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Showing 1 to 12 of 26 entries
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SBRT to adrenal metastases provides high local control with minimal toxicity.

Advances in radiation oncology

Plichta K, Camden N, Furqan M, Hejleh TA, Clamon GH, Zhang J, Flynn RT, Bhatia SK, Smith MC, Buatti JM, Allen BG.
PMID: 29204525
Adv Radiat Oncol. 2017 Aug 04;2(4):581-587. doi: 10.1016/j.adro.2017.07.011. eCollection 2017.

PURPOSE: The adrenal glands are a common site of metastases because of their rich blood supply. Previously, adrenal metastases were treated with systemic chemotherapy or, more rarely, with surgical resection or palliative radiation therapy. Stereotactic body radiation therapy (SBRT)...

O.

Cancer cell

Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, Monga V, Bodeker KL, Ahmann L, Vollstedt S, Brown H, Kauffman EPS, Schall ME, Hohl RJ, Clamon GH, Greenlee JD, Howard MA, Schultz MK, Smith BJ, Riley DP, Domann FE, Cullen JJ, Buettner GR, Buatti JM, Spitz DR, Allen BG.
PMID: 28810149
Cancer Cell. 2017 Aug 14;32(2):268. doi: 10.1016/j.ccell.2017.07.008.

No abstract available.

Isolation and culture of adult murine cardiac atrial and ventricular fibroblasts and myofibroblasts.

Methods (San Diego, Calif.)

Sahadevan P, Allen BG.
PMID: 33838270
Methods. 2021 Apr 08; doi: 10.1016/j.ymeth.2021.04.004. Epub 2021 Apr 08.

Cardiac fibroblasts play a critical role in extracellular matrix homeostasis, wound healing, and cardiac interstitial fibrosis: the latter being a pathophysiological response to a chronic increase in afterload. Using a standard protocol to isolate cardiac fibroblasts and maintain them...

Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma.

Frontiers in oncology

Seyedin SN, Gannon MK, Plichta KA, Abushahin L, Berg DJ, Arshava EV, Parekh KR, Keech JC, Caster JM, Welsh JW, Allen BG.
PMID: 32850412
Front Oncol. 2020 Jul 31;10:1311. doi: 10.3389/fonc.2020.01311. eCollection 2020.

No abstract available.

Lobar versus sub-lobar surgery for pulmonary typical carcinoid, a population-based analysis.

Journal of thoracic disease

Furqan M, Tien YY, Schroeder MC, Parekh KR, Keech J, Allen BG, Thomas A, Zhang J, Clamon G, Abu Hejleh T.
PMID: 30505493
J Thorac Dis. 2018 Oct;10(10):5850-5859. doi: 10.21037/jtd.2018.09.141.

BACKGROUND: The optimal surgery for resectable pulmonary typical carcinoid (TC), e.g., lobar resection (L-R) METHODS: The Surveillance, Epidemiology, and End Results (SEER) Program was used to select patients ≥66 years old, and diagnosed between 2000 and 2012 with pulmonary...

Neoadjuvant Radiotherapy-Related Wound Morbidity in Soft Tissue Sarcoma: Perspectives for Radioprotective Agents.

Cancers

Callaghan CM, Hasibuzzaman MM, Rodman SN, Goetz JE, Mapuskar KA, Petronek MS, Steinbach EJ, Miller BJ, Pulliam CF, Coleman MC, Monga VV, Milhem MM, Spitz DR, Allen BG.
PMID: 32806601
Cancers (Basel). 2020 Aug 12;12(8). doi: 10.3390/cancers12082258.

Historically, patients with localized soft tissue sarcomas (STS) of the extremities would undergo limb amputation. It was subsequently determined that the addition of radiation therapy (RT) delivered prior to (neoadjuvant) or after (adjuvant) a limb-sparing surgical resection yielded equivalent...

Iron-Sulfur Cluster Biogenesis as a Critical Target in Cancer.

Antioxidants (Basel, Switzerland)

Petronek MS, Spitz DR, Allen BG.
PMID: 34573089
Antioxidants (Basel). 2021 Sep 14;10(9). doi: 10.3390/antiox10091458.

Cancer cells preferentially accumulate iron (Fe) relative to non-malignant cells; however, the underlying rationale remains elusive. Iron-sulfur (Fe-S) clusters are critical cofactors that aid in a wide variety of cellular functions (e.g., DNA metabolism and electron transport). In this...

Quantum chemical insight into the effects of the local electron environment on T.

Scientific reports

Petronek MS, St-Aubin JJ, Lee CY, Spitz DR, Gillan EG, Allen BG, Magnotta VA.
PMID: 34675308
Sci Rep. 2021 Oct 21;11(1):20817. doi: 10.1038/s41598-021-00305-7.

T

Modulation of 5-fluorouracil in the adjuvant setting: high-dose, low-dose or no-dose leucovorin?.

Nature clinical practice. Oncology

Taal BG, Cats A, van Tinteren H.
PMID: 16757967
Nat Clin Pract Oncol. 2006 Jun;3(6):300-1. doi: 10.1038/ncponc0515.

No abstract available.

Cloning, expression and purification of functionally active human angiopoietin-like protein 2.

SpringerPlus

Farhat N, Mamarbachi AM, Thorin E, Allen BG.
PMID: 25077060
Springerplus. 2014 Jul 03;3:337. doi: 10.1186/2193-1801-3-337. eCollection 2014.

Angiopoietin-like protein 2 (Angptl2) is a secreted glycoprotein that has been implicated in angiogenesis, inflammation and atherosclerosis as well as enhancing the survival of human hematopoietic stem cells. Glycosylation of Angptl2 is required for biological activity and studies of...

Once Daily High-dose Radiation (≥60 Gy) Treatment in Limited Stage Small Cell Lung Cancer.

Journal of oncology translational research

Zahra A, Chang T, Hejleh TA, Furqan M, Clamon GH, Bhatia SK, Watkins JM, Mott SL, Ahmann LL, Bodeker KL, Spitz DR, Buatti JM, Allen BG.
PMID: 27981260
J Oncol Transl Res. 2016 Nov;2(1). Epub 2016 Jul 26.

BACKGROUND: To investigate outcomes and prognostic factors in patients treated with once daily high-dose (≥60 Gy) radiation therapy (HDRT) and concurrent platinum-based chemotherapy in limited stage small cell lung cancer (LS-SCLC). While we await current phase III trials to...

A Single-Institution Analysis of Thymic Carcinoma Treated with Multi-Modality Therapy.

Annals of radiation therapy and oncology

Mohiuddin IH, Furqan M, Clamon G, Keech J, Anderson C, Smith MC, Buatti JM, Allen BG.
PMID: 30148284
Ann Radiat Ther Oncol. 2017;1(3). Epub 2017 Nov 22.

PURPOSE: Review of our experience in treating thymic carcinoma patients using a combination of surgery, chemotherapy and radiation therapy.METHODS: An institutional review of thymic carcinoma patients treated between 2007 and 2014 was performed analyzing clinical characteristics, treatment intent, surgical...

Showing 1 to 12 of 26 entries