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Showing 1 to 12 of 640 entries
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Population statistics and biological traits of endangered kiso horse.

Journal of equine science

Takasu M, Hiramatsu N, Tozaki T, Kakoi H, Hasegawa T, Maeda M, Kusuda S, Doi O, Murase T, Mukoyama H.
PMID: 24833989
J Equine Sci. 2011;22(4):67-72. doi: 10.1294/jes.22.67. Epub 2012 Feb 28.

The objective of this study was to clarify the current status of endangered Kiso horse, population statistics and biological traits, in order to take a step for the conservation by scientific approach. We surveyed 125 Kiso horses (86.2% of...

Hematological and biochemical reference values for the endangered kiso horse.

Journal of equine science

Takasu M, Nagatani N, Tozaki T, Kakoi H, Maeda M, Murase T, Mukoyama H.
PMID: 24834006
J Equine Sci. 2013;24(4):75-8. doi: 10.1294/jes.24.75. Epub 2013 Dec 27.

To establish blood and biochemical references for the endangered Kiso horse, blood samples were collected from 111 adult Kiso horses, 74.5% of the existing breed. The samples were analyzed for 23 hematological and biochemical parameters to determine their means...

Effect of Repetitive Glucose Spike and Hypoglycaemia on Atherosclerosis and Death Rate in Apo E-Deficient Mice.

International journal of endocrinology

Nakajima K, Mita T, Osonoi Y, Azuma K, Takasu T, Fujitani Y, Watada H.
PMID: 26366172
Int J Endocrinol. 2015;2015:406394. doi: 10.1155/2015/406394. Epub 2015 Aug 20.

Epidemiological data suggest that postprandial hyperglycaemia and hypoglycaemia are potential risk factors for cardiovascular disease. However, the effects of repetitive postprandial glucose spikes, repetitive hypoglycaemia, and their combination on the progression of atherosclerosis remain largely unknown. The present study...

Clinical and histopathological features of myopathies in Japanese patients with anti-SRP autoantibodies.

Modern rheumatology

Takada T, Hirakata M, Suwa A, Kaneko Y, Kuwana M, Ishihara T, Ikeda Y.
PMID: 28925310
Mod Rheumatol. 2009 Apr;19(2):165. doi: 10.3109/s10165-009-0165-1.

No abstract available.

REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA).

Journal of phycology

Ito T, Asano Y, Tanaka Y, Takabe T.
PMID: 27021980
J Phycol. 2011 Jun;47(3):517-523. doi: 10.1111/j.1529-8817.2011.00977.x. Epub 2011 Apr 11.

It has been shown that marine algae produce the compatible solute dimethylsulfoniopropionate (DMSP) from methionine (Met) via four enzymatic reactions in which the third step, synthesis of 4-dimethylsulfonio-2-hydroxy-butyrate (DMSHB) from 4-methylthio-2-hydroxybutyrate (MTHB), is the committing step. However, regulation of...

A novel graft material for preventing cerebrospinal fluid leakage in skull base reconstruction: technical note of perifascial areolar tissue.

Journal of neurological surgery. Part B, Skull base

Hayashi N, Mitsuya K, Gorai K, Inoue K, Ito I, Nakagawa M, Nakasu Y.
PMID: 25685643
J Neurol Surg B Skull Base. 2015 Feb;76(1):7-11. doi: 10.1055/s-0034-1386655. Epub 2014 Aug 11.

Objectives Perifascial areolar tissue (PAT), a layer of loose connective tissue on the deep fascias with a rich vascular plexus, serves as a vital cover over defects with scarce vascularity. We report the usefulness of PAT as a nonvascularized...

Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer.

Molecular therapy. Methods & clinical development

Takada Y, Takada T, Lee MY, Swiderski DL, Kabara LL, Dolan DF, Raphael Y.
PMID: 26029729
Mol Ther Methods Clin Dev. 2015 May 27;2:15019. doi: 10.1038/mtm.2015.19. eCollection 2015.

The most common reason for sensorineural deafness is death of hair cells (HCs). Heat shock proteins (HSPs) are molecular chaperones that participate in folding, targeting, and degrading proteins. HSP expression is increased in response to various environmental stresses to...

A unique case of polymyositis with anti-signal recognition particle antibody complicated by subacute interstitial lung disease and subluxing arthropathy, resembling anti-synthetase syndrome.

Modern rheumatology

Hanaoka H, Kaneko Y, Suzuki S, Takada T, Hirakata M, Takeuchi T, Kuwana M.
PMID: 26707188
Mod Rheumatol. 2016 Nov;26(6):979-980. doi: 10.3109/14397595.2015.1129693. Epub 2016 Feb 16.

No abstract available.

Modifications of azoxymethane-induced carcinogenesis and 90-day oral toxicities of 2-tetradecylcyclobutanone as a radiolytic product of stearic acid in F344 rats.

Journal of toxicologic pathology

Sato M, Todoriki S, Takahashi T, Hafez E, Takasu C, Uehara H, Yamakage K, Kondo T, Matsumoto K, Furuta M, Izumi K.
PMID: 26028819
J Toxicol Pathol. 2015 Apr;28(2):99-107. doi: 10.1293/tox.2015-0002. Epub 2015 Feb 16.

A 90-day oral toxicity test in rats was performed to evaluate the toxicity of 2-tetradecylcyclobutanone (2-tDCB), a unique radiolytic product of stearic acid. Six-week-old male and female F344 rats (n=15/group) were given 2-tDCB at concentrations of 0, 12, 60...

Response-adapted treatment with upfront high-dose chemotherapy followed by autologous stem-cell transplantation rescue or consolidation phase high-dose methotrexate for primary central nervous system lymphoma: a long-term mono-center study.

SpringerPlus

Nakasu Y, Mitsuya K, Hayashi N, Okamura I, Mori K, Enami T, Tatara R, Nakasu S, Ikeda T.
PMID: 27066340
Springerplus. 2016 Mar 10;5:307. doi: 10.1186/s40064-016-1954-6. eCollection 2016.

Treatment regimens for primary central nervous system lymphoma (PCNSL) include high-dose methotrexate (HD-MTX)-based chemotherapy, with or without radiotherapy and are based on studies of selected patient groups. This retrospective study assessed a consistent strategy of response-adapted protocol applied for...

Extracorporeal abdominal massage may help prevent recurrent bile duct stones after endoscopic sphincterotomy.

Endoscopy international open

Uchida N, Hamaya S, Tatsuta M, Nakatsu T.
PMID: 27540575
Endosc Int Open. 2016 Aug;4(8):E870-3. doi: 10.1055/s-0042-109774. Epub 2016 Aug 09.

BACKGROUND AND STUDY AIMS: Endoscopic sphincterotomy (EST) is effective, but recurrent bile duct stones are a common late complication. Because there are still no effective therapies for preventing this complication, some patients have experienced bile duct stone recurrence many...

N-Heterocyclic Carbene Initiated Anionic Polymerization of (E,E)-Methyl Sorbate and Subsequent Ring-Closing to Cyclic Poly(alkyl sorbate).

Journal of the American Chemical Society

Hosoi Y, Takasu A, Matsuoka SI, Hayashi M.
PMID: 28990773
J Am Chem Soc. 2017 Oct 25;139(42):15005-15012. doi: 10.1021/jacs.7b06897. Epub 2017 Oct 16.

A diene-based cyclic polymer has been synthesized by the anionic polymerization of methyl sorbate (MS) by an N-heterocyclic carbene (NHC) in the presence of a bulky aluminum Lewis acid. We first polymerized methyl sorbate (MS) initiated by NHC in...

Showing 1 to 12 of 640 entries