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Identification of a variant associated with adult-type hypolactasia

adult

Enattah NS, Terwilliger JD.
GSID: D2y2X2WcoxAJ
NS Enattah, T Sahi, E Savilahti, JD Terwilliger… - Nature …, 2002 - nature.com

Adult-type hypolactasia, also known as lactase non-persistence (lactose intolerance), is a common autosomal recessive condition resulting from the physiological decline in activity of …

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Enattah, N. S., Sahi, T., Savilahti, E., Terwilliger, J. D., Peltonen, L., & Järvelä, I. (2002). Identification of a variant associated with adult-type hypolactasia. Nature genetics, 30(2), 233-237.
Enattah, Nabil Sabri, et al. "Identification of a variant associated with adult-type hypolactasia." Nature genetics 30.2 (2002): 233-237.
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Bayesian difference refinement.

Acta crystallographica. Section D, Biological crystallography

Terwilliger TC, Berendzen J.
PMID: 15299610
Acta Crystallogr D Biol Crystallogr. 1996 Sep 01;52:1004-11. doi: 10.1107/S0907444996006725.

Interest in a pair of highly isomorphous structures often focuses on the differences between them. In cases where substantial correlated model errors exist or where there are differences in the quality of the two experimental data sets (cases quite...

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Terwilliger TC, Berendzen J. Bayesian difference refinement. Acta Crystallogr D Biol Crystallogr. 1996;52:1004-11doi: 10.1107/S0907444996006725.
Terwilliger, T. C., & Berendzen, J. (1996). Bayesian difference refinement. Acta crystallographica. Section D, Biological crystallography, 521004-11. https://doi.org/10.1107/S0907444996006725
Terwilliger, T C, and Berendzen, J. "Bayesian difference refinement." Acta crystallographica. Section D, Biological crystallography vol. 52 (1996): 1004-11. doi: https://doi.org/10.1107/S0907444996006725
Terwilliger TC, Berendzen J. Bayesian difference refinement. Acta Crystallogr D Biol Crystallogr. 1996 Sep 01;52:1004-11. doi: 10.1107/S0907444996006725. PMID: 15299610.
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Difference refinement: obtaining differences between two related structures.

Acta crystallographica. Section D, Biological crystallography

Terwilliger TC, Berendzen J.
PMID: 15299790
Acta Crystallogr D Biol Crystallogr. 1995 Sep 01;51:609-18. doi: 10.1107/S0907444994013247.

There are many examples in macromolecular crystallography where interest focuses on the differences between a previously determined 'native' structure and a nearly isomorphous 'variant'. In such cases, a useful approach to atomic refinement of the variant structure is through...

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Terwilliger TC, Berendzen J. Difference refinement: obtaining differences between two related structures. Acta Crystallogr D Biol Crystallogr. 1995;51:609-18doi: 10.1107/S0907444994013247.
Terwilliger, T. C., & Berendzen, J. (1995). Difference refinement: obtaining differences between two related structures. Acta crystallographica. Section D, Biological crystallography, 51609-18. https://doi.org/10.1107/S0907444994013247
Terwilliger, T C, and Berendzen, J. "Difference refinement: obtaining differences between two related structures." Acta crystallographica. Section D, Biological crystallography vol. 51 (1995): 609-18. doi: https://doi.org/10.1107/S0907444994013247
Terwilliger TC, Berendzen J. Difference refinement: obtaining differences between two related structures. Acta Crystallogr D Biol Crystallogr. 1995 Sep 01;51:609-18. doi: 10.1107/S0907444994013247. PMID: 15299790.
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MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI.

Proceedings of the National Academy of Sciences of the United States of America

Fenn WO, Gerschman R, Gilbert DL, Terwilliger DE, Cothran FV.
PMID: 16590131
Proc Natl Acad Sci U S A. 1957 Dec 15;43(12):1027-32. doi: 10.1073/pnas.43.12.1027.

No abstract available.

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Fenn WO, Gerschman R, Gilbert DL, et al. MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1957;43(12):1027-32doi: 10.1073/pnas.43.12.1027.
Fenn, W. O., Gerschman, R., Gilbert, D. L., Terwilliger, D. E., & Cothran, F. V. (1957). MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI. Proceedings of the National Academy of Sciences of the United States of America, 43(12), 1027-32. https://doi.org/10.1073/pnas.43.12.1027
Fenn, W O, et al. "MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI." Proceedings of the National Academy of Sciences of the United States of America vol. 43,12 (1957): 1027-32. doi: https://doi.org/10.1073/pnas.43.12.1027
Fenn WO, Gerschman R, Gilbert DL, Terwilliger DE, Cothran FV. MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1957 Dec 15;43(12):1027-32. doi: 10.1073/pnas.43.12.1027. PMID: 16590131; PMCID: PMC528581.
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Graphical tools for macromolecular crystallography in PHENIX.

