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SU-E-T-100: How to Improve the Dose Accuracy for Gantry Angle Dependent Patient Specific IMRT QA Using 2D Ion Chamber Array with Octavius Phantom.

Medical physics

Choi D, Nookala P, Patyal B.
PMID: 28517133
Med Phys. 2012 Jun;39(6):3725. doi: 10.1118/1.4735158.

PURPOSE: To determine the cross calibration factors which can predict more accurate dose distribution for fixed beam IMRT QA using Octavius phantom.METHODS: The ion chamber based Octavius 2D-array detector (PTW, Freiburg, Germany) is a step in the right direction...

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Choi D, Nookala P, Patyal B. SU-E-T-100: How to Improve the Dose Accuracy for Gantry Angle Dependent Patient Specific IMRT QA Using 2D Ion Chamber Array with Octavius Phantom. Med Phys. 2012;39(6):3725doi: 10.1118/1.4735158.
Choi, D., Nookala, P., & Patyal, B. (2012). SU-E-T-100: How to Improve the Dose Accuracy for Gantry Angle Dependent Patient Specific IMRT QA Using 2D Ion Chamber Array with Octavius Phantom. Medical physics, 39(6), 3725. https://doi.org/10.1118/1.4735158
Choi, D, et al. "SU-E-T-100: How to Improve the Dose Accuracy for Gantry Angle Dependent Patient Specific IMRT QA Using 2D Ion Chamber Array with Octavius Phantom." Medical physics vol. 39,6 (2012): 3725. doi: https://doi.org/10.1118/1.4735158
Choi D, Nookala P, Patyal B. SU-E-T-100: How to Improve the Dose Accuracy for Gantry Angle Dependent Patient Specific IMRT QA Using 2D Ion Chamber Array with Octavius Phantom. Med Phys. 2012 Jun;39(6):3725. doi: 10.1118/1.4735158. PMID: 28517133.
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An unusual cause of altered mental status in elderly-acute cerebellitis: a case report and review.

Case reports in medicine

Patel P, Rayamajhi S, Tokala H, Laird-Fick H.
PMID: 24382966
Case Rep Med. 2013;2013:653925. doi: 10.1155/2013/653925. Epub 2013 Dec 09.

Acute cerebellitis is a rare diagnosis found mostly in the pediatric population. The etiology, in most instances, is unknown. We describe the case of a 61-year-old woman who presented with acute mental status changes, signs of cerebellar dysfunction, and...

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Patel P, Rayamajhi S, Tokala H, et al. An unusual cause of altered mental status in elderly-acute cerebellitis: a case report and review. Case Rep Med. 2013;2013:653925doi: 10.1155/2013/653925.
Patel, P., Rayamajhi, S., Tokala, H., & Laird-Fick, H. (2013). An unusual cause of altered mental status in elderly-acute cerebellitis: a case report and review. Case reports in medicine, 2013653925. https://doi.org/10.1155/2013/653925
Patel, Priyank, et al. "An unusual cause of altered mental status in elderly-acute cerebellitis: a case report and review." Case reports in medicine vol. 2013 (2013): 653925. doi: https://doi.org/10.1155/2013/653925
Patel P, Rayamajhi S, Tokala H, Laird-Fick H. An unusual cause of altered mental status in elderly-acute cerebellitis: a case report and review. Case Rep Med. 2013;2013:653925. doi: 10.1155/2013/653925. Epub 2013 Dec 09. PMID: 24382966; PMCID: PMC3872022.
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Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus.

Frontiers in cellular neuroscience

Takkala P, Woodin MA.
PMID: 23450426
Front Cell Neurosci. 2013 Feb 28;7:16. doi: 10.3389/fncel.2013.00016. eCollection 2013.

Disinhibition-mediated long-term potentiation (LTP) in the CA1 region of the hippocampus involves GABAergic synaptic plasticity at feedforward inhibitory inputs, resulting in the reduced shunting of glutamatergic excitatory currents. The GABAergic plasticity which underlies disinhibition-mediated LTP results from a Ca(2+)-dependent...

