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Showing 1 to 11 of 11 entries
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"There was no panic"-Nurse managers' organising work for COVID-19 patients in an outpatient clinic: A qualitative study.

Journal of advanced nursing

Jónsdóttir H, Sverrisdóttir SH, Hafberg A, Ómarsdóttir G, Ragnarsdóttir ED, Ingvarsdóttir S, Ingadóttir B, Hafsteinsdóttir EJG, Zoëga S, Blöndal K.
PMID: 34931713
J Adv Nurs. 2021 Dec 21; doi: 10.1111/jan.15131. Epub 2021 Dec 21.

AIM: To provide insight into the contribution of nursing to the establishment and running of a hospital-based outpatient clinic for COVID-19 infected patients, and thereby to inform the development of similar nursing care and healthcare more generally.DESIGN: Qualitative descriptive...

Efficacy and Safety of Cabazitaxel Versus Abiraterone or Enzalutamide in Older Patients with Metastatic Castration-resistant Prostate Cancer in the CARD Study.

European urology

Sternberg CN, Castellano D, de Bono J, Fizazi K, Tombal B, Wülfing C, Kramer G, Eymard JC, Bamias A, Carles J, Iacovelli R, Melichar B, Sverrisdóttir Á, Theodore C, Feyerabend S, Helissey C, Poole EM, Ozatilgan A, Geffriaud-Ricouard C, de Wit R.
PMID: 34274136
Eur Urol. 2021 Oct;80(4):497-506. doi: 10.1016/j.eururo.2021.06.021. Epub 2021 Jul 15.

BACKGROUND: In the CARD study (NCT02485691), cabazitaxel significantly improved median radiographic progression-free survival (rPFS) and overall survival (OS) versus abiraterone/enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC) who had previously received docetaxel and progressed ≤12 mo on the...

Incident adverse drug reactions in geriatric inpatients: a multicentred observational study.

Therapeutic advances in drug safety

Lavan A, Eustace J, Dahly D, Flanagan E, Gallagher P, Cullinane S, Petrovic M, Perehudoff K, Gudmondsson A, Samuelsson Ó, Sverrisdóttir Á, Cherubin A, Dimitri F, Rimland J, Cruz-Jentoft A, Vélez-Díaz-Pallarés M, Lozano Montoya I, Soiza RL, Subbarayan S, O'Mahony D.
PMID: 29318003
Ther Adv Drug Saf. 2018 Jan;9(1):13-23. doi: 10.1177/2042098617736191. Epub 2017 Oct 24.

BACKGROUND: Adverse drug reactions (ADRs) are common in older adults and frequently have serious clinical and economic consequences. This study was conducted as a feasibility study for a randomized control trial (RCT) that will investigate the efficacy of a...

A single-centre investigator-blinded randomised parallel-group study protocol to investigate the influence of an acclimatisation appointment on children's behaviour during N.

BDJ open

Kowash M, Al-Halabi M, Hussein I, Abdo MM, Salami A, Hassan A, Sverrisdottir Y, Tahmassebi JF.
PMID: 32194987
BDJ Open. 2020 Mar 17;6:5. doi: 10.1038/s41405-020-0031-y. eCollection 2020.

AIMS AND OBJECTIVES: To describe a study protocol of a randomised control trial (RCT) assessing the effectiveness, in reducing dental anxiety, of an acclimatising nitrous oxide sedation (NMATERIALS AND METHODS: A single-centre investigator-blinded parallel-group RCT conducted in a postgraduate...

The Value of Expanding the Training Population to Improve Genomic Selection Models in Tetraploid Potato.

Frontiers in plant science

Sverrisdóttir E, Sundmark EHR, Johnsen HØ, Kirk HG, Asp T, Janss L, Bryan G, Nielsen KL.
PMID: 30131817
Front Plant Sci. 2018 Aug 06;9:1118. doi: 10.3389/fpls.2018.01118. eCollection 2018.

Genomic selection (GS) is becoming increasingly applicable to crops as the genotyping costs continue to decrease, which makes it an attractive alternative to traditional selective breeding based on observed phenotypes. With genome-wide molecular markers, selection based on predictions from...

Human Dorsal Root Ganglion Stimulation Reduces Sympathetic Outflow and Long-Term Blood Pressure.

JACC. Basic to translational science

Sverrisdottir YB, Martin SC, Hadjipavlou G, Kent AR, Paterson DJ, FitzGerald JJ, Green AL.
PMID: 33145461
JACC Basic Transl Sci. 2020 Sep 16;5(10):973-985. doi: 10.1016/j.jacbts.2020.07.010. eCollection 2020 Oct.

