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Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine.

Evidence-based complementary and alternative medicine : eCAM

Tan S, Tillisch K, Mayer E.
PMID: 15257324
Evid Based Complement Alternat Med. 2004 Jun 01;1(1):35-40. doi: 10.1093/ecam/neh016.

The so-called functional somatic syndromes comprise a group of disorders that are primarily symptom-based, multisystemic in presentation and probably involve alterations in mind-brain-body interactions. The emerging neurobiological models of allostasis/allostatic load and of the emotional motor system show striking...

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Tan S, Tillisch K, Mayer E. Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine. Evid Based Complement Alternat Med. 2004;1(1):35-40doi: 10.1093/ecam/neh016.
Tan, S., Tillisch, K., & Mayer, E. (2004). Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine. Evidence-based complementary and alternative medicine : eCAM, 1(1), 35-40. https://doi.org/10.1093/ecam/neh016
Tan, Steven, et al. "Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine." Evidence-based complementary and alternative medicine : eCAM vol. 1,1 (2004): 35-40. doi: https://doi.org/10.1093/ecam/neh016
Tan S, Tillisch K, Mayer E. Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine. Evid Based Complement Alternat Med. 2004 Jun 01;1(1):35-40. doi: 10.1093/ecam/neh016. PMID: 15257324; PMCID: PMC442118.
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On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study.

Journal of neurogastroenterology and motility

Simon RA, Engström M, Icenhour A, Lowén M, Ström M, Tillisch K, Mayer E, Elsenbruch S, Walter S.
PMID: 31327225
J Neurogastroenterol Motil. 2019 Jul 01;25(3):478-479. doi: 10.5056/jnm19069.

No abstract available.

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Simon RA, Engström M, Icenhour A, et al. On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study. J Neurogastroenterol Motil. 2019;25(3):478-479doi: 10.5056/jnm19069.
Simon, R. A., Engström, M., Icenhour, A., Lowén, M., Ström, M., Tillisch, K., Mayer, E., Elsenbruch, S., & Walter, S. (2019). On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study. Journal of neurogastroenterology and motility, 25(3), 478-479. https://doi.org/10.5056/jnm19069
Simon, Rozalyn A, et al. "On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study." Journal of neurogastroenterology and motility vol. 25,3 (2019): 478-479. doi: https://doi.org/10.5056/jnm19069
Simon RA, Engström M, Icenhour A, Lowén M, Ström M, Tillisch K, Mayer E, Elsenbruch S, Walter S. On Functional Connectivity and Symptom Relief After Gut-directed Hypnotherapy in Irritable Bowel Syndrome: A Preliminary Study. J Neurogastroenterol Motil. 2019 Jul 01;25(3):478-479. doi: 10.5056/jnm19069. PMID: 31327225; PMCID: PMC6657922.
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Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Lenhart A, Dong T, Joshi S, Jaffe N, Choo C, Liu C, Jacobs JP, Lagishetty V, Shih W, Labus JS, Gupta A, Tillisch K, Mayer EA, Chang L.
PMID: 34022450
Clin Gastroenterol Hepatol. 2021 May 20; doi: 10.1016/j.cgh.2021.05.027. Epub 2021 May 20.

BACKGROUND & AIMS: Altered fecal microbiota have been reported in irritable bowel syndrome (IBS), although studies vary, which could be owing to dietary effects. Many IBS patients may eliminate certain foods because of their symptoms, which in turn may...

