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Showing 1 to 12 of 69 entries
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Promising oncolytic agents for metastatic breast cancer treatment.

Oncolytic virotherapy

Cody JJ, Hurst DR.
PMID: 27512671
Oncolytic Virother. 2015 Jun 03;4:63-73. doi: 10.2147/OV.S63045. eCollection 2015.

New therapies for metastatic breast cancer patients are urgently needed. The long-term survival rates remain unacceptably low for patients with recurrent disease or disseminated metastases. In addition, existing therapies often cause a variety of debilitating side effects that severely...

Increased autophagic response in a population of metastatic breast cancer cells.

Oncology letters

Li YI, Libby EF, Lewis MJ, Liu J, Shacka JJ, Hurst DR.
PMID: 27347175
Oncol Lett. 2016 Jul;12(1):523-529. doi: 10.3892/ol.2016.4613. Epub 2016 May 24.

Breast cancer cells are heterogeneous in their ability to invade and fully metastasize, and thus also in their capacity to survive the numerous stresses encountered throughout the multiple steps of the metastatic cascade. Considering the role of autophagy as...

Developing the careers of clinician-educators in psychiatry.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

Bennett AJ, Clardy JA, Cargile CS, Thrush CR.
PMID: 17242053
Acad Psychiatry. 2007 Jan-Feb;31(1):57-60. doi: 10.1176/appi.ap.31.1.57.

OBJECTIVE: This article describes initial efforts by the newly developed Clinician-Educator Section (CES) of the Association for Academic Psychiatry (AAP) to support the career advancement of academic faculty within psychiatry. The CES provided its first workshop at the 2005...

Relative delay of reinforcement and choice.

Journal of the experimental analysis of behavior

Hursh SR, Fantino E.
PMID: 16811674
J Exp Anal Behav. 1973 May;19(3):437-50. doi: 10.1901/jeab.1973.19-437.

Pigeons' responses on either of two concurrently available keys each associated with variable-interval 60-sec schedules occasionally changed the schedule on that key to a terminal-link interval schedule providing access to gain while the other key became inoperative. Experiment I...

"Automaintenance": the role of reinforcement.

Journal of the experimental analysis of behavior

Hursh SR, Navarick DJ, Fantino E.
PMID: 16811725
J Exp Anal Behav. 1974 Jan;21(1):117-24. doi: 10.1901/jeab.1974.21-117.

A key was illuminated on the average of every 30 sec for a duration of 6 sec and this was followed by food presentations. When key pecks in the presence of the light produced immediate access to grain (autoshaping...

Reviewers' comments on Timberlake's "Behavior regulation and learned performance".

Journal of the experimental analysis of behavior

Hursh SR, Case D, Mazur JE, Fantino E, Branch M, Shull RL.
PMID: 16812375
J Exp Anal Behav. 1984 May;41(3):376-82. doi: 10.1901/jeab.1984.41-376.

No abstract available.

The economics of daily consumption controlling food- and water-reinforced responding.

Journal of the experimental analysis of behavior

Hursh SR.
PMID: 16812071
J Exp Anal Behav. 1978 May;29(3):475-91. doi: 10.1901/jeab.1978.29-475.

In the first experiment, two rhesus monkeys earned their entire ration of food and water during daily sessions with no provisions to ensure constant daily intakes. Two variable-interval schedules of food presentations were concurrent with one variable-interval schedule of...

POSITIVE GAS AND WATER PRESSURE IN OAKS.

Science (New York, N.Y.)

Abell CA, Hursh CR.
PMID: 17810892
Science. 1931 Apr 24;73(1895):449. doi: 10.1126/science.73.1895.449.

No abstract available.

Autosomal dominant pseudohypoaldosteronism type 1 in an infant with salt wasting crisis associated with urinary tract infection and obstructive uropathy.

Case reports in endocrinology

Bowden SA, Cozzi C, Hickey SE, Thrush DL, Astbury C, Nuthakki S.
PMID: 24455331
Case Rep Endocrinol. 2013;2013:524647. doi: 10.1155/2013/524647. Epub 2013 Dec 19.

Type 1 pseudohypoaldosteronism (PHA1) is a salt wasting syndrome caused by renal resistance to aldosterone. Primary renal PHA1 or autosomal dominant PHA1 is caused by mutations in mineralocorticoids receptor gene (NR3C2), while secondary PHA1 is frequently associated with urinary...

Suppressor CD4.

Gut

Khamri W, Gudd C, Liu T, Nathwani R, Krasniqi M, Azam S, Barbera T, Trovato FM, Possamai L, Triantafyllou E, Seoane RC, Lebosse F, Singanayagam A, Kumar N, Bernsmeier C, Mukherjee S, McPhail M, Weston CJ, Antoniades CG, Thursz MR.
PMID: 34344786
Gut. 2021 Aug 03; doi: 10.1136/gutjnl-2021-324071. Epub 2021 Aug 03.

OBJECTIVE: Identifying components of immuneparesis, a hallmark of chronic liver failure, is crucial for our understanding of complications in cirrhosis. Various suppressor CD4DESIGN: Flow cytometry was used to determine the proportion and immunophenotype of CD4RESULTS: Patients with AD were...

Activation and transcriptional profile of monocytes and CD8.

Journal of hepatology

Gudd CLC, Au L, Triantafyllou E, Shum B, Liu T, Nathwani R, Kumar N, Mukherjee S, Dhar A, Woollard KJ, Yone Y, Pinato DJ, Thursz MR, Goldin RD, Gore ME, Larkin J, Khamri W, Antoniades CG, Turajlic S, Possamai LA.
PMID: 33631227
J Hepatol. 2021 Jul;75(1):177-189. doi: 10.1016/j.jhep.2021.02.008. Epub 2021 Feb 22.

BACKGROUND & AIMS: Checkpoint inhibitor-related hepatitis (CPI-Hep) is an emerging clinical challenge. We aimed to gain insights into the immunopathology of CPI-Hep by comprehensively characterising myeloid and lymphoid subsets.METHODS: CPI-treated patients with or without related hepatitis (CPI-Hep; n =...

Pilot Sleep Behavior across Time during Ultra-Long-Range Flights.

Clocks & sleep

Devine JK, Choynowski J, Garcia CR, Simoes AS, Guelere MR, Godoy B, Silva DS, Pacheco P, Hursh SR.
PMID: 34698137
Clocks Sleep. 2021 Sep 23;3(4):515-527. doi: 10.3390/clockssleep3040036.

Fatigue risk to the pilot has been a deterrent for conducting direct flights longer than 12 h under normal conditions, but such flights were a necessity during the COVID-19 pandemic. Twenty (N = 20) pilots flying across five humanitarian...

Showing 1 to 12 of 69 entries