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Takkala P, Woodin MA. Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Front Cell Neurosci. 2013;7:16doi: 10.3389/fncel.2013.00016.
Takkala, P., & Woodin, M. A. (2013). Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Frontiers in cellular neuroscience, 716. https://doi.org/10.3389/fncel.2013.00016
Takkala, Petri, and Woodin, Melanie A. "Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus." Frontiers in cellular neuroscience vol. 7 (2013): 16. doi: https://doi.org/10.3389/fncel.2013.00016
Takkala P, Woodin MA. Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Front Cell Neurosci. 2013 Feb 28;7:16. doi: 10.3389/fncel.2013.00016. eCollection 2013. PMID: 23450426; PMCID: PMC3584297.
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Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs.

BMJ open

Thokala P, Baalbaki H, Brennan A, Pandor A, Stevens JW, Gomersall T, Wang J, Bakhai A, Al-Mohammad A, Cleland J, Cowie MR, Wong R.
PMID: 24048626
BMJ Open. 2013 Sep 18;3(9):e003250. doi: 10.1136/bmjopen-2013-003250.

OBJECTIVES: To estimate the cost-effectiveness of remote monitoring strategies versus usual care for adults recently discharged after a heart failure (HF) exacerbation.DESIGN: Decision analysis modelling of cost-effectiveness using secondary data sources.SETTING: Acute hospitals in the UK.PATIENTS: Patients recently discharged...

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Thokala P, Baalbaki H, Brennan A, et al. Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs. BMJ Open. 2013;3(9):e003250doi: 10.1136/bmjopen-2013-003250.
Thokala, P., Baalbaki, H., Brennan, A., Pandor, A., Stevens, J. W., Gomersall, T., Wang, J., Bakhai, A., Al-Mohammad, A., Cleland, J., Cowie, M. R., & Wong, R. (2013). Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs. BMJ open, 3(9), e003250. https://doi.org/10.1136/bmjopen-2013-003250
Thokala, Praveen, et al. "Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs." BMJ open vol. 3,9 (2013): e003250. doi: https://doi.org/10.1136/bmjopen-2013-003250
Thokala P, Baalbaki H, Brennan A, Pandor A, Stevens JW, Gomersall T, Wang J, Bakhai A, Al-Mohammad A, Cleland J, Cowie MR, Wong R. Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs. BMJ Open. 2013 Sep 18;3(9):e003250. doi: 10.1136/bmjopen-2013-003250. PMID: 24048626; PMCID: PMC3780300.
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β-Carboline directed regioselective hydroxylation by employing Cu(OAc).

Organic & biomolecular chemistry

Bora D, Tokala R, John SE, Prasanth B, Shankaraiah N.
PMID: 32159570
Org Biomol Chem. 2020 Mar 25;18(12):2307-2311. doi: 10.1039/d0ob00250j.

A β-carboline directed regioselective C-H activation protocol for hydroxylation has been developed by employing Cu(OAc)2, a cost-effective 3d metal. This fastidious reaction proceeds under microwave irradiation and furnishes exclusively ortho-hydroxylated products with moderate to good yields under greener reaction...

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Bora D, Tokala R, John SE, et al. β-Carboline directed regioselective hydroxylation by employing Cu(OAc). Org Biomol Chem. 2020;18(12):2307-2311doi: 10.1039/d0ob00250j.
Bora, D., Tokala, R., John, S. E., Prasanth, B., & Shankaraiah, N. (2020). β-Carboline directed regioselective hydroxylation by employing Cu(OAc). Organic & biomolecular chemistry, 18(12), 2307-2311. https://doi.org/10.1039/d0ob00250j
Bora, Darshana, et al. "β-Carboline directed regioselective hydroxylation by employing Cu(OAc)." Organic & biomolecular chemistry vol. 18,12 (2020): 2307-2311. doi: https://doi.org/10.1039/d0ob00250j
Bora D, Tokala R, John SE, Prasanth B, Shankaraiah N. β-Carboline directed regioselective hydroxylation by employing Cu(OAc). Org Biomol Chem. 2020 Mar 25;18(12):2307-2311. doi: 10.1039/d0ob00250j. PMID: 32159570.
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Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics.