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Lenhart A, Dong T, Joshi S, et al. Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2021;doi: 10.1016/j.cgh.2021.05.027.
Lenhart, A., Dong, T., Joshi, S., Jaffe, N., Choo, C., Liu, C., Jacobs, J. P., Lagishetty, V., Shih, W., Labus, J. S., Gupta, A., Tillisch, K., Mayer, E. A., & Chang, L. (2021). Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, . https://doi.org/10.1016/j.cgh.2021.05.027
Lenhart, Adrienne, et al. "Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association vol. (2021). doi: https://doi.org/10.1016/j.cgh.2021.05.027
Lenhart A, Dong T, Joshi S, Jaffe N, Choo C, Liu C, Jacobs JP, Lagishetty V, Shih W, Labus JS, Gupta A, Tillisch K, Mayer EA, Chang L. Effect of Exclusion Diets on Symptom Severity and the Gut Microbiota in Patients With Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2021 May 20; doi: 10.1016/j.cgh.2021.05.027. Epub 2021 May 20. PMID: 34022450.
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Significance of combined blood phosphatase and sedimentation rate in the diagnosis of metastatic carcinoma of the prostate (transl.).

America clinica

BOYLAN RN, TILLISCH JH.
PMID: 18099008
Am Clin. 1948 Nov;13(5):402.

No abstract available.

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BOYLAN RN, TILLISCH JH. Significado de la fosfatasa combinada de la sangre y de la velocidad de sedimentación el el diagnóstico de las metástasis del carcinoma de la próstata (transl.). Significance of combined blood phosphatase and sedimentation rate in the diagnosis of metastatic carcinoma of the prostate (transl.). Am Clin. 1948;13(5):402
BOYLAN, R. N., & TILLISCH, J. H. (1948). Significado de la fosfatasa combinada de la sangre y de la velocidad de sedimentación el el diagnóstico de las metástasis del carcinoma de la próstata (transl.). Significance of combined blood phosphatase and sedimentation rate in the diagnosis of metastatic carcinoma of the prostate (transl.). America clinica, 13(5), 402.
BOYLAN, R N, and TILLISCH, J H. "Significado de la fosfatasa combinada de la sangre y de la velocidad de sedimentación el el diagnóstico de las metástasis del carcinoma de la próstata (transl.)." Significance of combined blood phosphatase and sedimentation rate in the diagnosis of metastatic carcinoma of the prostate (transl.). America clinica vol. 13,5 (1948): 402.
BOYLAN RN, TILLISCH JH. Significado de la fosfatasa combinada de la sangre y de la velocidad de sedimentación el el diagnóstico de las metástasis del carcinoma de la próstata (transl.). Significance of combined blood phosphatase and sedimentation rate in the diagnosis of metastatic carcinoma of the prostate (transl.). Am Clin. 1948 Nov;13(5):402. Spanish. PMID: 18099008.
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Centrally Mediated Disorders of Gastrointestinal Pain.

Gastroenterology

Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ.
PMID: 27144628
Gastroenterology. 2016 Feb 19; doi: 10.1053/j.gastro.2016.02.034. Epub 2016 Feb 19.

Centrally Mediated Abdominal Pain Syndrome (CAPS), formerly known as Functional Abdominal Pain Syndrome, can be distinguished from other functional GI disorders by its strong central component and relative independence from motility disturbances. CAPS is a result of central sensitization...

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Keefer L, Drossman DA, Guthrie E, et al. Centrally Mediated Disorders of Gastrointestinal Pain. Gastroenterology. 2016;doi: 10.1053/j.gastro.2016.02.034.
Keefer, L., Drossman, D. A., Guthrie, E., Simrén, M., Tillisch, K., Olden, K., & Whorwell, P. J. (2016). Centrally Mediated Disorders of Gastrointestinal Pain. Gastroenterology, . https://doi.org/10.1053/j.gastro.2016.02.034
Keefer, Laurie, et al. "Centrally Mediated Disorders of Gastrointestinal Pain." Gastroenterology vol. (2016). doi: https://doi.org/10.1053/j.gastro.2016.02.034
Keefer L, Drossman DA, Guthrie E, Simrén M, Tillisch K, Olden K, Whorwell PJ. Centrally Mediated Disorders of Gastrointestinal Pain. Gastroenterology. 2016 Feb 19; doi: 10.1053/j.gastro.2016.02.034. Epub 2016 Feb 19. PMID: 27144628.
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Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts.

