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Showing 1 to 12 of 164 entries
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Patient-reported symptoms at hospital discharge independently can predict death and hospitalization burden in advanced heart failure.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Alpert CM, Hummel EK, Koelling TM, Palardy M, Hummel SL.
PMID: 29129370
J Heart Lung Transplant. 2017 Oct 23; doi: 10.1016/j.healun.2017.10.013. Epub 2017 Oct 23.

No abstract available.

Estimating maximum horizontal area of pheromone plumes.

Journal of chemical ecology

Stanley BH, Hummel HE, Ruesink WG.
PMID: 24310335
J Chem Ecol. 1985 Aug;11(8):1129-46. doi: 10.1007/BF01020680.

Graphs and simple Gaussian plume equations are presented for estimating the maximum horizontal area within a pheromone plume. In its simplest form the area,A R , for a given scaling factor,R = Q/(Ku), isA R = AI R (β),...

Developing a prototype system for integrating pharmacogenomics findings into clinical practice.

Journal of personalized medicine

Overby CL, Tarczy-Hornoch P, Kalet IJ, Thummel KE, Smith JW, Del Fiol G, Fenstermacher D, Devine EB.
PMID: 23741623
J Pers Med. 2012 Nov 20;2(4):241-56. doi: 10.3390/jpm2040241.

Findings from pharmacogenomics (PGx) studies have the potential to be applied to individualize drug therapy to improve efficacy and reduce adverse drug events. Researchers have identified factors influencing uptake of genomics in medicine, but little is known about the...

Diastereoselective Formation and Photophysical Behavior of a Chiral Copper(I) Phenanthroline Complex.

Inorganic chemistry

Riesgo EC, Credi A, De Cola L, Thummel RP.
PMID: 11670368
Inorg Chem. 1998 May 04;37(9):2145-2149. doi: 10.1021/ic971267a.

The Friedländer condensation of (1R,5S)-(+)- and (1S,5R)-(-)-nopinone with 8-aminoquinoline-7-carbaldehyde leads to the corresponding enantiomerically pure (2,3-b)-pineno-1,10-phenanthrolines. Coordination of these ligands with Cu(I) affords non-interconvertable chiral complexes which show equal and opposite Cotton effects in their CD spectra as well...

Ruthenium(II) Complexes of 2-Aryl-1,10-phenanthrolines: Synthesis, Structure, and Photophysical Properties.

Inorganic chemistry

Wu F, Riesgo E, Pavalova A, Kipp RA, Schmehl RH, Thummel RP.
PMID: 11671292
Inorg Chem. 1999 Nov 29;38(24):5620-5628. doi: 10.1021/ic990706y.

The synthesis, characterization, and photochemical investigation of a series of Ru(II) complexes having 2-phenyl- and 2,9-diphenyl substituted phenanthroline ligands are reported. Structural characterization of some of the complexes revealed that the phenyl substituents of the phenanthroline ligand are oriented...

Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction.

Advanced drug delivery reviews

Shen DD, Kunze KL, Thummel KE.
PMID: 10837554
Adv Drug Deliv Rev. 1997 Sep 15;27(2):99-127. doi: 10.1016/s0169-409x(97)00039-2.

Oral bioavailability of pharmacologically effective drugs is often limited by first-pass biotransformation. In humans, both hepatic and intestinal enzymes can catalyze the metabolism of a drug as it transits between the gastrointestinal lumen and systemic blood for the first...

Friedländer approach for the incorporation of 6-bromoquinoline into novel chelating ligands.

Organic letters

Hu YZ, Zhang G, Thummel RP.
PMID: 12816421
Org Lett. 2003 Jun 26;5(13):2251-3. doi: 10.1021/ol034559q.

Nitration of 3-bromobenzaldehyde followed by sodium dithionite reduction provides 5-bromo-2-aminobenzaldehyde, which undergoes the Friedländer condensation with a variety of enolizable ketones to afford bidentate and tridentate 6-bromoquinoline derivatives. These species may be dimerized with Ni(0) to form biquinolines or...

Young Produced from Ovaries Subjected to Endocrine Imbalance.

Proceedings of the National Academy of Sciences of the United States of America

Little CC, Hummel KP, Eddy M, Rupple B.
PMID: 16578398
Proc Natl Acad Sci U S A. 1951 Oct;37(10):666-9. doi: 10.1073/pnas.37.10.666.

No abstract available.

Preparation and study of a family of dinuclear Ru(II) complexes that catalyze the decomposition of water.

Inorganic chemistry

Deng Z, Tseng HW, Zong R, Wang D, Thummel R.
PMID: 18330974
Inorg Chem. 2008 Mar 17;47(6):1835-48. doi: 10.1021/ic7010875.

An approach is developed for the four-electron oxidation of water to provide dioxygen that involves the juxtaposition of two Ru(II) centers such that a metal-bound water molecule might interact with one or both of the metals. The key element...

2,9-Di-(2'-pyridyl)-1,10-phenanthroline: a tetradentate ligand for Ru(II).

Journal of the American Chemical Society

Zong R, Thummel RP.
PMID: 15339138
J Am Chem Soc. 2004 Sep 08;126(35):10800-1. doi: 10.1021/ja047410y.

The tetradentate ligand 2,9-di-(2'-pyridyl)-1,10-phenanthroline is synthesized in 62% yield by the Stille coupling of 2,9-dichloro-1,10-phenanthroline and 2-(tri-n-butylstannyl)pyridine. Treatment of this ligand with RuCl3.3H2O and a 4-substituted pyridine results in the formation of a complex in which the tetradentate ligand...

Proton transfer with a twist? Femtosecond dynamics of 7-(2-pyridyl)indole in condensed phase and in supersonic jets.

Angewandte Chemie (International ed. in English)

Nosenko Y, Wiosna-Sałyga G, Kunitski M, Petkova I, Singh A, Buma WJ, Thummel RP, Brutschy B, Waluk J.
PMID: 18604789
Angew Chem Int Ed Engl. 2008;47(32):6037-40. doi: 10.1002/anie.200801350.

No abstract available.

Evidence That Ceriporiopsis subvermispora Degrades Nonphenolic Lignin Structures by a One-Electron-Oxidation Mechanism.

Applied and environmental microbiology

Srebotnik E, Jensen KA, Kawai S, Hammel KE.
PMID: 16535732
Appl Environ Microbiol. 1997 Nov;63(11):4435-40. doi: 10.1128/aem.63.11.4435-4440.1997.

The white-rot fungus Ceriporiopsis subvermispora is able to degrade nonphenolic lignin structures but appears to lack lignin peroxidase (LiP), which is generally thought to be responsible for these reactions. It is well established that LiP-producing fungi such as Phanerochaete...

Showing 1 to 12 of 164 entries