BJGP open

Sadler S, Holmes M, Ren S, Holden S, Jha S, Thokala P.
PMID: 30564681
BJGP Open. 2017 Oct 04;1(3):bjgpopen17X101097. doi: 10.3399/bjgpopen17X101097.

BACKGROUND: Urinary tract infections (UTIs) are one of the most common reasons for women to attend primary care. There are four different antibiotics currently recommended in England for treatment of uncomplicated UTI but little evidence on their comparative cost-effectiveness.AIM:...

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Sadler S, Holmes M, Ren S, et al. Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics. BJGP Open. 2017;1(3):bjgpopen17X101097doi: 10.3399/bjgpopen17X101097.
Sadler, S., Holmes, M., Ren, S., Holden, S., Jha, S., & Thokala, P. (2017). Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics. BJGP open, 1(3), bjgpopen17X101097. https://doi.org/10.3399/bjgpopen17X101097
Sadler, Susannah, et al. "Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics." BJGP open vol. 1,3 (2017): bjgpopen17X101097. doi: https://doi.org/10.3399/bjgpopen17X101097
Sadler S, Holmes M, Ren S, Holden S, Jha S, Thokala P. Cost-effectiveness of antibiotic treatment of uncomplicated urinary tract infection in women: a comparison of four antibiotics. BJGP Open. 2017 Oct 04;1(3):bjgpopen17X101097. doi: 10.3399/bjgpopen17X101097. PMID: 30564681; PMCID: PMC6169925.
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Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia.

British journal of hospital medicine (London, England : 2005)

Gentry R, Tokala A, Wood H.
PMID: 34817264
Br J Hosp Med (Lond). 2021 Nov 02;82(11):1-3. doi: 10.12968/hmed.2021.0287. Epub 2021 Nov 23.

No abstract available.

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Gentry R, Tokala A, Wood H. Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia. Br J Hosp Med (Lond). 2021;82(11):1-3doi: 10.12968/hmed.2021.0287.
Gentry, R., Tokala, A., & Wood, H. (2021). Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia. British journal of hospital medicine (London, England : 2005), 82(11), 1-3. https://doi.org/10.12968/hmed.2021.0287
Gentry, Richard, et al. "Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia." British journal of hospital medicine (London, England : 2005) vol. 82,11 (2021): 1-3. doi: https://doi.org/10.12968/hmed.2021.0287
Gentry R, Tokala A, Wood H. Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia. Br J Hosp Med (Lond). 2021 Nov 02;82(11):1-3. doi: 10.12968/hmed.2021.0287. Epub 2021 Nov 23. PMID: 34817264.
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Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents.

Anti-cancer agents in medicinal chemistry

Yadav U, Vanjari Y, Laxmikeshav K, Tokala R, Niggula PK, Kumar M, Talla V, Kamal A, Shankaraiah N.
PMID: 32664846
Anticancer Agents Med Chem. 2021;21(9):1127-1140. doi: 10.2174/1871520620666200714142931.

OBJECTIVE: To synthesize a series of phenanthrene-thiazolidinedione hybrids and explore their cytotoxic potential against human cancer cell lines of A-549 (lung cancer), HCT-116 and HT-29 (colon cancer), MDA MB-231 (triple-negative breast cancer), BT-474 (breast cancer) and (mouse melanoma) B16F10...

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Yadav U, Vanjari Y, Laxmikeshav K, et al. Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents. Anticancer Agents Med Chem. 2021;21(9):1127-1140doi: 10.2174/1871520620666200714142931.
Yadav, U., Vanjari, Y., Laxmikeshav, K., Tokala, R., Niggula, P. K., Kumar, M., Talla, V., Kamal, A., & Shankaraiah, N. (2021). Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents. Anti-cancer agents in medicinal chemistry, 21(9), 1127-1140. https://doi.org/10.2174/1871520620666200714142931
Yadav, Upasana, et al. "Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents." Anti-cancer agents in medicinal chemistry vol. 21,9 (2021): 1127-1140. doi: https://doi.org/10.2174/1871520620666200714142931
Yadav U, Vanjari Y, Laxmikeshav K, Tokala R, Niggula PK, Kumar M, Talla V, Kamal A, Shankaraiah N. Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents. Anticancer Agents Med Chem. 2021;21(9):1127-1140. doi: 10.2174/1871520620666200714142931. PMID: 32664846.
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Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients.