BMJ open gastroenterology

Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J, Heath GW, Parra DC, Sarmiento OL.
PMID: 28761687
BMJ Open Gastroenterol. 2017 Apr 01;4(1):e000134. doi: 10.1136/bmjgast-2017-000134. eCollection 2017.

OBJECTIVE: To compare faecal microbial composition in patients with systemic sclerosis (SSc) from 2 independent cohorts with controls and to determine whether certain genera are associated with SSc-gastrointestinal tract (GIT) symptoms.DESIGN: Adult patients with SSc from the University of...

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Volkmann ER, Hoffmann-Vold AM, Chang YL, et al. Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. BMJ Open Gastroenterol. 2017;4(1):e000134doi: 10.1136/bmjgast-2017-000134.
Volkmann, E. R., Hoffmann-Vold, A. M., Chang, Y. L., Jacobs, J. P., Tillisch, K., Mayer, E. A., Clements, P. J., Hov, J. R., Kummen, M., Midtvedt, �. �., Lagishetty, V., Chang, L., Labus, J. S., Molberg, �. �., Braun, J., Heath, G. W., Parra, D. C., & Sarmiento, O. L. (2017). Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. BMJ open gastroenterology, 4(1), e000134. https://doi.org/10.1136/bmjgast-2017-000134
Volkmann, Elizabeth R, et al. "Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts." BMJ open gastroenterology vol. 4,1 (2017): e000134. doi: https://doi.org/10.1136/bmjgast-2017-000134
Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J, Heath GW, Parra DC, Sarmiento OL. Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. BMJ Open Gastroenterol. 2017 Apr 01;4(1):e000134. doi: 10.1136/bmjgast-2017-000134. eCollection 2017. PMID: 28761687; PMCID: PMC5508636.
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History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity.

Obesity science & practice

Osadchiy V, Mayer EA, Bhatt R, Labus JS, Gao L, Kilpatrick LA, Liu C, Tillisch K, Naliboff B, Chang L, Gupta A.
PMID: 31687167
Obes Sci Pract. 2019 Aug 30;5(5):416-436. doi: 10.1002/osp4.362. eCollection 2019 Oct.

BACKGROUND: Neuroimaging studies have identified obesity-related differences in the brain's resting state activity. An imbalance between homeostatic and reward aspects of ingestive behaviour may contribute to obesity and food addiction. The interactions between early life adversity (ELA), the reward...

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Osadchiy V, Mayer EA, Bhatt R, et al. History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity. Obes Sci Pract. 2019;5(5):416-436doi: 10.1002/osp4.362.
Osadchiy, V., Mayer, E. A., Bhatt, R., Labus, J. S., Gao, L., Kilpatrick, L. A., Liu, C., Tillisch, K., Naliboff, B., Chang, L., & Gupta, A. (2019). History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity. Obesity science & practice, 5(5), 416-436. https://doi.org/10.1002/osp4.362
Osadchiy, V, et al. "History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity." Obesity science & practice vol. 5,5 (2019): 416-436. doi: https://doi.org/10.1002/osp4.362
Osadchiy V, Mayer EA, Bhatt R, Labus JS, Gao L, Kilpatrick LA, Liu C, Tillisch K, Naliboff B, Chang L, Gupta A. History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity. Obes Sci Pract. 2019 Aug 30;5(5):416-436. doi: 10.1002/osp4.362. eCollection 2019 Oct. PMID: 31687167; PMCID: PMC6819979.
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Description of a quantum convolutional code.

Physical review letters

Ollivier H, Tillich JP.
PMID: 14611378
Phys Rev Lett. 2003 Oct 24;91(17):177902. doi: 10.1103/PhysRevLett.91.177902. Epub 2003 Oct 23.

We describe a quantum error correction scheme aimed at protecting a flow of quantum information over long distance communication. It is largely inspired by the theory of classical convolutional codes which are used in similar circumstances in classical communication....

