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Showing 1 to 12 of 32 entries
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Transient anti-NMDAR encephalitis in a newborn infant due to transplacental transmission.

Neurology(R) neuroimmunology & neuroinflammation

Hilderink M, Titulaer MJ, Schreurs MW, Keizer K, Bunt JE.
PMID: 26140282
Neurol Neuroimmunol Neuroinflamm. 2015 Jun 18;2(4):e126. doi: 10.1212/NXI.0000000000000126. eCollection 2015 Aug.

No abstract available.

A new synthesis of p-hydroxy phenylglycine and some analogues from p-benzoquinone.

Organic letters

Titulaer GT, Zhu J, Klunder AJ, Zwanenburg B.
PMID: 10814354
Org Lett. 2000 Feb 24;2(4):473-5. doi: 10.1021/ol9913183.

[reaction: see text] A new route to p-hydroxy phenylglycine and N-substituted analogues has been developed starting from p-benzoquinone. 1,2-Addition of methyl lithioacetate to p-benzoquinone and subsequent quenching of the oxygen anion with methyl chloroformate, followed by an elimination-addition reaction...

Label-free peptide profiling of Orbitrap™ full mass spectra.

BMC research notes

Titulaer MK, de Costa D, Stingl C, Dekker LJ, Sillevis Smitt PA, Luider TM.
PMID: 21272362
BMC Res Notes. 2011 Jan 27;4:21. doi: 10.1186/1756-0500-4-21.

BACKGROUND: We developed a new version of the open source software package Peptrix that can yet compare large numbers of Orbitrap™ LC-MS data. The peptide profiling results for Peptrix on MS1 spectra were compared with those obtained from a...

Anti-NMDAR Encephalitis in the Netherlands, Focusing on Late-Onset Patients and Antibody Test Accuracy.

Neurology(R) neuroimmunology & neuroinflammation

Bastiaansen AEM, de Bruijn MAAM, Schuller SL, Martinez-Hernandez E, Brenner J, Paunovic M, Crijnen YS, Mulder MJHL, Schreurs MWJ, de Graaff E, Smitt PAE, Neuteboom RF, de Vries JM, Titulaer MJ.
PMID: 34937737
Neurol Neuroimmunol Neuroinflamm. 2021 Dec 22;9(2). doi: 10.1212/NXI.0000000000001127. Print 2022 Mar.

BACKGROUND AND OBJECTIVES: To describe the clinical features of anti-NMDAR encephalitis, emphasizing on late-onset patients and antibody test characteristics in serum and CSF.METHODS: Nationwide observational Dutch cohort study, in patients diagnosed with anti-NMDAR encephalitis between 2007 and 2019.RESULTS: One...

Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management.

Journal of neurology, neurosurgery, and psychiatry

Abboud H, Probasco JC, Irani S, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer MJ.
PMID: 33649022
J Neurol Neurosurg Psychiatry. 2021 Jul;92(7):757-768. doi: 10.1136/jnnp-2020-325300. Epub 2021 Mar 01.

The objective of this paper is to evaluate available evidence for each step in autoimmune encephalitis management and provide expert opinion when evidence is lacking. The paper approaches autoimmune encephalitis as a broad category rather than focusing on individual...

Post-mortem ultrasound and freezing of rabbit meat: Effects on the physicochemical quality and weight loss.

Ultrasonics sonochemistry

Carrillo-Lopez LM, Robledo D, Martínez V, Huerta-Jimenez M, Titulaer M, Alarcon-Rojo AD, Chavez-Martinez A, Luna-Rodriguez L, Garcia-Flores LR.
PMID: 34619483
Ultrason Sonochem. 2021 Nov;79:105766. doi: 10.1016/j.ultsonch.2021.105766. Epub 2021 Oct 01.

High intensity ultrasound (HIU) is a technique with the potential to improve meat quality, however, more research is needed on its application within the chain of cold storage and freezing. This study evaluates the effect of HIU (40 kHz,...

Frequency and Characterization of Movement Disorders in Anti-IgLON5 Disease.