This study hypothesized that dorsal root ganglion (DRG) stimulation would reduce sympathetic nerve activity and would alter hemodynamic variables. This study directly recorded muscle sympathetic nerve activity during ON and OFF stimulation of the DRG while measuring hemodynamic parameters....

The PHARMACOM-EPI Framework for Integrating Pharmacometric Modelling Into Pharmacoepidemiological Research Using Real-World Data: Application to Assess Death Associated With Valproate.

Clinical pharmacology and therapeutics

Soeorg H, Sverrisdóttir E, Andersen M, Lund TM, Sessa M.
PMID: 34860420
Clin Pharmacol Ther. 2021 Dec 03; doi: 10.1002/cpt.2502. Epub 2021 Dec 03.

In pharmacoepidemiology, it is usually expected that the observed association should be directly or indirectly related to the pharmacological effects of the drug/s under investigation. Pharmacological effects are, in turn, strongly connected to the pharmacokinetic and pharmacodynamic properties of...

The PHARMACOM-EPI framework for integrating pharmacometric modelling into pharmacoepidemiological research using real-world data: application to assess death associated with valproate.

Clinical pharmacology and therapeutics

Soeorg H, Sverrisdóttir E, Andersen M, Lund TM, Sessa M.
PMID: 34860420
Clin Pharmacol Ther. 2021 Dec 03; doi: 10.1002/cpt.2502. Epub 2021 Dec 03.

In pharmacoepidemiology, it is usually expected that the observed association should be directly or indirectly related to the pharmacological effects of the drug/s under investigation. Pharmacological effects are, in turn, strongly connected to the pharmacokinetic and pharmacodynamic properties of...

Sensitivity of quantitative sensory models to morphine analgesia in humans.

Journal of pain research

Olesen AE, Brock C, Sverrisdóttir E, Larsen IM, Drewes AM.
PMID: 25525384
J Pain Res. 2014 Dec 09;7:717-26. doi: 10.2147/JPR.S73044. eCollection 2014.

INTRODUCTION: Opioid analgesia can be explored with quantitative sensory testing, but most investigations have used models of phasic pain, and such brief stimuli may be limited in the ability to faithfully simulate natural and clinical painful experiences. Therefore, identification...

High-Intensity Interval Training Decreases Muscle Sympathetic Nerve Activity in Men With Essential Hypertension and in Normotensive Controls.

Frontiers in neuroscience

Ehlers TS, Sverrisdottir Y, Bangsbo J, Gunnarsson TP.
PMID: 33013285
Front Neurosci. 2020 Aug 18;14:841. doi: 10.3389/fnins.2020.00841. eCollection 2020.

Exercise training is a cornerstone in reducing blood pressure (BP) and muscle sympathetic nerve activity (MSNA) in individuals with essential hypertension. High-intensity interval training (HIIT) has been shown to be a time efficient alternative to classical continuous training in...

Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative.

Cancer discovery

Aftimos P, Oliveira M, Irrthum A, Fumagalli D, Sotiriou C, Gal-Yam EN, Robson ME, Ndozeng J, Di Leo A, Ciruelos EM, de Azambuja E, Viale G, Scheepers ED, Curigliano G, Bliss JM, Reis-Filho JS, Colleoni M, Balic M, Cardoso F, Albanell J, Duhem C, Marreaud S, Romagnoli D, Rojas B, Gombos A, Wildiers H, Guerrero-Zotano A, Hall P, Bonetti A, Larsson KF, Degiorgis M, Khodaverdi S, Greil R, Sverrisdóttir Á, Paoli M, Seyll E, Loibl S, Linderholm B, Zoppoli G, Davidson NE, Johannsson OT, Bedard PL, Loi S, Knox S, Cameron DA, Harbeck N, Montoya ML, Brandão M, Vingiani A, Caballero C, Hilbers FS, Yates LR, Benelli M, Venet D, Piccart MJ.
PMID: 34183353
Cancer Discov. 2021 Nov;11(11):2796-2811. doi: 10.1158/2159-8290.CD-20-1647. Epub 2021 Jun 28.

AURORA aims to study the processes of relapse in metastatic breast cancer (MBC) by performing multi-omics profiling on paired primary tumors and early-course metastases. Among 381 patients (primary tumor and metastasis pairs: 252 targeted gene sequencing, 152 RNA sequencing,...

Showing 1 to 11 of 11 entries