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Ollivier H, Tillich JP. Description of a quantum convolutional code. Phys Rev Lett. 2003;91(17):177902doi: 10.1103/PhysRevLett.91.177902.
Ollivier, H., & Tillich, J. P. (2003). Description of a quantum convolutional code. Physical review letters, 91(17), 177902. https://doi.org/10.1103/PhysRevLett.91.177902
Ollivier, Harold, and Tillich, Jean-Pierre. "Description of a quantum convolutional code." Physical review letters vol. 91,17 (2003): 177902. doi: https://doi.org/10.1103/PhysRevLett.91.177902
Ollivier H, Tillich JP. Description of a quantum convolutional code. Phys Rev Lett. 2003 Oct 24;91(17):177902. doi: 10.1103/PhysRevLett.91.177902. Epub 2003 Oct 23. PMID: 14611378.
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Early adverse life events are associated with altered brain network architecture in a sex- dependent manner.

Neurobiology of stress

Gupta A, Mayer EA, Acosta JR, Hamadani K, Torgerson C, van Horn JD, Chang L, Naliboff B, Tillisch K, Labus JS.
PMID: 28239631
Neurobiol Stress. 2017 Feb 17;7:16-26. doi: 10.1016/j.ynstr.2017.02.003. eCollection 2017 Dec.

INTRODUCTION: Early adverse life events (EALs) increase the risk for chronic medical and psychiatric disorders by altering early neurodevelopment. The aim of this study was to examine associations between EALs and network properties of core brain regions in the...

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Gupta A, Mayer EA, Acosta JR, et al. Early adverse life events are associated with altered brain network architecture in a sex- dependent manner. Neurobiol Stress. 2017;7:16-26doi: 10.1016/j.ynstr.2017.02.003.
Gupta, A., Mayer, E. A., Acosta, J. R., Hamadani, K., Torgerson, C., van Horn, J. D., Chang, L., Naliboff, B., Tillisch, K., & Labus, J. S. (2017). Early adverse life events are associated with altered brain network architecture in a sex- dependent manner. Neurobiology of stress, 716-26. https://doi.org/10.1016/j.ynstr.2017.02.003
Gupta, Arpana, et al. "Early adverse life events are associated with altered brain network architecture in a sex- dependent manner." Neurobiology of stress vol. 7 (2017): 16-26. doi: https://doi.org/10.1016/j.ynstr.2017.02.003
Gupta A, Mayer EA, Acosta JR, Hamadani K, Torgerson C, van Horn JD, Chang L, Naliboff B, Tillisch K, Labus JS. Early adverse life events are associated with altered brain network architecture in a sex- dependent manner. Neurobiol Stress. 2017 Feb 17;7:16-26. doi: 10.1016/j.ynstr.2017.02.003. eCollection 2017 Dec. PMID: 28239631; PMCID: PMC5318542.
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Towards Low Overhead Magic State Distillation.

Physical review letters

Krishna A, Tillich JP.
PMID: 31491096
Phys Rev Lett. 2019 Aug 16;123(7):070507. doi: 10.1103/PhysRevLett.123.070507.

Magic-state distillation is a resource intensive subroutine for quantum computation. The ratio of noisy input states to output states with an error rate at most ε scales as O(log^{γ}(1/ε)) [S. Bravyi and J. Haah, Magic-state distillation with low overhead,...

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Krishna A, Tillich JP. Towards Low Overhead Magic State Distillation. Phys Rev Lett. 2019;123(7):070507doi: 10.1103/PhysRevLett.123.070507.
Krishna, A., & Tillich, J. P. (2019). Towards Low Overhead Magic State Distillation. Physical review letters, 123(7), 070507. https://doi.org/10.1103/PhysRevLett.123.070507
Krishna, Anirudh, and Tillich, Jean-Pierre. "Towards Low Overhead Magic State Distillation." Physical review letters vol. 123,7 (2019): 070507. doi: https://doi.org/10.1103/PhysRevLett.123.070507
Krishna A, Tillich JP. Towards Low Overhead Magic State Distillation. Phys Rev Lett. 2019 Aug 16;123(7):070507. doi: 10.1103/PhysRevLett.123.070507. PMID: 31491096.
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Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia.

