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Showing 1 to 12 of 21 entries
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Implementing a structured education program for children with diabetes: lessons learnt from an integrated process evaluation.

BMJ open diabetes research & care

Sawtell M, Jamieson L, Wiggins M, Smith F, Ingold A, Hargreaves K, Khatwa M, Brooks L, Thompson R, Christie D.
PMID: 25969740
BMJ Open Diabetes Res Care. 2015 Apr 28;3(1):e000065. doi: 10.1136/bmjdrc-2014-000065. eCollection 2015.

BACKGROUND: There is recognition of an urgent need for clinic-based interventions for young people with type 1 diabetes mellitus that improve glycemic control and quality of life. The Child and Adolescent Structured Competencies Approach to Diabetes Education (CASCADE) is...

Smartphone Apps Provide a Simple, Accurate Bedside Screening Tool for Orthostatic Tremor.

Movement disorders clinical practice

Bhatti D, Thompson R, Hellman A, Penke C, Bertoni JM, Torres-Russotto D.
PMID: 30363432
Mov Disord Clin Pract. 2017 Oct 08;4(6):852-857. doi: 10.1002/mdc3.12547. eCollection 2017.

BACKGROUND: Orthostatic Tremor (OT) is characterized by the presence of a sensation of instability while standing, associated with high frequency (13-18 Hz) lower extremity tremor. Diagnosis is confirmed with surface electromyography (EMG). An accurate screening tool that could be...

Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence.

Chemical science

Reddington SC, Baldwin AJ, Thompson R, Brancale A, Tippmann EM, Jones DD.
PMID: 29560203
Chem Sci. 2015 Feb 01;6(2):1159-1166. doi: 10.1039/c4sc02827a. Epub 2014 Nov 07.

Genetic code reprogramming allows proteins to sample new chemistry through the defined and targeted introduction of non-natural amino acids (nAAs). Many useful nAAs are derivatives of the natural aromatic amino acid tyrosine, with the

Evacuation from Natural Disasters: A Systematic Review of the Literature.

Risk analysis : an official publication of the Society for Risk Analysis

Thompson RR, Garfin DR, Silver RC.
PMID: 28000928
Risk Anal. 2017 Apr;37(4):812-839. doi: 10.1111/risa.12654. Epub 2016 Dec 21.

Research on evacuation from natural disasters has been published across the peer-reviewed literature among several disparate disciplinary outlets and has suggested a wide variety of predictors of evacuation behavior. We conducted a systematic review to summarize and evaluate the...

Structures of .

Science advances

Swainsbury DJK, Qian P, Jackson PJ, Faries KM, Niedzwiedzki DM, Martin EC, Farmer DA, Malone LA, Thompson RF, Ranson NA, Canniffe DP, Dickman MJ, Holten D, Kirmaier C, Hitchcock A, Hunter CN.
PMID: 33523887
Sci Adv. 2021 Jan 13;7(3). doi: 10.1126/sciadv.abe2631. Print 2021 Jan.

The reaction-center light-harvesting complex 1 (RC-LH1) is the core photosynthetic component in purple phototrophic bacteria. We present two cryo-electron microscopy structures of RC-LH1 complexes from

Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.

Cell reports

Pal M, Muñoz-Hernandez H, Bjorklund D, Zhou L, Degliesposti G, Skehel JM, Hesketh EL, Thompson RF, Pearl LH, Llorca O, Prodromou C.
PMID: 34233195
Cell Rep. 2021 Jul 06;36(1):109317. doi: 10.1016/j.celrep.2021.109317.

The R2TP (RUVBL1-RUVBL2-RPAP3-PIH1D1) complex, in collaboration with heat shock protein 90 (HSP90), functions as a chaperone for the assembly and stability of protein complexes, including RNA polymerases, small nuclear ribonucleoprotein particles (snRNPs), and phosphatidylinositol 3-kinase (PI3K)-like kinases (PIKKs) such...

Genome sequence and comparative genome analysis of Lactobacillus casei: insights into their niche-associated evolution.

Genome biology and evolution

Cai H, Thompson R, Budinich MF, Broadbent JR, Steele JL.
PMID: 20333194
Genome Biol Evol. 2009 Jul 14;1:239-57. doi: 10.1093/gbe/evp019.

Lactobacillus casei is remarkably adaptable to diverse habitats and widely used in the food industry. To reveal the genomic features that contribute to its broad ecological adaptability and examine the evolution of the species, the genome sequence of L....

Haemoptysis in pregnancy caused by a well-differentiated fetal adenocarcinoma: a case report.

Journal of medical case reports

Thompson RJ, Hasleton PS, Taylor PM, Woodhead M, Byrd LM.
PMID: 20205788
J Med Case Rep. 2010 Jan 20;4:17. doi: 10.1186/1752-1947-4-17.

INTRODUCTION: Haemoptysis in pregnancy is frequently assumed to be caused by a pulmonary embolism. However, it can also be an indicator of serious pathology.CASE PRESENTATION: We report the case of a 27-year-old Caucasian woman who presented with haemoptysis in...

Distress and rumor exposure on social media during a campus lockdown.

Proceedings of the National Academy of Sciences of the United States of America

Jones NM, Thompson RR, Dunkel Schetter C, Silver RC.
PMID: 29042513
Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11663-11668. doi: 10.1073/pnas.1708518114. Epub 2017 Oct 17.

During crisis events, people often seek out event-related information to stay informed of what is happening. However, when information from official channels is lacking or disseminated irregularly, people may be at risk for exposure to rumors that fill the...

Managing the cancer-work interface: the effect of cancer survivorship on unemployment.

Cancer management and research

Tracy JK, Falk D, Thompson RJ, Scheindlin L, Adetunji F, Swanberg JE.
PMID: 30568507
Cancer Manag Res. 2018 Nov 28;10:6479-6487. doi: 10.2147/CMAR.S180649. eCollection 2018.

OBJECTIVE: This study assessed differences in employment outcomes among cancer survivors using data from a nationally representative sample.METHODS: The 2011 Medical Expenditure Panel Survey (MEPS) data and the 2011 MEPS Experiences with Cancer Survivorship Supplement representing 3,360,465 people in...

A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury.

Cell reports. Medicine

Kost-Alimova M, Sidhom EH, Satyam A, Chamberlain BT, Dvela-Levitt M, Melanson M, Alper SL, Santos J, Gutierrez J, Subramanian A, Byrne PJ, Grinkevich E, Reyes-Bricio E, Kim C, Clark AR, Watts AJB, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A.
PMID: 33294858
Cell Rep Med. 2020 Oct 29;1(8):100137. doi: 10.1016/j.xcrm.2020.100137. eCollection 2020 Nov 17.

Drug repurposing has the advantage of identifying potential treatments on a shortened timescale. In response to the pandemic spread of SARS-CoV-2, we took advantage of a high-content screen of 3,713 compounds at different stages of clinical development to identify...

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic.

bioRxiv : the preprint server for biology

Alimova M, Sidhom EH, Satyam A, Dvela-Levitt M, Melanson M, Chamberlain BT, Alper SL, Santos J, Gutierrez J, Subramanian A, Grinkevich E, Bricio ER, Kim C, Clark A, Watts A, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A.
PMID: 32637960
bioRxiv. 2020 Jun 30; doi: 10.1101/2020.06.30.180380.

Drug repurposing is the only method capable of delivering treatments on the shortened time-scale required for patients afflicted with lung disease arising from SARS-CoV-2 infection. Mucin-1 (MUC1), a membrane-bound molecule expressed on the apical surfaces of most mucosal epithelial...

Showing 1 to 12 of 21 entries