Frontiers in pharmacology

Roggeveen LF, Guo T, Driessen RH, Fleuren LM, Thoral P, van der Voort PHJ, Girbes ARJ, Bosman RJ, Elbers P.
PMID: 32499697
Front Pharmacol. 2020 May 15;11:646. doi: 10.3389/fphar.2020.00646. eCollection 2020.

INTRODUCTION: Antibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but...

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Roggeveen LF, Guo T, Driessen RH, et al. Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients. Front Pharmacol. 2020;11:646doi: 10.3389/fphar.2020.00646.
Roggeveen, L. F., Guo, T., Driessen, R. H., Fleuren, L. M., Thoral, P., van der Voort, P. H. J., Girbes, A. R. J., Bosman, R. J., & Elbers, P. (2020). Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients. Frontiers in pharmacology, 11646. https://doi.org/10.3389/fphar.2020.00646
Roggeveen, Luca F, et al. "Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients." Frontiers in pharmacology vol. 11 (2020): 646. doi: https://doi.org/10.3389/fphar.2020.00646
Roggeveen LF, Guo T, Driessen RH, Fleuren LM, Thoral P, van der Voort PHJ, Girbes ARJ, Bosman RJ, Elbers P. Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients. Front Pharmacol. 2020 May 15;11:646. doi: 10.3389/fphar.2020.00646. eCollection 2020. PMID: 32499697; PMCID: PMC7243359.
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Early Noninvasive Cardiac Testing After Emergency Department Evaluation for Suspected Acute Coronary Syndrome.

JAMA internal medicine

Kawatkar AA, Sharp AL, Baecker AS, Natsui S, Redberg RF, Lee MS, Ferencik M, Wu YL, Shen E, Zheng C, Musigdilok VV, Gould MK, Goodacre S, Thokala P, Sun BC.
PMID: 33031502
JAMA Intern Med. 2020 Dec 01;180(12):1621-1629. doi: 10.1001/jamainternmed.2020.4325.

IMPORTANCE: Professional guidelines recommend noninvasive cardiac testing (NIT) within 72 hours of an emergency department (ED) evaluation for suspected acute coronary syndrome. However, there is inexact evidence that this strategy reduces the risk of future death or acute myocardial...

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Kawatkar AA, Sharp AL, Baecker AS, et al. Early Noninvasive Cardiac Testing After Emergency Department Evaluation for Suspected Acute Coronary Syndrome. JAMA Intern Med. 2020;180(12):1621-1629doi: 10.1001/jamainternmed.2020.4325.
Kawatkar, A. A., Sharp, A. L., Baecker, A. S., Natsui, S., Redberg, R. F., Lee, M. S., Ferencik, M., Wu, Y. L., Shen, E., Zheng, C., Musigdilok, V. V., Gould, M. K., Goodacre, S., Thokala, P., & Sun, B. C. (2020). Early Noninvasive Cardiac Testing After Emergency Department Evaluation for Suspected Acute Coronary Syndrome. JAMA internal medicine, 180(12), 1621-1629. https://doi.org/10.1001/jamainternmed.2020.4325
Kawatkar, Aniket A, et al. "Early Noninvasive Cardiac Testing After Emergency Department Evaluation for Suspected Acute Coronary Syndrome." JAMA internal medicine vol. 180,12 (2020): 1621-1629. doi: https://doi.org/10.1001/jamainternmed.2020.4325
Kawatkar AA, Sharp AL, Baecker AS, Natsui S, Redberg RF, Lee MS, Ferencik M, Wu YL, Shen E, Zheng C, Musigdilok VV, Gould MK, Goodacre S, Thokala P, Sun BC. Early Noninvasive Cardiac Testing After Emergency Department Evaluation for Suspected Acute Coronary Syndrome. JAMA Intern Med. 2020 Dec 01;180(12):1621-1629. doi: 10.1001/jamainternmed.2020.4325. PMID: 33031502; PMCID: PMC7536619.
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Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase.

