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Compact echelle spectrometer for occultation sounding of the Martian atmosphere: design and performance.

Applied optics

Korablev O, Montmessin F, Trokhimovsky A, Fedorova AA, Kiselev AV, Bertaux JL, Goultail JP, Belyaev DA, Stepanov AV, Titov AY, Kalinnikov YK.
PMID: 23400068
Appl Opt. 2013 Feb 10;52(5):1054-65. doi: 10.1364/AO.52.001054.

The echelle spectrometer TIMM-2 is the instrument developed for the unsuccessful Russian mission Phobos-Grunt. The instrument was dedicated to solar occultation studies of the Martian atmosphere by measuring the amount of methane, by sensitive measuring of other minor constituents,...

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Korablev O, Montmessin F, Trokhimovsky A, et al. Compact echelle spectrometer for occultation sounding of the Martian atmosphere: design and performance. Appl Opt. 2013;52(5):1054-65doi: 10.1364/AO.52.001054.
Korablev, O., Montmessin, F., Trokhimovsky, A., Fedorova, A. A., Kiselev, A. V., Bertaux, J. L., Goultail, J. P., Belyaev, D. A., Stepanov, A. V., Titov, A. Y., & Kalinnikov, Y. K. (2013). Compact echelle spectrometer for occultation sounding of the Martian atmosphere: design and performance. Applied optics, 52(5), 1054-65. https://doi.org/10.1364/AO.52.001054
Korablev, Oleg, et al. "Compact echelle spectrometer for occultation sounding of the Martian atmosphere: design and performance." Applied optics vol. 52,5 (2013): 1054-65. doi: https://doi.org/10.1364/AO.52.001054
Korablev O, Montmessin F, Trokhimovsky A, Fedorova AA, Kiselev AV, Bertaux JL, Goultail JP, Belyaev DA, Stepanov AV, Titov AY, Kalinnikov YK. Compact echelle spectrometer for occultation sounding of the Martian atmosphere: design and performance. Appl Opt. 2013 Feb 10;52(5):1054-65. doi: 10.1364/AO.52.001054. PMID: 23400068.
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The Role of Tumor-Derived Vesicles in the Regulation of Antitumor Immunity.

Acta naturae

Ukrainskaya VM, Rubtsov YP, Knorre VD, Maschan MA, Gabibov AG, Stepanov AV.
PMID: 31993233
Acta Naturae. 2019 Oct-Dec;11(4):33-41. doi: 10.32607/20758251-2019-11-4-33-41.

In this article, we present a comprehensive, updated, and elucidative review of the current knowledge on the function played by tumor-derived vesicles (TDVs) in the crosstalk between tumor and immune cells. Characterization of the structure, biogenesis, and the major...

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Ukrainskaya VM, Rubtsov YP, Knorre VD, et al. The Role of Tumor-Derived Vesicles in the Regulation of Antitumor Immunity. Acta Naturae. 2019;11(4):33-41doi: 10.32607/20758251-2019-11-4-33-41.
Ukrainskaya, V. M., Rubtsov, Y. P., Knorre, V. D., Maschan, M. A., Gabibov, A. G., & Stepanov, A. V. (2019). The Role of Tumor-Derived Vesicles in the Regulation of Antitumor Immunity. Acta naturae, 11(4), 33-41. https://doi.org/10.32607/20758251-2019-11-4-33-41
Ukrainskaya, V M, et al. "The Role of Tumor-Derived Vesicles in the Regulation of Antitumor Immunity." Acta naturae vol. 11,4 (2019): 33-41. doi: https://doi.org/10.32607/20758251-2019-11-4-33-41
Ukrainskaya VM, Rubtsov YP, Knorre VD, Maschan MA, Gabibov AG, Stepanov AV. The Role of Tumor-Derived Vesicles in the Regulation of Antitumor Immunity. Acta Naturae. 2019 Oct-Dec;11(4):33-41. doi: 10.32607/20758251-2019-11-4-33-41. PMID: 31993233; PMCID: PMC6977957.
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Soluble Cyanobacterial Carotenoprotein as a Robust Antioxidant Nanocarrier and Delivery Module.

