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Showing 1 to 12 of 82 entries
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The clinical research mission of dental colleges.

Dental journal

Taintor JF, Biesterfeld RC.
PMID: 283014
Dent J. 1979 Jan;45(1):26-7.

No abstract available.

Beginning and continuing.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

Taintor Z.
PMID: 24442970
Acad Psychiatry. 1989 Mar;13(1):1-2. doi: 10.1007/BF03341834.

No abstract available.

Putting the brakes on CTLA-4 inhibition in lung cancer?.

Translational lung cancer research

Mooradian MJ, Gainor JF.
PMID: 29531902
Transl Lung Cancer Res. 2018 Feb;7:S35-S38. doi: 10.21037/tlcr.2018.01.05.

No abstract available.

Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer.

Cancer cell

Naranbhai V, St Denis KJ, Lam EC, Ofoman O, Garcia-Beltran WF, Mairena CB, Bhan AK, Gainor JF, Balazs AB, Iafrate AJ.
PMID: 34990570
Cancer Cell. 2022 Jan 10;40(1):103-108.e2. doi: 10.1016/j.ccell.2021.12.002. Epub 2022 Jan 05.

Patients with cancer are more likely to have impaired immune responses to SARS-CoV-2 vaccines. We study the breadth of responses against SARS-CoV-2 variants after primary vaccination in 178 patients with a variety of tumor types and after booster doses...

Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer.

Cancer cell

Naranbhai V, St Denis KJ, Lam EC, Ofoman O, Garcia-Beltran WF, Mairena CB, Bhan AK, Gainor JF, Balazs AB, Iafrate AJ.
PMID: 34990570
Cancer Cell. 2022 Jan 10;40(1):103-108.e2. doi: 10.1016/j.ccell.2021.12.002. Epub 2022 Jan 05.

Patients with cancer are more likely to have impaired immune responses to SARS-CoV-2 vaccines. We study the breadth of responses against SARS-CoV-2 variants after primary vaccination in 178 patients with a variety of tumor types and after booster doses...

Intracranial Efficacy of Selpercatinib in .

Clinical cancer research : an official journal of the American Association for Cancer Research

Subbiah V, Gainor JF, Oxnard GR, Tan DSW, Owen DH, Cho BC, Loong HH, McCoach CE, Weiss J, Kim YJ, Bazhenova L, Park K, Daga H, Besse B, Gautschi O, Rolfo C, Zhu EY, Kherani JF, Huang X, Kang S, Drilon A.
PMID: 34088726
Clin Cancer Res. 2021 Aug 01;27(15):4160-4167. doi: 10.1158/1078-0432.CCR-21-0800. Epub 2021 Jun 04.

PURPOSE: We report the intracranial efficacy of selpercatinib, a highly potent and selective RET inhibitor, approved in the United States for PATIENTS AND METHODS: In the global phase 1/2 LIBRETTO-001 trial (NCT03157128) in advanced RESULTS: Eighty patients with NSCLC...

Dexamethasone intravitreal implant in treatment-naïve diabetic macular oedema: findings from the prospective, multicentre, AUSSIEDEX study.

The British journal of ophthalmology

Fraser-Bell S, Kang HK, Mitchell P, Arnold JJ, Tainton J, Simonyi S.
PMID: 34433549
Br J Ophthalmol. 2021 Aug 25; doi: 10.1136/bjophthalmol-2021-319070. Epub 2021 Aug 25.

AIM: To evaluate the effectiveness of dexamethasone intravitreal implant 0.7 mg (DEX; Ozurdex) monotherapy in the patient subgroup of the AUSSIEDEX study with treatment-naïve diabetic macular oedema (DME).METHODS: The open-label, prospective, phase 4, real-world study included pseudophakic eyes and...

Heterogeneous immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Bowes CL, Naranbhai V, St Denis KJ, Lam EC, Bertaux B, Keane FK, Khandekar MJ, Balazs AB, Iafrate JA, Gainor JF, Willers H.
PMID: 34838892
Radiother Oncol. 2021 Nov 25;166:88-91. doi: 10.1016/j.radonc.2021.11.012. Epub 2021 Nov 25.

The immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy is unknown. This prospective cohort study demonstrates that anti-SARS-CoV-2 spike antibody and neutralization titers are reduced in a subset of thoracic radiotherapy patients, possibly due to immunosuppressive conditions. Antibody...

Lymphocyte-activation gene 3 in non-small-cell lung carcinomas: correlations with clinicopathologic features and prognostic significance.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Shepherd DJ, Tabb ES, Kunitoki K, Zhang ML, Kem M, Barth J, Qualls DA, Mooradian MJ, Gainor JF, Mino-Kenudson M, Hung YP.
PMID: 34880448
Mod Pathol. 2021 Dec 08; doi: 10.1038/s41379-021-00974-9. Epub 2021 Dec 08.

Lymphocyte-activation gene 3 (LAG-3) modulates the tumor microenvironment through immunosuppressive effects. Its associations with clinicopathologic parameters and prognostic significance in non-small-cell lung carcinomas remain unclear. We examined LAG-3 expression in 368 resected non-small-cell lung carcinomas (including 218 adenocarcinomas and...

Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer.

Cancer cell

Naranbhai V, St Denis KJ, Lam EC, Ofoman O, Garcia-Beltran WF, Mairena CB, Bhan AK, Gainor JF, Balazs AB, Iafrate AJ.
PMID: 34990570
Cancer Cell. 2022 Jan 05; doi: 10.1016/j.ccell.2021.12.002. Epub 2022 Jan 05.

Patients with cancer are more likely to have impaired immune responses to SARS-CoV-2 vaccines. We study the breadth of responses against SARS-CoV-2 variants after primary vaccination in 178 patients with a variety of tumor types and after booster doses...

Safety and activity of alectinib plus bevacizumab in patients with advanced ALK-rearranged non-small-cell lung cancer: a phase I/II study.

ESMO open

Lin JJ, Muzikansky A, Kennedy E, Kuberski H, Stober LL, Wanat AC, Azzoli CG, Lennes I, Sequist LV, Dagogo-Jack I, Shaw AT, Gainor JF.
PMID: 34896762
ESMO Open. 2021 Dec 09;7(1):100342. doi: 10.1016/j.esmoop.2021.100342. Epub 2021 Dec 09.

BACKGROUND: Alectinib, a second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI), is highly effective in advanced ALK-rearranged non-small-cell lung cancer and represents a standard first-line therapy. New strategies are needed, however, to delay resistance. We conducted a phase...

Energy, transport, and consumption in the Industrial Revolution.

The Behavioral and brain sciences

Tainter JA, Taylor TG.
PMID: 31744564
Behav Brain Sci. 2019 Nov 20;42:e209. doi: 10.1017/S0140525X19000153.

We question Baumard's underlying assumption that humans have a propensity to innovate. Affordable transportation and energy underpinned the Industrial Revolution, making mass production/consumption possible. Although we cannot accept Baumard's thesis on the Industrial Revolution, it may help explain why...

Showing 1 to 12 of 82 entries