Neurology

Gaig C, Compta Y, Heidbreder A, Marti MJ, Titulaer MJ, Crijnen Y, Högl B, Lewerenz J, Erro ME, Garcia-Monco JC, Nigro P, Tambasco N, Patalong-Ogiewa M, Erdler M, Macher S, Berger-Sieczkowski E, Höftberger R, Geis C, Hutterer M, Milán-Tomás A, Martin-Bastida A, Manzanares LL, Quintas S, Höglinger GU, Möhn N, Schoeberl F, Thaler FS, Asioli GM, Provini F, Plazzi G, Berganzo K, Blaabjerg M, Brüggemann N, Farias T, Ng CF, Giordana C, Herrero-San Martín A, Huebra L, Kotschet K, Liendl H, Montojo T, Morata C, Perez JP, Puertas I, Seifert-Held T, Seitz C, Simabukuro MM, Tellez N, Villacieros-Álvarez J, Willekens B, Sabater L, Iranzo A, Cano JS, Dalmau J, Graus F.
PMID: 34380749
Neurology. 2021 Aug 11; doi: 10.1212/WNL.0000000000012639. Epub 2021 Aug 11.

OBJECTIVE: Anti-IgLON5 disease is a recently described neurological disease that shares features of autoimmunity and neurodegeneration. Abnormal movements appear to be frequent and important but have not been characterized and are under-reported. Here we describe the frequency and types...

Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes.

Neurology(R) neuroimmunology & neuroinflammation

Graus F, Vogrig A, Muñiz-Castrillo S, Antoine JG, Desestret V, Dubey D, Giometto B, Irani SR, Joubert B, Leypoldt F, McKeon A, Prüss H, Psimaras D, Thomas L, Titulaer MJ, Vedeler CA, Verschuuren JJ, Dalmau J, Honnorat J.
PMID: 34006622
Neurol Neuroimmunol Neuroinflamm. 2021 May 18;8(4). doi: 10.1212/NXI.0000000000001014. Print 2021 Jul.

OBJECTIVE: The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs) requires an increasing understanding of their clinical, immunologic, and oncologic heterogeneity. The 2004 PNS criteria are partially outdated due to advances in PNS research in the last 16 years leading...

Emergency front-of-neck airway by ENT surgeons and residents: A dutch national survey.

Laryngoscope investigative otolaryngology

Bruijstens L, Titulaer I, Scheffer GJ, Steegers M, van den Hoogen F.
PMID: 30410989
Laryngoscope Investig Otolaryngol. 2018 Oct 31;3(5):356-363. doi: 10.1002/lio2.183. eCollection 2018 Oct.

OBJECTIVES: ENT surgeons and anesthesiologists work closely together in managing challenging airway cases. Sharing knowledge, experiences, and expectations interdisciplinary is essential in order to facilitate decision-making and adequate management in emergency front-of-neck airway cases.METHODS: A survey was performed, to...

No Evidence for the Involvement of Leiomodin-1 Antibodies in the Pathogenesis of Onchocerciasis-Associated Epilepsy.

Pathogens (Basel, Switzerland)

Hotterbeekx A, Vieri MK, Ramberger M, Jozefzoon-Aghai A, Mandro M, Tepage F, Dusabimana A, Kumar-Singh S, Titulaer MJ, Colebunders R.
PMID: 34357995
Pathogens. 2021 Jul 05;10(7). doi: 10.3390/pathogens10070845.

Nodding syndrome has been suggested to be triggered by neurotoxic leiomodin-1 auto-antibodies cross-reacting with

SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence.

Research square

Chen S, Han Y, Yang L, Kim T, Nair M, Harschnitz O, Wang P, Zhu J, Koo SY, Tang X, Lacko L, Chandar V, Bram Y, Zhang T, Zhang W, He F, Caicedo J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler RL, Canoll P, Goldman J, Przedborski S, Schwartz R, Ho D, Studer L.
PMID: 34031650
Res Sq. 2021 May 21; doi: 10.21203/rs.3.rs-513461/v1.

COVID-19 patients commonly present with neurological signs of central nervous system (CNS) and/or peripheral nervous system dysfunction. However, which neural cells are permissive to infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been controversial. Here, we show...

The role of antibody indexes in clinical virology.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Shamier MC, Bogers S, Yusuf E, van Splunter M, Ten Berge JCEM, Titulaer M, van Kampen JJA, GeurtsvanKessel CH.
PMID: 33813108
Clin Microbiol Infect. 2021 Sep;27(9):1207-1211. doi: 10.1016/j.cmi.2021.03.015. Epub 2021 Apr 01.

BACKGROUND: Serological techniques are an essential part of the diagnostic tools used in clinical virology. Among these techniques, antibody indexes are not novel, but do require specific expertise. Their niche has expanded substantially in recent years due to increasing...

Showing 1 to 12 of 32 entries