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Determination of oxidative stress and activities of antioxidant enzymes in guinea pigs treated with haloperidol.

Experimental and therapeutic medicine

Gumulec J, Raudenska M, Hlavna M, Stracina T, Sztalmachova M, Tanhauserova V, Pacal L, Ruttkay-Nedecky B, Sochor J, Zitka O, Babula P, Adam V, Kizek R, Novakova M, Masarik M.
PMID: 23403848
Exp Ther Med. 2013 Feb;5(2):479-484. doi: 10.3892/etm.2012.822. Epub 2012 Nov 20.

Guinea pigs (Cavia porcellus) were treated with haloperidol (HP), and free radical (FR) and ferric reducing antioxidant power (FRAP) assays were used to determine oxidative stress levels. Furthermore, the superoxide dismutase (SOD), glutathione reductase (GR) and glutathione-S-transferase (GST) activity...

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