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Correction: Discovery and clinical introduction of first-in-class imipridone ONC201.

Oncotarget

Allen JE, Kline CLB, Prabhu VV, Wagner J, Ishizawa J, Madhukar N, Lev A, Baumeister M, Zhou L, Lulla A, Stogniew M, Schalop L, Benes C, Kaufman HL, Pottorf RS, Nallaganchu BR, Olson GL, Al-Mulla F, Duvic M, Wu GS, Dicker DT, Talekar MK, Lim B, Elemento O, Oster W, Bertino J, Flaherty K, Wang ML, Borthakur G, Andreeff M, Stein M, El-Deiry WS.
PMID: 34676056
Oncotarget. 2021 Oct 12;12(21):2231. doi: 10.18632/oncotarget.28012. eCollection 2021 Oct 12.

[This corrects the article DOI: 10.18632/oncotarget.11814.].

Phase 2 Study of ONC201 in Neuroendocrine Tumors including Pheochromocytoma-Paraganglioma and Desmoplastic Small Round Cell Tumor.

Clinical cancer research : an official journal of the American Association for Cancer Research

Anderson PM, Trucco MM, Tarapore RS, Zahler S, Thomas S, Gortz J, Mian O, Stoignew M, Prabhu V, Morrow S, Allen JE.
PMID: 35022321
Clin Cancer Res. 2022 Jan 12; doi: 10.1158/1078-0432.CCR-21-4030. Epub 2022 Jan 12.

PURPOSE: Tumor dopamine-like DRD2 receptor expression is higher in pheochromocytoma-paraganglioma (PC-PG) compared to other cancers. ONC201 is a bitopic DRD2 antagonist with pre-clinical ONC201 activity in DSRCT.EXPERIMENTAL DESIGN: Patients (N=30) with neuroendocrine tumors were treated on this investigator-initiated trial...

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