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Showing 1 to 12 of 188 entries
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Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.

Oncotarget

Dosch J, Ziemke E, Wan S, Luker K, Welling T, Hardiman K, Fearon E, Thomas S, Flynn M, Rios-Doria J, Hollingsworth R, Herbst R, Hurt E, Sebolt-Leopold J.
PMID: 29029414
Oncotarget. 2017 May 10;8(39):65090-65099. doi: 10.18632/oncotarget.17780. eCollection 2017 Sep 12.

ADAM17 (a disintegrin and metalloproteinase 17)/TACE (TNFα converting enzyme) has emerged as a potential therapeutic target in colorectal cancer (CRC) and other cancers, due in part to its role in regulating various tumor cell surface proteins and growth factors...

Epithelial cyst of the spleen with squamous metaplasia: a rare entity.

Journal of clinical and diagnostic research : JCDR

Shanthi V, Reddy VC, Rao NM, Grandhi B, Kona S.
PMID: 24959455
J Clin Diagn Res. 2014 Apr;8(4):FD05-6. doi: 10.7860/JCDR/2014/7795.4225. Epub 2014 Apr 15.

Epithelial splenic cysts are uncommon lesions which occur the spleen. The aetiopathogenesis of these cysts is not clear. We are reporting a case of an epithelial cyst which occurred in the spleen in a 40-year-old female, which was multi...

A rare case of primary malignant melanoma of clivus with extensive skeletal metastasis demonstrated on 18F-FDG PET/CT.

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

Dinesh SM, Suneetha B, Sen A.
PMID: 24379536
Indian J Nucl Med. 2013 Oct;28(4):234-6. doi: 10.4103/0972-3919.121971.

Malignant melanoma of the clivus is a rare entity, for which there is little evidence-based literature for guiding clinicians to understand the importance of disease staging via noninvasive imaging strategy. This report highlights the case of a 55-year-old lady...

Formulation and evaluation of transdermal drug delivery of topiramate.

International journal of pharmaceutical investigation

Cherukuri S, Batchu UR, Mandava K, Cherukuri V, Ganapuram KR.
PMID: 28405574
Int J Pharm Investig. 2017 Jan-Mar;7(1):10-17. doi: 10.4103/jphi.JPHI_35_16.

BACKGROUND: Transdermal drug delivery system (TDDS) was designed to sustain the release and improve the bioavailability of drug and patient compliance. Among the various types of transdermal patches, matrix dispersion type systems disperse the drug in the solvent along...

No Surgeon Is an Island.

JAMA surgery

Chazapis M, Ramani Moonesinghe S.
PMID: 27144732
JAMA Surg. 2016 Sep 01;151(9):882-3. doi: 10.1001/jamasurg.2016.0727.

No abstract available.

Antioxidant Activity of Passiflora edulis Sims Leaves.

Indian journal of pharmaceutical sciences

Sunitha M, Devaki K.
PMID: 20490300
Indian J Pharm Sci. 2009 May;71(3):310-1. doi: 10.4103/0250-474X.56038.

Ethanol extract of Passiflora edulis Sims was analyzed for its antioxidant (1,1-diphenyl-2-picryl hydrazyl radical reducing power methods) and phytochemical analysis. The extract was found effective against the antioxidant test models exhibiting an IC(50) value of 875+/-87.83 mug/ml and showed...

Disseminated cryptococcosis presenting with generalized lymphadenopathy.

Journal of cytology

Philip KJ, Kaur R, Sangeetha M, Masih K, Singh N, Mani A.
PMID: 23112464
J Cytol. 2012 Jul;29(3):200-2. doi: 10.4103/0970-9371.101175.

Cryptococcosis is a common opportunistic infection among immunocompromised individuals. Some of the commonly affected sites are respiratory and central nervous system. Lymph node is an unusual site of involvement which could mimic tuberculosis, as seen in our case. We...

Comparative study of oral and vaginal misoprostol for induction of labour, maternal and foetal outcome.

Journal of clinical and diagnostic research : JCDR

Komala K, Reddy M, Quadri IJ, B S, V R.
PMID: 24551660
J Clin Diagn Res. 2013 Dec;7(12):2866-9. doi: 10.7860/JCDR/2013/5825.3779. Epub 2013 Dec 15.

BACKGROUND: Misoprostol is a new promising agent for cervical ripening and induction of labour .The ideal dose, route and frequency of administration of misoprostol are still under investigation. Although, vaginal application of misoprostol has been validated as a reasonable...

Psychological distress in cardiac rehabilitation participants.

Journal of cardiopulmonary rehabilitation and prevention

Kolman L, Shin NM, Krishnan SM, Schwartz S, Gracik T, Jackson EA, Rubenfire M.
PMID: 21045712
J Cardiopulm Rehabil Prev. 2011 Mar-Apr;31(2):81-6. doi: 10.1097/HCR.0b013e3181f688e1.

PURPOSE: Limited data are available on the psychosocial characteristics of patients entering cardiac rehabilitation (CR). We characterized the psychological and clinical profiles of men and women entering CR to determine which, if any, characteristic identifies persons at high risk...

Salivaomics - A promising future in early diagnosis of dental diseases.

Dental research journal

Koneru S, Tanikonda R.
PMID: 24688554
Dent Res J (Isfahan). 2014 Jan;11(1):11-5.

Human saliva plays an important role in the health of the oral cavity and of the body as a whole. Salivary diagnostics is a dynamic and emerging field in the diagnosis of oral and systemic diseases. Saliva reflects the...

Diagnostic role of the antibody response to the 38kDa, 16kDa proteins and lipoarabinomannan of mycobacterium tuberculosis.

Indian journal of clinical biochemistry : IJCB

Raju R, Suneetha S, Sagili K, Meher VC, Saraswathi V, Satyanarayana AV, Suneetha LM.
PMID: 23105508
Indian J Clin Biochem. 2005 Jan;20(1):123-8. doi: 10.1007/BF02893056.

The antibody response to the 38kDa, 16kDa and Lipoarabinomannan (LAM) antigens ofMycobacterium tuberculosis was evaluated using three different ELISAs based on these antigens. The study group included tuberculosis patients (n=52), patients with HIV and TB co-infection (n=10), other chest...

Serum anti - TPO levels in benign and malignant breast tumors.

Indian journal of clinical biochemistry : IJCB

Sabitha, Suneetha, Mohanty S, Rao P.
PMID: 23105847
Indian J Clin Biochem. 2009 Jul;24(3):266-8. doi: 10.1007/s12291-009-0050-x. Epub 2009 Sep 16.

Breast cancer is a hormone dependent neoplasm. Conflicting results regarding the clinical correlation between breast cancer and thyroid diseases have been reported. The objective of this study was to determine the association of anti - TPO levels in patients...

Showing 1 to 12 of 188 entries