Journal of applied crystallography

Echols N, Grosse-Kunstleve RW, Afonine PV, Bunkóczi G, Chen VB, Headd JJ, McCoy AJ, Moriarty NW, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Adams PD.
PMID: 22675231
J Appl Crystallogr. 2012 Jun 01;45:581-586. doi: 10.1107/S0021889812017293. Epub 2012 May 16.

A new Python-based graphical user interface for the PHENIX suite of crystallography software is described. This interface unifies the command-line programs and their graphical displays, simplifying the development of new interfaces and avoiding duplication of function. With careful design,...

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Echols N, Grosse-Kunstleve RW, Afonine PV, et al. Graphical tools for macromolecular crystallography in PHENIX. J Appl Crystallogr. 2012;45:581-586doi: 10.1107/S0021889812017293.
Echols, N., Grosse-Kunstleve, R. W., Afonine, P. V., Bunkóczi, G., Chen, V. B., Headd, J. J., McCoy, A. J., Moriarty, N. W., Read, R. J., Richardson, D. C., Richardson, J. S., Terwilliger, T. C., & Adams, P. D. (2012). Graphical tools for macromolecular crystallography in PHENIX. Journal of applied crystallography, 45581-586. https://doi.org/10.1107/S0021889812017293
Echols, Nathaniel, et al. "Graphical tools for macromolecular crystallography in PHENIX." Journal of applied crystallography vol. 45 (2012): 581-586. doi: https://doi.org/10.1107/S0021889812017293
Echols N, Grosse-Kunstleve RW, Afonine PV, Bunkóczi G, Chen VB, Headd JJ, McCoy AJ, Moriarty NW, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Adams PD. Graphical tools for macromolecular crystallography in PHENIX. J Appl Crystallogr. 2012 Jun 01;45:581-586. doi: 10.1107/S0021889812017293. Epub 2012 May 16. PMID: 22675231; PMCID: PMC3359726.
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Archiving raw crystallographic data.

Acta crystallographica. Section D, Biological crystallography

Terwilliger TC.
PMID: 25286835
Acta Crystallogr D Biol Crystallogr. 2014 Oct;70:2500-1. doi: 10.1107/S139900471402118X. Epub 2014 Sep 30.

This article describes some of the activities of the IUCr Diffraction Data Deposition Working Group and introduces a collection of articles discussing the archiving of diffraction images.

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Terwilliger TC. Archiving raw crystallographic data. Acta Crystallogr D Biol Crystallogr. 2014;70:2500-1doi: 10.1107/S139900471402118X.
Terwilliger, T. C. (2014). Archiving raw crystallographic data. Acta crystallographica. Section D, Biological crystallography, 702500-1. https://doi.org/10.1107/S139900471402118X
Terwilliger, Thomas C. "Archiving raw crystallographic data." Acta crystallographica. Section D, Biological crystallography vol. 70 (2014): 2500-1. doi: https://doi.org/10.1107/S139900471402118X
Terwilliger TC. Archiving raw crystallographic data. Acta Crystallogr D Biol Crystallogr. 2014 Oct;70:2500-1. doi: 10.1107/S139900471402118X. Epub 2014 Sep 30. PMID: 25286835; PMCID: PMC8494196.
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Gender Differences in Withdrawing Infants.

Global pediatric health

Stevens S, Flaugher T, Hughes K, Terwilliger C, Copley J, Mohan S.
PMID: 29796407
Glob Pediatr Health. 2018 May 18;5:2333794X18775886. doi: 10.1177/2333794X18775886. eCollection 2018.

No abstract available.

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Stevens S, Flaugher T, Hughes K, et al. Gender Differences in Withdrawing Infants. Glob Pediatr Health. 2018;5:2333794X18775886doi: 10.1177/2333794X18775886.
Stevens, S., Flaugher, T., Hughes, K., Terwilliger, C., Copley, J., & Mohan, S. (2018). Gender Differences in Withdrawing Infants. Global pediatric health, 52333794X18775886. https://doi.org/10.1177/2333794X18775886
Stevens, Sarah, et al. "Gender Differences in Withdrawing Infants." Global pediatric health vol. 5 (2018): 2333794X18775886. doi: https://doi.org/10.1177/2333794X18775886
Stevens S, Flaugher T, Hughes K, Terwilliger C, Copley J, Mohan S. Gender Differences in Withdrawing Infants. Glob Pediatr Health. 2018 May 18;5:2333794X18775886. doi: 10.1177/2333794X18775886. eCollection 2018. PMID: 29796407; PMCID: PMC5960852.
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Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients.

