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Showing 1 to 11 of 11 entries
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Solid-phase synthesis and structural characterization of highly substituted hydroxyproline-based 2,5-diketopiperazines.

The Journal of organic chemistry

Bianco A, Sonksen CP, Roepstorff P, Briand JP.
PMID: 10774043
J Org Chem. 2000 Apr 07;65(7):2179-87. doi: 10.1021/jo991818+.

Two general solid-phase methods for the synthesis of a new class of 2,5-diketopiperazines (DKPs) containing the trans-4-hydroxy-L-proline amino acid residue (Hyp) have been developed. An N-protected hydroxyproline methyl ester was linked through the hydroxyl function to the Ellman resin....

Vibratory Stimulation of Ejaculation Yields Increased Motile Spermatozoa, Compared with Electroejaculation, in Squirrel Monkeys (Saimiri boliviensis).

Contemporary topics in laboratory animal science

Yeoman RR, Ricker RB, Williams LE, Sonksen J, Abee CR.
PMID: 12456187
Contemp Top Lab Anim Sci. 1997 Jan;36(1):62-64.

Semen sample collection in squirrel monkeys has traditionally relied on electroejaculation (EE) via the rectum; how- ever, the yield is low when anesthesia is used. An alternative method has been advocated for men with spinal cord injury that relies...

A quantitative evaluation of the relative efficiency of gelatine and albumin in preventing insulin adsorption to glass.

Diabetologia

Sönksen PH, Ellis JP, Lowy C, Rutherford A, Nabarro JD.
PMID: 24173303
Diabetologia. 1966 Apr;1(3):208-10. doi: 10.1007/BF01257913.

Albumin has been found to be more effective than gelatine in preventing insulin loss from insulin containing solutions. It is probable that this has led to falsely elevated levels of insulin-like activity (ILA) reported with bio-assays. Preparations of crystalline...

Incidence of interruptive penicillin allergy alerts in patients with previously documented beta-lactam exposure: Potential for leveraging the electronic health record to identify erroneous allergies.

Infection control and hospital epidemiology

Van Groningen N, Duncan R, Cook-Wiens G, Kwong A, Sonesen M, Nuckols TK, Cassel SL, Pevnick JM.
PMID: 34387180
Infect Control Hosp Epidemiol. 2021 Aug 13;1-4. doi: 10.1017/ice.2021.329. Epub 2021 Aug 13.

BACKGROUND: Approximately 10% of patients report allergies to penicillin, yet >90% of these allergies are not clinically significant. Patients reporting penicillin allergies are often treated with second-line, non-β-lactam antibiotics that are typically broader spectrum and more toxic. Orders for...

The employment of diabetics.

British medical journal (Clinical research ed.)

Sönksen PH.
PMID: 6419879
Br Med J (Clin Res Ed). 1984 Jan 21;288(6412):239-40.
Free PMC Article

No abstract available.

Metal-organic framework nanoparticles for arsenic trioxide drug delivery.

Journal of materials chemistry. B

Ettlinger R, Sönksen M, Graf M, Moreno N, Denysenko D, Volkmer D, Kerl K, Bunzen H.
PMID: 32254655
J Mater Chem B. 2018 Oct 28;6(40):6481-6489. doi: 10.1039/c8tb01899e. Epub 2018 Sep 24.

Arsenic trioxide is a double-edged sword: On the one hand it is known as a poison, on the other hand it is used as an anticancer drug. Though effective in the treatment of leukaemia, arsenic trioxide has not been...

Growth hormone doping: a review.

Open access journal of sports medicine

Erotokritou-Mulligan I, Holt RI, Sönksen PH.
PMID: 24198576
Open Access J Sports Med. 2011 Jul 27;2:99-111. doi: 10.2147/OAJSM.S11626.

The use of growth hormone (GH) as a performance enhancing substance was first promoted in lay publications, long before scientists fully acknowledged its benefits. It is thought athletes currently use GH to enhance their athletic performance and to accelerate...

More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia.

Annals of translational medicine

Hellyer TP, McAuley DF, Walsh TS, Anderson N, Conway Morris A, Singh S, Dark P, Roy AI, Perkins GD, McMullan R, Emerson LM, Blackwood B, Wright SE, Kefala K, O'Kane CM, Baudouin SV, Paterson RL, Rostron AJ, Agus A, Bannard-Smith J, Robin NM, Welters ID, Bassford C, Yates B, Spencer C, Laha SK, Hulme J, Bonner S, Linnett V, Sonksen J, Van Den Broeck T, Boschman G, Keenan DWJ, Scott J, Allen AJ, Phair G, Parker J, Bowett SA, Simpson AJ.
PMID: 32794522
Ann Transl Med. 2020 Jul;8(13):840. doi: 10.21037/atm-20-3701.

No abstract available.

Current status and future prospects of nanomedicine for arsenic trioxide delivery to solid tumors.

Medicinal research reviews

Sönksen M, Kerl K, Bunzen H.
PMID: 34309879
Med Res Rev. 2022 Jan;42(1):374-398. doi: 10.1002/med.21844. Epub 2021 Jul 26.

Despite having a rich history as a poison, arsenic and its compounds have also gained a great reputation as promising anticancer drugs. As a pioneer, arsenic trioxide has been approved for the treatment of acute promyelocytic leukemia. Many in...

Why do endocrine profiles in elite athletes differ between sports?.

Clinical diabetes and endocrinology

Sönksen PH, Holt RIG, Böhning W, Guha N, Cowan DA, Bartlett C, Böhning D.
PMID: 29445518
Clin Diabetes Endocrinol. 2018 Feb 07;4:3. doi: 10.1186/s40842-017-0050-3. eCollection 2018.

BACKGROUND: Endocrine profiles have been measured on blood samples obtained immediately post-competition from 693 elite athletes from 15 Olympic Sports competing at National or International level; four were subsequently excluded leaving 689 for the current analysis.METHODS: Body composition was...

Erratum to: Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse.

BMC medical research methodology

Böhning D, Böhning W, Guha N, Cowan DA, Sönksen PH, Holt RI.
PMID: 27894262
BMC Med Res Methodol. 2016 Nov 28;16(1):164. doi: 10.1186/s12874-016-0262-8.

No abstract available.

Showing 1 to 11 of 11 entries