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Showing 1 to 12 of 56 entries
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Robust SNP genotyping by multiplex PCR and arrayed primer extension.

BMC medical genomics

Podder M, Ruan J, Tripp BW, Chu ZE, Tebbutt SJ.
PMID: 18237385
BMC Med Genomics. 2008 Jan 31;1:5. doi: 10.1186/1755-8794-1-5.

BACKGROUND: Arrayed primer extension (APEX) is a microarray-based rapid minisequencing methodology that may have utility in 'personalized medicine' applications that involve genetic diagnostics of single nucleotide polymorphisms (SNPs). However, to date there have been few reports that objectively evaluate...

Evaluation of .

Frontiers in oncology

Lee ST, Tebbutt N, Gan HK, Liu Z, Sachinidis J, Pathmaraj K, Scott AM.
PMID: 33816239
Front Oncol. 2021 Mar 17;11:606210. doi: 10.3389/fonc.2021.606210. eCollection 2021.

INTRODUCTION: Tumor hypoxia and angiogenesis are implicated in tumor growth and metastases, and anti-angiogenic therapies have an important role in treating patients with metastatic colorectal cancer. However, the prevalence of hypoxia has not been fully evaluated in colorectal liver...

Balancing the Risks and Benefits of COVID-19 Vaccination for Pregnant Women and Their Children.

Frontiers in immunology

Yang C, Zhao H, Tebbutt SJ.
PMID: 34975839
Front Immunol. 2021 Dec 16;12:748456. doi: 10.3389/fimmu.2021.748456. eCollection 2021.

No abstract available.

Impact of geography on prognostic outcomes of 21,509 patients with metastatic colorectal cancer enrolled in clinical trials: an ARCAD database analysis.

Therapeutic advances in medical oncology

Yin J, Dawood S, Cohen R, Meyers J, Zalcberg J, Yoshino T, Seymour M, Maughan T, Saltz L, Van Cutsem E, Venook A, Schmoll HJ, Goldberg R, Hoff P, Hecht JR, Hurwitz H, Punt C, Diaz Rubio E, Koopman M, Cremolini C, Heinemann V, Tournigard C, Bokemeyer C, Fuchs C, Tebbutt N, Souglakos J, Doulliard JY, Kabbinavar F, Chibaudel B, de Gramont A, Shi Q, Grothey A, Adams R.
PMID: 34262614
Ther Adv Med Oncol. 2021 Jun 30;13:17588359211020547. doi: 10.1177/17588359211020547. eCollection 2021.

BACKGROUND: Benchmarking international cancer survival differences is necessary to evaluate and improve healthcare systems. Our aim was to assess the potential regional differences in outcomes among patients with metastatic colorectal cancer (mCRC) participating in international randomized clinical trials (RCTs).DESIGN:...

Stabilisation.

British dental journal

Tebbutt JE, Bhanji AH, Graham RM, Nasry H.
PMID: 34050276
Br Dent J. 2021 May;230(10):626. doi: 10.1038/s41415-021-3102-0.

No abstract available.

Ontogeny of plasma cytokine and chemokine concentrations across the first week of human life.

Cytokine

Smolen KK, Plotkin AL, Shannon CP, Idoko OT, Pak J, Darboe A, van Haren S, Amenyogbe N, Tebbutt SJ, Kollmann TR, Kampmann B, Ozonoff A, Levy O, Odumade OA.
PMID: 34597920
Cytokine. 2021 Dec;148:155704. doi: 10.1016/j.cyto.2021.155704. Epub 2021 Sep 28.

INTRODUCTION/BACKGROUND & AIMS: Early life is marked by distinct and rapidly evolving immunity and increased susceptibility to infection. The vulnerability of the newborn reflects development of a complex immune system in the face of rapidly changing demands during the...

Epigenetic blood biomarkers of aging and mortality in COPD.

The European respiratory journal

Hernandez Cordero AI, Yang CX, Milne S, Li X, Hollander Z, Chen V, Ng R, Tebbutt SJ, Leung JM, Sin DD.
PMID: 34561282
Eur Respir J. 2021 Sep 24; doi: 10.1183/13993003.01890-2021. Epub 2021 Sep 24.

No abstract available.

Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea.

Frontiers in pediatrics

Idoko OT, Smolen KK, Wariri O, Imam A, Shannon CP, Dibassey T, Diray-Arce J, Darboe A, Strandmark J, Ben-Othman R, Odumade OA, McEnaney K, Amenyogbe N, Pomat WS, van Haren S, Sanchez-Schmitz G, Brinkman RR, Steen H, Hancock REW, Tebbutt SJ, Richmond PC, van den Biggelaar AHJ, Kollmann TR, Levy O, Ozonoff A, Kampmann B.
PMID: 32426309
Front Pediatr. 2020 Apr 30;8:197. doi: 10.3389/fped.2020.00197. eCollection 2020.

No abstract available.

Balancing the Risks and Benefits of COVID-19 Vaccination for Pregnant Women and Their Children.

Frontiers in immunology

Yang C, Zhao H, Tebbutt SJ.
PMID: 34975839
Front Immunol. 2021 Dec 16;12:748456. doi: 10.3389/fimmu.2021.748456. eCollection 2021.

No abstract available.

Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses.

ERJ open research

Rajasekaran A, He D, Yue A, Singh A, Shannon CP, FitzGerald JM, Boulet LP, O'Byrne PM, Gauvreau GM, Tebbutt SJ.
PMID: 31720291
ERJ Open Res. 2019 Nov 04;5(4). doi: 10.1183/23120541.00107-2019. eCollection 2019 Oct.

No abstract available.

Effects of low-intensity and high-intensity cycling with diesel exhaust exposure on soluble P-selectin, E-selectin, I-CAM-1, VCAM-1 and complete blood count.

BMJ open sport & exercise medicine

Giles LV, Tebbutt SJ, Carlsten C, Koehle MS.
PMID: 31803496
BMJ Open Sport Exerc Med. 2019 Nov 24;5(1):e000625. doi: 10.1136/bmjsem-2019-000625. eCollection 2019.

BACKGROUND: Exposure to particulate matter 2.5 μm or less (PMAIM: To determine how DE exposure during exercise of varying intensities affects adhesion molecules and markers of systemic inflammation.METHODS: Eighteen males performed 30 min cycling bouts at low intensity and...

Longitudinal analysis of whole blood transcriptomes to explore molecular signatures associated with acute renal allograft rejection.

Bioinformatics and biology insights

Shin H, Günther O, Hollander Z, Wilson-McManus JE, Ng RT, Balshaw R, Keown PA, McMaster R, McManus BM, Isbel NM, Knoll G, Tebbutt SJ.
PMID: 24526836
Bioinform Biol Insights. 2014 Jan 22;8:17-33. doi: 10.4137/BBI.S13376.. eCollection 2014.

In this study, we explored a time course of peripheral whole blood transcriptomes from kidney transplantation patients who either experienced an acute rejection episode or did not in order to better delineate the immunological and biological processes measureable in...

Showing 1 to 12 of 56 entries