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Showing 1 to 12 of 43 entries
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Historeceptomic Fingerprints for Drug-Like Compounds.

Frontiers in physiology

Shmelkov E, Grigoryan A, Swetnam J, Xin J, Tivon D, Shmelkov SV, Cardozo T.
PMID: 26733872
Front Physiol. 2015 Dec 18;6:371. doi: 10.3389/fphys.2015.00371. eCollection 2015.

Most drugs exert their beneficial and adverse effects through their combined action on several different molecular targets (polypharmacology). The true molecular fingerprint of the direct action of a drug has two components: the ensemble of all the receptors upon...

Improved electronic coupling in hybrid organic-inorganic nanocomposites employing thiol-functionalized P3HT and bismuth sulfide nanocrystals.

Nanoscale

Martinez L, Higuchi S, MacLachlan AJ, Stavrinadis A, Miller NC, Diedenhofen SL, Bernechea M, Sweetnam S, Nelson J, Haque SA, Tajima K, Konstantatos G.
PMID: 25029606
Nanoscale. 2014 Sep 07;6(17):10018-26. doi: 10.1039/c4nr01679c.

In this study, we employ a thiol-functionalized polymer (P3HT-SH) as a leverage to tailor the nanomorphology and electronic coupling in polymer-nanocrystal composites for hybrid solar cells. The presence of the thiol functional group allows for a highly crystalline semiconducting...

Royal Medical Benevolent Fund reminds readers of its Christmas appeal.

Clinical radiology

Sweetnam R.
PMID: 11124084
Clin Radiol. 2000 Dec;55(12):983. doi: 10.1053/crad.2000.0611.

No abstract available.

Banti's Syndrome in Siblings Treated by Porta-caval Anastomosis (Two cases).

Proceedings of the Royal Society of Medicine

Sweetnam WP.
PMID: 19993871
Proc R Soc Med. 1955 Dec;48(12):1108.

No abstract available.

Light trapping to amplify metal enhanced fluorescence with application for sensing TNT.

Journal of fluorescence

Matoian MA, Sweetman R, Hall EC, Albanese S, Euler WB.
PMID: 23666028
J Fluoresc. 2013 Sep;23(5):877-80. doi: 10.1007/s10895-013-1232-8. Epub 2013 May 11.

Metal Enhanced Fluorescence (MEF) typically produces enhancement factors of 10 to 50. By using a polymer layer as the dielectric spacer enhancements as high as 1,600 can be observed. The effect occurs with a variety of different polymers and...

The Friends of Cancer Research Real-World Data Collaboration Pilot 2.0: Methodological Recommendations from Oncology Case Studies.

Clinical pharmacology and therapeutics

Rivera DR, Henk HJ, Garrett-Mayer E, Christian JB, Belli AJ, Bruinooge SS, Espirito JL, Sweetnam C, Izano MA, Natanzon Y, Robert NJ, Walker MS, Cohen AB, Boyd M, Enewold L, Hansen E, Honnold R, Kushi L, Mishra Kalyani PS, Pe Benito R, Sakoda LC, Sharon E, Tymejczyk O, Valice E, Wagner J, Lasiter L, Allen JD.
PMID: 34664259
Clin Pharmacol Ther. 2022 Jan;111(1):283-292. doi: 10.1002/cpt.2453. Epub 2021 Nov 11.

The purpose of this study was to evaluate the potential collective opportunities and challenges of transforming real-world data (RWD) to real-world evidence for clinical effectiveness by focusing on aligning analytic definitions of oncology end points. Patients treated with a...

A retrospective cohort study of clinical factors, visit patterns, and demographic factors associated with use of remote communications in patients with headache.

Headache

Mueller B, Sweetnam C, Klenofsky B, Pace A, Grant J, Natbony L, Robinson-Papp J, Kummer B.
PMID: 34713896
Headache. 2021 Oct 29; doi: 10.1111/head.14226. Epub 2021 Oct 29.

OBJECTIVE: To identify the characteristics associated with high utilization of remote communications (RCs) in patients with headache.BACKGROUND: Patients with headache frequently communicate with their providers using secure portal messaging and telephone calls. However, clinical and demographic factors as well...

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.

bioRxiv : the preprint server for biology

Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD.
PMID: 32869021
bioRxiv. 2020 Aug 26; doi: 10.1101/2020.08.26.268854.

SARS-CoV-2 has resulted in a global pandemic and shutdown economies around the world. Sequence analysis indicates that the novel coronavirus (CoV) has an insertion of a furin cleavage site (PRRAR) in its spike protein. Absent in other group 2B...

Ten simple rules to cultivate transdisciplinary collaboration in data science.

PLoS computational biology

Sahneh F, Balk MA, Kisley M, Chan CK, Fox M, Nord B, Lyons E, Swetnam T, Huppenkothen D, Sutherland W, Walls RL, Quinn DP, Tarin T, LeBauer D, Ribes D, Birnie DP, Lushbough C, Carr E, Nearing G, Fischer J, Tyle K, Carrasco L, Lang M, Rose PW, Rushforth RR, Roy S, Matheson T, Lee T, Brown CT, Teal TK, Papeș M, Kobourov S, Merchant N.
PMID: 33983959
PLoS Comput Biol. 2021 May 13;17(5):e1008879. doi: 10.1371/journal.pcbi.1008879. eCollection 2021 May.

No abstract available.

Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants.

bioRxiv : the preprint server for biology

Jaworski E, Langsjoen RM, Mitchell B, Judy B, Newman P, Plante JA, Plante KS, Miller AL, Zhou Y, Swetnam D, Sotcheff S, Morris V, Saada N, Machado R, McConnell A, Widen S, Thompson J, Dong J, Ren P, Pyles RB, Ksiazek T, Menachery VD, Weaver SC, Routh A.
PMID: 33758846
bioRxiv. 2021 Mar 11; doi: 10.1101/2021.03.10.434828.

High-throughput genomics of SARS-CoV-2 is essential to characterize virus evolution and to identify adaptations that affect pathogenicity or transmission. While single-nucleotide variations (SNVs) are commonly considered as driving virus adaption, RNA recombination events that delete or insert nucleic acid...

Royal Medical Benevolent Fund reminds readers of its Christmas appeal.

BMJ (Clinical research ed.)

Sweetnam R.
PMID: 10567158
BMJ. 1999 Nov 20;319(7221):1369. doi: 10.1136/bmj.319.7221.1369.

No abstract available.

Congenital fibrosis of the liver as a familial defect.

Lancet (London, England)

SWEETNAM WP, SYKES CG.
PMID: 13774271
Lancet. 1961 Feb 18;1(7173):374-6. doi: 10.1016/s0140-6736(61)91539-2.

No abstract available.

Showing 1 to 12 of 43 entries