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Showing 1 to 12 of 13 entries
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Case report: Tension pneumomediastinum from opioid inhalation.

The American journal of emergency medicine

Nene RV, Hryniewicki AT, Roderick E, Chicotka S, Vazquez MH, Thistlewaite PA, Coffey C, Odish MF.
PMID: 34556391
Am J Emerg Med. 2021 Sep 04; doi: 10.1016/j.ajem.2021.09.008. Epub 2021 Sep 04.

Pneumomediastinum is a rare complication of substance use, likely due to a Valsalva maneuver after drug inhalation. There are no previously documented associations between pneumomediastinum and opioid use. A 30-year-old man with a history of recent heroin and fentanyl...

TRPC6, a therapeutic target for pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX.
PMID: 34704831
Am J Physiol Lung Cell Mol Physiol. 2021 Dec 01;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27.

Idiopathic pulmonary arterial hypertension (PAH) is a fatal and progressive disease. Sustained vasoconstriction due to pulmonary arterial smooth muscle cell (PASMC) contraction and concentric arterial remodeling due partially to PASMC proliferation are the major causes for increased pulmonary vascular...

Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung.

Pulmonary circulation

Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX.
PMID: 33282184
Pulm Circ. 2020 Nov 25;10(4):2045894020956592. doi: 10.1177/2045894020956592. eCollection 2020.

Hypoxic Pulmonary Vasoconstriction (HPV) is an important physiological mechanism of the lungs that matches perfusion to ventilation thus maximizing O

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19.

bioRxiv : the preprint server for biology

Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S.
PMID: 33106807
bioRxiv. 2021 May 05; doi: 10.1101/2020.10.17.344002.

SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model that...

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19.

bioRxiv : the preprint server for biology

Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S.
PMID: 33106807
bioRxiv. 2021 May 05; doi: 10.1101/2020.10.17.344002.

SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model that...

Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.

American journal of physiology. Cell physiology

Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX.
PMID: 34669509
Am J Physiol Cell Physiol. 2021 Dec 01;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20.

Piezo is a mechanosensitive cation channel responsible for stretch-mediated Ca

Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.

American journal of physiology. Cell physiology

Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX.
PMID: 34669509
Am J Physiol Cell Physiol. 2021 Dec 01;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20.

Piezo is a mechanosensitive cation channel responsible for stretch-mediated Ca

TRPC6, a therapeutic target for pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX.
PMID: 34704831
Am J Physiol Lung Cell Mol Physiol. 2021 Dec 01;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27.

Idiopathic pulmonary arterial hypertension (PAH) is a fatal and progressive disease. Sustained vasoconstriction due to pulmonary arterial smooth muscle cell (PASMC) contraction and concentric arterial remodeling due partially to PASMC proliferation are the major causes for increased pulmonary vascular...

Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.

Frontiers in physiology

Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX.
PMID: 34408668
Front Physiol. 2021 Aug 02;12:714785. doi: 10.3389/fphys.2021.714785. eCollection 2021.

Excessive pulmonary artery (PA) smooth muscle cell (PASMC) proliferation and migration are implicated in the development of pathogenic pulmonary vascular remodeling characterized by concentric arterial wall thickening and arteriole muscularization in patients with pulmonary arterial hypertension (PAH). Pulmonary artery...

Crisis in recruitment.

The British journal of general practice : the journal of the Royal College of General Practitioners

Thistlewaite JE, Butler S, Singleton C.
PMID: 8703533
Br J Gen Pract. 1996 Apr;46(405):254-5.
Free PMC Article

No abstract available.

Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization.

Pulmonary circulation

Xiong M, Jain PP, Chen J, Babicheva A, Zhao T, Alotaibi M, Kim NH, Lai N, Izadi A, Rodriguez M, Li J, Balistrieri A, Balistrieri F, Parmisano S, Sun X, Voldez-Jasso D, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX.
PMID: 34531976
Pulm Circ. 2021 Sep 08;11(4):20458940211041512. doi: 10.1177/20458940211041512. eCollection 2021.

Pulmonary arterial hypertension is a progressive and fatal disease and rodents with experimental pulmonary hypertension (PH) are often used to study pathogenic mechanisms, identify therapeutic targets, and develop novel drugs for treatment. Here we describe a hands-on set of...

Case report: Tension pneumomediastinum from opioid inhalation.

The American journal of emergency medicine

Nene RV, Hryniewicki AT, Roderick E, Chicotka S, Vazquez MH, Thistlewaite PA, Coffey C, Odish MF.
PMID: 34556391
Am J Emerg Med. 2021 Sep 04; doi: 10.1016/j.ajem.2021.09.008. Epub 2021 Sep 04.

Pneumomediastinum is a rare complication of substance use, likely due to a Valsalva maneuver after drug inhalation. There are no previously documented associations between pneumomediastinum and opioid use. A 30-year-old man with a history of recent heroin and fentanyl...

Showing 1 to 12 of 13 entries