Antioxidants (Basel, Switzerland)

Maksimov EG, Zamaraev AV, Parshina EY, Slonimskiy YB, Slastnikova TA, Abdrakhmanov AA, Babaev PA, Efimova SS, Ostroumova OS, Stepanov AV, Slutskaya EA, Ryabova AV, Friedrich T, Sluchanko NN.
PMID: 32942578
Antioxidants (Basel). 2020 Sep 15;9(9). doi: 10.3390/antiox9090869.

To counteract oxidative stress, antioxidants including carotenoids are highly promising, yet their exploitation is drastically limited by the poor bioavailability and fast photodestruction, whereas current delivery systems are far from being efficient. Here we demonstrate that the recently discovered...

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Maksimov EG, Zamaraev AV, Parshina EY, et al. Soluble Cyanobacterial Carotenoprotein as a Robust Antioxidant Nanocarrier and Delivery Module. Antioxidants (Basel). 2020;9(9)doi: 10.3390/antiox9090869.
Maksimov, E. G., Zamaraev, A. V., Parshina, E. Y., Slonimskiy, Y. B., Slastnikova, T. A., Abdrakhmanov, A. A., Babaev, P. A., Efimova, S. S., Ostroumova, O. S., Stepanov, A. V., Slutskaya, E. A., Ryabova, A. V., Friedrich, T., & Sluchanko, N. N. (2020). Soluble Cyanobacterial Carotenoprotein as a Robust Antioxidant Nanocarrier and Delivery Module. Antioxidants (Basel, Switzerland), 9(9), . https://doi.org/10.3390/antiox9090869
Maksimov, Eugene G, et al. "Soluble Cyanobacterial Carotenoprotein as a Robust Antioxidant Nanocarrier and Delivery Module." Antioxidants (Basel, Switzerland) vol. 9,9 (2020). doi: https://doi.org/10.3390/antiox9090869
Maksimov EG, Zamaraev AV, Parshina EY, Slonimskiy YB, Slastnikova TA, Abdrakhmanov AA, Babaev PA, Efimova SS, Ostroumova OS, Stepanov AV, Slutskaya EA, Ryabova AV, Friedrich T, Sluchanko NN. Soluble Cyanobacterial Carotenoprotein as a Robust Antioxidant Nanocarrier and Delivery Module. Antioxidants (Basel). 2020 Sep 15;9(9). doi: 10.3390/antiox9090869. PMID: 32942578; PMCID: PMC7555398.
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Death Receptors: New Opportunities in Cancer Therapy.

Acta naturae

Ukrainskaya VM, Stepanov AV, Glagoleva IS, Knorre VD, Belogurov AAJ, Gabibov AG.
PMID: 29104776
Acta Naturae. 2017 Jul-Sep;9(3):55-63.

This article offers a detailed review of the current approaches to anticancer therapy that target the death receptors of malignant cells. Here, we provide a comprehensive overview of the structure and function of death receptors and their ligands, describe...

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Ukrainskaya VM, Stepanov AV, Glagoleva IS, et al. Death Receptors: New Opportunities in Cancer Therapy. Acta Naturae. 2017;9(3):55-63
Ukrainskaya, V. M., Stepanov, A. V., Glagoleva, I. S., Knorre, V. D., Belogurov, A. A. J., & Gabibov, A. G. (2017). Death Receptors: New Opportunities in Cancer Therapy. Acta naturae, 9(3), 55-63.
Ukrainskaya, V M, et al. "Death Receptors: New Opportunities in Cancer Therapy." Acta naturae vol. 9,3 (2017): 55-63.
Ukrainskaya VM, Stepanov AV, Glagoleva IS, Knorre VD, Belogurov AAJ, Gabibov AG. Death Receptors: New Opportunities in Cancer Therapy. Acta Naturae. 2017 Jul-Sep;9(3):55-63. PMID: 29104776; PMCID: PMC5662274.
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Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers.

