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Interaction of basal forebrain cholinergic neurons with the glucocorticoid system in stress regulation and cognitive impairment.

Frontiers in aging neuroscience

Paul S, Jeon WK, Bizon JL, Han JS.
PMID: 25883567
Front Aging Neurosci. 2015 Apr 02;7:43. doi: 10.3389/fnagi.2015.00043. eCollection 2015.

A substantial number of studies on basal forebrain (BF) cholinergic neurons (BFCN) have provided compelling evidence for their role in the etiology of stress, cognitive aging, Alzheimer's disease (AD), and other neurodegenerative diseases. BFCN project to a broad range...

[Burnt-out professionals, disillusioned professionals or professionals with psychopathological disorders?].

Atencion primaria

Tizón JL.
PMID: 15087078
Aten Primaria. 2004 Apr 15;33(6):326-30. doi: 10.1016/s0212-6567(04)70801-x.

No abstract available.

High-resolution record of Northern Hemisphere climate extending into the last interglacial period.

Nature

Andersen KK, Azuma N, Barnola JM, Bigler M, Biscaye P, Caillon N, Chappellaz J, Clausen HB, Dahl-Jensen D, Fischer H, Flückiger J, Fritzsche D, Fujii Y, Goto-Azuma K, Grønvold K, Gundestrup NS, Hansson M, Huber C, Hvidberg CS, Johnsen SJ, Jonsell U, Jouzel J, Kipfstuhl S, Landais A, Leuenberger M, Lorrain R, Masson-Delmotte V, Miller H, Motoyama H, Narita H, Popp T, Rasmussen SO, Raynaud D, Rothlisberger R, Ruth U, Samyn D, Schwander J, Shoji H, Siggard-Andersen ML, Steffensen JP, Stocker T, Sveinbjörnsdóttir AE, Svensson A, Takata M, Tison JL, Thorsteinsson T, Watanabe O, Wilhelms F, White JW.
PMID: 15356621
Nature. 2004 Sep 09;431(7005):147-51. doi: 10.1038/nature02805.

Two deep ice cores from central Greenland, drilled in the 1990s, have played a key role in climate reconstructions of the Northern Hemisphere, but the oldest sections of the cores were disturbed in chronology owing to ice folding near...

Characterizing cognitive aging of spatial and contextual memory in animal models.

Frontiers in aging neuroscience

Foster TC, Defazio RA, Bizon JL.
PMID: 22988436
Front Aging Neurosci. 2012 Sep 12;4:12. doi: 10.3389/fnagi.2012.00012. eCollection 2012.

Episodic memory, especially memory for contextual or spatial information, is particularly vulnerable to age-related decline in humans and animal models of aging. The continuing improvement of virtual environment technology for testing humans signifies that widely used procedures employed in...

Characterizing cognitive aging of working memory and executive function in animal models.

Frontiers in aging neuroscience

Bizon JL, Foster TC, Alexander GE, Glisky EL.
PMID: 22988438
Front Aging Neurosci. 2012 Sep 12;4:19. doi: 10.3389/fnagi.2012.00019. eCollection 2012.

Executive functions supported by prefrontal cortical (PFC) systems provide essential control and planning mechanisms to guide goal-directed behavior. As such, age-related alterations in executive functions can mediate profound and widespread deficits on a diverse array of neurocognitive processes. Many...

Vildagliptin, a DPP4 inhibitor, alleviates diabetes-associated cognitive deficits by decreasing the levels of apoptosis-related proteins in the rat hippocampus.

Experimental and therapeutic medicine

Zhang DD, Shi N, Fang H, Ma L, Wu WP, Zhang YZ, Tian JL, Tian LB, Kang K, Chen S.
PMID: 29805536
Exp Ther Med. 2018 Jun;15(6):5100-5106. doi: 10.3892/etm.2018.6016. Epub 2018 Apr 02.

Cognitive impairment is a prevalent but underestimated complication of diabetes, which can cause spatial memory and learning deficits. In the present study, a streptozotocin-induced type 2 diabetic rat model was employed to investigate the effects of vildagliptin, a new...

Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination.

Frontiers in systems neuroscience

Johnson SA, Turner SM, Lubke KN, Cooper TL, Fertal KE, Bizon JL, Maurer AP, Burke SN.
PMID: 30687032
Front Syst Neurosci. 2019 Jan 10;12:72. doi: 10.3389/fnsys.2018.00072. eCollection 2018.

Memory requires similar episodes with overlapping features to be represented distinctly, a process that is disrupted in many clinical conditions as well as normal aging. Data from humans have linked this ability to activity in hippocampal CA3 and dentate...

