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Showing 1 to 12 of 193 entries
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Visual analogue scales.

British journal of clinical pharmacology

Stubbs DF.
PMID: 760737
Br J Clin Pharmacol. 1979 Jan;7(1):124. doi: 10.1111/j.1365-2125.1979.tb00911.x.
Free PMC Article

No abstract available.

Scaling of events spaced in time.

Behavioural processes

Fetterman JG, Stubbs DA, Dreyfus LR.
PMID: 24924863
Behav Processes. 1986 Jun;13(1):53-68. doi: 10.1016/0376-6357(86)90016-1.

Pigeons were trained to peck on a key, which could be lit by red or green light, and produce feeder-light stimuli intermittently. On some trials, food followed the fourth feeder flash providing the key color was red, while on...

2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19.

ACS medicinal chemistry letters

Mallinger A, Schiemann K, Rink C, Sejberg J, Honey MA, Czodrowski P, Stubbs M, Poeschke O, Busch M, Schneider R, Schwarz D, Musil D, Burke R, Urbahns K, Workman P, Wienke D, Clarke PA, Raynaud FI, Eccles SA, Esdar C, Rohdich F, Blagg J.
PMID: 27326329
ACS Med Chem Lett. 2016 Mar 28;7(6):573-8. doi: 10.1021/acsmedchemlett.6b00022. eCollection 2016 Jun 09.

We demonstrate a designed scaffold-hop approach to the discovery of 2,8-disubstituted-1,6-naphthyridine- and 4,6-disubstituted-isoquinoline-based dual CDK8/19 ligands. Optimized compounds in both series exhibited rapid aldehyde oxidase-mediated metabolism, which could be abrogated by introduction of an amino substituent at C5 of...

Paraoesophageal splenosis: An unusual differential of mediastinal soft tissue deposits.

Journal of surgical case reports

Stubbs M, Aryal K, Thomas E.
PMID: 24960770
J Surg Case Rep. 2012 Aug 01;2012(8):12. doi: 10.1093/jscr/2012.8.12.

Ectopic splenic tissue can present as accessory spleens and splenosis. While accessory spleens are congenital and more common; splenosis occurs as a result of implantation of splenic tissue as a result of trauma or iatrogenic injury. Only up to...

Hip arthroscopy: a patient education and clinical research tool.

Journal of hip preservation surgery

Stone AV, Stubbs AJ.
PMID: 27011842
J Hip Preserv Surg. 2015 Jul;2(2):201. doi: 10.1093/jhps/hnv032. Epub 2015 May 16.

No abstract available.

Arthroscopic Bullet Removal From the Central and Peripheral Compartments of the Hip Joint.

Arthroscopy techniques

Howse EA, Rogers JP, Stone AV, Mannava S, Stubbs AJ.
PMID: 27489755
Arthrosc Tech. 2016 Mar 07;5(2):e217-21. doi: 10.1016/j.eats.2015.11.001. eCollection 2016 Apr.

Recent advances in hip arthroscopy offer an approach for treating an uncommon but highly disabling injury from intra-articular missile injury to the hip. Hip arthroscopy affords the patient the benefit of minimally invasive surgery while allowing for the diagnosis...

Basic Hip Arthroscopy: Anatomic Establishment of Arthroscopic Portals Without Fluoroscopic Guidance.

Arthroscopy techniques

Howse EA, Botros DB, Mannava S, Stone AV, Stubbs AJ.
PMID: 27489756
Arthrosc Tech. 2016 Mar 14;5(2):e247-50. doi: 10.1016/j.eats.2015.12.003. eCollection 2016 Apr.

Hip arthroscopy has gained popularity in recent years for diagnostic and therapeutic hip preservation management. This article details the establishment of arthroscopic portals of the hip, specifically the anterolateral and modified anterior portals without fluoroscopic guidance. The anterolateral portal...

Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase.

ACS infectious diseases

Batt SM, Cacho Izquierdo M, Castro Pichel J, Stubbs CJ, Vela-Glez Del Peral L, Pérez-Herrán E, Dhar N, Mouzon B, Rees M, Hutchinson JP, Young RJ, McKinney JD, Barros Aguirre D, Ballell L, Besra GS, Argyrou A.
PMID: 27623058
ACS Infect Dis. 2015 Dec 11;1(12):615-26. doi: 10.1021/acsinfecdis.5b00065. Epub 2015 Aug 25.

We have targeted the Mycobacterium tuberculosis decaprenylphosphoryl-β-d-ribose oxidase (Mt-DprE1) for potential chemotherapeutic intervention of tuberculosis. A multicopy suppression strategy that overexpressed Mt-DprE1 in M. bovis BCG was used to profile the publically available GlaxoSmithKline antimycobacterial compound set, and one...

Graph use in psychology and other sciences.

Behavioural processes

Best LA, Smith LD, Stubbs DA.
PMID: 11369467
Behav Processes. 2001 May 03;54(1):155-165. doi: 10.1016/s0376-6357(01)00156-5.

Since the early 19th century, graphs have been recognised as an effective method of analysing and representing scientific data. However, levels of graph use have varied widely since then, partly due to increasing reliance on inferential statistics in some...

Elucidating the vibrational spectra of hydrogen-bonded aggregates in solution: electronic structure calculations with implicit solvent and first-principles molecular dynamics simulations with explicit solvent for 1-hexanol in n-hexane.

Journal of the American Chemical Society

Stubbs JM, Siepmann JI.
PMID: 15796539
J Am Chem Soc. 2005 Apr 06;127(13):4722-9. doi: 10.1021/ja044380q.

Fourier transform infrared spectroscopy is a popular method for the experimental investigation of hydrogen-bonded aggregates, but linking spectral information to microscopic information on aggregate size distribution and aggregate architecture is an arduous task. Static electronic structure calculations with an...

Second-order schedules: comparison of different procedures for scheduling paired and nonpaired brief stimuli.

Journal of the experimental analysis of behavior

Stubbs DA, Cohen SL.
PMID: 16811634
J Exp Anal Behav. 1972 Nov;18(3):403-13. doi: 10.1901/jeab.1972.18-403.

Pigeons performed on a second-order schedule in which fixed-interval components were maintained under a variable-interval schedule. Completion of each fixed-interval component resulted in a brief-stimulus presentation and/or food. The relation of the brief stimulus and food was varied across...

Light echoes from ancient supernovae in the Large Magellanic Cloud.

Nature

Rest A, Suntzeff NB, Olsen K, Prieto JL, Smith RC, Welch DL, Becker A, Bergmann M, Clocchiatti A, Cook K, Garg A, Huber M, Miknaitis G, Minniti D, Nikolaev S, Stubbs C.
PMID: 16372003
Nature. 2005 Dec 22;438(7071):1132-4. doi: 10.1038/nature04365.

The light from historical supernovae could in principle still be visible as scattered-light echoes centuries after the explosion. The detection of light echoes could allow us to pinpoint the supernova event both in position and age and, most importantly,...

Showing 1 to 12 of 193 entries