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Showing 1 to 4 of 4 entries
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Bioequivalence of two formulations of montelukast sodium 4 mg oral granules in healthy adults.

Clinical and translational allergy

Fey C, Thyroff-Friesinger U, Jones S.
PMID: 25250173
Clin Transl Allergy. 2014 Sep 18;4:29. doi: 10.1186/2045-7022-4-29. eCollection 2014.

Montelukast is an effective and well-tolerated treatment for the prophylaxis and chronic treatment of asthma, acute prevention of exercise-induced bronchoconstriction and symptomatic relief of seasonal allergic rhinitis and perennial allergic rhinitis. The aim of the study was to compare...

Clinical development of two innovative pharmaceutical forms of leuprorelin acetate.

Therapeutic advances in urology

Geiges G, Schapperer E, Thyroff-Friesinger U, Engert ZV, Gravel P.
PMID: 23372606
Ther Adv Urol. 2013 Feb;5(1):3-10. doi: 10.1177/1756287212471096.

OBJECTIVES: Two innovative pharmaceutical forms of leuprorelin acetate have been developed as 1-month and 3-month implants for the treatment of advanced hormone-dependent prostate cancer. These products contain active substance dispersed homogeneously in a biodegradable polymer. Here we present the...

Bioequivalence of Sandoz methylphenidate osmotic-controlled release tablet with Concerta® (Janssen-Cilag).

Pharmacology research & perspectives

Schapperer E, Daumann H, Lamouche S, Thyroff-Friesinger U, Viel F, Weitschies W.
PMID: 25692005
Pharmacol Res Perspect. 2015 Feb;3(1):e00072. doi: 10.1002/prp2.72. Epub 2015 Jan 05.

The aim was to assess the bioequivalence of Sandoz methylphenidate osmotic-controlled release (OCR) tablets (Sandoz [Methylphenidate[ MPH OCR) with Concerta®, a methylphenidate formulation indicated for the treatment of attention deficit/hyperactivity disorder (ADHD). Four open-label, randomized, single-dose, two-way crossover bioequivalence...

Testosterone suppression with a unique form of leuprorelin acetate as a solid biodegradable implant in patients with advanced prostate cancer: results from four trials and comparison with the traditional leuprorelin acetate microspheres formulation.

Therapeutic advances in urology

Solarić M, Bjartell A, Thyroff-Friesinger U, Meani D.
PMID: 28588651
Ther Adv Urol. 2017 Apr 18;9(6):127-136. doi: 10.1177/1756287217701665. eCollection 2017 Dec.

BACKGROUND: There are two slow-release ready-to-use forms of leuprorelin acetate (1-month and 3-month) that are available as solid, biodegradable implants for the treatment of advanced, hormone-sensitive prostate cancer. These implants have been shown to be as effective as traditional...

Showing 1 to 4 of 4 entries