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Showing 1 to 12 of 19 entries
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Association Between Antimicrobial Prophylaxis With Double-Dose Cefuroxime and Surgical Site Infections in Patients Weighing 80 kg or More.

JAMA network open

Sommerstein R, Atkinson A, Kuster SP, Vuichard-Gysin D, Harbarth S, Troillet N, Widmer AF.
PMID: 34910149
JAMA Netw Open. 2021 Dec 01;4(12):e2138926. doi: 10.1001/jamanetworkopen.2021.38926.

IMPORTANCE: Many guidelines recommend a weight-adopted dose increase of cefuroxime for surgical antimicrobial prophylaxis (SAP). However, the evidence that this approach is associated with lower rates of surgical site infection (SSI) is limited.OBJECTIVE: To assess whether double-dose cefuroxime SAP...

Evolution of COVID-19 mortality over time: results from the Swiss hospital surveillance system (CH-SUR).

Swiss medical weekly

Roelens M, Martin A, Friker B, Sousa FM, Thiabaud A, Vidondo B, Buchter V, Gardiol C, Vonlanthen J, Balmelli C, Battegay M, Berger C, Buettcher M, Cusini A, Flury D, Heininger U, Niederer-Loher A, Riedel T, Schreiber PW, Sommerstein R, Troillet N, Tschudin-Sutter S, Vetter P, Bernhard-Stirnemann S, Corti N, Gaudenz R, Marschall J, Nussbaumer-Ochsner Y, Senn L, Vuichard-Gysin D, Zimmermann P, Zucol F, Iten A, Keiser O.
PMID: 34843180
Swiss Med Wkly. 2021 Nov 24;151:w30105. doi: 10.4414/smw.2021.w30105. eCollection 2021 Nov 22.

BACKGROUND: When the periods of time during and after the first wave of the ongoing SARS-CoV-2/COVID-19 pandemic in Europe are compared, the associated COVID-19 mortality seems to have decreased substantially. Various factors could explain this trend, including changes in...

Guidelines to Reduce Hospitalization Rates for Patients Receiving Curative-Intent Radiation Therapy During the COVID-19 Pandemic: Report From a Multicenter New York Area Institution.

Advances in radiation oncology

Chen WC, Teckie S, Somerstein G, Adair N, Potters L.
PMID: 32395672
Adv Radiat Oncol. 2020 May 11;5(4):621-627. doi: 10.1016/j.adro.2020.04.021. eCollection 2020.

As the coronavirus disease 2019 pandemic spreads around the globe, access to radiation therapy remains critical for patients with cancer. The priority for all radiation oncology departments is to protect the staff and to maintain operations in providing access...

An automated retrospective VAE-surveillance tool for future quality improvement studies.

Scientific reports

Wolffers O, Faltys M, Thomann J, Jakob SM, Marschall J, Merz TM, Sommerstein R.
PMID: 34782637
Sci Rep. 2021 Nov 15;11(1):22264. doi: 10.1038/s41598-021-01402-3.

Ventilator-associated pneumonia (VAP) is a frequent complication of mechanical ventilation and is associated with substantial morbidity and mortality. Accurate diagnosis of VAP relies in part on subjective diagnostic criteria. Surveillance according to ventilator-associated event (VAE) criteria may allow quick...

The effect of the COVID-19 pandemic on the epidemiology of positive blood cultures in Swiss intensive care units: a nationwide surveillance study.

Critical care (London, England)

Damonti L, Kronenberg A, Marschall J, Jent P, Sommerstein R, De Kraker MEA, Harbarth S, Gasser M, Buetti N.
PMID: 34809698
Crit Care. 2021 Nov 22;25(1):403. doi: 10.1186/s13054-021-03814-z.

BACKGROUND: Evidence about the impact of the pandemic of COVID-19 on the incidence rates of blood cultures contaminations and bloodstream infections in intensive care units (ICUs) remains scant. The objective of this study was to investigate the nationwide epidemiology...

Hospital outcomes of community-acquired COVID-19 versus influenza: Insights from the Swiss hospital-based surveillance of influenza and COVID-19.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Fröhlich GM, De Kraker MEA, Abbas M, Keiser O, Thiabaud A, Roelens M, Cusini A, Flury D, Schreiber PW, Buettcher M, Corti N, Vuichard-Gysin D, Troillet N, Sauser J, Gaudenz R, Damonti L, Balmelli C, Iten A, Widmer A, Harbarth S, Sommerstein R.
PMID: 34991775
Euro Surveill. 2022 Jan;27(1). doi: 10.2807/1560-7917.ES.2022.27.1.2001848.