Proceedings of the National Academy of Sciences of the United States of America

Mokrushina YA, Golovin AV, Smirnov IV, Chatziefthimiou SD, Stepanova AV, Bobik TV, Zalevsky AO, Zlobin AS, Konovalov KA, Terekhov SS, Stepanov AV, Pipiya SO, Shamborant OG, Round E, Belogurov AA, Bourenkov G, Makarov AA, Wilmanns M, Xie J, Blackburn GM, Gabibov AG, Lerner RA.
PMID: 32859757
Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22841-22848. doi: 10.1073/pnas.2010317117. Epub 2020 Aug 28.

Quantum mechanics/molecular mechanics (QM/MM) maturation of an immunoglobulin (Ig) powered by supercomputation delivers novel functionality to this catalytic template and facilitates artificial evolution of biocatalysts. We here employ density functional theory-based (DFT-b) tight binding and funnel metadynamics to advance...

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Mokrushina YA, Golovin AV, Smirnov IV, et al. Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc Natl Acad Sci U S A. 2020;117(37):22841-22848doi: 10.1073/pnas.2010317117.
Mokrushina, Y. A., Golovin, A. V., Smirnov, I. V., Chatziefthimiou, S. D., Stepanova, A. V., Bobik, T. V., Zalevsky, A. O., Zlobin, A. S., Konovalov, K. A., Terekhov, S. S., Stepanov, A. V., Pipiya, S. O., Shamborant, O. G., Round, E., Belogurov, A. A., Bourenkov, G., Makarov, A. A., Wilmanns, M., Xie, J., Blackburn, G. M., Gabibov, A. G., & Lerner, R. A. (2020). Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proceedings of the National Academy of Sciences of the United States of America, 117(37), 22841-22848. https://doi.org/10.1073/pnas.2010317117
Mokrushina, Yuliana A, et al. "Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers." Proceedings of the National Academy of Sciences of the United States of America vol. 117,37 (2020): 22841-22848. doi: https://doi.org/10.1073/pnas.2010317117
Mokrushina YA, Golovin AV, Smirnov IV, Chatziefthimiou SD, Stepanova AV, Bobik TV, Zalevsky AO, Zlobin AS, Konovalov KA, Terekhov SS, Stepanov AV, Pipiya SO, Shamborant OG, Round E, Belogurov AA, Bourenkov G, Makarov AA, Wilmanns M, Xie J, Blackburn GM, Gabibov AG, Lerner RA. Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22841-22848. doi: 10.1073/pnas.2010317117. Epub 2020 Aug 28. PMID: 32859757; PMCID: PMC7502716.
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The study of operation modes of the self-magnetically insulated ion diode.

The Review of scientific instruments

Stepanov AV, Shamanin VI, Remnev GE.
PMID: 30927810
Rev Sci Instrum. 2019 Mar;90(3):033302. doi: 10.1063/1.5092127.

The operation modes of a self-magnetically insulated ion diode were studied. The plasma formation at the anode surface was found to be accompanied by an electron leakage current due to the bipolar high voltage pulse. The emitting anode surface...

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Stepanov AV, Shamanin VI, Remnev GE. The study of operation modes of the self-magnetically insulated ion diode. Rev Sci Instrum. 2019;90(3):033302doi: 10.1063/1.5092127.
Stepanov, A. V., Shamanin, V. I., & Remnev, G. E. (2019). The study of operation modes of the self-magnetically insulated ion diode. The Review of scientific instruments, 90(3), 033302. https://doi.org/10.1063/1.5092127
Stepanov, A V, et al. "The study of operation modes of the self-magnetically insulated ion diode." The Review of scientific instruments vol. 90,3 (2019): 033302. doi: https://doi.org/10.1063/1.5092127
Stepanov AV, Shamanin VI, Remnev GE. The study of operation modes of the self-magnetically insulated ion diode. Rev Sci Instrum. 2019 Mar;90(3):033302. doi: 10.1063/1.5092127. PMID: 30927810.
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Infrared Spectrometer for ExoMars: A Mast-Mounted Instrument for the Rover.