PHAGE (New Rochelle, N.Y.)

Terwilliger AL, Gu Liu C, Green SI, Clark JR, Salazar KC, Hernandez Santos H, Heckmann ER, Trautner BW, Ramig RF, Maresso AW.
PMID: 32626851
Phage (New Rochelle). 2020 Jun 01;1(2):66-74. doi: 10.1089/phage.2020.0007. Epub 2020 Jun 16.

Mutation is the most powerful driver of change for life on Earth. Pathogenic bacteria utilize mutation as a means to survive strong live-die selective pressures generated by chemical antibiotics. As such, the traditional drug-making pipeline, characterized by significant financial...

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Terwilliger AL, Gu Liu C, Green SI, et al. Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients. Phage (New Rochelle). 2020;1(2):66-74doi: 10.1089/phage.2020.0007.
Terwilliger, A. L., Gu Liu, C., Green, S. I., Clark, J. R., Salazar, K. C., Hernandez Santos, H., Heckmann, E. R., Trautner, B. W., Ramig, R. F., & Maresso, A. W. (2020). Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients. PHAGE (New Rochelle, N.Y.), 1(2), 66-74. https://doi.org/10.1089/phage.2020.0007
Terwilliger, Austen L, et al. "Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients." PHAGE (New Rochelle, N.Y.) vol. 1,2 (2020): 66-74. doi: https://doi.org/10.1089/phage.2020.0007
Terwilliger AL, Gu Liu C, Green SI, Clark JR, Salazar KC, Hernandez Santos H, Heckmann ER, Trautner BW, Ramig RF, Maresso AW. Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients. Phage (New Rochelle). 2020 Jun 01;1(2):66-74. doi: 10.1089/phage.2020.0007. Epub 2020 Jun 16. PMID: 32626851; PMCID: PMC7327541.
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Phage Therapy Related Microbial Succession Associated with Successful Clinical Outcome for a Recurrent Urinary Tract Infection.

Viruses

Terwilliger A, Clark J, Karris M, Hernandez-Santos H, Green S, Aslam S, Maresso A.
PMID: 34696479
Viruses. 2021 Oct 12;13(10). doi: 10.3390/v13102049.

We rationally designed a bacteriophage cocktail to treat a 56-year-old male liver transplant patient with complex, recurrent prostate and urinary tract infections caused by an extended-spectrum beta-lactamase (ESBL)-producing

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Terwilliger A, Clark J, Karris M, et al. Phage Therapy Related Microbial Succession Associated with Successful Clinical Outcome for a Recurrent Urinary Tract Infection. Viruses. 2021;13(10)doi: 10.3390/v13102049.
Terwilliger, A., Clark, J., Karris, M., Hernandez-Santos, H., Green, S., Aslam, S., & Maresso, A. (2021). Phage Therapy Related Microbial Succession Associated with Successful Clinical Outcome for a Recurrent Urinary Tract Infection. Viruses, 13(10), . https://doi.org/10.3390/v13102049
Terwilliger, Austen, et al. "Phage Therapy Related Microbial Succession Associated with Successful Clinical Outcome for a Recurrent Urinary Tract Infection." Viruses vol. 13,10 (2021). doi: https://doi.org/10.3390/v13102049
Terwilliger A, Clark J, Karris M, Hernandez-Santos H, Green S, Aslam S, Maresso A. Phage Therapy Related Microbial Succession Associated with Successful Clinical Outcome for a Recurrent Urinary Tract Infection. Viruses. 2021 Oct 12;13(10). doi: 10.3390/v13102049. PMID: 34696479; PMCID: PMC8541385.
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A synthetic antibiotic class overcoming bacterial multidrug resistance.

Nature

Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG.
PMID: 34707295
Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27.

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern

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Mitcheltree MJ, Pisipati A, Syroegin EA, et al. A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature. 2021;599(7885):507-512doi: 10.1038/s41586-021-04045-6.
Mitcheltree, M. J., Pisipati, A., Syroegin, E. A., Silvestre, K. J., Klepacki, D., Mason, J. D., Terwilliger, D. W., Testolin, G., Pote, A. R., Wu, K. J. Y., Ladley, R. P., Chatman, K., Mankin, A. S., Polikanov, Y. S., & Myers, A. G. (2021). A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature, 599(7885), 507-512. https://doi.org/10.1038/s41586-021-04045-6
Mitcheltree, Matthew J, et al. "A synthetic antibiotic class overcoming bacterial multidrug resistance." Nature vol. 599,7885 (2021): 507-512. doi: https://doi.org/10.1038/s41586-021-04045-6
Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG. A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27. PMID: 34707295; PMCID: PMC8549432.
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Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study.

