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Evidence for the agricultural origin of resistance to multiple antimicrobials in Aspergillus fumigatus, a fungal pathogen of humans.

G3 (Bethesda, Md.)

Kang SE, Sumabat LG, Melie T, Mangum B, Momany M, Brewer MT.
PMID: 34897421
G3 (Bethesda). 2021 Dec 13; doi: 10.1093/g3journal/jkab427. Epub 2021 Dec 13.

Pathogen resistance to clinical antimicrobial agents is an urgent problem. The fungus Aspergillus fumigatus causes 300,000 life-threatening infections in susceptible humans annually. Azoles, which are widely used in both clinical and agricultural settings, are currently the most effective treatment,...

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