Astrobiology

Korablev OI, Dobrolensky Y, Evdokimova N, Fedorova AA, Kuzmin RO, Mantsevich SN, Cloutis EA, Carter J, Poulet F, Flahaut J, Griffiths A, Gunn M, Schmitz N, Martín-Torres J, Zorzano MP, Rodionov DS, Vago JL, Stepanov AV, Titov AY, Vyazovetsky NA, Trokhimovskiy AY, Sapgir AG, Kalinnikov YK, Ivanov YS, Shapkin AA, Ivanov AY.
PMID: 28731817
Astrobiology. 2017 Jun/Jul;17(6):542-564. doi: 10.1089/ast.2016.1543.

ISEM (Infrared Spectrometer for ExoMars) is a pencil-beam infrared spectrometer that will measure reflected solar radiation in the near infrared range for context assessment of the surface mineralogy in the vicinity of the ExoMars rover. The instrument will be...

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Korablev OI, Dobrolensky Y, Evdokimova N, et al. Infrared Spectrometer for ExoMars: A Mast-Mounted Instrument for the Rover. Astrobiology. 2017;17(6):542-564doi: 10.1089/ast.2016.1543.
Korablev, O. I., Dobrolensky, Y., Evdokimova, N., Fedorova, A. A., Kuzmin, R. O., Mantsevich, S. N., Cloutis, E. A., Carter, J., Poulet, F., Flahaut, J., Griffiths, A., Gunn, M., Schmitz, N., Martín-Torres, J., Zorzano, M. P., Rodionov, D. S., Vago, J. L., Stepanov, A. V., Titov, A. Y., Vyazovetsky, N. A., Trokhimovskiy, A. Y., Sapgir, A. G., Kalinnikov, Y. K., Ivanov, Y. S., Shapkin, A. A., & Ivanov, A. Y. (2017). Infrared Spectrometer for ExoMars: A Mast-Mounted Instrument for the Rover. Astrobiology, 17(6), 542-564. https://doi.org/10.1089/ast.2016.1543
Korablev, Oleg I, et al. "Infrared Spectrometer for ExoMars: A Mast-Mounted Instrument for the Rover." Astrobiology vol. 17,6 (2017): 542-564. doi: https://doi.org/10.1089/ast.2016.1543
Korablev OI, Dobrolensky Y, Evdokimova N, Fedorova AA, Kuzmin RO, Mantsevich SN, Cloutis EA, Carter J, Poulet F, Flahaut J, Griffiths A, Gunn M, Schmitz N, Martín-Torres J, Zorzano MP, Rodionov DS, Vago JL, Stepanov AV, Titov AY, Vyazovetsky NA, Trokhimovskiy AY, Sapgir AG, Kalinnikov YK, Ivanov YS, Shapkin AA, Ivanov AY. Infrared Spectrometer for ExoMars: A Mast-Mounted Instrument for the Rover. Astrobiology. 2017 Jun/Jul;17(6):542-564. doi: 10.1089/ast.2016.1543. PMID: 28731817.
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Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting.

Acta naturae

Stepanov AV, Belogurov AA, Kothapalli P, Shamborant OG, Knorre VD, Telegin GB, Ovsepyan AA, Ponomarenko NA, Deyev SM, Kaveri SV, Gabibov AG.
PMID: 26085947
Acta Naturae. 2015 Apr-Jun;7(2):74-9.

B cells play a crucial role in the development and pathogenesis of systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce antibodies, but also secrete pro-inflammatory cytokines and present specific autoantigens to T cells. The treatment of...

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Stepanov AV, Belogurov AA, Kothapalli P, et al. Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting. Acta Naturae. 2015;7(2):74-9
Stepanov, A. V., Belogurov, A. A., Kothapalli, P., Shamborant, O. G., Knorre, V. D., Telegin, G. B., Ovsepyan, A. A., Ponomarenko, N. A., Deyev, S. M., Kaveri, S. V., & Gabibov, A. G. (2015). Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting. Acta naturae, 7(2), 74-9.
Stepanov, A V, et al. "Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting." Acta naturae vol. 7,2 (2015): 74-9.
Stepanov AV, Belogurov AA, Kothapalli P, Shamborant OG, Knorre VD, Telegin GB, Ovsepyan AA, Ponomarenko NA, Deyev SM, Kaveri SV, Gabibov AG. Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting. Acta Naturae. 2015 Apr-Jun;7(2):74-9. PMID: 26085947; PMCID: PMC4463415.
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Molecular Approaches to Safe and Controlled Engineered T-cell Therapy.