BackgroundSince the onset of the COVID-19 pandemic, the disease has frequently been compared with seasonal influenza, but this comparison is based on little empirical data.AimThis study compares in-hospital outcomes for patients with community-acquired COVID-19 and patients with community-acquired influenza...

Association Between Antimicrobial Prophylaxis With Double-Dose Cefuroxime and Surgical Site Infections in Patients Weighing 80 kg or More.

JAMA network open

Sommerstein R, Atkinson A, Kuster SP, Vuichard-Gysin D, Harbarth S, Troillet N, Widmer AF.
PMID: 34910149
JAMA Netw Open. 2021 Dec 01;4(12):e2138926. doi: 10.1001/jamanetworkopen.2021.38926.

IMPORTANCE: Many guidelines recommend a weight-adopted dose increase of cefuroxime for surgical antimicrobial prophylaxis (SAP). However, the evidence that this approach is associated with lower rates of surgical site infection (SSI) is limited.OBJECTIVE: To assess whether double-dose cefuroxime SAP...

Droplet precautions on-site (DroPS) during the influenza season 2018/2019: a possible alternative to single room isolation for respiratory viral infections.

Antimicrobial resistance and infection control

Birrer M, Perrig M, Hobi F, Gfeller C, Atkinson A, Egger M, Bartholdi C, Aujesky D, Marschall J, Sommerstein R.
PMID: 35000584
Antimicrob Resist Infect Control. 2022 Jan 09;11(1):2. doi: 10.1186/s13756-021-01038-y.

BACKGROUND: The guideline-driven and widely implemented single room isolation strategy for respiratory viral infections (RVI) such as influenza or respiratory syncytial virus (RSV) can lead to a shortage of available hospital beds. We discuss our experience with the introduction...

An automated retrospective VAE-surveillance tool for future quality improvement studies.

Scientific reports

Wolffers O, Faltys M, Thomann J, Jakob SM, Marschall J, Merz TM, Sommerstein R.
PMID: 34782637
Sci Rep. 2021 Nov 15;11(1):22264. doi: 10.1038/s41598-021-01402-3.

Ventilator-associated pneumonia (VAP) is a frequent complication of mechanical ventilation and is associated with substantial morbidity and mortality. Accurate diagnosis of VAP relies in part on subjective diagnostic criteria. Surveillance according to ventilator-associated event (VAE) criteria may allow quick...

Interferon-driven deletion of antiviral B cells at the onset of chronic infection.

Science immunology

Fallet B, Narr K, Ertuna YI, Remy M, Sommerstein R, Cornille K, Kreutzfeldt M, Page N, Zimmer G, Geier F, Straub T, Pircher H, Larimore K, Greenberg PD, Merkler D, Pinschewer DD.
PMID: 27872905
Sci Immunol. 2016 Oct 21;1(4). doi: 10.1126/sciimmunol.aah6817.

Inadequate antibody responses and perturbed B cell compartments represent hallmarks of persistent microbial infections, but the mechanisms whereby persisting pathogens suppress humoral immunity remain poorly defined. Using adoptive transfer experiments in the context of a chronic lymphocytic choriomeningitis virus...

Distribution of pathogens and antimicrobial resistance in bacteraemia according to hospitalization duration: a nationwide surveillance study in Switzerland.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Buetti N, Marschall J, Timsit JF, Atkinson A, Kronenberg A, Sommerstein R.
PMID: 33933567
Clin Microbiol Infect. 2021 Dec;27(12):1820-1825. doi: 10.1016/j.cmi.2021.04.025. Epub 2021 Apr 30.

OBJECTIVES: Changing microorganism distributions and decreasing antibiotic susceptibility with increasing length of hospital stay have been demonstrated for the colonization or infection of selected organ systems. We wanted to describe microorganism distribution or antibiotic resistance in bacteraemia according to...

Three-dimensional imager.

Applied optics

Caulfield HJ, Somerstein S.
PMID: 20168577
Appl Opt. 1977 Mar 01;16(3):774. doi: 10.1364/AO.16.000774.

A mode-locked laser, a rotating beam splitter, and a streak camera are the primary components of an imager with the ability to record three-dimensional images of remote (up to several kilometers) objects in real time in broad daylight. Immediate...

Showing 1 to 12 of 19 entries