genetic risk factors for...

Cite
Zheng T, Ellinghaus D, Juzenas S, et al. Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease. Gut. 2021;doi: 10.1136/gutjnl-2020-323868.
Zheng, T., Ellinghaus, D., Juzenas, S., Cossais, F., Burmeister, G., Mayr, G., Jørgensen, I. F., Teder-Laving, M., Skogholt, A. H., Chen, S., Strege, P. R., Ito, G., Banasik, K., Becker, T., Bokelmann, F., Brunak, S., Buch, S., Clausnitzer, H., Datz, C., Degenhardt, F., Doniec, M., Erikstrup, C., Esko, T., Forster, M., Frey, N., Fritsche, L. G., Gabrielsen, M. E., Gräßle, T., Gsur, A., Gross, J., Hampe, J., Hendricks, A., Hinz, S., Hveem, K., Jongen, J., Junker, R., Karlsen, T. H., Hemmrich-Stanisak, G., Kruis, W., Kupcinskas, J., Laubert, T., Rosenstiel, P. C., Röcken, C., Laudes, M., Leendertz, F. H., Lieb, W., Limperger, V., Margetis, N., Mätz-Rensing, K., Németh, C. G., Ness-Jensen, E., Nowak-Göttl, U., Pandit, A., Pedersen, O. B., Peleikis, H. G., Peuker, K., Rodriguez, C. L., Rühlemann, M. C., Schniewind, B., Schulzky, M., Skieceviciene, J., Tepel, J., Thomas, L., Uellendahl-Werth, F., Ullum, H., Vogel, I., Volzke, H., von Fersen, L., von Schönfels, W., Vanderwerff, B., Wilking, J., Wittig, M., Zeissig, S., Zobel, M., Zawistowski, M., Vacic, V., Sazonova, O., Noblin, E. S., Farrugia, G., Beyder, A., Wedel, T., Kahlke, V., Schafmayer, C., D'Amato, M., & Franke, A. (2021). Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease. Gut, . https://doi.org/10.1136/gutjnl-2020-323868
Zheng, Tenghao, et al. "Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease." Gut vol. (2021). doi: https://doi.org/10.1136/gutjnl-2020-323868
Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, Brunak S, Buch S, Clausnitzer H, Datz C, Degenhardt F, Doniec M, Erikstrup C, Esko T, Forster M, Frey N, Fritsche LG, Gabrielsen ME, Gräßle T, Gsur A, Gross J, Hampe J, Hendricks A, Hinz S, Hveem K, Jongen J, Junker R, Karlsen TH, Hemmrich-Stanisak G, Kruis W, Kupcinskas J, Laubert T, Rosenstiel PC, Röcken C, Laudes M, Leendertz FH, Lieb W, Limperger V, Margetis N, Mätz-Rensing K, Németh CG, Ness-Jensen E, Nowak-Göttl U, Pandit A, Pedersen OB, Peleikis HG, Peuker K, Rodriguez CL, Rühlemann MC, Schniewind B, Schulzky M, Skieceviciene J, Tepel J, Thomas L, Uellendahl-Werth F, Ullum H, Vogel I, Volzke H, von Fersen L, von Schönfels W, Vanderwerff B, Wilking J, Wittig M, Zeissig S, Zobel M, Zawistowski M, Vacic V, Sazonova O, Noblin ES, Farrugia G, Beyder A, Wedel T, Kahlke V, Schafmayer C, D'Amato M, Franke A. Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease. Gut. 2021 Apr 22; doi: 10.1136/gutjnl-2020-323868. Epub 2021 Apr 22. PMID: 33888516; PMCID: PMC8292596.
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