Acta naturae

Kalinin RS, Petukhov AV, Knorre VD, Maschan MA, Stepanov AV, Gabibov AG.
PMID: 30116611
Acta Naturae. 2018 Apr-Jun;10(2):16-23.

Chimeric antigen receptor-modified T-cell therapy (CAR-T therapy) is one of the fastest developing areas of immuno-oncology. Over the past decade, it has revolutionized the cell therapy modality and expedited its pace of development, from optimization of the structure of...

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Kalinin RS, Petukhov AV, Knorre VD, et al. Molecular Approaches to Safe and Controlled Engineered T-cell Therapy. Acta Naturae. 2018;10(2):16-23
Kalinin, R. S., Petukhov, A. V., Knorre, V. D., Maschan, M. A., Stepanov, A. V., & Gabibov, A. G. (2018). Molecular Approaches to Safe and Controlled Engineered T-cell Therapy. Acta naturae, 10(2), 16-23.
Kalinin, R S, et al. "Molecular Approaches to Safe and Controlled Engineered T-cell Therapy." Acta naturae vol. 10,2 (2018): 16-23.
Kalinin RS, Petukhov AV, Knorre VD, Maschan MA, Stepanov AV, Gabibov AG. Molecular Approaches to Safe and Controlled Engineered T-cell Therapy. Acta Naturae. 2018 Apr-Jun;10(2):16-23. PMID: 30116611; PMCID: PMC6087824.
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Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy.

Acta naturae

Volkov DV, Tetz GV, Rubtsov YP, Stepanov AV, Gabibov AG.
PMID: 34707894
Acta Naturae. 2021 Jul-Sep;13(3):15-23. doi: 10.32607/actanaturae.11503.

Antitumor therapy, including adoptive immunotherapy, inevitably faces powerful counteraction from advanced cancer. If hematological malignancies are currently amenable to therapy with CAR-T lymphocytes (T-cells modified by the chimeric antigen receptor), solid tumors, unfortunately, show a significantly higher degree of...

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Volkov DV, Tetz GV, Rubtsov YP, et al. Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy. Acta Naturae. 2021;13(3):15-23doi: 10.32607/actanaturae.11503.
Volkov, D. V., Tetz, G. V., Rubtsov, Y. P., Stepanov, A. V., & Gabibov, A. G. (2021). Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy. Acta naturae, 13(3), 15-23. https://doi.org/10.32607/actanaturae.11503
Volkov, D V, et al. "Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy." Acta naturae vol. 13,3 (2021): 15-23. doi: https://doi.org/10.32607/actanaturae.11503
Volkov DV, Tetz GV, Rubtsov YP, Stepanov AV, Gabibov AG. Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy. Acta Naturae. 2021 Jul-Sep;13(3):15-23. doi: 10.32607/actanaturae.11503. PMID: 34707894; PMCID: PMC8526190.
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Antioxidant Activity of Styrylpyrones from Inonotus rheades (Agaricomycetes) Mycelium under Oxidative Stress in Thellungiella salsuginea Cell Suspension Culture.

International journal of medicinal mushrooms

Gornostai TG, Stepanov AV, Olennikov DN, Borovskii GG.
PMID: 34936307
Int J Med Mushrooms. 2021;23(11):37-44. doi: 10.1615/IntJMedMushrooms.2021040459.

This study examined effects of the styrylpyrone fraction from mycelium of hymenochaetoid species, Inonotus rheades (Agaricomycetes), on reactive oxygen species inhibition in Thellungiella salsuginea cell culture under oxidative stress. We identified antioxidant effects of styrylpyrones from I. rheades mycelium...