The journal of pain

Labus JS, Mayer EA, Tillisch K, Aagaard KM, Stains J, Broniowska K, Van Remortel C, Tun G, Rapkin A.
PMID: 34029688
J Pain. 2021 Dec;22(12):1586-1605. doi: 10.1016/j.jpain.2021.04.017. Epub 2021 May 23.

Provoked vestibulodynia (PVD) is a chronic pain disorder characterized by local hypersensitivity and severe pain with pressure localized to the vulvar vestibule. Despite decades of study, the lack of identified biomarkers has slowed the development of effective therapies. The...

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Labus JS, Mayer EA, Tillisch K, et al. Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia. J Pain. 2021;22(12):1586-1605doi: 10.1016/j.jpain.2021.04.017.
Labus, J. S., Mayer, E. A., Tillisch, K., Aagaard, K. M., Stains, J., Broniowska, K., Van Remortel, C., Tun, G., & Rapkin, A. (2021). Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia. The journal of pain, 22(12), 1586-1605. https://doi.org/10.1016/j.jpain.2021.04.017
Labus, Jennifer S, et al. "Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia." The journal of pain vol. 22,12 (2021): 1586-1605. doi: https://doi.org/10.1016/j.jpain.2021.04.017
Labus JS, Mayer EA, Tillisch K, Aagaard KM, Stains J, Broniowska K, Van Remortel C, Tun G, Rapkin A. Dysregulation in Sphingolipid Signaling Pathways is Associated With Symptoms and Functional Connectivity of Pain Processing Brain Regions in Provoked Vestibulodynia. J Pain. 2021 Dec;22(12):1586-1605. doi: 10.1016/j.jpain.2021.04.017. Epub 2021 May 23. PMID: 34029688.
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Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement.

Microbiome

Jacobs JP, Gupta A, Bhatt RR, Brawer J, Gao K, Tillisch K, Lagishetty V, Firth R, Gudleski GD, Ellingson BM, Labus JS, Naliboff BD, Lackner JM, Mayer EA.
PMID: 34847963
Microbiome. 2021 Nov 30;9(1):236. doi: 10.1186/s40168-021-01188-6.

BACKGROUND: There is growing recognition that bidirectional signaling between the digestive tract and the brain contributes to irritable bowel syndrome (IBS). We recently showed in a large randomized controlled trial that cognitive behavioral therapy (CBT) reduces IBS symptom severity....

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Jacobs JP, Gupta A, Bhatt RR, et al. Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome. 2021;9(1):236doi: 10.1186/s40168-021-01188-6.
Jacobs, J. P., Gupta, A., Bhatt, R. R., Brawer, J., Gao, K., Tillisch, K., Lagishetty, V., Firth, R., Gudleski, G. D., Ellingson, B. M., Labus, J. S., Naliboff, B. D., Lackner, J. M., & Mayer, E. A. (2021). Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome, 9(1), 236. https://doi.org/10.1186/s40168-021-01188-6
Jacobs, Jonathan P, et al. "Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement." Microbiome vol. 9,1 (2021): 236. doi: https://doi.org/10.1186/s40168-021-01188-6
Jacobs JP, Gupta A, Bhatt RR, Brawer J, Gao K, Tillisch K, Lagishetty V, Firth R, Gudleski GD, Ellingson BM, Labus JS, Naliboff BD, Lackner JM, Mayer EA. Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome. 2021 Nov 30;9(1):236. doi: 10.1186/s40168-021-01188-6. PMID: 34847963; PMCID: PMC8630837.
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