Molecular therapy : the journal of the American Society of Gene Therapy

Durgin JS, Thokala R, Johnson L, Song E, Leferovich J, Bhoj V, Ghassemi S, Milone M, Binder Z, O'Rourke DM, O'Connor RS.
PMID: 34813961
Mol Ther. 2021 Nov 20; doi: 10.1016/j.ymthe.2021.11.014. Epub 2021 Nov 20.

Prior to adoptive transfer, CAR T cells are activated, lentivirally infected with CAR transgenes, and expanded over 9 to 11 days. An unintended consequence of this process is the progressive differentiation of CAR T cells over time in culture....

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Durgin JS, Thokala R, Johnson L, et al. Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase. Mol Ther. 2021;doi: 10.1016/j.ymthe.2021.11.014.
Durgin, J. S., Thokala, R., Johnson, L., Song, E., Leferovich, J., Bhoj, V., Ghassemi, S., Milone, M., Binder, Z., O'Rourke, D. M., & O'Connor, R. S. (2021). Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase. Molecular therapy : the journal of the American Society of Gene Therapy, . https://doi.org/10.1016/j.ymthe.2021.11.014
Durgin, Joseph S, et al. "Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase." Molecular therapy : the journal of the American Society of Gene Therapy vol. (2021). doi: https://doi.org/10.1016/j.ymthe.2021.11.014
Durgin JS, Thokala R, Johnson L, Song E, Leferovich J, Bhoj V, Ghassemi S, Milone M, Binder Z, O'Rourke DM, O'Connor RS. Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase. Mol Ther. 2021 Nov 20; doi: 10.1016/j.ymthe.2021.11.014. Epub 2021 Nov 20. PMID: 34813961.
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Recovery of Platelet Count among Apheresis Platelet Donors.

Journal of clinical and diagnostic research : JCDR

Thokala RP, Radhakrishnan K, Anandan A, Panicker VK.
PMID: 28208861
J Clin Diagn Res. 2016 Dec;10(12):EC01-EC04. doi: 10.7860/JCDR/2016/21070.8997. Epub 2016 Dec 01.

INTRODUCTION: Increase in awareness regarding use of single donor platelets and the availability of technology has resulted in increased platelet pheresis procedures. The interval between two succesive plateletpheresis donations is much less compared to whole blood donations. Plateletpheresis procedures...

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Thokala RP, Radhakrishnan K, Anandan A, et al. Recovery of Platelet Count among Apheresis Platelet Donors. J Clin Diagn Res. 2016;10(12):EC01-EC04doi: 10.7860/JCDR/2016/21070.8997.
Thokala, R. P., Radhakrishnan, K., Anandan, A., & Panicker, V. K. (2016). Recovery of Platelet Count among Apheresis Platelet Donors. Journal of clinical and diagnostic research : JCDR, 10(12), EC01-EC04. https://doi.org/10.7860/JCDR/2016/21070.8997
Thokala, Ravindra Prasad, et al. "Recovery of Platelet Count among Apheresis Platelet Donors." Journal of clinical and diagnostic research : JCDR vol. 10,12 (2016): EC01-EC04. doi: https://doi.org/10.7860/JCDR/2016/21070.8997
Thokala RP, Radhakrishnan K, Anandan A, Panicker VK. Recovery of Platelet Count among Apheresis Platelet Donors. J Clin Diagn Res. 2016 Dec;10(12):EC01-EC04. doi: 10.7860/JCDR/2016/21070.8997. Epub 2016 Dec 01. PMID: 28208861; PMCID: PMC5296434.
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Showing 1 to 12 of 81 entries