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Gornostai TG, Stepanov AV, Olennikov DN, et al. Antioxidant Activity of Styrylpyrones from Inonotus rheades (Agaricomycetes) Mycelium under Oxidative Stress in Thellungiella salsuginea Cell Suspension Culture. Int J Med Mushrooms. 2021;23(11):37-44doi: 10.1615/IntJMedMushrooms.2021040459.
Gornostai, T. G., Stepanov, A. V., Olennikov, D. N., & Borovskii, G. G. (2021). Antioxidant Activity of Styrylpyrones from Inonotus rheades (Agaricomycetes) Mycelium under Oxidative Stress in Thellungiella salsuginea Cell Suspension Culture. International journal of medicinal mushrooms, 23(11), 37-44. https://doi.org/10.1615/IntJMedMushrooms.2021040459
Gornostai, Tat'yana G, et al. "Antioxidant Activity of Styrylpyrones from Inonotus rheades (Agaricomycetes) Mycelium under Oxidative Stress in Thellungiella salsuginea Cell Suspension Culture." International journal of medicinal mushrooms vol. 23,11 (2021): 37-44. doi: https://doi.org/10.1615/IntJMedMushrooms.2021040459
Gornostai TG, Stepanov AV, Olennikov DN, Borovskii GG. Antioxidant Activity of Styrylpyrones from Inonotus rheades (Agaricomycetes) Mycelium under Oxidative Stress in Thellungiella salsuginea Cell Suspension Culture. Int J Med Mushrooms. 2021;23(11):37-44. doi: 10.1615/IntJMedMushrooms.2021040459. PMID: 34936307.
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Engineered Removal of PD-1 From the Surface of CD19 CAR-T Cells Results in Increased Activation and Diminished Survival.

Frontiers in molecular biosciences

Kalinin RS, Ukrainskaya VM, Chumakov SP, Moysenovich AM, Tereshchuk VM, Volkov DV, Pershin DS, Maksimov EG, Zhang H, Maschan MA, Rubtsov YP, Stepanov AV.
PMID: 34722633
Front Mol Biosci. 2021 Oct 13;8:745286. doi: 10.3389/fmolb.2021.745286. eCollection 2021.

CAR-T cell therapy is the most advanced way to treat therapy resistant hematologic cancers, in particular B cell lymphomas and leukemias, with high efficiency. Donor T cells equipped

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Kalinin RS, Ukrainskaya VM, Chumakov SP, et al. Engineered Removal of PD-1 From the Surface of CD19 CAR-T Cells Results in Increased Activation and Diminished Survival. Front Mol Biosci. 2021;8:745286doi: 10.3389/fmolb.2021.745286.
Kalinin, R. S., Ukrainskaya, V. M., Chumakov, S. P., Moysenovich, A. M., Tereshchuk, V. M., Volkov, D. V., Pershin, D. S., Maksimov, E. G., Zhang, H., Maschan, M. A., Rubtsov, Y. P., & Stepanov, A. V. (2021). Engineered Removal of PD-1 From the Surface of CD19 CAR-T Cells Results in Increased Activation and Diminished Survival. Frontiers in molecular biosciences, 8745286. https://doi.org/10.3389/fmolb.2021.745286
Kalinin, R S, et al. "Engineered Removal of PD-1 From the Surface of CD19 CAR-T Cells Results in Increased Activation and Diminished Survival." Frontiers in molecular biosciences vol. 8 (2021): 745286. doi: https://doi.org/10.3389/fmolb.2021.745286
Kalinin RS, Ukrainskaya VM, Chumakov SP, Moysenovich AM, Tereshchuk VM, Volkov DV, Pershin DS, Maksimov EG, Zhang H, Maschan MA, Rubtsov YP, Stepanov AV. Engineered Removal of PD-1 From the Surface of CD19 CAR-T Cells Results in Increased Activation and Diminished Survival. Front Mol Biosci. 2021 Oct 13;8:745286. doi: 10.3389/fmolb.2021.745286. eCollection 2021. PMID: 34722633; PMCID: PMC8548718.
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