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Showing 1 to 12 of 160 entries
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Understanding the spectrum of haemophagocytic lymphohistiocytosis: update on diagnostic challenges and therapeutic options.

British journal of haematology

Brisse E, Matthys P, Wouters CH.
PMID: 27292929
Br J Haematol. 2016 Jul;174(2):175-87. doi: 10.1111/bjh.14144. Epub 2016 Jun 12.

The cytokine storm syndrome 'haemophagocytic lymphohistiocytosis' (HLH) is an under-recognized hyperinflammatory disorder, causing high morbidity and mortality risk in children and adults. It can be subdivided into a primary, genetic form and a secondary, acquired form that complicates diverse...

Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.

ACS medicinal chemistry letters

Koehler MF, Bergeron P, Choo EF, Lau K, Ndubaku C, Dudley D, Gibbons P, Sleebs BE, Rye CS, Nikolakopoulos G, Bui C, Kulasegaram S, Kersten WJ, Smith BJ, Czabotar PE, Colman PM, Huang DC, Baell JB, Watson KG, Hasvold L, Tao ZF, Wang L, Souers AJ, Elmore SW, Flygare JA, Fairbrother WJ, Lessene G.
PMID: 24944740
ACS Med Chem Lett. 2014 Mar 21;5(6):662-7. doi: 10.1021/ml500030p. eCollection 2014 Jun 12.

Because of the promise of BCL-2 antagonists in combating chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL), interest in additional selective antagonists of antiapoptotic proteins has grown. Beginning with a series of selective, potent BCL-XL antagonists containing an undesirable...

Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity.

Journal of medicinal chemistry

Bruncko M, Wang L, Sheppard GS, Phillips DC, Tahir SK, Xue J, Erickson S, Fidanze S, Fry E, Hasvold L, Jenkins GJ, Jin S, Judge RA, Kovar PJ, Madar D, Nimmer P, Park C, Petros AM, Rosenberg SH, Smith ML, Song X, Sun C, Tao ZF, Wang X, Xiao Y, Zhang H, Tse C, Leverson JD, Elmore SW, Souers AJ.
PMID: 25933255
J Med Chem. 2015 May 14;58(9):4089. doi: 10.1021/acs.jmedchem.5b00616. Epub 2015 May 01.

No abstract available.

A comparison of Stanford-Binet and Colored Raven Progressive Matrices IQs for children with low socioeconomic status.

Journal of consulting psychology

HIGGINS C, SIVERS CH.
PMID: 13611106
J Consult Psychol. 1958 Dec;22(6):465-8. doi: 10.1037/h0046808.

No abstract available.

The sequelae of a balloon cyst.

The Lahey Clinic bulletin

SOUDERS CR.
PMID: 18857142
Lahey Clin Bull. 1948 Apr;5(8):249-55.

No abstract available.

Letter to the editor.

Science (New York, N.Y.)

Somers RH.
PMID: 17837149
Science. 1967 May 05;156(3775):582. doi: 10.1126/science.156.3775.582.

No abstract available.

Effect of temperature on the radiation resistance of virulent Yersinia enterocolitica.

Meat science

Sommers CH, Niemira BA, Tunick M, Boyd G.
PMID: 22060857
Meat Sci. 2002 Jul;61(3):323-8. doi: 10.1016/s0309-1740(01)00200-5.

Yersinia enterocolitica, a food-borne pathogen, can be eliminated from meat using ionizing radiation. Commercial facilities may irradiate meat at refrigeration or frozen temperature, or packed in dry ice if the facility does not have refrigeration capabilities. The effect of...

Case of Congenital Absence of Continuity between the Large and Small Intestines.

British medical journal

Souter CH.
PMID: 20761798
Br Med J. 1904 Dec 03;2(2292):1512. doi: 10.1136/bmj.2.2292.1512.

No abstract available.

Evaluation of the clinical benefits of nanoparticle albumin-bound paclitaxel in women with metastatic breast cancer in British Columbia.

Current oncology (Toronto, Ont.)

Lohmann AE, Speers CH, Chia SK.
PMID: 23559872
Curr Oncol. 2013 Apr;20(2):97-103. doi: 10.3747/co.20.1256.

BACKGROUND: Altered formulations of taxanes may lack cross-resistance with standardly used solvent-based taxanes. The primary objective of the present study was to assess the clinical benefit of nanoparticle albumin-bound (nab)-paclitaxel in women with metastatic breast cancer previously treated with...

Outcomes of women with early-stage breast cancer receiving adjuvant trastuzumab.

Current oncology (Toronto, Ont.)

Seal MD, Speers CH, O'Reilly S, Gelmon KA, Ellard SL, Chia SK.
PMID: 22876145
Curr Oncol. 2012 Aug;19(4):197-201. doi: 10.3747/co.19.960.

INTRODUCTION: Large randomized trials assessing the benefit of adjuvant trastuzumab in early-stage breast cancer positive for the human epidermal growth factor receptor 2 (her2) have demonstrated a significant improvement in survival. The objective of the present study was to...

Atomic-hydrogen concentrations in solid D-T and T2.

Physical review. B, Condensed matter

Collins GW, Gaines JR, Maienschein JL, Mapoles ER, Souers PC.
PMID: 10001092
Phys Rev B Condens Matter. 1992 Jan 01;45(2):549-556. doi: 10.1103/physrevb.45.549.

No abstract available.

Temperature dependence of the magnetoresistance of sputtered Fe/Cr superlattices.

Physical review. B, Condensed matter

Bader SD, Brubaker ME, Conover M, Mattson JE, Qiu Z, Sowers CH.
PMID: 9998919
Phys Rev B Condens Matter. 1991 Nov 01;44(17):9378-9384. doi: 10.1103/physrevb.44.9378.

No abstract available.

Showing 1 to 12 of 160 entries