Hypertension research : official journal of the Japanese Society of Hypertension

Melgarejo JD, Maestre GE, Mena LJ, Lee JH, Petitto M, Chávez CA, Calmon G, Silva E, Thijs L, Al-Aswad LA, Terwilliger JD, De Moraes CG, Wei FF, Vanassche T, Verhamme P, Staessen JA, Zhang ZY.
PMID: 34253881
Hypertens Res. 2021 Sep;44(9):1105-1112. doi: 10.1038/s41440-021-00687-1. Epub 2021 Jul 12.

Hypoperfusion of the optic nerve might be involved in the pathogenesis of normal-tension glaucomatous optic neuropathy (GON). Mean arterial pressure (MAP) drives ocular perfusion, but no previous studies have addressed the risk of GON in relation to blood pressure...

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Melgarejo JD, Maestre GE, Mena LJ, et al. Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study. Hypertens Res. 2021;44(9):1105-1112doi: 10.1038/s41440-021-00687-1.
Melgarejo, J. D., Maestre, G. E., Mena, L. J., Lee, J. H., Petitto, M., Chávez, C. A., Calmon, G., Silva, E., Thijs, L., Al-Aswad, L. A., Terwilliger, J. D., De Moraes, C. G., Wei, F. F., Vanassche, T., Verhamme, P., Staessen, J. A., & Zhang, Z. Y. (2021). Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study. Hypertension research : official journal of the Japanese Society of Hypertension, 44(9), 1105-1112. https://doi.org/10.1038/s41440-021-00687-1
Melgarejo, Jesus D, et al. "Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study." Hypertension research : official journal of the Japanese Society of Hypertension vol. 44,9 (2021): 1105-1112. doi: https://doi.org/10.1038/s41440-021-00687-1
Melgarejo JD, Maestre GE, Mena LJ, Lee JH, Petitto M, Chávez CA, Calmon G, Silva E, Thijs L, Al-Aswad LA, Terwilliger JD, De Moraes CG, Wei FF, Vanassche T, Verhamme P, Staessen JA, Zhang ZY. Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study. Hypertens Res. 2021 Sep;44(9):1105-1112. doi: 10.1038/s41440-021-00687-1. Epub 2021 Jul 12. PMID: 34253881; PMCID: PMC8429242.
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Carbon isotopic ratios of atmospheric CO(2) affect the delta(13)C values of heterotrophic growth in Nicotiana tabacum.

Plant science : an international journal of experimental plant biology

Le Roux-Swarthout D, Terwilliger, Christianson M, Martin C, Madhavan S.
PMID: 11166444
Plant Sci. 2001 Feb 05;160(3):563-570. doi: 10.1016/s0168-9452(00)00427-1.

Heterotrophic Nicotiana tabacum (L. CV. Wisconsin 38) plants are enriched in 13C relative to the carbon sources in their growth medium. We examined whether carboxylation via phosphoenolpyruvate carboxylase contributes to the enrichment. Achlorophyllous plants were produced using an inhibitor...

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Le Roux-Swarthout D, Terwilliger, Christianson M, et al. Carbon isotopic ratios of atmospheric CO(2) affect the delta(13)C values of heterotrophic growth in Nicotiana tabacum. Plant Sci. 2001;160(3):563-570doi: 10.1016/s0168-9452(00)00427-1.
Le Roux-Swarthout, D., Terwilliger, Christianson, M., Martin, C., & Madhavan, S. (2001). Carbon isotopic ratios of atmospheric CO(2) affect the delta(13)C values of heterotrophic growth in Nicotiana tabacum. Plant science : an international journal of experimental plant biology, 160(3), 563-570. https://doi.org/10.1016/s0168-9452(00)00427-1
Le Roux-Swarthout, D, et al. "Carbon isotopic ratios of atmospheric CO(2) affect the delta(13)C values of heterotrophic growth in Nicotiana tabacum." Plant science : an international journal of experimental plant biology vol. 160,3 (2001): 563-570. doi: https://doi.org/10.1016/s0168-9452(00)00427-1
Le Roux-Swarthout D, Terwilliger, Christianson M, Martin C, Madhavan S. Carbon isotopic ratios of atmospheric CO(2) affect the delta(13)C values of heterotrophic growth in Nicotiana tabacum. Plant Sci. 2001 Feb 05;160(3):563-570. doi: 10.1016/s0168-9452(00)00427-1. PMID: 11166444.
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Showing 1 to 12 of 72 entries