Nightside condensation of iron in an ultrahot giant exoplanet.

Nature

Ehrenreich D, Lovis C, Allart R, Zapatero Osorio MR, Pepe F, Cristiani S, Rebolo R, Santos NC, Borsa F, Demangeon O, Dumusque X, González Hernández JI, Casasayas-Barris N, Ségransan D, Sousa S, Abreu M, Adibekyan V, Affolter M, Allende Prieto C, Alibert Y, Aliverti M, Alves D, Amate M, Avila G, Baldini V, Bandy T, Benz W, Bianco A, Bolmont É, Bouchy F, Bourrier V, Broeg C, Cabral A, Calderone G, Pallé E, Cegla HM, Cirami R, Coelho JMP, Conconi P, Coretti I, Cumani C, Cupani G, Dekker H, Delabre B, Deiries S, D'Odorico V, Di Marcantonio P, Figueira P, Fragoso A, Genolet L, Genoni M, Génova Santos R, Hara N, Hughes I, Iwert O, Kerber F, Knudstrup J, Landoni M, Lavie B, Lizon JL, Lendl M, Lo Curto G, Maire C, Manescau A, Martins CJAP, Mégevand D, Mehner A, Micela G, Modigliani A, Molaro P, Monteiro M, Monteiro M, Moschetti M, Müller E, Nunes N, Oggioni L, Oliveira A, Pariani G, Pasquini L, Poretti E, Rasilla JL, Redaelli E, Riva M, Santana Tschudi S, Santin P, Santos P, Segovia Milla A, Seidel JV, Sosnowska D, Sozzetti A, Spanò P, Suárez Mascareño A, Tabernero H, Tenegi F, Udry S, Zanutta A, Zerbi F.
PMID: 32161364
Nature. 2020 Apr;580(7805):597-601. doi: 10.1038/s41586-020-2107-1. Epub 2020 Mar 11.

Ultrahot giant exoplanets receive thousands of times Earth's insolation

A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging.

The journals of gerontology. Series A, Biological sciences and medical sciences

Hernandez CM, Hernandez AR, Hoffman JM, King PH, McMahon LL, Buford TW, Carter C, Bizon JL, Burke SN.
PMID: 34623396
J Gerontol A Biol Sci Med Sci. 2022 Jan 07;77(1):e19-e33. doi: 10.1093/gerona/glab301.

Neuroscience has a rich history of studies focusing on neurobiology of aging. However, much of the aging studies in neuroscience occur outside of the gerosciences. The goal of this primer is 2-fold: first, to briefly highlight some of the...

A Neuroscience Primer for Integrating Geroscience with the Neurobiology of Aging.

The journals of gerontology. Series A, Biological sciences and medical sciences

Hernandez CM, Hernandez AR, Hoffman JM, King PH, McMahon LL, Buford TW, Carter C, Bizon JL, Burke SN.
PMID: 34623396
J Gerontol A Biol Sci Med Sci. 2021 Oct 08; doi: 10.1093/gerona/glab301. Epub 2021 Oct 08.

Neuroscience has a rich history of studies focusing on neurobiology of aging. However, much of the aging studies in neuroscience occur outside of the gerosciences. The goal of this primer is twofold: First, to briefly highlight some of the...

Bridging the gap: A geroscience primer for neuroscientists with potential collaborative applications.

The journals of gerontology. Series A, Biological sciences and medical sciences

Hoffman JM, Hernandez CM, Hernandez AR, Bizon JL, Burke SN, Carter CS, Buford TW.
PMID: 34653247
J Gerontol A Biol Sci Med Sci. 2021 Oct 15; doi: 10.1093/gerona/glab314. Epub 2021 Oct 15.

While neurodegenerative diseases can strike at any age, the majority of afflicted individuals are diagnosed at older ages. Due to the important impact of age in disease diagnosis, the field of neuroscience could greatly benefit from the many of...

Synthesis, crystal structures, anticancer activities and molecular docking studies of novel thiazolidinone Cu(II) and Fe(III) complexes targeting lysosomes: special emphasis on their binding to DNA/BSA.

Dalton transactions (Cambridge, England : 2003)

Shao J, Zhang Q, Wei J, Yuchi Z, Cao P, Li SQ, Wang S, Xu JY, Yang S, Zhang Y, Wei JX, Tian JL.
PMID: 34473154
Dalton Trans. 2021 Oct 05;50(38):13387-13398. doi: 10.1039/d1dt02180j.

Novel [CuL

Showing 1 to 12 of 67 entries