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Showing 1 to 12 of 12 entries
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In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME.
PMID: 34370182
Clin Transl Oncol. 2022 Jan;24(1):127-144. doi: 10.1007/s12094-021-02677-8. Epub 2021 Aug 09.

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translational tool and physiologically relevant system to...

Disease Modeling with 3D Cell-Based Assays Using a Novel Flowchip System and High-Content Imaging.

SLAS technology

Cromwell EF, Leung M, Hammer M, Thai A, Rajendra R, Sirenko O.
PMID: 33783259
SLAS Technol. 2021 Jun;26(3):237-248. doi: 10.1177/24726303211000688. Epub 2021 Mar 30.

There is an increasing interest in using three-dimensional (3D) cell structures for modeling tumors, organs, and tissue to accelerate translational research. We describe here a novel automated organoid assay system (the Pu·MA System) combined with microfluidic-based flowchips that can...

In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME.
PMID: 34370182
Clin Transl Oncol. 2021 Aug 09; doi: 10.1007/s12094-021-02677-8. Epub 2021 Aug 09.

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translational tool and physiologically relevant system to...

Chromatographic profiles and antimicrobial activity of the essential oils obtained from some species and cultivars of the .

Saudi journal of biological sciences

Shanaida M, Hudz N, Białoń M, Kryvtsowa M, Svydenko L, Filipska A, Paweł Wieczorek P.
PMID: 34759738
Saudi J Biol Sci. 2021 Nov;28(11):6145-6152. doi: 10.1016/j.sjbs.2021.06.068. Epub 2021 Jun 26.

The present study was focused on the chemical composition and antimicrobial activity of the essential oils (EsO) obtained from five

In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME.
PMID: 34370182
Clin Transl Oncol. 2022 Jan;24(1):127-144. doi: 10.1007/s12094-021-02677-8. Epub 2021 Aug 09.

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translational tool and physiologically relevant system to...

In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME.
PMID: 34370182
Clin Transl Oncol. 2022 Jan;24(1):127-144. doi: 10.1007/s12094-021-02677-8. Epub 2021 Aug 09.

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translational tool and physiologically relevant system to...

A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.

Green chemistry : an international journal and green chemistry resource : GC

Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde AM, Rusyn I.
PMID: 28035192
Green Chem. 2016 Aug 21;18(16):4407-4419. doi: 10.1039/c6gc01147k. Epub 2016 May 16.

Comparative assessment of potential human health impacts is a critical step in evaluating both chemical alternatives and existing products on the market. Most alternatives assessments are conducted on a chemical-by-chemical basis and it is seldom acknowledged that humans are...

Time-and-frequency domains approach to data processing in multiwavelength optical scatterometry of dielectric gratings.

Journal of the Optical Society of America. A, Optics, image science, and vision

Granet G, Melezhik P, Sirenko K, Yashina N.
PMID: 23456118
J Opt Soc Am A Opt Image Sci Vis. 2013 Mar 01;30(3):427-36. doi: 10.1364/JOSAA.30.000427.

This paper focuses on scatterometry problems arising in lithography production of periodic gratings. Namely, the paper introduces a theoretical and numerical-modeling-oriented approach to scatterometry problems and discusses its capabilities. The approach allows for reliable detection of deviations in gratings'...

Continuation of the ESH-CHL-SHOT trial after publication of the SPRINT: rationale for further study on blood pressure targets of antihypertensive treatment after stroke.

Journal of hypertension

Zanchetti A, Liu L, Mancia G, Parati G, Grassi G, Stramba-Badiale M, Silani V, Bilo G, Corrao G, Zambon A, Scotti L, Zhang X, Guan TR, Zhang Y, Zhang X, Berge E, Redon J, Narkiewicz K, Dominiczak A, Nilsson P, Viigimaa M, Laurent S, Agabiti-Rosei E, Wu Z, Zhu D, Rodicio JL, Ruilope LM, Martell-Claros N, Pinto F, Schmieder RE, Burnier M, Banach M, Cifkova R, Farsang C, Konradi A, Lazareva I, Sirenko Y, Dorobantu M, Postadzhiyan A, Accetto R, Jelakovic B, Lovic D, Manolis AJ, Stylianou P, Dicker D, Wei G, Xu C, Xie H, Coca A, O'Brien J, Ford G.
PMID: 26780185
J Hypertens. 2016 Mar;34(3):393-6. doi: 10.1097/HJH.0000000000000853.

No abstract available.

Efficient discontinuous Galerkin scheme for analyzing nanostructured photoconductive devices.

Optics express

Chen L, Sirenko K, Li P, Bagci H.
PMID: 33985036
Opt Express. 2021 Apr 26;29(9):12903-12917. doi: 10.1364/OE.422619.

Incorporation of plasmonic nanostructures in the design of photoconductive devices (PCDs) has significantly improved their optical-to-terahertz conversion efficiency. However, this improvement comes at the cost of increased complexity for the design and simulation of these devices. Indeed, accurate and...

Modifying effects of .

Drug metabolism and personalized therapy

Fishchuk L, Rossokha Z, Pokhylko V, Cherniavska Y, Tsvirenko S, Kovtun S, Medvedieva N, Vershyhora V, Gorovenko N.
PMID: 34860474
Drug Metab Pers Ther. 2021 Dec 06; doi: 10.1515/dmpt-2021-0127. Epub 2021 Dec 06.

OBJECTIVES: COVID-19 continues to range around the world and set morbidity and mortality antirecords. Determining the role of genetic factors in the development of COVID-19 may contribute to the understanding of the pathogenetic mechanisms that lead to the development...

In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME.
PMID: 34370182
Clin Transl Oncol. 2022 Jan;24(1):127-144. doi: 10.1007/s12094-021-02677-8. Epub 2021 Aug 09.

Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse molecular and histological heterogeneity. Patient-derived xenografts (PDXs) provide a translational tool and physiologically relevant system to...

Showing 1 to 12 of 12 entries